Abstract: An optimal control problem for a mathematical model of efficiency of antiviral therapy in hepatitis B virus infections is considered. The aim of the study is to control the new viral production, block the new infection cells and maintain the number of uninfected cells in the given range. The optimal controls represent the efficiency of antiviral therapy in inhibiting viral production and preventing new infections. Defining the cost functional, the optimal control problem is converted into the constrained optimization problem and the first order optimality system is derived. For the numerical simulation, we propose the steepest descent algorithm based on the adjoint variable method. A computer program in MATLAB is developed for the numerical simulations.
Abstract: This paper deals with a periodic-review substitutable
inventory system for a finite and an infinite number of periods. Here
an upward substitution structure, a substitution of a more costly item
by a less costly one, is assumed, with two products. At the beginning
of each period, a stochastic demand comes for the first item only,
which is quality-wise better and hence costlier. Whenever an arriving
demand finds zero inventory of this product, a fraction of unsatisfied
customers goes for its substitutable second item. An optimal ordering
policy has been derived for each period. The results are illustrated
with numerical examples. A sensitivity analysis has been done to
examine how sensitive the optimal solution and the maximum profit
are to the values of the discount factor, when there is a large number
of periods.
Abstract: Today, Higher Education in a global scope is subordinated to the greater institutional controls through the policies of the Quality of Education. These include processes of over evaluation of all the academic activities: students- and professors- performance, educational logistics, managerial standards for the administration of institutions of higher education, as well as the establishment of the imaginaries of excellence and prestige as the foundations on which universities of the XXI century will focus their present and future goals and interests. But at the same time higher education systems worldwide are facing the most profound crisis of sense and meaning and attending enormous mutations in their identity. Based in a qualitative research approach, this paper shows the social configurations that the scholars at the Universities in Mexico build around the discourse of the Quality of Education, and how these policies put in risk the social recognition of these individuals.
Abstract: In the last decades to supply the various and different
demands of clients, a lot of manufacturers trend to use the mixedmodel
assembly line (MMAL) in their production lines, since this
policy make possible to assemble various and different models of the
equivalent goods on the same line with the MTO approach.
In this article, we determine the sequence of (MMAL) line, with
applying the kitting approach and planning of rest time for general
workers to reduce the wastages, increase the workers effectiveness
and apply the sector of lean production approach.
This Multi-objective sequencing problem solved in small size with
GAMS22.2 and PSO meta heuristic in 10 test problems and compare
their results together and conclude that their results are very similar
together, next we determine the important factors in computing the
cost, which improving them cost reduced. Since this problem, is NPhard
in large size, we use the particle swarm optimization (PSO)
meta-heuristic for solving it. In large size we define some test
problems to survey it-s performance and determine the important
factors in calculating the cost, that by change or improved them
production in minimum cost will be possible.
Abstract: In response to address different development challenges, Tanzania is striving to achieve its fourth attribute of the National Development Vision, i.e. to have a well educated and learned society by the year 2025. One of the most cost effective methods that can reach a large part of the society in a short time is to integrate ICT in education through e-learning initiatives. However, elearning initiatives are challenged by limited or lack of connectivity to majority of secondary schools, especially those in rural and remote areas. This paper has explores the possibility for rural secondary school to access online e-Learning resources from a centralized e- Learning Management System (e-LMS). The scope of this paper is limited to schools that have computers irrespective of internet connectivity, resulting in two categories schools; those with internet access and those without. Different connectivity configurations have been proposed according to the ICT infrastructure status of the respective schools. However, majority of rural secondary schools in Tanzania have neither computers nor internet connection. Therefore this is a challenge to be addressed for the disadvantaged schools to benefit from e-Learning initiatives.
Abstract: The purpose of this research was develop a biological
nutrient removal (BNR) system which has low energy consumption, sludge production, and land usage. These indicate that BNR system could be a alternative of future wastewater treatment in ubiquitous
city(U-city). Organics and nitrogen compounds could be removed by this system so that secondary or tertiary stages of wastewater treatment satisfy their standards. This system was composed of oxic and anoxic
filter filed with PVDC and POM media. Anoxic/oxic filter system operated under empty bed contact time of 4 hours by increasing
recirculation ratio from 0 to 100 %. The system removals of total nitrogen and COD were 76.3% and 93%, respectively. To be observed
internal behavior in this system SCOD, NH3-N, and NO3-N were
conducted and removal shows range of 25~100%, 59~99%, and
70~100%, respectively.
