Abstract: This study, for its research subjects, uses patients who
had undergone total knee replacement surgery from the database of the
National Health Insurance Administration. Through the review of
literatures and the interviews with physicians, important factors are
selected after careful screening. Then using Cross Entropy Method,
Genetic Algorithm Logistic Regression, and Particle Swarm
Optimization, the weight of each factor is calculated and obtained. In
the meantime, Excel VBA and Case Based Reasoning are combined
and adopted to evaluate the system. Results show no significant
difference found through Genetic Algorithm Logistic Regression and
Particle Swarm Optimization with over 97% accuracy in both
methods. Both ROC areas are above 0.87. This study can provide
critical reference to medical personnel as clinical assessment to
effectively enhance medical care quality and efficiency, prevent
unnecessary waste, and provide practical advantages to resource
allocation to medical institutes.
Abstract: Due to today’s globalization as well as outsourcing
practices of the companies, the Supply Chain (SC) performances
have become more dependent on the efficient movement of material
among places that are geographically dispersed, where there is more
chance for disruptions. One such disruption is the quality and
delivery uncertainties of outsourcing. These uncertainties could lead
the products to be unsafe and, as is the case in a number of recent
examples, companies may have to end up in recalling their products.
As a result of these problems, there is a need to develop a
methodology for selecting suppliers globally in view of risks
associated with low quality and late delivery. Accordingly, we
developed a two-stage stochastic model that captures the risks
associated with uncertainty in quality and delivery as well as a
solution procedure for the model. The stochastic model developed
simultaneously optimizes supplier selection and purchase quantities
under price discounts over a time horizon. In particular, our target is
the study of global organizations with multiple sites and multiple
overseas suppliers, where the pricing is offered in suppliers’ local
currencies. Our proposed methodology is applied to a case study for a
US automotive company having two assembly plants and four
potential global suppliers to illustrate how the proposed model works
in practice.
Abstract: In recent years a new method of combination
treatment for cancer has been developed and studied that has led to
significant advancements in the field of cancer therapy. Hyperthermia
is a traditional therapy that, along with a creation of a medically
approved level of heat with the help of an alternating magnetic AC
current, results in the destruction of cancer cells by heat. This paper
gives details regarding the production of the spherical nanocomposite
PVA/γ-Fe2O3 in order to be used for medical purposes such as tumor
treatment by hyperthermia. To reach a suitable and evenly distributed
temperature, the nanocomposite with core-shell morphology and
spherical form within a 100 to 200 nanometer size was created using
phase separation emulsion, in which the magnetic nano-particles γ-
Fe2O3 with an average particle size of 20 nano-meters and with
different percentages of 0.2, 0.4, 0.5 and 0.6 were covered by
polyvinyl alcohol. The main concern in hyperthermia and heat
treatment is achieving desirable specific absorption rate (SAR) and
one of the most critical factors in SAR is particle size. In this project
all attempts has been done to reach minimal size and consequently
maximum SAR. The morphological analysis of the spherical
structure of the nanocomposite PVA/γ-Fe2O3 was achieved by SEM
analyses and the study of the chemical bonds created was made
possible by FTIR analysis. To investigate the manner of magnetic
nanocomposite particle size distribution a DLS experiment was
conducted. Moreover, to determine the magnetic behavior of the γ-
Fe2O3 particle and the nanocomposite PVA/γ-Fe2O3 in different
concentrations a VSM test was conducted. To sum up, creating
magnetic nanocomposites with a spherical morphology that would be
employed for drug loading opens doors to new approaches in
developing nanocomposites that provide efficient heat and a
controlled release of drug simultaneously inside the magnetic field,
which are among their positive characteristics that could significantly
improve the recovery process in patients.
Abstract: Biodiesel, as an alternative renewable fuel, has been
receiving increasing attention due to the limited supply of fossil fuels
and the increasing need for energy. Microalgae are promising source
for lipids, which can be converted to biodiesel. The biodiesel
production from microalgae lipids using lipase catalyzed reaction in
supercritical CO2 medium has several advantages over conventional
production processes. However, identifying the optimum microalgae
lipid extraction and transesterification conditions is still a challenge.
