Abstract: Disordered function of maniphalanx and difficulty with
ambulation will occur insofar as a human has a failure in the spinal
marrow. Cervical spondylotic myelopathy as one of the myelopathy
emanates from not only external factors but also increased age. In
addition, the diacrisis is difficult since cervical spondylotic
myelopathy is evaluated by a doctor-s neurological remark and
imaging findings. As a quantitative method for measuring the degree
of disability, hand-operated triangle step test (for short, TST) has
formulated. In this research, a full automatic triangle step counter
apparatus is designed and developed to measure the degree of
disability in an accurate fashion according to the principle of TST. The
step counter apparatus whose shape is a low triangle pole displays the
number of stepping upon each corner. Furthermore, the apparatus has
two modes of operation. Namely, one is for measuring the degree of
disability and the other for rehabilitation exercise. In terms of
usefulness, clinical practice should be executed before too long.
Abstract: Deaths from cardiovascular diseases have decreased substantially over the past two decades, largely as a result of advances in acute care and cardiac surgery. These developments have produced a growing population of patients who have survived a myocardial infarction. These patients need to be continuously monitored so that the initiation of treatment can be given within the crucial golden hour. The available conventional methods of monitoring mostly perform offline analysis and restrict the mobility of these patients within a hospital or room. Hence the aim of this paper is to design a Portable Cardiac Telemedicine System to aid the patients to regain their independence and return to an active work schedule, there by improving the psychological well being. The portable telemedicine system consists of a Wearable ECG Transmitter (WET) and a slightly modified mobile phone, which has an inbuilt ECG analyzer. The WET is placed on the body of the patient that continuously acquires the ECG signals from the high-risk cardiac patients who can move around anywhere. This WET transmits the ECG to the patient-s Bluetooth enabled mobile phone using blue tooth technology. The ECG analyzer inbuilt in the mobile phone continuously analyzes the heartbeats derived from the received ECG signals. In case of any panic condition, the mobile phone alerts the patients care taker by an SMS and initiates the transmission of a sample ECG signal to the doctor, via the mobile network.
Abstract: The ElectroEncephaloGram (EEG) is useful for
clinical diagnosis and biomedical research. EEG signals often
contain strong ElectroOculoGram (EOG) artifacts produced
by eye movements and eye blinks especially in EEG recorded
from frontal channels. These artifacts obscure the underlying
brain activity, making its visual or automated inspection
difficult. The goal of ocular artifact removal is to remove
ocular artifacts from the recorded EEG, leaving the underlying
background signals due to brain activity. In recent times,
Independent Component Analysis (ICA) algorithms have
demonstrated superior potential in obtaining the least
dependent source components. In this paper, the independent
components are obtained by using the JADE algorithm (best
separating algorithm) and are classified into either artifact
component or neural component. Neural Network is used for
the classification of the obtained independent components.
Neural Network requires input features that exactly represent
the true character of the input signals so that the neural
network could classify the signals based on those key
characters that differentiate between various signals. In this
work, Auto Regressive (AR) coefficients are used as the input
features for classification. Two neural network approaches
are used to learn classification rules from EEG data. First, a
Polynomial Neural Network (PNN) trained by GMDH (Group
Method of Data Handling) algorithm is used and secondly,
feed-forward neural network classifier trained by a standard
back-propagation algorithm is used for classification and the
results show that JADE-FNN performs better than JADEPNN.
Abstract: Certifications such as the Passive House Standard aim to reduce the final space heating energy demand of residential buildings. Space conditioning, notably heating, is responsible for nearly 70% of final residential energy consumption in Europe. There is therefore significant scope for the reduction of energy consumption through improvements to the energy efficiency of residential buildings. However, these certifications totally overlook the energy embodied in the building materials used to achieve this greater operational energy efficiency. The large amount of insulation and the triple-glazed high efficiency windows require a significant amount of energy to manufacture. While some previous studies have assessed the life cycle energy demand of passive houses, including their embodied energy, these rely on incomplete assessment techniques which greatly underestimate embodied energy and can lead to misleading conclusions. This paper analyses the embodied and operational energy demands of a case study passive house using a comprehensive hybrid analysis technique to quantify embodied energy. Results show that the embodied energy is much more significant than previously thought. Also, compared to a standard house with the same geometry, structure, finishes and number of people, a passive house can use more energy over 80 years, mainly due to the additional materials required. Current building energy efficiency certifications should widen their system boundaries to include embodied energy in order to reduce the life cycle energy demand of residential buildings.
Abstract: The paper proposes a new concept in developing
collaborative design system. The concept framework involves
applying simulation of supply chain management to collaborative
design called – 'SCM–Based Design Tool'. The system is developed
particularly to support design activities and to integrate all facilities
together. The system is aimed to increase design productivity and
creativity. Therefore, designers and customers can collaborate by the
system since conceptual design. JAG: Jewelry Art Generator based
on artificial intelligence techniques is integrated into the system.
