Abstract: A systems approach model for prostate cancer in prostate duct, as a sub-system of the organism is developed. It is accomplished in two steps. First this research work starts with a nonlinear system of coupled Fokker-Plank equations which models continuous process of the system like motion of cells. Then extended to PDEs that include discontinuous processes like cell mutations, proliferation and deaths. The discontinuous processes is modeled by using intensity poisson processes. The model incorporates the features of the prostate duct. The system of PDEs spatial coordinate is along the proximal distal axis. Its parameters depend on features of the prostate duct. The movement of cells is biased towards distal region and mutations of prostate cancer cells is localized in the proximal region. Numerical solutions of the full system of equations are provided, and are exhibit traveling wave fronts phenomena. This motivates the use of the standard transformation to derive a canonically related system of ODEs for traveling wave solutions. The results obtained show persistence of prostate cancer by showing that the non-negative cone for the traveling wave system is time invariant. The traveling waves have a unique global attractor is proved also. Biologically, the global attractor verifies that evolution of prostate cancer stem cells exhibit the avascular tumor growth. These numerical solutions show that altering prostate stem cell movement or mutation of prostate cancer cells lead to avascular tumor. Conclusion with comments on clinical implications of the model is discussed.
Abstract: e-Government structures permits the government to operate in a more transparent and accountable manner of which it increases the power of the individual in relation to that of the government. This paper identifies the factors that determine customer-s attitude towards e-Government services using a theoretical model based on the Technology Acceptance Model. Data relating to the constructs were collected from 200 respondents. The research model was tested using Structural Equation Modeling (SEM) techniques via the Analysis of Moment Structure (AMOS 16) computer software. SEM is a comprehensive approach to testing hypotheses about relations among observed and latent variables. The proposed model fits the data well. The results demonstrated that e- Government services acceptance can be explained in terms of compatibility and attitude towards e-Government services. The setup of the e-Government services will be compatible with the way users work and are more likely to adopt e-Government services owing to their familiarity with the Internet for various official, personal, and recreational uses. In addition, managerial implications for government policy makers, government agencies, and system developers are also discussed.
Abstract: By means of the extended homoclinic test approach (shortly EHTA) with the aid of a symbolic computation system such as Maple, some complexiton type solutions for the (3+1)-dimensional Jimbo-Miwa equation are presented.
Abstract: We present a new intuitionistic fuzzy aggregation
operator called the intuitionistic fuzzy ordered weighted
averaging-weighted average (IFOWAWA) operator. The main
advantage of the IFOWAWA operator is that it unifies the OWA
operator with the WA in the same formulation considering the degree
of importance that each concept has in the aggregation. Moreover, it is
able to deal with an uncertain environment that can be assessed with
intuitionistic fuzzy numbers. We study some of its main properties and
we see that it has a lot of particular cases such as the intuitionistic
fuzzy weighted average (IFWA) and the intuitionistic fuzzy OWA
(IFOWA) operator. Finally, we study the applicability of the new
approach on a financial decision making problem concerning the
selection of financial strategies.
Abstract: The Internet is the global data communications
infrastructure based on the interconnection of both public and private
networks using protocols that implement Internetworking on a global
scale. Hence the control of protocol and infrastructure development,
resource allocation and network operation are crucial and interlinked
aspects. Internet Governance is the hotly debated and contentious
subject that refers to the global control and operation of key Internet
infrastructure such as domain name servers and resources such as
domain names. It is impossible to separate technical and political
positions as they are interlinked. Furthermore the existence of a
global market, transparency and competition impact upon Internet
Governance and related topics such as network neutrality and
security. Current trends and developments regarding Internet
governance with a focus on the policy-making process, security and
control have been observed to evaluate current and future
implications on the Internet. The multi stakeholder approach to
Internet Governance discussed in this paper presents a number of
opportunities, issues and developments that will affect the future
direction of the Internet. Internet operation, maintenance and
advisory organisations such as the Internet Corporation for Assigned
Names and Numbers (ICANN) or the Internet Governance Forum
(IGF) are currently in the process of formulating policies for future
Internet Governance. Given the controversial nature of the issues at
stake and the current lack of agreement it is predicted that
institutional as well as market governance will remain present for the
network access and content.