In this study, the quality of biodiesel produced from lipids extracted
from Scenedesmus sp. and their enzymatic transesterification using
supercritical carbon dioxide have been investigated. At the optimum
conditions, the highest biodiesel production yield was found to be
82%. The fuel properties of the produced biodiesel, without any
separation step, at optimum reaction condition, were determined and
compared to ASTM standards. The properties were found to comply
with the limits, and showed a low glycerol content, without any
separation step.
Abstract: Adopting Most Advantageous Tender (MAT) for the
government procurement projects has become popular in Taiwan. As
time pass by, the problems of MAT has appeared gradually. People
condemn two points that are the result might be manipulated by a
single committee member’s partiality and how to make a fair decision
when the winner has two or more. Arrow’s Impossibility Theorem
proposed that the best scoring method should meet the four reasonable
criteria. According to these four criteria this paper constructed an
“Illegitimate Scores Checking Scheme” for a scoring method and used
the scheme to find out the illegitimate of the current evaluation method
of MAT. This paper also proposed a new scoring method that is called
the “Standardizing Overall Evaluated Score Method”. This method
makes each committee member’s influence tend to be identical. Thus,
the committee members can scoring freely according to their partiality
without losing the fairness. Finally, it was examined by a large-scale
simulation, and the experiment revealed that the it improved the
problem of dictatorship and perfectly avoided the situation of cyclical
majorities, simultaneously. This result verified that the Standardizing
Overall Evaluated Score Method is better than any current evaluation
method of MAT.
Abstract: Radial profiles of particle velocities were investigated
in a 6.1m high methanol-to-olefins cold model experimental device
using a TSI laser Doppler velocimeter. The effect of axial height on
flow development was not obvious in fully developed region under the
same operating condition. Superficial gas velocity and solid
circulating rate had significant influence on particle velocity in the
center region of the riser. Besides, comparisons among rising,
descending and average particle velocity were conducted. The particle
average velocity was similar to the rising particle velocity and higher
than the descending particle velocity in radial locations except the wall
region of riser.
Abstract: The article represents the results of isolation and
component chromatographic analysis of essential oils of Polygonum
L. plants growing in Kazakhstan in commercial reserves at the
territory of Kazakhstan. The results of research of antibacterial and
antifungal activity of isolated compounds have been represented.
Abstract: Floorplanning plays a vital role in the physical design
process of Very Large Scale Integrated (VLSI) chips. It is an
essential design step to estimate the chip area prior to the optimized
placement of digital blocks and their interconnections. Since VLSI
floorplanning is an NP-hard problem, many optimization techniques
were adopted in the literature. In this work, a music-inspired
Harmony Search (HS) algorithm is used for the fixed die outline
constrained floorplanning, with the aim of reducing the total chip
area. HS draws inspiration from the musical improvisation process of
searching for a perfect state of harmony. Initially, B*-tree is used to
generate the primary floorplan for the given rectangular hard
modules and then HS algorithm is applied to obtain an optimal
solution for the efficient floorplan. The experimental results of the
HS algorithm are obtained for the MCNC benchmark circuits.
Abstract: This paper presents an application of a “Systematic
Soft Domain Driven Design Framework” as a soft systems approach
to domain-driven design of information systems development. The
framework use SSM as a guiding methodology within which we have
embedded a sequence of design tasks based on the UML leading to
the implementation of a software system using the Naked Objects
framework. This framework have been used in action research
projects that have involved the investigation and modelling of
business processes using object-oriented domain models and the
implementation of software systems based on those domain models.
