Abstract: Proteomics is one of the largest areas of research for
bioinformatics and medical science. An ambitious goal of proteomics
is to elucidate the structure, interactions and functions of all proteins
within cells and organisms. Predicting Protein-Protein Interaction
(PPI) is one of the crucial and decisive problems in current research.
Genomic data offer a great opportunity and at the same time a lot of
challenges for the identification of these interactions. Many methods
have already been proposed in this regard. In case of in-silico
identification, most of the methods require both positive and negative
examples of protein interaction and the perfection of these examples
are very much crucial for the final prediction accuracy. Positive
examples are relatively easy to obtain from well known databases. But
the generation of negative examples is not a trivial task. Current PPI
identification methods generate negative examples based on some
assumptions, which are likely to affect their prediction accuracy.
Hence, if more reliable negative examples are used, the PPI prediction
methods may achieve even more accuracy. Focusing on this issue, a
graph based negative example generation method is proposed, which
is simple and more accurate than the existing approaches. An
interaction graph of the protein sequences is created. The basic
assumption is that the longer the shortest path between two
protein-sequences in the interaction graph, the less is the possibility of
their interaction. A well established PPI detection algorithm is
employed with our negative examples and in most cases it increases
the accuracy more than 10% in comparison with the negative pair
selection method in that paper.
Abstract: Technology transfer of renewable energy technologies is very often unsuccessful in the developing world. Aside from challenges that have social, economic, financial, institutional and environmental dimensions, technology transfer has generally been misunderstood, and largely seen as mere delivery of high tech equipment from developed to developing countries or within the developing world from R&D institutions to society. Technology transfer entails much more, including, but not limited to: entire systems and their component parts, know-how, goods and services, equipment, and organisational and managerial procedures. Means to facilitate the successful transfer of energy technologies, including the sharing of lessons are subsequently extremely important for developing countries as they grapple with increasing energy needs to sustain adequate economic growth and development. Improving the success of technology transfer is an ongoing process as more projects are implemented, new problems are encountered and new lessons are learnt. Renewable energy is also critical to improve the quality of lives of the majority of people in developing countries. In rural areas energy is primarily traditional biomass. The consumption activities typically occur in an inefficient manner, thus working against the notion of sustainable development. This paper explores the implementation of technology transfer in the developing world (sub-Saharan Africa). The focus is necessarily on RETs since most rural energy initiatives are RETs-based. Additionally, it aims to highlight some lessons drawn from the cited RE projects and identifies notable differences where energy technology transfer was judged to be successful. This is done through a literature review based on a selection of documented case studies which are judged against the definition provided for technology transfer. This paper also puts forth research recommendations that might contribute to improved technology transfer in the developing world. Key findings of this paper include: Technology transfer cannot be complete without satisfying pre-conditions such as: affordability, maintenance (and associated plans), knowledge and skills transfer, appropriate know how, ownership and commitment, ability to adapt technology, sound business principles such as financial viability and sustainability, project management, relevance and many others. It is also shown that lessons are learnt in both successful and unsuccessful projects.
Abstract: Master plan is a tool to guide and manage the growth of cities in a planned manner. The soul of a master plan lies in its implementation framework. If not implemented, people are trapped in a mess of urban problems and laissez-faire development having serious long term repercussions. Unfortunately, Master Plans prepared for several major cities of Pakistan could not be fully implemented due to host of reasons and Lahore is no exception. Being the second largest city of Pakistan with a population of over 7 million people, Lahore holds the distinction that the first ever Master Plan in the country was prepared for this city in 1966. Recently in 2004, a new plan titled `Integrated Master Plan for Lahore-2021- has been approved for implementation. This paper provides a comprehensive account of the weaknesses and constraints in the plan preparation process and implementation strategies of Master Plans prepared for Lahore. It also critically reviews the new Master Plan particularly with respect to the proposed implementation framework. The paper discusses the prospects and pre-conditions for successful implementation of the new Plan in the light of historic analysis, interviews with stakeholders and the new institutional context under the devolution plan.
Abstract: Rapid steps made in the field of Information and Communication Technology (ICT) has facilitated the development of teaching and learning methods and prepared them to serve the needs of an assorted educational institution. In other words, the information age has redefined the fundamentals and transformed the institutions and method of services delivery forever. The vision is the articulation of a desire to transform the method of teaching and learning could proceed through e-learning. E-learning is commonly deliberated to use of networked information and communications technology in teaching and learning practice. This paper deals the general aspects of the e-leaning with its issues, developments, opportunities and challenges, which can the higher institutions own.
Abstract: The evaluation of conversational agents or chatterbots question answering systems is a major research area that needs much attention. Before the rise of domain-oriented conversational agents based on natural language understanding and reasoning, evaluation is never a problem as information retrieval-based metrics are readily available for use. However, when chatterbots began to become more domain specific, evaluation becomes a real issue. This is especially true when understanding and reasoning is required to cater for a wider variety of questions and at the same time to achieve high quality responses. This paper discusses the inappropriateness of the existing measures for response quality evaluation and the call for new standard measures and related considerations are brought forward. As a short-term solution for evaluating response quality of conversational agents, and to demonstrate the challenges in evaluating systems of different nature, this research proposes a blackbox approach using observation, classification scheme and a scoring mechanism to assess and rank three example systems, AnswerBus, START and AINI.