Moreover, the proposed system can support users as decision tool
and data propagation. The system covers since raw material supply
until product delivery. Data management and sharing information are
visually supported to designers and customers via user interface. The
system is developed on Web–assisted product development
environment. The prototype system is presented for Thai jewelry
industry as a system prototype demonstration, but applicable for
other industry.
Abstract: Information hiding, especially watermarking is a
promising technique for the protection of intellectual property rights.
This technology is mainly advanced for multimedia but the same has
not been done for text. Web pages, like other documents, need a
protection against piracy. In this paper, some techniques are
proposed to show how to hide information in web pages using some
features of the markup language used to describe these pages. Most
of the techniques proposed here use the white space to hide
information or some varieties of the language in representing
elements. Experiments on a very small page and analysis of five
thousands web pages show that these techniques have a wide
bandwidth available for information hiding, and they might form a
solid base to develop a robust algorithm for web page watermarking.
Abstract: Organizational culture fosters innovation, and innovation is the main engine to be sustained within the uncertainty market. Like other countries, the construction industry significantly contributes to the economy, society and technology of Malaysia, yet, innovation is still considered slow compared to other industries such as manufacturing. Given the important role of an architect as the key player and the contributor of new ideas in the construction industry, there is a call to identify the issue and improve the current situation by focusing on the architectural firms. In addition, the existing studies tend to focus only on a few dimensions of organizational culture and very few studies consider whether innovation is being generated or adopted. Hence, the present research tends to fill in the gap by identifying the organizational cultures that foster or hinder innovation generation and/or innovation adoption, and propose a model of organizational culture and innovation generation and/or adoption.
Abstract: RF performance of SOI CMOS device has attracted
significant amount of interest recently. In order to improve RF
parameters, Strained Si/Relaxed Si0.8Ge0.2 investigated as a
replacement for Si technology .Enhancement of carrier mobility
associated with strain engineering makes Strained Si a promising
candidate for improving RF performance of CMOS technology.
From the simulation, the cut-off frequency is estimated to be 224
GHZ, whereas in SOI at similar bias is about 188 GHZ. Therefore,
Strained Si exhibits 19% improvement in cut-off frequency over
similar Si counterpart. In this paper, Ion/Ioff ratio is studied as one of
the key parameters in logic and digital application. Strained Si/SiGe
demonstrates better Ion/Ioff characteristic than SOI, in similar channel
length of 100 nm.Another important key analog figures of merit such
as Early Voltage (VEA) ,transconductance vs drain current (gm /Ids)
are studied. They introduce the efficiency of the devices to convert
dc power into ac frequency.
Abstract: The modern telecommunication industry demands
higher capacity networks with high data rate. Orthogonal frequency
division multiplexing (OFDM) is a promising technique for high data
rate wireless communications at reasonable complexity in wireless
channels. OFDM has been adopted for many types of wireless
systems like wireless local area networks such as IEEE 802.11a, and
digital audio/video broadcasting (DAB/DVB). The proposed research
focuses on a concatenated coding scheme that improve the
performance of OFDM based wireless communications. It uses a
Redundant Residue Number System (RRNS) code as the outer code
and a convolutional code as the inner code. Here, a direct conversion
of analog signal to residue domain is done to reduce the conversion
complexity using sigma-delta based parallel analog-to-residue
converter. The bit error rate (BER) performances of the proposed
system under different channel conditions are investigated. These
include the effect of additive white Gaussian noise (AWGN),
multipath delay spread, peak power clipping and frame start
synchronization error. The simulation results show that the proposed
RRNS-Convolutional concatenated coding (RCCC) scheme provides
significant improvement in the system performance by exploiting the
inherent properties of RRNS.
Abstract: Selection of maize (Zea mays) hybrids with wide adaptability across diverse farming environments is important, prior to recommending them to achieve a high rate of hybrid adoption. Grain yield of 14 maize hybrids, tested in a randomized completeblock design with four replicates across 22 environments in Iran, was analyzed using site regression (SREG) stability model. The biplot technique facilitates a visual evaluation of superior genotypes, which is useful for cultivar recommendation and mega-environment identification. The objectives of this study were (i) identification of suitable hybrids with both high mean performance and high stability (ii) to determine mega-environments for maize production in Iran. Biplot analysis identifies two mega-environments in this study. The first mega-environments included KRM, KSH, MGN, DZF A, KRJ, DRB, DZF B, SHZ B, and KHM, where G10 hybrid was the best performing hybrid. The second mega-environment included ESF B, ESF A, and SHZ A, where G4 hybrid was the best hybrid. According to the ideal-hybrid biplot, G10 hybrid was better than all other hybrids, followed by the G1 and G3 hybrids. These hybrids were identified as best hybrids that have high grain yield and high yield stability. GGE biplot analysis provided a framework for identifying the target testing locations that discriminates genotypes that are high yielding and stable.