Abstract: The POD-assisted projective integration method based on the equation-free framework is presented in this paper. The method is essentially based on the slow manifold governing of given system. We have applied two variants which are the “on-line" and “off-line" methods for solving the one-dimensional viscous Bergers- equation. For the on-line method, we have computed the slow manifold by extracting the POD modes and used them on-the-fly along the projective integration process without assuming knowledge of the underlying slow manifold. In contrast, the underlying slow manifold must be computed prior to the projective integration process for the off-line method. The projective step is performed by the forward Euler method. Numerical experiments show that for the case of nonperiodic system, the on-line method is more efficient than the off-line method. Besides, the online approach is more realistic when apply the POD-assisted projective integration method to solve any systems. The critical value of the projective time step which directly limits the efficiency of both methods is also shown.
Abstract: In this paper electrical characteristics of various kinds
of multiple-gate silicon nanowire transistors (SNWT) with the
channel length equal to 7 nm are compared. A fully ballistic quantum
mechanical transport approach based on NEGF was employed to
analyses electrical characteristics of rectangular and cylindrical
silicon nanowire transistors as well as a Double gate MOS FET. A
double gate, triple gate, and gate all around nano wires were studied
to investigate the impact of increasing the number of gates on the
control of the short channel effect which is important in nanoscale
devices. Also in the case of triple gate rectangular SNWT inserting
extra gates on the bottom of device can improve the application of
device. The results indicate that by using gate all around structures
short channel effects such as DIBL, subthreshold swing and delay
reduces.
Abstract: This study demonstrates the use of Class F fly ash in
combination with lime or lime kiln dust in the full depth reclamation
(FDR) of asphalt pavements. FDR, in the context of this paper, is a
process of pulverizing a predetermined amount of flexible pavement
that is structurally deficient, blending it with chemical additives and
water, and compacting it in place to construct a new stabilized base
course. Test sections of two structurally deficient asphalt pavements
were reclaimed using Class F fly ash in combination with lime and
lime kiln dust. In addition, control sections were constructed using
cement, cement and emulsion, lime kiln dust and emulsion, and mill
and fill. The service performance and structural behavior of the FDR
pavement test sections were monitored to determine how the fly ash
sections compared to other more traditional pavement rehabilitation
techniques. Service performance and structural behavior were
determined with the use of sensors embedded in the road and Falling
Weight Deflectometer (FWD) tests. Monitoring results of the FWD
tests conducted up to 2 years after reclamation show that the cement,
fly ash+LKD, and fly ash+lime sections exhibited two year resilient
modulus values comparable to open graded cement stabilized
aggregates (more than 750 ksi). The cement treatment resulted in a
significant increase in resilient modulus within 3 weeks of
construction and beyond this curing time, the stiffness increase was
slow. On the other hand, the fly ash+LKD and fly ash+lime test
sections indicated slower shorter-term increase in stiffness. The fly
ash+LKD and fly ash+lime section average resilient modulus values
at two years after construction were in excess of 800 ksi. Additional
longer-term testing data will be available from ongoing pavement
performance and environmental condition data collection at the two
pavement sites.
Abstract: Freeways are originally designed to provide high
mobility to road users. However, the increase in population and
vehicle numbers has led to increasing congestions around the world.
Daily recurrent congestion substantially reduces the freeway capacity
when it is most needed. Building new highways and expanding the
existing ones is an expensive solution and impractical in many
situations. Intelligent and vision-based techniques can, however, be
efficient tools in monitoring highways and increasing the capacity of
the existing infrastructures. The crucial step for highway monitoring
is vehicle detection. In this paper, we propose one of such
techniques. The approach is based on artificial neural networks
(ANN) for vehicles detection and counting. The detection process
uses the freeway video images and starts by automatically extracting
the image background from the successive video frames. Once the
background is identified, subsequent frames are used to detect
moving objects through image subtraction. The result is segmented
using Sobel operator for edge detection. The ANN is, then, used in
the detection and counting phase. Applying this technique to the
busiest freeway in Riyadh (King Fahd Road) achieved higher than
98% detection accuracy despite the light intensity changes, the
occlusion situations, and shadows.
Abstract: Many difficulties are faced in the process of learning
computer programming. This paper will propose a system framework
intended to reduce cognitive load in learning programming. In first
section focus is given on the process of learning and the
shortcomings of the current approaches to learning programming.
Finally the proposed prototype is suggested along with the
justification of the prototype. In the proposed prototype the concept
map is used as visualization metaphor. Concept maps are similar to
the mental schema in long term memory and hence it can reduce
cognitive load well. In addition other method such as part code
method is also proposed in this framework to can reduce cognitive
load.
