Abstract: Glutathione S-transferase was purified from human
erythrocytes and effects of some polyphenols were investigated on
the enzyme activity. The purification procedure was performed on
Glutathione-Agarose affinity chromatography after preparation of
erythrocytes hemolysate with a yield of 81%. The purified enzyme
showed a single band on the SDS-PAGE. The effects of some
poliphenolic compounds such as catechin, dopa, dopamine, progallol
and catechol were examined on the in vitro GST activity. Catechin
was determined to be inhibitor for the enzyme, but others were not
effective on the enzyme as inhibitors or activators. IC50 value -the
concentration of inhibitor which reduces enzyme activity by 50%-
was estimated to be 10 mM. Ki constants were also calculated as 6.38
± 0,70 mM with GSH substrate, and 3.86 ± 0,78 mM with CDNB
substrate using the equations of graphs for the inhibitor, and its
inhibition type was determined as non-competitive.
Abstract: A precision CMOS chopping amplifier is adopted in this work to improve a CMOS temperature sensor high sensitive enough for intracranial temperature monitoring. An amplified temperature sensitivity of 18.8 ± 3*0.2 mV/oC is attained over the temperature range from 20 oC to 80 oC from a given 10 samples of the same wafer. The analog frontend design outputs the temperature dependent and the temperature independent signals which can be directly interfaced to a 10 bit ADC to accomplish an accurate temperature instrumentation system.
Abstract: The classification of the protein structure is commonly
not performed for the whole protein but for structural domains, i.e.,
compact functional units preserved during evolution. Hence, a first
step to a protein structure classification is the separation of the
protein into its domains. We approach the problem of protein domain
identification by proposing a novel graph theoretical algorithm. We
represent the protein structure as an undirected, unweighted and
unlabeled graph which nodes correspond the secondary structure
elements of the protein. This graph is call the protein graph. The
domains are then identified as partitions of the graph corresponding
to vertices sets obtained by the maximization of an objective function,
which mutually maximizes the cycle distributions found in the
partitions of the graph. Our algorithm does not utilize any other kind
of information besides the cycle-distribution to find the partitions. If
a partition is found, the algorithm is iteratively applied to each of
the resulting subgraphs. As stop criterion, we calculate numerically
a significance level which indicates the stability of the predicted
partition against a random rewiring of the protein graph. Hence,
our algorithm terminates automatically its iterative application. We
present results for one and two domain proteins and compare our
results with the manually assigned domains by the SCOP database
and differences are discussed.
Abstract: The present work was conducted for the synthesis of
nano size zerovalent iron (nZVI) and hexavalent chromium (Cr(VI))
removal as a highly toxic pollutant by using this nanoparticles. Batch
experiments were performed to investigate the effects of Cr(VI),
nZVI concentration, pH of solution and contact time variation on
the removal efficiency of Cr(VI). nZVI was synthesized by
reduction of ferric chloride using sodium borohydrid. SEM and
XRD examinations applied for determination of particle size and
characterization of produced nanoparticles. The results showed that
the removal efficiency decreased with Cr(VI) concentration and pH
of solution and increased with adsorbent dosage and contact time.
The Langmuir and Freundlich isotherm models were used for the
adsorption equilibrium data and the Langmuir isotherm model was
well fitted. Nanoparticle ZVI presented an outstanding ability to
remove Cr(VI) due to high surface area, low particle size and high
inherent activity.
Abstract: This study evaluates the performance of horizontal
subsurface flow constructed wetland (HSSF-CW) for the removal of
chlorinated resin and fatty acids (RFAs) from pulp and paper mill
wastewater. The dimensions of the treatment system were 3.5 m x 1.5
m x 0.28 m with surface area of 5.25 m2, filled with fine sand and
gravel. The cell was planted with an ornamental plant species Canna
indica. The removal efficiency of chlorinated RFAs was in the range
of 92-96% at the hydraulic retention time (HRT) of 5.9 days. Plant
biomass and soil (sand and gravel) were analyzed for chlorinated
RFAs content. No chlorinated RFAs were detected in plant biomass
but detected in soil samples. Mass balance studies of chlorinated
RFAs in HSSF-CW were also carried out.
Abstract: In the last years, the computers have increased their capacity of calculus and networks, for the interconnection of these machines. The networks have been improved until obtaining the actual high rates of data transferring. The programs that nowadays try to take advantage of these new technologies cannot be written using the traditional techniques of programming, since most of the algorithms were designed for being executed in an only processor,in a nonconcurrent form instead of being executed concurrently ina set of processors working and communicating through a network.This paper aims to present the ongoing development of a new system for the reconfiguration of grouping of computers, taking into account these new technologies.