Abstract: In this paper, the least-squares design of variable fractional-delay (VFD) finite impulse response (FIR) digital differentiators is proposed. The used transfer function is formulated so that Farrow structure can be applied to realize the designed system. Also, the symmetric characteristics of filter coefficients are derived, which leads to the complexity reduction by saving almost a half of the number of coefficients. Moreover, all the elements of related vectors or matrices for the optimal process can be represented in closed forms, which make the design easier. Design example is also presented to illustrate the effectiveness of the proposed method.
Abstract: This study examined a habitat-suitability assessment method namely the Ecological Niche Factor Analysis (ENFA). A virtual species was created and then dispatched in a geographic information system model of a real landscape in three historic scenarios: (1) spreading, (2) equilibrium, and (3) overabundance. In each scenario, the virtual species was sampled and these simulated data sets were used as inputs for the ENFA to reconstruct the habitat suitability model. The 'equilibrium' scenario gives the highest quantity and quality among three scenarios. ENFA was sensitive to the distribution scenarios but not sensitive to sample sizes. The use of a virtual species proved to be a very efficient method, allowing one to fully control the quality of the input data as well as to accurately evaluate the predictive power of the analyses.
Abstract: Mammographic images and data analysis to
facilitate modelling or computer aided diagnostic (CAD) software development should best be done using a common database that can handle various mammographic image file
formats and relate these to other patient information.
This would optimize the use of the data as both primary
reporting and enhanced information extraction of research data could be performed from the single dataset. One desired
improvement is the integration of DICOM file header information into the database, as an efficient and reliable source of supplementary patient information intrinsically
available in the images.
The purpose of this paper was to design a suitable database to link and integrate different types of image files and gather common information that can be further used for research
purposes. An interface was developed for accessing, adding,
updating, modifying and extracting data from the common
database, enhancing the future possible application of the data in CAD processing.
Technically, future developments envisaged include the creation of an advanced search function to selects image files
based on descriptor combinations. Results can be further used for specific CAD processing and other research. Design of a
user friendly configuration utility for importing of the required fields from the DICOM files must be done.
Abstract: Creating3D environments, including characters and
cities, is a significantly time consuming process due to a large amount
of workinvolved in designing and modelling.There have been a
number of attempts to automatically generate 3D objects employing
shape grammars. However it is still too early to apply the mechanism
to real problems such as real-time computer games.The purpose of this
research is to introduce a time efficient and cost effective method to
automatically generatevarious 3D objects for real-time 3D games.
This Shape grammar-based real-time City Generation (RCG) model is
a conceptual model for generating 3Denvironments in real-time and
can be applied to 3D gamesoranimations. The RCG system can
generate even a large cityby applying fundamental principles of shape
grammars to building elementsin various levels of detailin real-time.
Abstract: The stem cells have ability to differentiated
themselves through mitotic cell division and various range of
specialized cell types. Cellular differentiation is a way by which few
specialized cell develops into more specialized.This paper studies the
fundamental problem of computational schema for an artificial neural
network based on chemical, physical and biological variables of
state. By doing this type of study system could be model for a viable
propagation of various economically important stem cells
differentiation. This paper proposes various differentiation outcomes
of artificial neural network into variety of potential specialized cells
on implementing MATLAB version 2009. A feed-forward back
propagation kind of network was created to input vector (five input
elements) with single hidden layer and one output unit in output
layer. The efficiency of neural network was done by the assessment
of results achieved from this study with that of experimental data
input and chosen target data. The propose solution for the efficiency
of artificial neural network assessed by the comparatative analysis of
“Mean Square Error" at zero epochs. There are different variables of
data in order to test the targeted results.
Abstract: This paper proposes the requirements and design of
RFID based system for SFC (Shop Floor Control) in order to achieve
the factory real time controllability, Allowing to develop EManufacturing
System. The detailed logical specifications of the core
functions and the design diagrams of RFID based system are
developed. Then RFID deployment in E-Manufacturing systems is
investigated..
Abstract: The Virtual Reality (VR) is becoming increasingly
important for business, education, and entertainment, therefore VR
technology have been applied for training purposes in the areas of
military, safety training and flying simulators. In particular, the
superior and high reliability VR training system is very important in
immersion. Manipulation training in immersive virtual environments
is difficult partly because users must do without the hap contact with
real objects they rely on in the real world to orient themselves and
their manipulated.
In this paper, we create a convincing questionnaire of immersion
and an experiment to assess the influence of immersion on
performance in VR training system. The Immersion Questionnaire
(IQ) included spatial immersion, Psychological immersion, and
Sensory immersion. We show that users with a training system
complete visual attention and detection of signals. Twenty subjects
were allocated to a factorial design consisting of two different VR
systems (Desktop VR and Projector VR). The results indicated that
different VR representation methods significantly affected the
participants- Immersion dimensions.
