Abstract: Most of the drugs used for pharmaceutical purposes
are poorly water-soluble drugs. About 40% of all newly discovered
drugs are lipophilic and the numbers of lipophilic drugs seem to
increase more and more. Drug delivery systems such as
nanoparticles, micelles or liposomes are applied to improve their
solubility and thus their bioavailability. Besides various techniques of
solubilization, oil-in-water emulsions are often used to incorporate
lipophilic drugs into the oil phase. To stabilize emulsions surface
active substances (surfactants) are generally used. An alternative
method to avoid the application of surfactants was of great interest.
One possibility is to develop O/W-emulsion without any addition of
surface active agents or the so called “surfactant-free emulsion or
SFE”. The aim of this study was to develop and characterize SFE as a
drug carrier by varying the production conditions. Lidocaine base
was used as a model drug. The injection method was developed.
Effects of ultrasound as well as of temperature on the properties of
the emulsion were studied. Particle sizes and release were
determined. The long-term stability up to 30 days was performed.
The results showed that the surfactant-free O/W emulsions with
pharmaceutical oil as drug carrier can be produced.
Abstract: In order to study of The Effect of seed inoculation
with Pseudomonas putida+Bacillus lentus on yield and yield
components of wheat (Triticum aestivum L.) cultivars, an experiment
was carried out as factorial based on Randomized Complete Block
Design (RCBD) in Agricultural Research Station of Shahrood
University of Technology. Results showed that inoculation with
Pseudomonas putida+Bacillus lentus promoted seed germination.
Also, inoculation with Pseudomonas putida+Bacillus lentus
significantly affected grain yield, Number of spikes per m2,
Number of grain per spike and 1000-seed weight and There was not
statistically significant difference between Chamran and Pishtaz
cultivars . Finally, the dosages of chemical fertilizers currently
applied in commercial wheat field in Iran (Shahrood region) could be
reduced through proper combination of Pseudomonas
putida+Bacillus lentus inoculation plus fertilization.
Abstract: This paper presents software tools that convert the C/Cµ floating point source code for a DSP algorithm into a fixedpoint simulation model that can be used to evaluate the numericalperformance of the algorithm on several different fixed pointplatforms including microprocessors, DSPs and FPGAs. The tools use a novel system for maintaining binary point informationso that the conversion from floating point to fixed point isautomated and the resulting fixed point algorithm achieves maximum possible precision. A configurable architecture is used during the simulation phase so that the algorithm can produce a bit-exact output for several different target devices.
Abstract: The decision to recruit manpower in an organization
requires clear identification of the criteria (attributes) that distinguish
successful from unsuccessful performance. The choice of appropriate
attributes or criteria in different levels of hierarchy in an organization
is a multi-criteria decision problem and therefore multi-criteria
decision making (MCDM) techniques can be used for prioritization
of such attributes. Analytic Hierarchy Process (AHP) is one such
technique that is widely used for deciding among the complex criteria
structure in different levels. In real applications, conventional AHP
still cannot reflect the human thinking style as precise data
concerning human attributes are quite hard to be extracted. Fuzzy
logic offers a systematic base in dealing with situations, which are
ambiguous or not well defined. This study aims at defining a
methodology to improve the quality of prioritization of an
employee-s performance measurement attributes under fuzziness. To
do so, a methodology based on the Extent Fuzzy Analytic Hierarchy
Process is proposed. Within the model, four main attributes such as
Subject knowledge and achievements, Research aptitude, Personal
qualities and strengths and Management skills with their subattributes
are defined. The two approaches conventional AHP
approach and the Extent Fuzzy Analytic Hierarchy Process approach
have been compared on the same hierarchy structure and criteria set.
Abstract: Selective oxidation of H2S to elemental sulfur in a
fixed bed reactor over newly synthesized alumina nanocatalysts was
physio-chemically investigated and results compared with a
commercial Claus catalyst. Amongst these new materials, Al2O3-
supported sodium oxide prepared with wet chemical technique and
Al2O3 nanocatalyst prepared with spray pyrolysis method were the
most active catalysts for selective oxidation of H2S to elemental
sulfur. Other prepared nanocatalysts were quickly deactivated,
mainly due to the interaction with H2S and conversion into sulfides.
