Abstract: The prediction of transmembrane helical segments
(TMHs) in membrane proteins is an important field in the
bioinformatics research. In this paper, a new method based on discrete
wavelet transform (DWT) has been developed to predict the number
and location of TMHs in membrane proteins. PDB coded as 1KQG
was chosen as an example to describe the prediction of the number and
location of TMHs in membrane proteins by using this method. To
access the effect of the method, 80 proteins with known 3D-structure
from Mptopo database are chosen at random as the test objects
(including 325 TMHs), 308 of which can be predicted accurately, the
average predicted accuracy is 96.3%. In addition, the above 80
membrane proteins are divided into 13 groups according to their
function and type. In particular, the results of the prediction of TMHs
of the 13 groups are satisfying.
Abstract: The paper deals with a mathematical model for fluid dynamic flows on road networks which is based on conservation laws. This nonlinear framework is based on the conservation of cars. We focus on traffic circle, which is a finite number of roads that meet at some junctions. The traffic circle with junctions having either one incoming and two outgoing or two incoming and one outgoing roads. We describe the numerical schemes with the particular boundary conditions used to produce approximated solutions of the problem.
Abstract: In this paper after reviewing some previous studies, in
order to optimize the above knee prosthesis, beside the inertial
properties a new controlling parameter is informed. This controlling
parameter makes the prosthesis able to act as a multi behavior system
when the amputee is opposing to different environments. This active
prosthesis with the new controlling parameter can simplify the
control of prosthesis and reduce the rate of energy consumption in
comparison to recently presented similar prosthesis “Agonistantagonist
active knee prosthesis".
In this paper three models are generated, a passive, an active, and
an optimized active prosthesis. Second order Taylor series is the
numerical method in solution of the models equations and the
optimization procedure is genetic algorithm.
Modeling the prosthesis which comprises this new controlling
parameter (SEP) during the swing phase represents acceptable results
in comparison to natural behavior of shank. Reported results in this
paper represent 3.3 degrees as the maximum deviation of models
shank angle from the natural pattern. The natural gait pattern belongs
to walking at the speed of 81 m/min.
Abstract: There is wide range of scientific workflow systems
today, each one designed to resolve problems at a specific level. In
large collaborative projects, it is often necessary to recognize the
heterogeneous workflow systems already in use by various partners
and any potential collaboration between these systems requires
workflow interoperability. Publish/Subscribe Scientific Workflow
Interoperability Framework (PS-SWIF) approach was proposed to
achieve workflow interoperability among workflow systems. This
paper evaluates the PS-SWIF approach and its system to achieve
workflow interoperability using Web Services with asynchronous
notification messages represented by WS-Eventing standard. This
experiment covers different types of communication models provided
by Workflow Management Coalition (WfMC). These models are:
Chained processes, Nested synchronous sub-processes, Event
synchronous sub-processes, and Nested sub-processes
(Polling/Deferred Synchronous). Also, this experiment shows the
flexibility and simplicity of the PS-SWIF approach when applied to a
variety of workflow systems (Triana, Taverna, Kepler) in local and
remote environments.
Abstract: In large datasets, identifying exceptional or rare cases
with respect to a group of similar cases is considered very significant
problem. The traditional problem (Outlier Mining) is to find
exception or rare cases in a dataset irrespective of the class label of
these cases, they are considered rare events with respect to the whole
dataset. In this research, we pose the problem that is Class Outliers
Mining and a method to find out those outliers. The general
definition of this problem is “given a set of observations with class
labels, find those that arouse suspicions, taking into account the
class labels". We introduce a novel definition of Outlier that is Class
Outlier, and propose the Class Outlier Factor (COF) which measures
the degree of being a Class Outlier for a data object. Our work
includes a proposal of a new algorithm towards mining of the Class
Outliers, presenting experimental results applied on various domains
of real world datasets and finally a comparison study with other
related methods is performed.