Abstract: Shape optimization of the airfoil with high aspect ratio
of long endurance unmanned aerial vehicle (UAV) is performed by the
multi-objective optimization technology coupled with computational
fluid dynamics (CFD). For predicting the aerodynamic characteristics
around the airfoil the high-fidelity Navier-Stokes solver is employed
and SMOGA (Simple Multi-Objective Genetic Algorithm), which is
developed by authors, is used for solving the multi-objective
optimization problem. To obtain the optimal solutions of the design
variable (i.e., sectional airfoil profile, wing taper ratio and sweep) for
high performance of UAVs, both the lift and lift-to-drag ratio are
maximized whereas the pitching moment should be minimized,
simultaneously. It is found that the lift force and lift-to-drag ratio are
linearly dependent and a unique and dominant solution are existed.
However, a trade-off phenomenon is observed between the lift-to-drag
ratio and pitching moment. As the result of optimization, sixty-five
(65) non-dominated Pareto individuals at the cutting edge of design
spaces that is decided by airfoil shapes can be obtained.
Abstract: Urbanization and regionalization are two different
approaches when it comes to economical structures and development,
infrastructure and mobility, quality of life and living, education,
social cohesion and many other topics. At first glance, the structures
associated with urbanization and regionalization seems to be
contradicting. This paper discusses possibilities of transfer and
cooperation between rural and urban structures. An empirical
investigation contributed to reveal scenarios of supposable forms of
exchange and cooperation of remote rural areas and big cities.
Abstract: In this paper; we are interested principally in dynamic modelling of quadrotor while taking into account the high-order nonholonomic constraints in order to develop a new control scheme as well as the various physical phenomena, which can influence the dynamics of a flying structure. These permit us to introduce a new state-space representation. After, the use of Backstepping approach for the synthesis of tracking errors and Lyapunov functions, a sliding mode controller is developed in order to ensure Lyapunov stability, the handling of all system nonlinearities and desired tracking trajectories. Finally simulation results are also provided in order to illustrate the performances of the proposed controller.
Abstract: The paper considers a novel modular and intrinsically safe redundant robotic system with biologically inspired actuators (pneumatic artificial muscles and rubber bellows actuators). Similarly to the biological systems, the stiffness of the internal parallel modules, representing 2 DOF joints in the serial robotic chains, is controlled by co-activation of opposing redundant actuator groups in the null-space of the module Jacobian, without influencing the actual robot position. The decoupled position/stiffness control allows the realization of variable joint stiffness according to different force-displacement relationships. The variable joint stiffness, as well as limited pneumatic muscle/bellows force ability, ensures internal system safety that is crucial for development of human-friendly robots intended for human-robot collaboration. The initial experiments with the system prototype demonstrate the capabilities of independently, simultaneously controlling both joint (Cartesian) motion and joint stiffness. The paper also presents the possible industrial applications of snake-like robots built using the new modules.
Abstract: An optimized design of E/O and O/E for access points
of WiMAX RoF was carried out by evaluating RCE. The use of the
DFB-LD, a low input-impedance driving, a low distortion PIN-PD,
and a high gain EPHEMT amplifier is promising the cost-effective
design. For the uplink RoF design, the use of EDFA and EP-HEMT
amplifiers is necessity.
Abstract: In this paper, the steady-state temperature of a sample 500 KW two rotor one stator Non-slotted axial flux permanent magnet motor is calculated using the finite element simulator software package. Due to the high temperature in various parts of the machine, especially at stator winding, a cooling system is designed for the motor and the temperature is recalculated. The results show that the temperature obtained for the parts is within the permissible range.
Abstract: Following the laser ablation studies leading to a
theory of nuclei confinement by a Debye layer mechanism, we
present here numerical evaluations for the known stable nuclei where
the Coulomb repulsion is included as a rather minor component
especially for lager nuclei. In this research paper the required
physical conditions for the formation and stability of nuclei
particularly endothermic nuclei with mass number greater than to
which is an open astrophysical question have been investigated.
Using the Debye layer mechanism, nuclear surface energy, Fermi
energy and coulomb repulsion energy it is possible to find conditions
under which the process of nucleation is permitted in early universe.
Our numerical calculations indicate that about 200 second after the
big bang at temperature of about 100 KeV and subrelativistic region
with nucleon density nearly equal to normal nuclear density namely,
10cm all endothermic and exothermic nuclei have been
formed.
Abstract: A digital system is proposed for low power 100-
channel neural recording system in this paper, which consists of 100
amplifiers, 100 analog-to-digital converters (ADC), digital controller
and baseband, transceiver for data link and RF command link. The
proposed system is designed in a 0.18 μm CMOS process and 65 nm
CMOS process.
