Abstract: Recently, there has been a considerable increase in the
number of procedures carried out under regional anesthesia.
However, percutaneous nephrolithotomy (PCNL) procedures are
usually performed under general anesthesia. The aim of this study
was to assess the safety and efficacy of PCNL under spinal anesthesia
in patients with renal calculi. We describe our 9 years experience of
performing PCNL under spinal anesthesia for 387 patients with large
stones of the upper urinary tract, with regard to the effectiveness and
side effects. All patients received spinal anesthetics (Lidocain 5%, or
Bupivacaine 0.75%) and underwent PCNL in prone position. The
success rate was 94.1%. The incidence of complications was 11.6%.
PCNL under spinal anesthesia is feasible, safe, and well-tolerated in
management of patients with renal stones.
Abstract: We prove detailed analysis of a waveguide-based Schottky barrier photodetector (SBPD) where a thin silicide film is put on the top of a silicon-on-insulator (SOI) channel waveguide to absorb light propagating along the waveguide. Taking both the confinement factor of light absorption and the wall scanning induced gain of the photoexcited carriers into account, an optimized silicide thickness is extracted to maximize the effective gain, thereby the responsivity. For typical lengths of the thin silicide film (10-20 Ðçm), the optimized thickness is estimated to be in the range of 1-2 nm, and only about 50-80% light power is absorbed to reach the maximum responsivity. Resonant waveguide-based SBPDs are proposed, which consist of a microloop, microdisc, or microring waveguide structure to allow light multiply propagating along the circular Si waveguide beneath the thin silicide film. Simulation results suggest that such resonant waveguide-based SBPDs have much higher repsonsivity at the resonant wavelengths as compared to the straight waveguidebased detectors. Some experimental results about Si waveguide-based SBPD are also reported.
Abstract: In the present study, the effect of ferrous sulfate concentration and total solids on bioleaching of heavy metals from sewage sludge has been examined using indigenous iron-oxidizing microorganisms. The experiments on effects of ferrous sulfate concentrations on bioleaching were carried out using ferrous sulfate of different concentrations (5-20 g L-1) to optimize the concentration of ferrous sulfate for maximum bioleaching. A rapid change in the pH and ORP took place in first 2 days followed by a slow change till 16th day in all the sludge samples. A 10 g L-1 ferrous sulfate concentration was found to be sufficient in metal bioleaching in the following order: Zn: 69%>Cu: 52%>Cr: 46%>Ni: 45. Further, bioleaching using 10 g/L ferrous sulfate was found to be efficient up to 20 g L-1 sludge solids concentration. The results of the present study strongly indicate that using 10 g L-1 ferrous sulfate indigenous iron-oxidizing microorganisms can bring down pH to a value needed for significant metal solubilization.
Abstract: Oxidative stress is considered to be the cause for onset
and the progression of type 2 diabetes mellitus (T2DM) and
complications including neuropathy. It is a deleterious process that
can be an important mediator of damage to cell structures: protein,
lipids and DNA. Data suggest that in patients with diabetes and
diabetic neuropathy DNA repair is impaired, which prevents effective
removal of lesions. Objective: The aim of our study was to evaluate
the association of the hOGG1 (326 Ser/Cys) and XRCC1 (194
Arg/Trp, 399 Arg/Gln) gene polymorphisms whose protein is
involved in the BER pathway with DNA repair efficiency in patients
with diabetes type 2 and diabetic neuropathy compared to the healthy
subjects. Genotypes were determined by PCR-RFLP analysis in 385
subjects, including 117 with type 2 diabetes, 56 with diabetic
neuropathy and 212 with normal glucose metabolism. The
polymorphisms studied include codon 326 of hOGG1 and 194, 399
of XRCC1 in the base excision repair (BER) genes. Comet assay was
carried out using peripheral blood lymphocytes from the patients and
controls. This test enabled the evaluation of DNA damage in cells
exposed to hydrogen peroxide alone and in the combination with the
endonuclease III (Nth). The results of the analysis of polymorphism
were statistically examination by calculating the odds ratio (OR) and
their 95% confidence intervals (95% CI) using the ¤ç2-tests. Our data
indicate that patients with diabetes mellitus type 2 (including those
with neuropathy) had higher frequencies of the XRCC1 399Arg/Gln
polymorphism in homozygote (GG) (OR: 1.85 [95% CI: 1.07-3.22],
P=0.3) and also increased frequency of 399Gln (G) allele (OR: 1.38
[95% CI: 1.03-1.83], P=0.3). No relation to other polymorphisms
with increased risk of diabetes or diabetic neuropathy. In T2DM
patients complicated by neuropathy, there was less efficient repair of
oxidative DNA damage induced by hydrogen peroxide in both the
presence and absence of the Nth enzyme. The results of our study
suggest that the XRCC1 399 Arg/Gln polymorphism is a significant
risk factor of T2DM in Polish population. Obtained data suggest a
decreased efficiency of DNA repair in cells from patients with
diabetes and neuropathy may be associated with oxidative stress.