Abstract: Multi criteria decision making (MCDM) methods like analytic hierarchy process, ELECTRE and multi-attribute utility theory are critically studied. They have irregularities in terms of the reliability of ranking of the best alternatives. The Routing Decision Support (RDS) algorithm is trying to improve some of their deficiencies. This paper gives a mathematical verification that the RDS algorithm conforms to the test criteria for an effective MCDM method when a linear preference function is considered.
Abstract: This paper discusses aspects of re-design of loadshedding
schemes with respect to actual developments in the Kosovo
power system. Load-shedding is a type of emergency control that is
designed to ensure system stability by reducing power system load to
match the power generation supply. This paper presents a new
adaptive load-shedding scheme that provides emergency protection
against excess frequency decline, in cases when the Kosovo power
system might be disconnected from the regional transmission
network. The proposed load-shedding scheme uses the local
frequency rate information to adapt the load-shedding pattern to suit
the size and location of the occurring disturbance. The proposed
scheme is tested in a software simulation on a large scale PSS/E
model which represents nine power system areas of Southeast Europe
including the Kosovo power system.
Abstract: At a time of growing market turbulence and a strong
shifts towards increasingly complex risk models and more stringent audit requirements, it is more critical than ever to maintain the highest quality of financial and credit information. IFC implemented
an approach that helps increase data integrity and quality significantly. This approach is called “Screening". Screening is based on linking information from different sources to identify potential
inconsistencies in key financial and credit data. That, in turn, can help
to ease the trials of portfolio supervision, and improve overall company global reporting and assessment systems. IFC experience
showed that when used regularly, Screening led to improved information.
Abstract: Paper is dealing with vulnerability concerning elements of hydrological structures and elements of technological equipments which are acceptable for groundwater resources. The vulnerability assessment stems from the application of the register of hazards and a potential threat to individual water source elements within each type of hazard. The proposed procedure is pattern for assessing the risks of disturbance, damage, or destruction of water source by the identified natural or technological hazards and consequently for classification of these risks in relation to emergency water supply. Using of this procedure was verified on selected groundwater resource in particular region, which seems to be as potentially useful for crisis planning system.
Abstract: The present paper is an experimental investigation of
roughness effects on nucleate pool boiling of refrigerant R113 on
horizontal circular copper surfaces. The copper samples were treated
by different sand paper grit sizes to achieve different surface
roughness. The average surface roughness of the four samples was
0.901, 0.735, 0.65, and 0.09, respectively. The experiments were
performed in the heat flux range of 8 to 200kW/m2. The heat transfer
coefficient was calculated by measuring wall superheat of the
samples and the input heat flux. The results show significant
improvement of heat transfer coefficient as the surface roughness is
increased. It is found that the heat transfer coefficient of the sample
with Ra=0.901 is 3.4, 10.5, and 38.5% higher in comparison with
surfaces with Ra of 0.735, 0.65, and 0.09 at heat flux of 170 kW/m2.
Moreover, the results are compared with literature data and the well
known Cooper correlation.
Abstract: Semiconductor nanomaterials like TiO2 nanoparticles
(TiO2-NPs) approximately less than 100 nm in diameter have become
a new generation of advanced materials due to their novel and
interesting optical, dielectric, and photo-catalytic properties. With the
increasing use of NPs in commerce, to date few studies have
investigated the toxicological and environmental effects of NPs.