Abstract: Crucial information barely visible to the human eye is
often embedded in a series of low resolution images taken of the
same scene. Super resolution reconstruction is the process of
combining several low resolution images into a single higher
resolution image. The ideal algorithm should be fast, and should add
sharpness and details, both at edges and in regions without adding
artifacts. In this paper we propose a super resolution blind
reconstruction technique for linearly degraded images. In our
proposed technique the algorithm is divided into three parts an image
registration, wavelets based fusion and an image restoration. In this
paper three low resolution images are considered which may sub
pixels shifted, rotated, blurred or noisy, the sub pixel shifted images
are registered using affine transformation model; A wavelet based
fusion is performed and the noise is removed using soft thresolding.
Our proposed technique reduces blocking artifacts and also
smoothens the edges and it is also able to restore high frequency
details in an image. Our technique is efficient and computationally
fast having clear perspective of real time implementation.
Abstract: The operation performance of a valveless micro-pump
is strongly dependent on the shape of connected nozzle/diffuser and
Reynolds number. The aims of present work are to compare the
performance curves of micropump with the original straight
nozzle/diffuser and contoured nozzle/diffuser under different back
pressure conditions. The tested valveless micropumps are assembled
of five pieces of patterned PMMA plates with hot-embracing
technique. The structures of central chamber, the inlet/outlet
reservoirs and the connected nozzle/diffuser are fabricated with laser
cutting machine. The micropump is actuated with circular-type PZT
film embraced on the bottom of central chamber. The deformation of
PZT membrane with various input voltages is measured with a
displacement laser probe. A simple testing facility is also constructed
to evaluate the performance curves for comparison.
In order to observe the evaluation of low Reynolds number
multiple vortex flow patterns within the micropump during suction
and pumping modes, the unsteady, incompressible laminar
three-dimensional Reynolds-averaged Navier-Stokes equations are
solved. The working fluid is DI water with constant thermo-physical
properties. The oscillating behavior of PZT film is modeled with the
moving boundary wall in way of UDF program. With the dynamic
mesh method, the instants pressure and velocity fields are obtained
and discussed.Results indicated that the volume flow rate is not
monotony increased with the oscillating frequency of PZT film,
regardless of the shapes of nozzle/diffuser. The present micropump
can generate the maximum volume flow rate of 13.53 ml/min when
the operation frequency is 64Hz and the input voltage is 140 volts.
The micropump with contoured nozzle/diffuser can provide 7ml/min
flow rate even when the back pressure is up to 400 mm-H2O. CFD
results revealed that the flow central chamber was occupied with
multiple pairs of counter-rotating vortices during suction and
pumping modes. The net volume flow rate over a complete
oscillating periodic of PZT
Abstract: Ethanol is generally used as a therapeutic reagent against Hepatocellular carcinoma (HCC or hepatoma) worldwide, as it can induce Hepatocellular carcinoma cell apoptosis at low concentration through a multifactorial process regulated by several unknown proteins. This paper provides a simple and available proteomic strategy for exploring differentially expressed proteins in the apoptotic pathway. The appropriate concentrations of ethanol required to induce HepG2 cell apoptosis were first assessed by MTT assay, Gisma and fluorescence staining. Next, the central proteins involved in the apoptosis pathway processs were determined using 2D-PAGE, SDS-PAGE, and bio-software analysis. Finally the downregulation of two proteins, AFP and survivin, were determined by immunocytochemistry and reverse transcriptase PCR (RT-PCR) technology. The simple, useful method demonstrated here provides a new approach to proteomic analysis in key bio-regulating process including proliferation, differentiation, apoptosis, immunity and metastasis.
Abstract: This paper presents an advance in monitoring and
process control of surface roughness in CNC machine for the turning
and milling processes. An integration of the in-process monitoring
and process control of the surface roughness is proposed and
developed during the machining process by using the cutting force
ratio. The previously developed surface roughness models for turning
and milling processes of the author are adopted to predict the inprocess
surface roughness, which consist of the cutting speed, the
feed rate, the tool nose radius, the depth of cut, the rake angle, and
the cutting force ratio. The cutting force ratios obtained from the
turning and the milling are utilized to estimate the in-process surface
roughness. The dynamometers are installed on the tool turret of CNC
turning machine and the table of 5-axis machining center to monitor
the cutting forces. The in-process control of the surface roughness
has been developed and proposed to control the predicted surface
roughness. It has been proved by the cutting tests that the proposed
integration system of the in-process monitoring and the process
control can be used to check the surface roughness during the cutting
by utilizing the cutting force ratio.