Additionally, patients with neuropathy are characterized by even
greater sensitivity to oxidative damage than patients with diabetes,
which suggests participation of free radicals in the pathogenesis of
neuropathy.
Abstract: This paper describes a proposed support system which
enables applications designers to effectively create VR applications
using multiple haptic APIs. When the VR designers create
applications, it is often difficult to handle and understand many
parameters and functions that have to be set in the application program
using documentation manuals only. This complication may disrupt
creative imagination and result in inefficient coding. So, we proposed
the support application which improved the efficiency of VR
applications development and provided the interactive components of
confirmation of operations with haptic sense previously.
In this paper, we describe improvements of our former proposed
support application, which was applicable to multiple APIs and haptic
devices, and evaluate the new application by having participants
complete VR program. Results from a preliminary experiment suggest
that our application facilitates creation of VR applications.
Abstract: The clinical usefulness of heart rate variability is
limited to the range of Holter monitoring software available. These
software algorithms require a normal sinus rhythm to accurately
acquire heart rate variability (HRV) measures in the frequency
domain. Premature ventricular contractions (PVC) or more
commonly referred to as ectopic beats, frequent in heart failure,
hinder this analysis and introduce ambiguity. This investigation
demonstrates an algorithm to automatically detect ectopic beats by
analyzing discrete wavelet transform coefficients. Two techniques
for filtering and replacing the ectopic beats from the RR signal are
compared. One technique applies wavelet hard thresholding
techniques and another applies linear interpolation to replace ectopic
cycles. The results demonstrate through simulation, and signals
acquired from a 24hr ambulatory recorder, that these techniques can
accurately detect PVC-s and remove the noise and leakage effects
produced by ectopic cycles retaining smooth spectra with the
minimum of error.
Abstract: The study investigated the effects of Teaching Games
for Understanding approach on students ‘cognitive learning outcome.
The study was a quasi-experimental non-equivalent pretest-posttest
control group design whereby 10 year old primary school students
(n=72) were randomly assigned to an experimental and a control
group. The experimental group students were exposed with TGfU
approach and the control group with the Traditional Skill approach of
handball game. Game Performance Assessment Instrument (GPAI)
was used to measure students' tactical understanding and decision
making in 3 versus 3 handball game situations. Analysis of
covariance (ANCOVA) was used to analyze the data. The results
reveal that there was a significant difference between the TGfU
approach group and the traditional skill approach group students on
post test score (F (1, 69) = 248.83, p < .05). The findings of this
study suggested the importance of TGfU approach to improve
primary students’ tactical understanding and decision making in
handball game.