Motivated by the importance of TiO2-NPs that may contribute to the
cancer research field especially from the treatment prospective
together with the fractal analysis technique, we have investigated the
effect of TiO2-NPs on colony morphology in the dark condition
using fractal dimension as a key morphological characterization
parameter. The aim of this work is mainly to investigate the cytotoxic
effects of TiO2-NPs in the dark on the growth of human cervical
carcinoma (HeLa) cell colonies from morphological aspect. The in
vitro studies were carried out together with the image processing
technique and fractal analysis. It was found that, these colonies were
abnormal in shape and size. Moreover, the size of the control
colonies appeared to be larger than those of the treated group. The
mean Df +/- SEM of the colonies in untreated cultures was
1.085±0.019, N= 25, while that of the cultures treated with TiO2-NPs
was 1.287±0.045. It was found that the circularity of the control
group (0.401±0.071) is higher than that of the treated group
(0.103±0.042). The same tendency was found in the diameter
parameters which are 1161.30±219.56 μm and 852.28±206.50 μm
for the control and treated group respectively. Possible explanation of
the results was discussed, though more works need to be done in
terms of the for mechanism aspects. Finally, our results indicate that
fractal dimension can serve as a useful feature, by itself or in
conjunction with other shape features, in the classification of cancer
colonies.
Abstract: In this study, an analysis has been performed for
free convection with radiation effect over a thermal forming
nonlinearly stretching sheet. Parameters n, k0, Pr, G represent
the dominance of the nonlinearly effect, radiation effect, heat
transfer and free convection effects which have been presented
in governing equations, respectively. The similarity
transformation and the finite-difference methods have been
used to analyze the present problem. From the results, we find
that the effects of parameters n, k0, Pr, Ec and G to the
nonlinearly stretching sheet. The increase of Prandtl number Pr,
free convection parameter G or radiation parameter k0 resulting
in the increase of heat transfer effects, but increase of the
viscous dissipation number Ec will decrease of heat transfer
effect.
Abstract: Stage bus operated in the mixed traffic might always meet many problems about low quality and reliability of services. The low quality and reliability of bus service can make the system not attractive and directly reduce the interest of using bus service. This paper presents the result of field investigation and analysis of on-time performance and service regularity of stage bus in mixed traffic. Data for analysis was collected from the field by on-board observation along the Ipoh-Lumut corridor in Perak, Malaysia. From analysis and discussion, it can be concluded that on-time performance and service regularity varies depend on station, typical day, time period, operation characteristics of bus and characteristics of traffic. The on-time performance and service regularity of stage bus in mixed traffic can be derived by using data collected by onboard survey. It is clear that on-time performance and service regularity of the existing stage bus system was low.
Abstract: The comparisons of two typical fluidic thrust vectoring exhaust nozzles including two-dimensional(2-D) nozzle and axisymmetric nozzle on aerodynamic characteristics was presented by numerical simulation. The results show: the thrust vector angles increased with the increasing secondary flow but decreased with the nozzle pressure ratio (NPR) increasing. With the same secondary flow and NPR, the thrust vector angles of 2-D nozzle were higher than the axisymmetric nozzle-s. So with the lower NPR and more secondary weight flow, the much higher thrust vector angle was caused by 2-D fluidic nozzle. And with the higher NPR and less secondary weight flow, there was not much difference in angular dimension between two nozzles.
Abstract: Scaffolds play a key role in tissue engineering and can be produced in many different ways depending on the applications and the materials used. Most researchers used an experimental trialand- error approach into new biomaterials but computer simulation applied to tissue engineering can offer a more exhaustive approach to test and screen out biomaterials. This paper develops the model of scaffolds and Computational Fluid Dynamics that show the value of computer simulations in determining the influence of the geometrical scaffold parameter porosity, pore size and shape on the permeability of scaffolds, magnitude of velocity, drop pressure, shear stress distribution and level and the proper design of the geometry of the scaffold. This creates a need for more advanced studies that include aspects of dynamic conditions of a micro fluid passing through the scaffold were characterized for tissue engineering applications and differentiation of tissues within scaffolds.
