Abstract: The main aim is to perform mutational analysis of CTLA4 gene Exon 1 in SLE patients. A total of 61 SLE patients fulfilling “American College of Rheumatology (ACR) criteria" and 61 controls were enrolled in this study. The region of CTLA4 gene exon 1 was amplified by using Step-down PCR technique. Extracted DNA of band 354 bp was sequenced to analyze mutations in the exon-1 of CTLA-4 gene. Further, protein sequences were identified from nucleotide sequences of CTLA4 Exon 1 by using Expasy software and through Blast P software it was found that CTLA4 protein sequences of Pakistani SLE patients were similar to that of Chinese SLE population. No variations were found after patients sequences were compared with that of the control sequence. Furthermore it was found that CTLA4 protein sequences of Pakistani SLE patients were similar to that of Chinese SLE population. Thus CTLA4 gene may not be responsible for an autoimmune disease SLE.
Abstract: Nanoemulsions are a class of emulsions with a droplet
size in the range of 50–500 nm and have attracted a great deal of
attention in recent years because it is unique characteristics. The
physicochemical properties of nanoemulsion suggests that it can be
successfully used to recover the residual oil which is trapped in the
fine pore of reservoir rock by capillary forces after primary and
secondary recovery. Oil-in-water nanoemulsion which can be formed
by high-energy emulsification techniques using specific surfactants
can reduce oil-water interfacial tension (IFT) by 3-4 orders of
magnitude. The present work is aimed on characterization of oil-inwater
nanoemulsion in terms of its phase behavior, morphological
studies; interfacial energy; ability to reduce the interfacial tension and
understanding the mechanisms of mobilization and displacement of
entrapped oil blobs by lowering interfacial tension both at the
macroscopic and microscopic level. In order to investigate the
efficiency of oil-water nanoemulsion in enhanced oil recovery
(EOR), experiments were performed to characterize the emulsion in
terms of their physicochemical properties and size distribution of the
dispersed oil droplet in water phase. Synthetic mineral oil and a series
of surfactants were used to prepare oil-in-water emulsions.
Characterization of emulsion shows that it follows pseudo-plastic
behaviour and drop size of dispersed oil phase follows lognormal
distribution. Flooding experiments were also carried out in a
sandpack system to evaluate the effectiveness of the nanoemulsion as
displacing fluid for enhanced oil recovery. Substantial additional
recoveries (more than 25% of original oil in place) over conventional
water flooding were obtained in the present investigation.
Abstract: In this paper, an algorithm for detecting and attenuating
puff noises frequently generated under the mobile environment is
proposed. As a baseline system, puff detection system is designed
based on Gaussian Mixture Model (GMM), and 39th Mel Frequency
Cepstral Coefficient (MFCC) is extracted as feature parameters. To
improve the detection performance, effective acoustic features for puff
detection are proposed. In addition, detected puff intervals are
attenuated by high-pass filtering. The speech recognition rate was
measured for evaluation and confusion matrix and ROC curve are used
to confirm the validity of the proposed system.
Abstract: To analyze the behavior of Petri nets, the accessibility
graph and Model Checking are widely used. However, if the
analyzed Petri net is unbounded then the accessibility graph becomes
infinite and Model Checking can not be used even for small Petri
nets. ECATNets [2] are a category of algebraic Petri nets. The main
feature of ECATNets is their sound and complete semantics based on
rewriting logic [8] and its language Maude [9]. ECATNets analysis
may be done by using techniques of accessibility analysis and Model
Checking defined in Maude. But, these two techniques supported by
Maude do not work also with infinite-states systems. As a category
of Petri nets, ECATNets can be unbounded and so infinite systems.
In order to know if we can apply accessibility analysis and Model
Checking of Maude to an ECATNet, we propose in this paper an
algorithm allowing the detection if the ECATNet is bounded or not.
Moreover, we propose a rewriting logic based tool implementing this
algorithm. We show that the development of this tool using the
Maude system is facilitated thanks to the reflectivity of the rewriting
logic. Indeed, the self-interpretation of this logic allows us both the
modelling of an ECATNet and acting on it.