Within this framework, Soft Systems Methodology (SSM) is used as
a guiding methodology to explore the problem situation and to
develop the domain model using UML for the given business
domain. The framework is proposed and evaluated in our previous
works, and a real case study “Information Retrieval System for
academic research” is used, in this paper, to show further practice and
evaluation of the framework in different business domain. We argue
that there are advantages from combining and using techniques from
different methodologies in this way for business domain modelling.
The framework is overviewed and justified as multimethodology
using Mingers multimethodology ideas.
Abstract: In this paper, we investigated the athermal pressure
behavior of the structural and elastic properties of scheelite BaWO4
phase up to 7 GPa using the ab initio pseudo-potential method. The
calculated lattice parameters pressure relation have been compared
with the experimental values and found to be in good agreement with
these results. Moreover, we present for the first time the investigation
of the elastic properties of this compound using the density functional
perturbation theory (DFPT). It is shown that this phase is
mechanically stable up to 7 GPa after analyzing the calculated elastic
constants. Other relevant quantities such as bulk modulus, pressure
derivative of bulk modulus, shear modulus; Young’s modulus,
Poisson’s ratio, anisotropy factors, Debye temperature and sound
velocity have been calculated. The obtained results, which are
reported for the first time to the best of the author’s knowledge, can
facilitate assessment of possible applications of the title material.
Abstract: Tuberculosis (TB) remains a leading cause of
infectious mortality. It is primarily transmitted by the respiratory
route, individuals with active disease may infect others through
airborne particles which releases when they cough, talk, or sing and
subsequently inhale by others. In order to study the effect of the
Bacilli Calmette-Guerin (BCG) vaccine after vaccination of TB
patient, a Vaccinated Susceptible Infected and Recovered (VSIR)
mathematical model is being developed to achieve the desired
objectives. The mathematical model, so developed, shall be used to
quantify the effect of BCG Vaccine to protect the immigrant young
adult person. Moreover, equations are to be established for the
disease endemic and free equilibrium states and subsequently utilized
in disease stability analysis. The stability analysis will give a
complete picture of disease annihilation from the total population if
the total removal rate from the infectious group should be greater
than total number of dormant infections produced throughout
infectious period.
Abstract: In this paper, we propose a new method for threedimensional
object indexing based on D.A.M.C-S.H.C descriptor
(Direct and Analytical Method for Calculating the Spherical
Harmonics Coefficients). For this end, we propose a direct
calculation of the coefficients of spherical harmonics with perfect
precision. The aims of the method are to minimize, the processing
time on the 3D objects database and the searching time of similar
objects to a request object.
Firstly we start by defining the new descriptor using a new
division of 3-D object in a sphere. Then we define a new distance
which will be tested and prove his efficiency in the search for similar
objects in the database in which we have objects with very various
and important size.
Abstract: In addition to environmental parameters like rain,
temperature diseases on crop is a major factor which affects
production quality & quantity of crop yield. Hence disease
management is a key issue in agriculture. For the management of
disease, it needs to be detected at early stage. So, treat it properly &
control spread of the disease. Now a day, it is possible to use the
images of diseased leaf to detect the type of disease by using image
processing techniques. This can be achieved by extracting features
from the images which can be further used with classification
algorithms or content based image retrieval systems. In this paper,
color image is used to extract the features such as mean and standard
deviation after the process of region cropping. The selected features
are taken from the cropped image with different image size samples.
Then, the extracted features are taken in to the account for
classification using Fuzzy Inference System (FIS).