Abstract: Dietary macro and micro nutrients in their respective proportion and fractions present a practical potential tool to fabricate milk constituents since cells of lactating mammary glands obtain about 80 % of milk synthesis nutrients from blood, reflecting the existence of an isotonic equilibrium between blood and milk. Diverting milk biosynthetic activities through manipulation of nutrients towards producing milk not only keeping in view its significance as natural food but also as food item which prevents or dilutes the adverse effects of some diseases (like cardiovascular problem by saturated milk fat intake) has been area of interest in the last decade. Nutritional modification / supplementation has been reported to enhance conjugated linoleic acid, fatty acid type and concentration, essential fatty acid concentration, vitamin B12& C, Se, Cu, I and Fe which are involved to counter the health threats to human well being. Synchronizing dietary nutrients aimed to modify rumen dynamics towards synthesis of nutrients or their precursors to make their drive towards formulated milk constituents presents a practical option. Formulating dietary constituents to design milk constituents will let the farmers, consumers and investors know about the real potential and profit margins associated with this enterprise. This article briefly recapitulates the ways and means to modify milk constituents keeping an eye on human health and well being issues, which allows milk to serve more than a food item.
Abstract: Complex assemblies of interacting proteins carry out
most of the interesting jobs in a cell, such as metabolism, DNA
synthesis, mitosis and cell division. These physiological properties
play out as a subtle molecular dance, choreographed by underlying
regulatory networks that control the activities of cyclin-dependent
kinases (CDK). The network can be modeled by a set of nonlinear
differential equations and its behavior predicted by numerical
simulation. In this paper, an innovative approach has been proposed
that uses genetic algorithms to mine a set of behavior data output by
a biological system in order to determine the kinetic parameters of
the system. In our approach, the machine learning method is
integrated with the framework of existent biological information in a
wiring diagram so that its findings are expressed in a form of system
dynamic behavior. By numerical simulations it has been illustrated
that the model is consistent with experiments and successfully shown
that such application of genetic algorithms will highly improve the
performance of mathematical model of the cell division cycle to
simulate such a complicated bio-system.
Abstract: Image clustering is a process of grouping images
based on their similarity. The image clustering usually uses the color
component, texture, edge, shape, or mixture of two components, etc.
This research aims to explore image clustering using color
composition. In order to complete this image clustering, three main
components should be considered, which are color space, image
representation (feature extraction), and clustering method itself. We
aim to explore which composition of these factors will produce the
best clustering results by combining various techniques from the
three components. The color spaces use RGB, HSV, and L*a*b*
method. The image representations use Histogram and Gaussian
Mixture Model (GMM), whereas the clustering methods use KMeans
and Agglomerative Hierarchical Clustering algorithm. The
results of the experiment show that GMM representation is better
combined with RGB and L*a*b* color space, whereas Histogram is
better combined with HSV. The experiments also show that K-Means
is better than Agglomerative Hierarchical for images clustering.
Abstract: Selecting the routes and the assignment of link flow in a computer communication networks are extremely complex combinatorial optimization problems. Metaheuristics, such as genetic or simulated annealing algorithms, are widely applicable heuristic optimization strategies that have shown encouraging results for a large number of difficult combinatorial optimization problems. This paper considers the route selection and hence the flow assignment problem. A genetic algorithm and simulated annealing algorithm are used to solve this problem. A new hybrid algorithm combining the genetic with the simulated annealing algorithm is introduced. A modification of the genetic algorithm is also introduced. Computational experiments with sample networks are reported. The results show that the proposed modified genetic algorithm is efficient in finding good solutions of the flow assignment problem compared with other techniques.
Abstract: Gliding during night without electric power is an efficient method to enhance endurance performance of solar aircrafts. The properties of maximum gliding endurance path are studied in this paper. The problem is formulated as an optimization problem about maximum endurance can be sustained by certain potential energy storage with dynamic equations and aerodynamic parameter constrains. The optimal gliding path is generated based on gauss pseudo-spectral method. In order to analyse relationship between altitude, velocity of solar UAVs and its endurance performance, the lift coefficient in interval of [0.4, 1.2] and flight envelopes between 0~30km are investigated. Results show that broad range of lift coefficient can improve solar aircrafts- long endurance performance, and it is possible for a solar aircraft to achieve the aim of long endurance during whole night just by potential energy storage.