Abstract: Polyphenolics and sugar are the components of many
fruit juices. In this work, the performance of ultra-filtration (UF) for
separating phenolic compounds from apple juice was studied by
performing batch experiments in a membrane module with an area of
0.1 m2 and fitted with a regenerated cellulose membrane of 1 kDa
MWCO. The effects of various operating conditions: transmembrane
pressure (3, 4, 5 bar), temperature (30, 35, 40 ºC), pH (2, 3, 4, 5),
feed concentration (3, 5, 7, 10, 15 ºBrix for apple juice) and feed flow
rate (1, 1.5, 1.8 L/min) on the performance were determined.
The optimum operating conditions were: transmembrane pressure
4 bar, temperature 30 ºC, feed flow rate 1 – 1.8 L/min, pH 3 and 10
Brix (apple juice). After performing ultrafiltration under these
conditions, the concentration of polyphenolics in retentate was
increased by a factor of up to 2.7 with up to 70% recovered in the
permeate and with approx. 20% of the sugar in that stream..
Application of diafiltration (addition of water to the concentrate) can
regain the flux by a factor of 1.5, which has been decreased due to
fouling. The material balance performed on the process has shown
the amount of deposits on the membrane and the extent of fouling in
the system. In conclusion, ultrafiltration has been demonstrated as a
potential technology to separate the polyphenolics and sugars from
their mixtures and can be applied to remove sugars from fruit juice.
Abstract: Contractor selection in Saudi Arabia is very important due to the large construction boom and the contractor role to get over construction risks. The need for investigating contractor selection is due to the following reasons; large number of defaulted or failed projects (18%), large number of disputes attributed to contractor during the project execution stage (almost twofold), the extension of the General Agreement on Tariffs and Trade (GATT) into construction industry, and finally the few number of researches. The selection strategy is not perfect and considered as the reason behind irresponsible contractors. As a response, this research was conducted to review the contractor selection strategies as an integral part of a long advanced research to develop a good selection model. Many techniques can be used to form a selection strategy; multi criteria for optimizing decision, prequalification to discover contractor-s responsibility, bidding process for competition, third party guarantee to enhance the selection, and fuzzy techniques for ambiguities and incomplete information.
Abstract: This paper describes a new method for affine parameter
estimation between image sequences. Usually, the parameter
estimation techniques can be done by least squares in a quadratic
way. However, this technique can be sensitive to the presence
of outliers. Therefore, parameter estimation techniques for various
image processing applications are robust enough to withstand the
influence of outliers. Progressively, some robust estimation functions
demanding non-quadratic and perhaps non-convex potentials adopted
from statistics literature have been used for solving these. Addressing
the optimization of the error function in a factual framework for
finding a global optimal solution, the minimization can begin with
the convex estimator at the coarser level and gradually introduce nonconvexity
i.e., from soft to hard redescending non-convex estimators
when the iteration reaches finer level of multiresolution pyramid.
Comparison has been made to find the performance of the results
of proposed method with the results found individually using two
different estimators.
Abstract: In H.264/AVC video encoding, rate-distortion
optimization for mode selection plays a significant role to achieve
outstanding performance in compression efficiency and video quality.
However, this mode selection process also makes the encoding
process extremely complex, especially in the computation of the ratedistortion
cost function, which includes the computations of the sum
of squared difference (SSD) between the original and reconstructed
image blocks and context-based entropy coding of the block. In this
paper, a transform-domain rate-distortion optimization accelerator
based on fast SSD (FSSD) and VLC-based rate estimation algorithm
is proposed. This algorithm could significantly simplify the hardware
architecture for the rate-distortion cost computation with only
ignorable performance degradation. An efficient hardware structure
for implementing the proposed transform-domain rate-distortion
optimization accelerator is also proposed. Simulation results
demonstrated that the proposed algorithm reduces about 47% of total
encoding time with negligible degradation of coding performance.
The proposed method can be easily applied to many mobile video
application areas such as a digital camera and a DMB (Digital
Multimedia Broadcasting) phone.
Abstract: Wireless LAN technologies have picked up
momentum in the recent years due to their ease of deployment, cost
and availability. The era of wireless LAN has also given rise to
unique applications like VOIP, IPTV and unified messaging.