Abstract: This study aimed to determine the possible protective effects of L‐carnitine against gentamicin‐induced nephrotoxicity. Forty male albino rats were divided into 4 groups (10 rats each); Group 1: normal control, group 2: induced nephrotoxicity (gentamicin 50 mg/kg/day S.C; 8 days), group 3: treated with L‐ carnitine (40 mg/kg/d SC for 12 days) and group 4: treated with L‐ carnitine 4 days before and for 8 days in concomitant with gentamicin. Gentamicin‐induced nephrotoxicity (group 2): caused significant increase in serum urea, creatinine, urinary N‐acetyl‐B‐D‐ glucosaminidase (NAG), gamma glutamyl transpeptidase (GGT), urinary total protein and kidney tissue malondialdehyde (MDA) with significant decrease in serum superoxide dismutase (SOD), serum catalase and creatinine clearance and marked tubular necrosis in the proximal convoluted tubules with interruption in the basement membrane around the necrotic tubule compared to the normal control group. L‐carnitine 4 days before and for 8 days in concomitant with gentamicin (group 4) offered marked decrease in serum urea, serum creatinine, urinary NAG, urinary GGT, urinary proteins and kidney tissue MDA, with marked increase in serum SOD, serum catalase and creatinine clearance with marked improvement in the tubular damage compared to gentamicin‐induced nephrotoxicity group. L‐carnitine administered for 12 days produced no change in the parameters mentioned above as compared to the normal control group. In conclusion: L‐carnitine could reduce most of the biochemical parameters and also improve the histopathological features of kidney asscociated with gentamicin induced‐nephrotoxicity.
Abstract: Hemoglobin (HB) indicates anemia level and by
extension may reflect the nutritional level and perhaps the immunity
of an individual. Some antiretroviral drugs like Zidovudine are
known to cause anemia in people living with HIV/AIDS (PLWHA).
A cross sectional study using demographic data and blood specimen
from 218 female commercial sex workers attending antiretroviral
therapy (ART) clinics was conducted between December, 2009 and
July, 2011 to assess the effect of zidovudine on hematologic, and
RNA viral load of female sex workers receiving antiretroviral
treatment in north western Nigeria. Anemia is a common and serious
complication of both HIV infection and its treatment. In the setting of
HIV infection, anemia has been associated with decreased quality of
life, functional status, and survival. Antiretroviral therapy,
particularly the highly active antiretroviral therapy (HAART), has
been associated with a decrease in the incidence and severity of
anemia in HIV-infected patients who have received a HAART
regimen for at least 1 year. In this study, result has shown that of the
218 patients, 26 with hemoglobin count between 5.1 – 10g/dl were
observed to have the highest viral load count of 300,000 –
350,000copies/ml. It was also observed that most patients (190) with
HB of 10.1 – 15.0g/dl had viral load count of 200,000 – 250,000
copies /ml. An inverse relationship therefore exists i.e. the lower the
hemoglobin level, the higher the viral load count even though the test
statistics did not show any significance between the two (P = 0.206).
This shows that multivariate logistic regression analysis
demonstrated that anemia was associated with a CD4 + cell count
below 50/μL, female sex workers with a viral load above 100,000
copies/mL, who use zidovudine.
Severe anemia was less prevalent in this study population than in
historical comparators; however, mild to moderate anemia rates
remain high. The study therefore recommends that hematological and
virologic parameters be monitored closely in patients receiving first
line ART regimen.
Abstract: Riveting process is one of the important ways to keep
fastening the lap joints in aircraft structures. Failure of aircraft lap
joints directly depends on the stress field in the joint. An important
application of riveting process is in the construction of aircraft
fuselage structures. In this paper, a 3D finite element method is
carried out in order to optimize residual stress field in a riveted lap
joint and also to estimate its fatigue life. In continue, a number of
experiments are designed and analyzed using design of experiments
(DOE). Then, Taguchi method is used to select an optimized case
between different levels of each factor. Besides that, the factor which
affects the most on residual stress field is investigated. Such
optimized case provides the maximum residual stress field. Fatigue
life of the optimized joint is estimated by Paris-Erdogan law. Stress
intensity factors (SIFs) are calculated using both finite element
analysis and experimental formula. In addition, the effect of residual
stress field, geometry and secondary bending are considered in SIF
calculation. A good agreement is found between results of such
methods. Comparison between optimized fatigue life and fatigue life
of other joints has shown an improvement in the joint’s life.
Abstract: Out-migration is an important issue for Georgia as
well as since independence has loosed due to emigration one fifth of
its population. During Soviet time out-migration from USSR was
almost impossible and one of the most important instruments in
regulating population movement within the Soviet Union was the
system of compulsory residential registrations, so-called “propiska”.