Abstract: Gas chromatography (GC) is the most widely used
technique in analytical chemistry. However, GC has high initial cost
and requires frequent maintenance. This paper examines the
feasibility and potential of using a neural network model as an
alternative whenever GC is unvailable. It can also be part of system
verification on the performance of GC for preventive maintenance
activities. It shows the performance of MultiLayer Perceptron (MLP)
with Backpropagation structure. Results demonstrate that neural
network model when trained using this structure provides an
adequate result and is suitable for this purpose. cm.
Abstract: New lead-free ferroelectric relaxor ceramics were
prepared by conventional solid-state synthesis in the BaTiO3-Bi2O3-
Y2O3 systems. Some of these ceramics present a ferroelectric relaxor
with transition temperature close to room temperature. These new
materials are very interesting for applications and can replace leadbased
ceramic to prevent the toxic pollutions during the preparation
state. In the other hand, the energy band diagram shows the
potentiality of these compounds for the solar energy conversion.
Thus, some compositions have been tested successfully for H2
production upon visible light. The best activity occurs in alkaline
media with a rate evolution of about 0.15 mL g-1 mn-1 and a quantum
yield of 1% under polychromatic light.
Abstract: We propose an enhanced key management scheme
based on Key Infection, which is lightweight scheme for tiny sensors.
The basic scheme, Key Infection, is perfectly secure against node
capture and eavesdropping if initial communications after node
deployment is secure. If, however, an attacker can eavesdrop on
the initial communications, they can take the session key. We use
common neighbors for each node to generate the session key. Each
node has own secret key and shares it with its neighbor nodes. Then
each node can establish the session key using common neighbors-
secret keys and a random number. Our scheme needs only a few
communications even if it uses neighbor nodes- information. Without
losing the lightness of basic scheme, it improves the resistance against
eavesdropping on the initial communications more than 30%.
Abstract: In this paper, a study on the modes of collapse of
compress- expand members are presented. Compress- expand member
is a compact, multiple-combined cylinders, to be proposed as energy
absorbers. Previous studies on the compress- expand member have
clarified its energy absorption efficiency, proposed an approximate
equation to describe its deformation characteristics and also
highlighted the improvement that it has brought. However, for the
member to be practical, the actual range of geometrical dimension that
it can maintain its applicability must be investigated. In this study,
using a virtualized materials that comply the bilinear hardening law,
Finite element Method (FEM) analysis on the collapse modes of
compress- expand member have been conducted. Deformation maps
that plotted the member's collapse modes with regards to the member's
geometric and material parameters were then presented in order to
determine the dimensional range of each collapse modes.
Abstract: Sugarcane Shoots is an abundantly available
residual resources consisting of lignocelluloses which take it into
the benefit. The present study was focused on utilizing of
sugarcane shoot for reducing sugar production as a substrate in
ethanol production. Physical and chemical pretreatments of
sugarcane shoot were investigated. Results showed that the size of
sugarcane shoot influenced the cellulose content. The maximum
cellulose yield (60 %) can be obtained from alkaline pretreated
sugarcane shoot with 1.0 M NaOH at 30 oC for 90 min. The
cellulose yield reached up to 93.9% (w/w). Enzymatically
hydrolyzed of cellulosic residual in 0.04 citrate buffer (pH 5) with
celluclast 1.5L (0.7 FPU/ml) resulted in the highest amount of
reducing sugar at a rate of 32.1 g/l after 4 h incubation at 50°C,
and 100 oC for 5 min . Cellulose conversion was 55.5%.
Abstract: Evaluation of educational portals is an important
subject area that needs more attention from researchers. A university
that has an educational portal which is difficult to use and interact by
teachers or students or management staff can reduce the position and
reputation of the university. Therefore, it is important to have the
ability to make an evaluation of the quality of e-services the
university provide to improve them over time.
The present study evaluates the usability of the Information
Technology Faculty portal at University of Benghazi. Two evaluation
methods were used: a questionnaire-based method and an online
automated tool-based method. The first method was used to measure
the portal's external attributes of usability (Information, Content and
Organization of the portal, Navigation, Links and Accessibility,
Aesthetic and Visual Appeal, Performance and Effectiveness and
educational purpose) from users' perspectives, while the second
method was used to measure the portal's internal attributes of
usability (number and size of HTML files, number and size of images,
load time, HTML check errors, browsers compatibility problems,
number of bad and broken links), which cannot be perceived by the
users. The study showed that some of the usability aspects have been
found at the acceptable level of performance and quality, and some
others have been found otherwise. In general, it was concluded that
the usability of IT faculty educational portal generally acceptable.