Abstract: Cancers could normally be marked by a number of
differentially expressed genes which show enormous potential as
biomarkers for a certain disease. Recent years, cancer classification
based on the investigation of gene expression profiles derived by
high-throughput microarrays has widely been used. The selection of
discriminative genes is, therefore, an essential preprocess step in
carcinogenesis studies. In this paper, we have proposed a novel gene
selector using information-theoretic measures for biological
discovery. This multivariate filter is a four-stage framework through
the analyses of feature relevance, feature interdependence, feature
redundancy-dependence and subset rankings, and having been
examined on the colon cancer data set. Our experimental result show
that the proposed method outperformed other information theorem
based filters in all aspect of classification errors and classification
performance.
Abstract: The number of framework conceived for e-learning
constantly increase, unfortunately the creators of learning materials
and educational institutions engaged in e-formation adopt a
“proprietor" approach, where the developed products (courses,
activities, exercises, etc.) can be exploited only in the framework
where they were conceived, their uses in the other learning
environments requires a greedy adaptation in terms of time and
effort. Each one proposes courses whose organization, contents,
modes of interaction and presentations are unique for all learners,
unfortunately the latter are heterogeneous and are not interested by
the same information, but only by services or documents adapted to
their needs. Currently the new tendency for the framework
conceived for e-learning, is the interoperability of learning materials,
several standards exist (DCMI (Dublin Core Metadata Initiative)[2],
LOM (Learning Objects Meta data)[1], SCORM (Shareable Content
Object Reference Model)[6][7][8], ARIADNE (Alliance of Remote
Instructional Authoring and Distribution Networks for Europe)[9],
CANCORE (Canadian Core Learning Resource Metadata
Application Profiles)[3]), they converge all to the idea of learning
objects. They are also interested in the adaptation of the learning
materials according to the learners- profile. This article proposes an
approach for the composition of courses adapted to the various
profiles (knowledge, preferences, objectives) of learners, based on
two ontologies (domain to teach and educational) and the learning
objects.
Abstract: Many computational techniques were applied to
solution of heat conduction problem. Those techniques were the
finite difference (FD), finite element (FE) and recently meshless
methods. FE is commonly used in solution of equation of heat
conduction problem based on the summation of stiffness matrix of
elements and the solution of the final system of equations. Because
of summation process of finite element, convergence rate was
decreased. Hence in the present paper Cellular Automata (CA)
approach is presented for the solution of heat conduction problem.
Each cell considered as a fixed point in a regular grid lead to the
solution of a system of equations is substituted by discrete systems of
equations with small dimensions. Results show that CA can be used
for solution of heat conduction problem.
Abstract: This paper suggests an improved integer frequency
offset (IFO) estimation scheme using P1 symbol for orthogonal
frequency division multiplexing (OFDM) based the second generation
terrestrial digital video broadcasting (DVB-T2) system. Proposed
IFO estimator is designed by a low-complexity blind IFO estimation
scheme, which is implemented with complex additions. Also, we
propose active carriers (ACs) selection scheme in order to prevent
performance degradation in blind IFO estimation. The simulation
results show that under the AWGN and TU6 channels, the proposed
method has low complexity than conventional method and almost
similar performance in comparison with the conventional method.
Abstract: Evolutionary Algorithms are population-based,
stochastic search techniques, widely used as efficient global
optimizers. However, many real life optimization problems often
require finding optimal solution to complex high dimensional,
multimodal problems involving computationally very expensive
fitness function evaluations. Use of evolutionary algorithms in such
problem domains is thus practically prohibitive. An attractive
alternative is to build meta models or use an approximation of the
actual fitness functions to be evaluated. These meta models are order
of magnitude cheaper to evaluate compared to the actual function
evaluation. Many regression and interpolation tools are available to
build such meta models. This paper briefly discusses the
architectures and use of such meta-modeling tools in an evolutionary
optimization context. We further present two evolutionary algorithm
frameworks which involve use of meta models for fitness function
evaluation. The first framework, namely the Dynamic Approximate
Fitness based Hybrid EA (DAFHEA) model [14] reduces
computation time by controlled use of meta-models (in this case
approximate model generated by Support Vector Machine
regression) to partially replace the actual function evaluation by
approximate function evaluation. However, the underlying
assumption in DAFHEA is that the training samples for the metamodel
are generated from a single uniform model. This does not take
into account uncertain scenarios involving noisy fitness functions.