However, these real-time applications are very sensitive to network
and handoff latencies. To successfully support these applications,
seamless roaming during the movement of mobile station has become
crucial. Nowadays, centralized architecture models support roaming
in WLANs. They have the ability to manage, control and
troubleshoot large scale WLAN deployments. This model is managed
by Control and Provision of Wireless Access Point protocol
(CAPWAP). This paper covers the CAPWAP architectural solution
along with its proposals that have emerged. Based on the literature
survey conducted in this paper, we found that the proposed
algorithms to reduce roaming latency in CAPWAP architecture do
not support seamless roaming. Additionally, they are not sufficient
during the initial period of the network. This paper also suggests
important design consideration for mobility support in future
centralized IEEE 802.11 networks.
Abstract: In recent years in Kazakhstan, as well as in all countries, we have been talking not only about the professional stress, but also professional Burnout Syndrome of employees. Burnout is essentially a response to chronic emotional stress – manifests itself in the form of chronic fatigue, despondency, unmotivated aggression, anger, and others. This condition is due to mental fatigue among teachers as a sort of payment for overstrain when professional commitments include the impact of “heat your soul", emotional investment. The emergence of professional Burnout among teachers is due to the system of interrelated and mutually reinforcing factors relating to the various levels of the personality: individually-psychological level is psychodynamic special subject characteristics of valuemotivational sphere and formation of skills and habits of selfregulation; the socio-psychological level includes especially the Organization and interpersonal interaction of a teacher. Signs of the Burnout were observed in 15 testees, and virtually a symptom could be observed in every teacher. As a result of the diagnosis 48% of teachers had the signs of stress (phase syndrome), resulting in a sense of anxiety, mood, heightened emotional susceptibility. The following results have also been got:-the fall of General energy potential – 14 pers. -Psychosomatic and psycho vegetative syndrome – 26 pers. -emotional deficit-34 pers. -emotional Burnout Syndrome-6 pers. The problem of professional Burnout of teachers in the current conditions should become not only meaningful, but particularly relevant. The quality of education of the younger generation depends on professional development; teachers- training level, and how “healthy" teachers are. That is why the systematic maintenance of pedagogic-professional development for teachers (including disclosure of professional Burnout Syndrome factors) takes on a special meaning.
Abstract: This paper suggests a new Affine Projection (AP) algorithm with variable data-reuse factor using the condition number as a decision factor. To reduce computational burden, we adopt a recently reported technique which estimates the condition number of an input data matrix. Several simulations show that the new algorithm has better performance than that of the conventional AP algorithm.
Abstract: In this paper, a method for matching image segments
using triangle-based (geometrical) regions is proposed. Triangular
regions are formed from triples of vertex points obtained from a
keypoint detector (SIFT). However, triangle regions are subject to
noise and distortion around the edges and vertices (especially acute
angles). Therefore, these triangles are expanded into parallelogramshaped
regions. The extracted image segments inherit an important
triangle property; the invariance to affine distortion. Given two
images, matching corresponding regions is conducted by computing
the relative affine matrix, rectifying one of the regions w.r.t. the other
one, then calculating the similarity between the reference and
rectified region. The experimental tests show the efficiency and
robustness of the proposed algorithm against geometrical distortion.
Abstract: Segmentation, filtering out of measurement errors and
identification of breakpoints are integral parts of any analysis of
microarray data for the detection of copy number variation (CNV).
Existing algorithms designed for these tasks have had some successes
in the past, but they tend to be O(N2) in either computation time or
memory requirement, or both, and the rapid advance of microarray
resolution has practically rendered such algorithms useless. Here we
propose an algorithm, SAD, that is much faster and much less thirsty
for memory – O(N) in both computation time and memory requirement
-- and offers higher accuracy. The two key ingredients of SAD are the
fundamental assumption in statistics that measurement errors are
normally distributed and the mathematical relation that the product of
two Gaussians is another Gaussian (function). We have produced a
computer program for analyzing CNV based on SAD. In addition to
being fast and small it offers two important features: quantitative
statistics for predictions and, with only two user-decided parameters,
ease of use. Its speed shows little dependence on genomic profile.