Abstract: 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) catalyzes the conversion of HMG-CoA to mevalonate using NADPH and the enzyme is involved in rate-controlling step of mevalonate. Inhibition of HMGR is considered as effective way to lower cholesterol levels so it is drug target to treat hypercholesterolemia, major risk factor of cardiovascular disease. To discover novel HMGR inhibitor, we performed structure-based pharmacophore modeling combined with molecular dynamics (MD) simulation. Four HMGR inhibitors were used for MD simulation and representative structure of each simulation were selected by clustering analysis. Four structure-based pharmacophore models were generated using the representative structure. The generated models were validated used in virtual screening to find novel scaffolds for inhibiting HMGR. The screened compounds were filtered by applying drug-like properties and used in molecular docking. Finally, four hit compounds were obtained and these complexes were refined using energy minimization. These compounds might be potential leads to design novel HMGR inhibitor.
Abstract: This paper explores the effectiveness of machine
learning techniques in detecting firms that issue fraudulent financial
statements (FFS) and deals with the identification of factors
associated to FFS. To this end, a number of experiments have been
conducted using representative learning algorithms, which were
trained using a data set of 164 fraud and non-fraud Greek firms in the
recent period 2001-2002. The decision of which particular method to
choose is a complicated problem. A good alternative to choosing
only one method is to create a hybrid forecasting system
incorporating a number of possible solution methods as components
(an ensemble of classifiers). For this purpose, we have implemented
a hybrid decision support system that combines the representative
algorithms using a stacking variant methodology and achieves better
performance than any examined simple and ensemble method. To
sum up, this study indicates that the investigation of financial
information can be used in the identification of FFS and underline the
importance of financial ratios.
Abstract: In single trial analysis, when using Principal
Component Analysis (PCA) to extract Visual Evoked Potential
(VEP) signals, the selection of principal components (PCs) is an
important issue. We propose a new method here that selects only
the appropriate PCs. We denote the method as selective eigen-rate
(SER). In the method, the VEP is reconstructed based on the rate
of the eigen-values of the PCs. When this technique is applied on
emulated VEP signals added with background
electroencephalogram (EEG), with a focus on extracting the
evoked P3 parameter, it is found to be feasible. The improvement
in signal to noise ratio (SNR) is superior to two other existing
methods of PC selection: Kaiser (KSR) and Residual Power (RP).
Though another PC selection method, Spectral Power Ratio (SPR)
gives a comparable SNR with high noise factors (i.e. EEGs), SER
give more impressive results in such cases. Next, we applied SER
method to real VEP signals to analyse the P3 responses for
matched and non-matched stimuli. The P3 parameters extracted
through our proposed SER method showed higher P3 response for
matched stimulus, which confirms to the existing neuroscience
knowledge. Single trial PCA using KSR and RP methods failed to
indicate any difference for the stimuli.
Abstract: Chronic conditions carry with them strong emotions
and often lead to charged relationships between patients and their
health providers and, by extension, patients and health researchers.
Persons are both autonomous and relational and a purely cognitive
model of autonomy neglects the social and relational basis of chronic
illness. Ensuring genuine informed consent in research requires a
thorough understanding of how participants perceive a study and
their reasons for participation. Surveys may not capture the
complexities of reasoning that underlies study participation.
Contradictory reasons for participation, for instance an initial claim
of altruism as rationale and a subsequent claim of personal benefit
(therapeutic misconception), affect the quality of informed consent.
Individuals apply principles through the filter of personal values and
lived experience. Authentic autonomy, and hence authentic consent
to research, occurs within the context of patients- unique life
narratives and illness experiences.
Abstract: In Korea, the technology of a load fo nuclear power plant has been being developed.
automatic controller which is able to control temperature and axial power distribution was developed. identification algorithm and a model predictive contact former transforms the nuclear reactor status into
numerically. And the latter uses them and ge
manipulated values such as two kinds of control ro
this automatic controller, the performance of a coperation was evaluated. As a result, the automatic generated model parameters of a nuclear react to nuclear reactor average temperature and axial power the desired targets during a daily load follow.
Abstract: The flash memory has many advantages such as low power consumption, strong shock resistance, fast I/O and non-volatility. And it is increasingly used in the mobile storage device. The YAFFS, one of the NAND flash file system, is widely used in the embedded device. However, the existing YAFFS takes long time to mount the file system because it scans whole spare areas in all pages of NAND flash memory. In order to solve this problem, we propose a new content-based flash file system using a mounting time reduction technique. The proposed method only scans partial spare areas of some special pages by using content-based block management. The experimental results show that the proposed method reduces the average mounting time by 87.2% comparing with JFFS2 and 69.9% comparing with YAFFS.