The second model, DAFHEA-II, an enhanced version of the original
DAFHEA framework, incorporates a multiple-model based learning
approach for the support vector machine approximator to handle
noisy functions [15]. Empirical results obtained by evaluating the
frameworks using several benchmark functions demonstrate their
efficiency
Abstract: The conjugate gradient optimization algorithm
usually used for nonlinear least squares is presented and is
combined with the modified back propagation algorithm yielding
a new fast training multilayer perceptron (MLP) algorithm
(CGFR/AG). The approaches presented in the paper consist of
three steps: (1) Modification on standard back propagation
algorithm by introducing gain variation term of the activation
function, (2) Calculating the gradient descent on error with
respect to the weights and gains values and (3) the determination
of the new search direction by exploiting the information
calculated by gradient descent in step (2) as well as the previous
search direction. The proposed method improved the training
efficiency of back propagation algorithm by adaptively modifying
the initial search direction. Performance of the proposed method
is demonstrated by comparing to the conjugate gradient algorithm
from neural network toolbox for the chosen benchmark. The
results show that the number of iterations required by the
proposed method to converge is less than 20% of what is required
by the standard conjugate gradient and neural network toolbox
algorithm.
Abstract: This paper begins with formal defining of human rights and freedoms, and the basic document regarding the said subject is undoubtedly French Declaration of the Rights of Man and of the Citizen from 789. This paper furthermore parses legal sources relevant for the workers' rights in legal system of the Republic of Croatia, international contracts and the Labour Act, which is also a master bill regarding workers' rights The authors are also dealing with issues of Constitutional Court of the Republic of Croatia and its' position in judicial system of the Republic of Croatia, as well as with the specifics of Constitutional Complaint, and the crucial part of the paper is based on the research conducted with an aim to determine implementation of rights and liberties guaranteed by the articles 54. and 55. of the Constitution of the Republic of Croatia by means of Constitutional Complaint.
Abstract: In this paper we present a method for gene ranking
from DNA microarray data. More precisely, we calculate the correlation
networks, which are unweighted and undirected graphs, from
microarray data of cervical cancer whereas each network represents
a tissue of a certain tumor stage and each node in the network
represents a gene. From these networks we extract one tree for
each gene by a local decomposition of the correlation network. The
interpretation of a tree is that it represents the n-nearest neighbor
genes on the n-th level of a tree, measured by the Dijkstra distance,
and, hence, gives the local embedding of a gene within the correlation
network. For the obtained trees we measure the pairwise similarity
between trees rooted by the same gene from normal to cancerous
tissues. This evaluates the modification of the tree topology due to
progression of the tumor. Finally, we rank the obtained similarity
values from all tissue comparisons and select the top ranked genes.
For these genes the local neighborhood in the correlation networks
changes most between normal and cancerous tissues. As a result
we find that the top ranked genes are candidates suspected to be
involved in tumor growth and, hence, indicates that our method
captures essential information from the underlying DNA microarray
data of cervical cancer.
Abstract: Environmental factors affect agriculture production
productivity and efficiency resulted in changing of profit efficiency.
This paper attempts to estimate the impacts of environmental factors
to profitability of rice farmers in the Red River Delta of Vietnam. The
dataset was extracted from 349 rice farmers using personal
interviews. Both OLS and MLE trans-log profit functions were used
in this study. Five production inputs and four environmental factors
were included in these functions. The estimation of the stochastic
profit frontier with a two-stage approach was used to measure
profitability. The results showed that the profit efficiency was about
75% on the average and environmental factors change profit
efficiency significantly beside farm specific characteristics. Plant
disease, soil fertility, irrigation apply and water pollution were the
four environmental factors cause profit loss in rice production. The
result indicated that farmers should reduce household size, farm
plots, apply row seeding technique and improve environmental
factors to obtain high profit efficiency with special consideration is
given for irrigation water quality improvement.
Abstract: A mobile agent is a software which performs an
action autonomously and independently as a person or an
organizations assistance. Mobile agents are used for searching
information, retrieval information, filtering, intruder recognition in
networks, and so on. One of the important issues of mobile agent is
their security. It must consider different security issues in effective
and secured usage of mobile agent. One of those issues is the
integrity-s protection of mobile agents.
In this paper, the advantages and disadvantages of each method,
after reviewing the existing methods, is examined. Regarding to this
matter that each method has its own advantage or disadvantage, it
seems that by combining these methods, one can reach to a better
method for protecting the integrity of mobile agents. Therefore, this
method is provided in this paper and then is evaluated in terms of
existing method. Finally, this method is simulated and its results are
the sign of improving the possibility of integrity-s protection of
mobile agents.