Running on an average modern computer, it completes CNV analyses
for a 262 thousand-probe array in ~1 second and a 1.8 million-probe
array in 9 seconds
Abstract: Aluminum/Copper clad sheet has been fabricated using
asymmetric extrusion method, which caused severe shear deformation
between Al and Cu plate to easily bond to each other. Interfacial
microstructure and mechanical properties of Al/Cu clad were studied
by scanning electron microscope equipped with energy dispersive
X-ray detector, micro-hardness, and tension tests. The asymmetric
extrusion bonding was very effective to provide a good interface for
atoms diffusion during subsequent annealing. The strength of bonding
was higher with the increasing extrusion ratio.
Abstract: I/O workload is a critical and important factor to
analyze I/O pattern and file system performance. However tracing I/O
operations on the fly distributed parallel file system is non-trivial due
to collection overhead and a large volume of data. In this paper, we
design and implement a parallel file system logging method for high
performance computing using shared memory-based multi-layer
scheme. It minimizes the overhead with reduced logging operation
response time and provides efficient post-processing scheme through
shared memory. Separated logging server can collect sequential logs
from multiple clients in a cluster through packet communication.
Implementation and evaluation result shows low overhead and high
scalability of this architecture for high performance parallel logging
analysis.
Abstract: Food control measures are critical in fostering food safety management of a nation. However, no academic study has been undertaken to assess the food control system of Myanmar up to now. The objective of this research paper was to assess the food control system with in depth examination of five key components using desktop analysis and short survey from related food safety program organizations including regulators and inspectors. Study showed that the existing food control system is conventional, mainly focusing on primary health care approach while relying on reactive measures. The achievements of food control work have been limited to a certain extent due to insufficienttechnical capacity that is needed to upgrade staffs, laboratory equipment and technical assistance etc. associated with various sectors. Assessing food control measures is the first step in the integration of food safety management, this paper could assist policy makers in providing information for enhancing the safety and quality of food produced and consumed in Myanmar.
Abstract: Graph transformation has recently become more and
more popular as a general visual modeling language to formally state
the dynamic semantics of the designed models. Especially, it is a
very natural formalism for languages which basically are graph (e.g.
UML). Using this technique, we present a highly understandable yet
precise approach to formally model and analyze the behavioral
semantics of UML 2.0 Activity diagrams. In our proposal, AGG is
used to design Activities, then using our previous approach to model
checking graph transformation systems, designers can verify and
analyze designed Activity diagrams by checking the interesting
properties as combination of graph rules and LTL (Linear Temporal
Logic) formulas on the Activities.
Abstract: A simple and easy algorithm is presented for a fast calculation of kernel functions which required in fluid simulations using the Smoothed Particle Hydrodynamic (SPH) method. Present proposed algorithm improves the Linked-list algorithm and adopts the Pair-Wise Interaction technique, which are widely used for evaluating kernel functions in fluid simulations using the SPH method. The algorithm is easy to be implemented without any complexities in programming. Some benchmark examples are used to show the simulation time saved by using the proposed algorithm. Parametric studies on the number of divisions for sub-domains, smoothing length and total amount of particles are conducted to show the effectiveness of the present technique. A compact formulation is proposed for practical usage.
Abstract: In online context, the design and implementation of
effective remote laboratories environment is highly challenging on
account of hardware and software needs. This paper presents the
remote laboratory software framework modified from ilab shared
architecture (ISA). The ISA is a framework which enables students to
remotely acccess and control experimental hardware using internet
infrastructure. The need for remote laboratories came after
experiencing problems imposed by traditional laboratories. Among
them are: the high cost of laboratory equipment, scarcity of space,
scarcity of technical personnel along with the restricted university
budget creates a significant bottleneck on building required
laboratory experiments. The solution to these problems is to build
web-accessible laboratories. Remote laboratories allow students and
educators to interact with real laboratory equipment located
anywhere in the world at anytime. Recently, many universities and
other educational institutions especially in third world countries rely
on simulations because they do not afford the experimental
equipment they require to their students. Remote laboratories enable
users to get real data from real-time hand-on experiments. To
implement many remote laboratories, the system architecture should
be flexible, understandable and easy to implement, so that different
laboratories with different hardware can be deployed easily. The
modifications were made to enable developers to add more
equipment in ISA framework and to attract the new developers to
develop many online laboratories.