Abstract: In Data mining, Fuzzy clustering algorithms have
demonstrated advantage over crisp clustering algorithms in dealing
with the challenges posed by large collections of vague and uncertain
natural data. This paper reviews concept of fuzzy logic and fuzzy
clustering. The classical fuzzy c-means algorithm is presented and its
limitations are highlighted. Based on the study of the fuzzy c-means
algorithm and its extensions, we propose a modification to the cmeans
algorithm to overcome the limitations of it in calculating the
new cluster centers and in finding the membership values with
natural data. The efficiency of the new modified method is
demonstrated on real data collected for Bhutan-s Gross National
Happiness (GNH) program.
Abstract: As a result of the ever-changing environment and the demands of rganisations- customers, it is important to recognise the importance of some important managerial challenges. It is the sincere belief that failure to meet these challenges, will ultimately contribute to inevitable problems for organisations. This recognition
requires from managers and by implication organisations to be engaged in ethical behaviour, identity awareness and learning organisational behaviour. All these aspects actually reflect on the
importance of intellectual capital as the competitive weapons for
organisations in the future.
Abstract: Information society is an absolutely new public formation at which the infrastructure and the social relations correspond to the socialized essence of «information genotype» mankind. Information society is a natural social environment which allows the person to open completely the information nature, to use intelligence for joint creation with other people of new information on the basis of knowledge earlier saved up by previous generations.
Abstract: Random and natural textures classification is still
one of the biggest challenges in the field of image processing and
pattern recognition. In this paper, texture feature extraction using
Slant Hadamard Transform was studied and compared to other
signal processing-based texture classification schemes. A
parametric SHT was also introduced and employed for natural
textures feature extraction. We showed that a subtly modified
parametric SHT can outperform ordinary Walsh-Hadamard
transform and discrete cosine transform. Experiments were carried
out on a subset of Vistex random natural texture images using a
kNN classifier.
Abstract: This paper challenges the relevance of knowledgebased
management research by arguing that the majority of the
literature emphasizes information and knowledge provision instead of
their business usage. For this reason the related processes are
considered valuable and eligible as such, which has led to
overlapping nature of knowledge-based management disciplines. As
a solution, this paper turns the focus on the information usage. Value
of knowledge and respective management tasks are then defined by
the business need and the knowledge-user becomes the main actor.
The paper analyses the prevailing literature streams and recognizes
the need for a more focused and robust understanding of knowledgebased
value creation. The paper contributes by synthetizing the
existing literature and pinpointing the essence of knowledge-based
management disciplines.
Abstract: Although current competitive challenges induced by today-s digital economy place their main emphasis on organizational knowledge, customer knowledge has been overlooked. On the other hand, the business community has finally begun to realize the important role customer knowledge can play in the organizational boundaries of the corporate arena. As a result, there is an emerging market for the tools and utilities whose objective is to provide the intelligence for knowledge sharing between the businesses and their customers. In this paper, we present a conceptual model of customer knowledge management by identifying and analyzing the existing tools in the market. The focus will be upon the emerging British dotcom industry whose customer based B2C behavior has been an influential part of the knowledge based intelligence tools in existence today.
Abstract: Thermoacoustic instabilities in combustors have
remained a topic of investigation for over a few decades due to the
challenges it posses to the operation of low emission gas turbines.
For combustors burning liquid fuel, understanding the cause-andeffect
relationship between spray combustion dynamics and
thermoacoustic oscillations is imperative for the successful
development of any control methodology for its mitigation. The
paper presents some very unique operating characteristics of a
kerosene-fueled diffusion type combustor undergoing limit-cycle
oscillations. Combustor stability limits were mapped using three
different-sized injectors. The results show that combustor instability
depends on the characteristics of the fuel spray. A simple analytic
analysis is also reported in support of a plausible explanation for the
unique combustor behavior. The study indicates that high amplitude
acoustic pressure in the combustor may cause secondary breakdown
of fuel droplets resulting in premixed pre-vaporized type burning of
the diffusion type combustor.
Abstract: Developments in communication technologies
especially in wireless have enabled the progress of low-cost and lowpower
wireless sensor networks (WSNs). The features of such WSN
are holding minimal energy, weak computational capabilities,
wireless communication and an open-medium nature where sensors
are deployed. WSN is underpinned by application driven such as
military applications, the health sector, etc. Due to the intrinsic nature
of the network and application scenario, WSNs are vulnerable to
many attacks externally and internally. In this paper we have focused
on the types of internal attacks of WSNs based on OSI model and
discussed some security requirements, characterizers and challenges
of WSNs, by which to contribute to the WSN-s security research.
Abstract: This paper explores transformation of higher
education system in Kazakhstan since 1991. The research unravels
successful experience in the field and challenges. It covers issues of institutional change, faculty, research, university, funding, standards
and leadership. The paper offers recommendations in improving state of art in higher educational institutions of Kazakhstan based on
international approaches and local realities.