Recommendations and suggestions to improve the weakness and
quality of the portal usability are presented in this study.
Abstract: Nowadays, biometrical characterizations of Artemia
cysts are used as one of the most important factors in the study of
Artemia populations and intraspecific particularity; meanwhile these
characters can be used as economical indices. For example, typically
high hatching efficiency is possible due to the small diameter of
cysts (high number per gram); therefore small diameter of cysts
show someway high quality of cysts. This study was performed
during a ten year period, including two different ecological
conditions: rainy and drought. It is important from two different
aspects because it covers alteration of A. urmiana during ten years
also its variation in the best and worst environmental situations in
which salinity increased from 173.8 ppt in 1994 to 280.8 ppt in
2003/4. In this study the biometrical raw data of Artemia urmiana
cysts at seven stations from the Urmia Lake in 1994 and their seven
identical locations at 26 studied stations in 2003/4 were reanalyzed
again and compared together. Biometrical comparison of untreated
and decapsulated cysts in each of the seven similar stations showed a
highly significant variation between 1994 and 2003/4. Based on this
study, in whole stations the untreated and decapsulated cysts from
1994 were larger than cysts of 2003/4 without any exception. But
there was no logical relationship between salinity and chorion
thickness in the Urmia Lake. With regard to PCA analyses the
stations of two different studied years certainly have been separated
with factor 1 from each other. In conclusion, the interaction between
genetic and environmental factors can determine and explain
variation in the range of cysts diameter in Artemia.
Abstract: The study of proteomics reached unexpected levels of
interest, as a direct consequence of its discovered influence over
some complex biological phenomena, such as problematic diseases
like cancer. This paper presents a new technique that allows for an
accurate analysis of the human interactome network. It is basically
a two-step analysis process that involves, at first, the detection of
each protein-s absolute importance through the betweenness centrality
computation. Then, the second step determines the functionallyrelated
communities of proteins. For this purpose, we use a community
detection technique that is based on the edge betweenness
calculation. The new technique was thoroughly tested on real biological
data and the results prove some interesting properties of those proteins that are involved in the carcinogenesis process. Apart from its
experimental usefulness, the novel technique is also computationally
effective in terms of execution times. Based on the analysis- results, some topological features of cancer mutated proteins are presented
and a possible optimization solution for cancer drugs design is suggested.
Abstract: Computerized lip reading has been one of the most
actively researched areas of computer vision in recent past because
of its crime fighting potential and invariance to acoustic environment.
However, several factors like fast speech, bad pronunciation,
poor illumination, movement of face, moustaches and beards make
lip reading difficult. In present work, we propose a solution for
automatic lip contour tracking and recognizing letters of English
language spoken by speakers using the information available from
lip movements. Level set method is used for tracking lip contour
using a contour velocity model and a feature vector of lip movements
is then obtained. Character recognition is performed using modified
k nearest neighbor algorithm which assigns more weight to nearer
neighbors. The proposed system has been found to have accuracy
of 73.3% for character recognition with speaker lip movements as
the only input and without using any speech recognition system in
parallel. The approach used in this work is found to significantly
solve the purpose of lip reading when size of database is small.
Abstract: This paper shows a new method for design of fuzzy observers for Takagi-Sugeno systems. The method is based on Linear matrix inequalities (LMIs) and it allows to insert H constraint into the design procedure. The speed of estimation can tuned be specification of a decay rate of the observer closed loop system. We discuss here also the influence of parametric uncertainties at the output control system stability.
Abstract: Project managers are the ultimate responsible for the
overall characteristics of a project, i.e. they should deliver the project
on time with minimum cost and with maximum quality. It is vital for
any manager to decide a trade-off between these conflicting
objectives and they will be benefited of any scientific decision
support tool. Our work will try to determine optimal solutions (rather
than a single optimal solution) from which the project manager will
select his desirable choice to run the project. In this paper, the
problem in project scheduling notated as
(1,T|cpm,disc,mu|curve:quality,time,cost) will be studied. The
problem is multi-objective and the purpose is finding the Pareto
optimal front of time, cost and quality of a project
(curve:quality,time,cost), whose activities belong to a start to finish
activity relationship network (cpm) and they can be done in different
possible modes (mu) which are non-continuous or discrete (disc), and
each mode has a different cost, time and quality . The project is
constrained to a non-renewable resource i.e. money (1,T). Because
the problem is NP-Hard, to solve the problem, a meta-heuristic is
developed based on a version of genetic algorithm specially adapted
to solve multi-objective problems namely FastPGA. A sample project
with 30 activities is generated and then solved by the proposed
method.