Abstract: Among various HLM techniques, the Multivariate Hierarchical Linear Model (MHLM) is desirable to use, particularly when multivariate criterion variables are collected and the covariance structure has information valuable for data analysis. In order to reflect prior information or to obtain stable results when the sample size and the number of groups are not sufficiently large, the Bayes method has often been employed in hierarchical data analysis. In these cases, although the Markov Chain Monte Carlo (MCMC) method is a rather powerful tool for parameter estimation, Procedures regarding MCMC have not been formulated for MHLM. For this reason, this research presents concrete procedures for parameter estimation through the use of the Gibbs samplers. Lastly, several future topics for the use of MCMC approach for HLM is discussed.
Abstract: This paper describes the project and development of a
very low-cost and small electronic prototype, especially designed for
monitoring and controlling existing home automation alarm systems
(intruder, smoke, gas, flood, etc.), via TCP/IP, with a typical web
browser. Its use will allow home owners to be immediately alerted
and aware when an alarm event occurs, and being also able to
interact with their home automation alarm system, disarming, arming
and watching event alerts, with a personal wireless Wi-Fi PDA or
smartphone logged on to a dedicated predefined web page, and using
also a PC or Laptop.
Abstract: Deep cold rolling (DCR) is a cold working process, which easily produces a smooth and work-hardened surface by plastic deformation of surface irregularities. In the present study, the influence of main deep cold rolling process parameters on the surface roughness and the hardness of AISI 4140 steel were studied by using fractional factorial design of experiments. The assessment of the surface integrity aspects on work material was done, in terms of identifying the predominant factor amongst the selected parameters, their order of significance and setting the levels of the factors for minimizing surface roughness and/or maximizing surface hardness. It was found that the ball diameter, rolling force, initial surface roughness and number of tool passes are the most pronounced parameters, which have great effects on the work piece-s surface during the deep cold rolling process. A simple, inexpensive and newly developed DCR tool, with interchangeable collet for using different ball diameters, was used throughout the experimental work presented in this paper.
Abstract: The main aim of this study was to examine whether
people understand indicative conditionals on the basis of syntactic
factors or on the basis of subjective conditional probability. The
second aim was to investigate whether the conditional probability of
q given p depends on the antecedent and consequent sizes or derives
from inductive processes leading to establish a link of plausible cooccurrence
between events semantically or experientially associated.
These competing hypotheses have been tested through a 3 x 2 x 2 x 2
mixed design involving the manipulation of four variables: type of
instructions (“Consider the following statement to be true", “Read the
following statement" and condition with no conditional statement);
antecedent size (high/low); consequent size (high/low); statement
probability (high/low). The first variable was between-subjects, the
others were within-subjects. The inferences investigated were Modus
Ponens and Modus Tollens. Ninety undergraduates of the Second
University of Naples, without any prior knowledge of logic or
conditional reasoning, participated in this study.
Results suggest that people understand conditionals in a syntactic
way rather than in a probabilistic way, even though the perception of
the conditional probability of q given p is at least partially involved in
the conditionals- comprehension. They also showed that, in presence
of a conditional syllogism, inferences are not affected by the
antecedent or consequent sizes. From a theoretical point of view these
findings suggest that it would be inappropriate to abandon the idea
that conditionals are naturally understood in a syntactic way for the
idea that they are understood in a probabilistic way.
Abstract: In this work, we first give in what fields Fp, the cubic
root of unity lies in F*p, in Qp and in K*p where Qp and K*p denote
the sets of quadratic and non-zero cubic residues modulo p. Then we
use these to obtain some results on the classification of the Bachet
elliptic curves y2 ≡ x3 +a3 modulo p, for p ≡ 1 (mod 6) is prime.
Abstract: This paper presents a low-voltage low-power differential linear transconductor with near rail-to-rail input swing. Based on the current-mirror OTA topology, the proposed transconductor combines the Flipped Voltage Follower (FVF) technique to linearize the transconductor behavior that leads to class- AB linear operation and the virtual transistor technique to lower the effective threshold voltages of the transistors which offers an advantage in terms of low supply requirement. Design of the OTA has been discussed. It operates at supply voltages of about ±0.8V. Simulation results for 0.18μm TSMC CMOS technology show a good input range of 1Vpp with a high DC gain of 81.53dB and a total harmonic distortion of -40dB at 1MHz for an input of 1Vpp. The main aim of this paper is to present and compare new OTA design with high transconductance, which has a potential to be used in low voltage applications.