Abstract: The Philosophy of Sufficiency Economy, bestowed
by His Majesty the King Bhumibol Adulyadej to the people of
Thailand, highlights a balanced way of living. Three principles of
moderation reasonableness, and immunity, along with the conditions
for morality and knowledge, can be applied to any level of the
society–from an individual to the nation. The Philosophy of
Sufficiency Economy helps address the current development
challenges, which are issues on institutions, environmental
sustainability, human well-being, and the role of the government.
Abstract: The aspiration of this research article is to target and
focus the gains of university-Industry (U-I) collaborations and
exploring those hurdles which are the obstacles for attaining these
gains. University-Industry collaborations have attained great
importance since 1980 in USA due to its application in all fields of
life. U-I collaboration is a bilateral process where academia is a
proactive member to make such alliances. Universities want to
ameliorate their academic-base with the technicalities of technobabbles.
U-I collaboration is becoming an essential lane for achieving
innovative goals in this century. Many developed nations have set
successful examples to prove this phenomenon as a catalyst to reduce
costs, efforts and personnel for R&D projects. This study is exploits
amplitudes of UI collaboration incentives in the light of success
stories of developed countries. Many universities in USA, UK,
Canada and various European Countries have been engaged with
enterprises for numerous collaborative agreements. A long list of
strategic and short term R&D projects has been executed in
developed countries to accomplish their intended purposes. Due to
the lack of intentions, genuine research and research-oriented
environment, the mentioned field could not grow very well in
developing countries. During last decade, a new wave of research
has induced the institutes of developing countries to promote R&D
culture especially in Pakistan. Higher Education Commission (HEC)
has initiated many projects and funding supports for universities
which have collaborative intentions with industry.
Findings show that rapid innovation, overwhelm the technological
complexities and articulated intellectual-base are major incentives
which steer both partners to establish faculty-industry alliances. Everchanging
technologies, concerned about intellectual property,
different research environment and culture, research relevancy (Basic
or applied), exposure differences and diversity of knowledge
(bookish or practical) are main barriers to establish and retain joint
ventures. Findings also concluded that, it is dire need to support and
enhance cooperation among academia and industry to promote highly
coordinated research behaviors. Author has proposed a roadmap for
developing countries to promote R&D clusters among faculty and
industry to deal the technological challenges and innovation
complexities. Based on our research findings, Model for R&D
Collaboration for developing countries also have been proposed to
promote articulated R&D environment. If developing countries
follow this phenomenon, rapid innovations can be achieved with
limited R&D budget heads.
Abstract: One of the major challenges in the Information
Retrieval field is handling the massive amount of information
available to Internet users. Existing ranking techniques and strategies
that govern the retrieval process fall short of expected accuracy.
Often relevant documents are buried deep in the list of documents
returned by the search engine. In order to improve retrieval accuracy
we examine the issue of language effect on the retrieval process.
Then, we propose a solution for a more biased, user-centric relevance
for retrieved data. The results demonstrate that using indices based
on variations of the same language enhances the accuracy of search
engines for individual users.
Abstract: Development of knowledge based society carries multiple challenges to the higher education system. Some of the challenges laid before the higher education sector of countries which aspire to become knowledge based societies are: the entrepreneurial leadership of the higher education institutions, finding new sources of financing in order to minimize dependence on public resources, creating connections with the labor market, commercial utilization of R&D results, promotion of innovations as well as the overall promotion of science excellence relevant to the economic sector. Within a framework of this paper and its main subject of research, the challenge which is being put before the higher education institutions is an effort of establishing regional mission of higher education through the open collaboration with regional key factors, both private and public. Development of the mentioned collaboration and its contribution to the overall regional development in Croatia is the main subject of empirical research in this paper.
Abstract: Manufacturing companies are facing a broad variety
of challenges caused by a dynamic production environment. To
succeed in such an environment, it is crucial to minimize the loss of
time required to trigger the adaptation process of a company-s
production structures. This paper presents an approach for the
continuous monitoring of production structures by neurologic
principles. It enhances classical monitoring concepts, which are
principally focused on reactive strategies, and enables companies to
act proactively. Thereby, strategic aspects regarding the
harmonization of certain life cycles are integrated into the decision
making process for triggering the reconfiguration process of the
production structure.
Abstract: Internet application in China has maintained a constant
development tendency in the past decade. China is now one of the
most populous countries in terms of internet user population. While
offering enormous opportunities, the dramatic digitalization also
brings about a series of challenges that demand urgent attention.
Digital divide is one of the challenges that affect China as well as other
countries in the world. This paper examines digital divide in the
Chinese context from the perspective of development communication.
Through a case study of a rural township under the backdrop of the
rapid internet development in China, the paper discusses the
economic, psychological and cultural roots of digital divide; and
explores development communication strategies addressing the roots
of digital divide. It is argued that development communication must be
responsive to the potentialities and preferences of the specific society
and serve the purposes of participation and sustainability.