Abstract: A new numerical scheme based on the H1-Galerkin mixed finite element method for a class of second-order pseudohyperbolic equations is constructed. The proposed procedures can be split into three independent differential sub-schemes and does not need to solve a coupled system of equations. Optimal error estimates are derived for both semidiscrete and fully discrete schemes for problems in one space dimension. And the proposed method dose not requires the LBB consistency condition. Finally, some numerical results are provided to illustrate the efficacy of our method.
Abstract: In this paper real money demand function is analyzed
within multivariate time-series framework. Cointegration approach is
used (Johansen procedure) assuming interdependence between
money demand determinants, which are nonstationary variables. This
will help us to understand the behavior of money demand in Croatia,
revealing the significant influence between endogenous variables in
vector autoregrression system (VAR), i.e. vector error correction
model (VECM). Exogeneity of the explanatory variables is tested.
Long-run money demand function is estimated indicating slow speed
of adjustment of removing the disequilibrium. Empirical results
provide the evidence that real industrial production and exchange
rate explains the most variations of money demand in the long-run,
while interest rate is significant only in short-run.
Abstract: It is not easy to imagine how the existing city can be
converted to the principles of sustainability, however, the need for
innovation, requires a pioneering phase which must address the main
problems of rehabilitation of the operating models of the city. Today,
however, there is a growing awareness that the identification and
implementation of policies and measures to promote the adaptation,
resilience and reversibility of the city, require the contribution of our
discipline. This breakthrough is present in some recent international
experiences of Climate Plans, in which the envisaged measures are
closely interwoven with those of urban planning. These experiences,
provide some answers principle questions, such as: how the strategies
to combat climate can be integrated in the instruments of the local
government; what new and specific analysis must be introduced in
urban planning in order to understand the issues of urban
sustainability, and how the project compares with different spatial
scales.
Abstract: Solid waste can be considered as an urban burden or
as a valuable resource depending on how it is managed. To meet the
rising demand for energy and to address environmental concerns, a
conversion from conventional energy systems to renewable resources
is essential. For the sustainability of human civilization, an
environmentally sound and techno-economically feasible waste
treatment method is very important to treat recyclable waste. Several
technologies are available for realizing the potential of solid waste as
an energy source, ranging from very simple systems for disposing of
dry waste to more complex technologies capable of dealing with
large amounts of industrial waste. There are three main pathways for
conversion of waste material to energy: thermo chemical,
biochemical and physicochemical. This paper investigates the thermo
chemical conversion of solid waste for energy recovery. The
processes, advantages and dis-advantages of various thermo chemical
conversion processes are discussed and compared. Special attention
is given to Gasification process as it provides better solutions
regarding public acceptance, feedstock flexibility, near-zero
emissions, efficiency and security. Finally this paper presents
comparative statements of thermo chemical processes and introduces
an integrated waste management system.
Abstract: A computational platform is presented in this
contribution. It has been designed as a virtual laboratory to be used
for exploring optimization algorithms in biological problems. This
platform is built on a blackboard-based agent architecture. As a test
case, the version of the platform presented here is devoted to the
study of protein folding, initially with a bead-like description of the
chain and with the widely used model of hydrophobic and polar
residues (HP model). Some details of the platform design are
presented along with its capabilities and also are revised some
explorations of the protein folding problems with different types of
discrete space. It is also shown the capability of the platform to
incorporate specific tools for the structural analysis of the runs in
order to understand and improve the optimization process.
Accordingly, the results obtained demonstrate that the ensemble of
computational tools into a single platform is worthwhile by itself,
since experiments developed on it can be designed to fulfill different
levels of information in a self-consistent fashion. By now, it is being
explored how an experiment design can be useful to create a
computational agent to be included within the platform. These
inclusions of designed agents –or software pieces– are useful for the
better accomplishment of the tasks to be developed by the platform.
Clearly, while the number of agents increases the new version of the
virtual laboratory thus enhances in robustness and functionality.