Abstract: Yeast cells live in a constantly changing environment that requires the continuous adaptation of their genomic program in order to sustain their homeostasis, survive and proliferate. Due to the advancement of high throughput technologies, there is currently a large amount of data such as gene expression, gene deletion and protein-protein interactions for S. Cerevisiae under various environmental conditions. Mining these datasets requires efficient computational methods capable of integrating different types of data, identifying inter-relations between different components and inferring functional groups or 'modules' that shape intracellular processes. This study uses computational methods to delineate some of the mechanisms used by yeast cells to respond to environmental changes. The GRAM algorithm is first used to integrate gene expression data and ChIP-chip data in order to find modules of coexpressed and co-regulated genes as well as the transcription factors (TFs) that regulate these modules. Since transcription factors are themselves transcriptionally regulated, a three-layer regulatory cascade consisting of the TF-regulators, the TFs and the regulated modules is subsequently considered. This three-layer cascade is then modeled quantitatively using artificial neural networks (ANNs) where the input layer corresponds to the expression of the up-stream transcription factors (TF-regulators) and the output layer corresponds to the expression of genes within each module. This work shows that (a) the expression of at least 33 genes over time and for different stress conditions is well predicted by the expression of the top layer transcription factors, including cases in which the effect of up-stream regulators is shifted in time and (b) identifies at least 6 novel regulatory interactions that were not previously associated with stress-induced changes in gene expression. These findings suggest that the combination of gene expression and protein-DNA interaction data with artificial neural networks can successfully model biological pathways and capture quantitative dependencies between distant regulators and downstream genes.
Abstract: Cement, the most widely used construction material
is very brittle and characterized by low tensile strength and strain
capacity. Macro to nano fibers are added to cement to provide
tensile strength and ductility to it. Carbon Nanotube (CNT), one of
the nanofibers, has proven to be a promising reinforcing material in
the cement composites because of its outstanding mechanical
properties and its ability to close cracks at the nano level. The
experimental investigations for CNT reinforced cement is costly,
time consuming and involves huge number of trials. Mathematical
modeling of CNT reinforced cement can be done effectively and
efficiently to arrive at the mechanical properties and to reduce the
number of trials in the experiments. Hence, an attempt is made to
numerically study the effective mechanical properties of CNT
reinforced cement numerically using Representative Volume
Element (RVE) method. The enhancement in its mechanical
properties for different percentage of CNTs is studied in detail.
Abstract: In blended learning environments, the Internet can be combined with other technologies. The aim of this research was to design, introduce and validate a model to support synchronous and asynchronous activities by managing content domains in an Adaptive Hypermedia System (AHS). The application is based on information recovery techniques, clustering algorithms and adaptation rules to adjust the user's model to contents and objects of study. This system was applied to blended learning in higher education. The research strategy used was the case study method. Empirical studies were carried out on courses at two universities to validate the model. The results of this research show that the model had a positive effect on the learning process. The students indicated that the synchronous and asynchronous scenario is a good option, as it involves a combination of work with the lecturer and the AHS. In addition, they gave positive ratings to the system and stated that the contents were adapted to each user profile.
Abstract: In the present work, study of the vibration of thin cylindrical shells made of a functionally gradient material (FGM) composed of stainless steel and nickel is presented. Material properties are graded in the thickness direction of the shell according to volume fraction power law distribution. The objective is to study the natural frequencies, the influence of constituent volume fractions and the effects of boundary conditions on the natural frequencies of the FG cylindrical shell. The study is carried out using third order shear deformation shell theory. The analysis is carried out using Hamilton's principle. The governing equations of motion of FG cylindrical shells are derived based on shear deformation theory. Results are presented on the frequency characteristics, influence of constituent volume fractions and the effects of clamped-free boundary conditions
Abstract: There are a number of different cars for transferring hundreds of close contacts of swine influenza patients to hospital, and we need to carefully assign the passengers to those cars in order to minimize the risk of influenza spreading during transportation. The paper presents an approach to straightforward obtain the optimal solution of the relaxed problems, and develops two iterative improvement algorithms to effectively tackle the general problem.
Abstract: The overall objective of this research is a strain
improvement technology for efficient pectinase production. A novel
cells cultivation technology by immobilization of fungal cells has
been studied in long time continuous fermentations. Immobilization
was achieved by using of new material for absorption of stores of
immobilized cultures which was for the first time used for
immobilization of microorganisms. Effects of various conditions of
nitrogen and carbon nutrition on the biosynthesis of pectolytic
enzymes in Aspergillus awamori 1-8 strain were studied. Proposed
cultivation technology along with optimization of media components
for pectinase overproduction led to increased pectinase productivity
in Aspergillus awamori 1-8 from 7 to 8 times. Proposed technology
can be applied successfully for production of major industrial
enzymes such as α-amylase, protease, collagenase etc.