Abstract: This study has investigated a vehicle Lumped
Parameter Model (LPM) in frontal crash. There are several ways for
determining spring and damper characteristics and type of problem
shall be considered as system identification. This study use Genetic
Algorithm (GA) procedure, being an effective procedure in case of
optimization issues, for optimizing errors, between target data
(experimental data) and calculated results (being obtained by
analytical solving). In this study analyzed model in 5-DOF then
compared our results with 5-DOF serial model. Finally, the response
of model due to external excitement is investigated.
Abstract: This paper proposes improved delay-dependent stability conditions of the linear time-delay systems of neutral type. The proposed methods employ a suitable Lyapunov-Krasovskii’s functional and a new form of the augmented system. New delay-dependent stability criteria for the systems are established in terms of Linear matrix inequalities (LMIs) which can be easily solved by various effective optimization algorithms. Numerical examples showed that the proposed method is effective and can provide less conservative results.
Abstract: Reverse engineering of full-genomic interaction networks based on compendia of expression data has been successfully applied for a number of model organisms. This study adapts these approaches for an important non-model organism: The major human fungal pathogen Candida albicans. During the infection process, the pathogen can adapt to a wide range of environmental niches and reversibly changes its growth form. Given the importance of these processes, it is important to know how they are regulated. This study presents a reverse engineering strategy able to infer fullgenomic interaction networks for C. albicans based on a linear regression, utilizing the sparseness criterion (LASSO). To overcome the limited amount of expression data and small number of known interactions, we utilize different prior-knowledge sources guiding the network inference to a knowledge driven solution. Since, no database of known interactions for C. albicans exists, we use a textmining system which utilizes full-text research papers to identify known regulatory interactions. By comparing with these known regulatory interactions, we find an optimal value for global modelling parameters weighting the influence of the sparseness criterion and the prior-knowledge. Furthermore, we show that soft integration of prior-knowledge additionally improves the performance. Finally, we compare the performance of our approach to state of the art network inference approaches.
Abstract: The International Classification of Primary Care (ICPC), which belongs to the WHO Family of International Classifications (WHO-FIC), has a low granularity, which is convenient for describing general medical practice. However, its lack of specificity makes it useful to be used along with an interface terminology. An international survey has been performed, using a questionnaire sent by email to experts from 25 countries, in order to describe the terminologies interfacing with ICPC. Eleven interface terminologies have been identified, developed in Argentina, Australia, Belgium (2), Canada, Denmark, France, Germany, Norway, South Africa, and The Netherlands. Globally, these systems have been poorly assessed until now.
Abstract: The multi-agent system for processing Bio-signals
will help the medical practitioners to have a standard examination
procedure stored in web server. Web Servers supporting any standard
Search Engine follow all possible combinations of the search
keywords as an input by the user to a Search Engine. As a result, a
huge number of Web-pages are shown in the Web browser. It also
helps the medical practitioner to interact with the expert in the field
his need in order to make a proper judgment in the diagnosis phase
[3].A web server uses a web server plug in to establish and
maintained the medical practitioner to make a fast analysis. If the
user uses the web server client can get a related data requesting their
search. DB agent, EEG / ECG / EMG agents- user placed with
difficult aspects for updating medical information-s in web server.
Abstract: This article concerned with the translation of Quranic
verses to Braille symbols, by using Visual basic program. The
system has the ability to translate the special vibration for the Quran.
This study limited for the (Noun + Scoon) vibrations. It builds on an
existing translation system that combines a finite state machine with
left and right context matching and a set of translation rules. This
allows to translate the Arabic language from text to Braille symbols
after detect the vibration for the Quran verses.
Abstract: A multi-agent system is developed here to predict
monthly details of the upcoming peak of the 24th solar magnetic
cycle. While studies typically predict the timing and magnitude of
cycle peaks using annual data, this one utilizes the unsmoothed
monthly sunspot number instead. Monthly numbers display more
pronounced fluctuations during periods of strong solar magnetic
activity than the annual sunspot numbers. Because strong magnetic
activities may cause significant economic damages, predicting
monthly variations should provide different and perhaps helpful
information for decision-making purposes. The multi-agent system
developed here operates in two stages. In the first, it produces twelve
predictions of the monthly numbers. In the second, it uses those
predictions to deliver a final forecast. Acting as expert agents, genetic
programming and neural networks produce the twelve fits and
forecasts as well as the final forecast. According to the results
obtained, the next peak is predicted to be 156 and is expected to
occur in October 2011- with an average of 136 for that year.