Since independent here was not any regulation for migration from
Georgia. The majorities of Georgian migrants go abroad by tourist
visa and then overstay, becoming the irregular labor migrants. The
official statistics on migration published for this period was based on
the administrative system of population registration, were
insignificant in terms of numbers and did not represent the real scope
of these migration movements. This paper discusses the data quality
and methodology of migration statistics in Georgia and we are going
to answer the questions: what is the real reason of increasing
immigration flows according to the official numbers since 2000s?
Abstract: This paper represents the results of experimental work to investigate the suitability of a waste material (WM) for soft soil stabilisation. In addition, the effect of particle size distribution (PSD) of the waste material on its performance as a soil stabiliser was investigated. The WM used in this study is produced from the incineration processes in domestic energy power plant and it is available in two different grades of fineness (coarse waste material (CWM) and fine waste material (FWM)). An intermediate plasticity silty clayey soil with medium organic matter content has been used in this study. The suitability of the CWM and FWM to improve the physical and engineering properties of the selected soil was evaluated dependant on the results obtained from the consistency limits, compaction characteristics (optimum moisture content (OMC) and maximum dry density (MDD)); along with the unconfined compressive strength test (UCS). Different percentages of CWM were added to the soft soil (3, 6, 9, 12 and 15%) to produce various admixtures. Then the UCS test was carried out on specimens under different curing periods (zero, 7, 14, and 28 days) to find the optimum percentage of CWM. The optimum and other two percentages (either side of the optimum content) were used for FWM to evaluate the effect of the fineness of the WM on UCS of the stabilised soil. Results indicated that both types of the WM used in this study improved the physical properties of the soft soil where the index of plasticity (IP) was decreased significantly. IP was decreased from 21 to 13.64 and 13.10 with 12% of CWM and 15% of FWM respectively. The results of the unconfined compressive strength test indicated that 12% of CWM was the optimum and this percentage developed the UCS value from 202kPa to 500kPa for 28 days cured samples, which is equal, approximately 2.5 times the UCS value for untreated soil. Moreover, this percentage provided 1.4 times the value of UCS for stabilized soil-CWA by using FWM which recorded just under 700kPa after 28 days curing.
Abstract: We report herein the development and preliminary mechanical characterization of fully-dense multi-wall carbon nanotube (MWCNT)-reinforced ceramics and glasses based on a completely new methodology termed High Shear Compaction (HSC). The tubes are introduced and bound to the matrix grains by aid of polymeric binders to form flexible green bodies which are sintered and densified by spark plasma sintering to unprecedentedly high densities of 100% of the pure-matrix value. The strategy was validated across a PyrexTM glass / MWCNT composite while no identifiable factors limit application to other types of matrices. Nondestructive evaluation, based on ultrasonics, of the dynamic mechanical properties of the materials including elastic, shear and bulk modulus as well as Poisson’s ratio showed optimum property improvement at 0.5 %wt tube loading while evidence of nanoscalespecific energy dissipative characteristics acting complementary to nanotube bridging and pull-out indicate a high potential in a wide range of reinforcing and multifunctional applications.
Abstract: Total Quality Management (TQM) refers to management methods used to enhance quality and productivity in business organizations. Total Quality Management (TQM) has become a frequently used term in discussions concerning quality. Total Quality management has brought rise in demands on the organizations policy and the customers have gained more importance in the organizations focus. TQM is considered as an important management tool, which helps the organizations to satisfy their customers. In present research critical success factors includes management commitment, customer satisfaction, continuous improvement, work culture and environment, supplier quality management, training and development, employee satisfaction and product/process design are studied. A questionnaire is developed to implement these critical success factors in implementation of total quality management in Indian industry. Questionnaires filled by consulting different industrial organizations. Data collected from questionnaires is analyzed by descriptive and importance indexes.