Abstract: Biometric measures of one kind or another have been
used to identify people since ancient times, with handwritten
signatures, facial features, and fingerprints being the traditional
methods. Of late, Systems have been built that automate the task of
recognition, using these methods and newer ones, such as hand
geometry, voiceprints and iris patterns. These systems have different
strengths and weaknesses. This work is a two-section composition. In
the starting section, we present an analytical and comparative study
of common biometric techniques. The performance of each of them
has been viewed and then tabularized as a result. The latter section
involves the actual implementation of the techniques under
consideration that has been done using a state of the art tool called,
MATLAB. This tool aids to effectively portray the corresponding
results and effects.
Abstract: This study explored the relationship between
occupational stress and the perceived effectiveness of men and
women managers in Ghanaian organizations. The exploration is
underlined by attempt to understand the degree to which male and
female managers in Ghanaian organizations experience occupational
stress at the workplace. The purpose is to examine the sources and
extents of occupational stress experienced by male and female
managers in Ghana. Data was collected using questionnaires and
analyzed using both descriptive statistics and correlation analysis.
The results showed that female managers in Ghana are more likely to
report of more stress experiences in the workplace than their male
counterparts. The female managers are more likely to perceive role
conflict and alienation as job stressors while the male managers
perceived blocked career as a major source of workplace stress. It is
concluded that despite the female managers experiencing enormous
level of occupational stress, there was no significant differences
between their managerial effectiveness and that of the male.
Abstract: The purpose of this study is to investigate the effects
of modality principles in instructional software among first grade
pupils- achievements in the learning of Arabic Language. Two modes
of instructional software were systematically designed and
developed, audio with images (AI), and text with images (TI). The
quasi-experimental design was used in the study. The sample
consisted of 123 male and female pupils from IRBED Education
Directorate, Jordan. The pupils were randomly assigned to any one of
the two modes. The independent variable comprised the two modes
of the instructional software, the students- achievement levels in the
Arabic Language class and gender. The dependent variable was the
achievements of the pupils in the Arabic Language test. The
theoretical framework of this study was based on Mayer-s Cognitive
Theory of Multimedia Learning. Four hypotheses were postulated
and tested. Analyses of Variance (ANOVA) showed that pupils using
the (AI) mode performed significantly better than those using (TI)
mode. This study concluded that the audio with images mode was an
important aid to learning as compared to text with images mode.
Abstract: This article considers the positional buckling of
composite thick plates under thermal loading . For this purpose , the
complex finite strip method is used . In analysis of complex finite
strip, harmonic complex function in longitudinal direction , cubic
functions in transversal direction and parabola distribution of
transverse shear strain in thickness of thick plate based on higherorder
shear deformation theory are used . In given examples , the
effect of angles of stratification , number of layers , dimensions ratio
and length – to – thick ratio across critical temperature are
considered.
Abstract: The purpose of present paper was to investigate
perceptions of Korean secondary school students about social issues
related to biological sciences. Twenty issues were selected based on
topics of articles in the newspaper from 2005 to 2010. The issues were
categorized into biotechnology, health-disease and environment
domains. Subjects were 541 high school students (male 253 and
female 288). On the survey, students were asked to answer on 5-point
Lickert scales how they thought of the effect of biological phenomena
or events related to biological issues on the individual life and the
society. They perceived that the biological issues would be more
effectible on the society than on the individual life. Female students
had a little more perceptions than males.
Abstract: This work is devoted to the calculation of the
undulatory parameters and the study of the influence thickness of
electrical sheet on overvoltage compared to the carcass and between
whorls (sections) of the asynchronous motors supplied with PWM
converters.
Abstract: A given polynomial, possibly with multiple roots, is
factored into several lower-degree distinct-root polynomials with
natural-order-integer powers. All the roots, including multiplicities,
of the original polynomial may be obtained by solving these lowerdegree
distinct-root polynomials, instead of the original high-degree
multiple-root polynomial directly.
The approach requires polynomial Greatest Common Divisor
(GCD) computation. The very simple and effective process, “Monic
polynomial subtractions" converted trickily from “Longhand
polynomial divisions" of Euclidean algorithm is employed. It
requires only simple elementary arithmetic operations without any
advanced mathematics.
Amazingly, the derived routine gives the expected results for the
test polynomials of very high degree, such as p( x) =(x+1)1000.