Abstract: This article briefly reviews the role of Indian
Pharmacopoeia Commission (IPC) for publications of Indian
Pharmacopoeia (IP) and National formulary of India (NFI) to some of
these anticipated changes, informs constituents about how they can
remain updated about progress and upcoming modifications to
official texts, and invites participation in the standards-setting
process, which are helpful to the practitioners, researchers, educators
and policy makers in the field of health care profession.
Abstract: Distributed applications deployed on LEO satellites
and ground stations require substantial communication between
different members in a constellation to overcome the earth
coverage barriers imposed by GEOs. Applications running on LEO
constellations suffer the earth line-of-sight blockage effect. They
need adequate lab testing before launching to space. We propose
a scalable cloud-based network simulation framework to simulate
problems created by the earth line-of-sight blockage. The framework
utilized cloud IaaS virtual machines to simulate LEO satellites
and ground stations distributed software. A factorial ANOVA
statistical analysis is conducted to measure simulator overhead on
overall communication performance. The results showed a very low
simulator communication overhead. Consequently, the simulation
framework is proposed as a candidate for testing LEO constellations
with distributed software in the lab before space launch.
Abstract: Exploration and exploitation capabilities are both
important within Operations as means for improvement when
managed separately, and for establishing dynamic improvement
capabilities when combined in balance. However, it is unclear what
exploration and exploitation capabilities imply in improvement and
development work within an Operations context. So, in order to
better understand how to develop exploration and exploitation
capabilities within Operations, the main characteristics of these
constructs needs to be identified and further understood. Thus, the
objective of this research is to increase the understanding about
exploitation and exploration characteristics, to concretize what they
translates to within the context of improvement and development
work in an Operations unit, and to identify practical challenges. A
literature review and a case study are presented. In the literature
review, different interpretations of exploration and exploitation are
portrayed, key characteristics have been identified, and a deepened
understanding of exploration and exploitation characteristics is
described. The case in the study is an Operations unit, and the aim is
to explore to what extent and in what ways exploration and
exploitation activities are part of the improvement structures and
processes. The contribution includes an identification of key
characteristics of exploitation and exploration, as well as an
interpretation of the constructs. Further, some practical challenges are
identified. For instance, exploration activities tend to be given low
priority, both in daily work as in the manufacturing strategy. Also,
the overall understanding about the concepts of exploitation and
exploration (or any similar aspect of dynamic improvement
capabilities) is very low.
Abstract: The paper develops a Non-Linear Model Predictive
Control (NMPC) of water quality in Drinking Water Distribution
Systems (DWDS) based on the advanced non-linear quality dynamics
model including disinfections by-products (DBPs). A special attention
is paid to the analysis of an impact of the flow trajectories prescribed
by an upper control level of the recently developed two-time scale
architecture of an integrated quality and quantity control in DWDS.
The new quality controller is to operate within this architecture in the
fast time scale as the lower level quality controller. The controller
performance is validated by a comprehensive simulation study based
on an example case study DWDS.
Abstract: Knowledge of bone mechanical properties is important
for bone substitutes design and fabrication, and more efficient
prostheses development. The aim of this study is to characterize the
viscoelastic behavior of bone specimens, through stress relaxation
and fatigue tests performed to trabecular bone samples from bovine
femoral heads. Relaxation tests consisted on preloading the samples
at five different magnitudes and evaluate them for 1020 seconds,
adjusting the results to a KWW mathematical model. Fatigue tests
consisted of 700 load cycles and analyze their status at the end of the
tests. As a conclusion we have that between relaxation stress and
each preload there is linear relation and for samples with initial
Young´s modulus greater than 1.5 GPa showed no effects due fatigue
test loading cycles.
Abstract: In this paper, we are interested in the problem of
finding similar images in a large database. For this purpose we
propose a new algorithm based on a combination of the 2-D
histogram intersection in the HSV space and statistical moments. The
proposed histogram is based on a 3x3 window and not only on the
intensity of the pixel. This approach overcome the drawback of the
conventional 1-D histogram which is ignoring the spatial distribution
of pixels in the image, while the statistical moments are used to
escape the effects of the discretisation of the color space which is
intrinsic to the use of histograms. We compare the performance of
our new algorithm to various methods of the state of the art and we
show that it has several advantages. It is fast, consumes little memory
and requires no learning. To validate our results, we apply this
algorithm to search for similar images in different image databases.
Abstract: In the immunologic sense, clinical infection is a state
of failure of the immune system to combat the pathogenic weapon of
the bacteria invading the host. A motile gram negative vibroid
organism associated with marked mono and poly nuclear cell
responses was traced during the examination of a clinical material
from an infected common carp Cyprinus carpio. On primary plate
culture, growth was shown to be pure, dense population of an
Aeromonas-like colony morphotype. The pure isolate was found to
be; Aerobic, facultatively anaerobic, non-halophilic, grew at 0C, and
37C, oxidase positive utilizes glucose through fermentative pathway,
resist 0/129 and novobiocin, produces alanine and lysine
decarboxylases but non-producing ornithine dehydrolases. Tests for
the in vitro determinants of pathogenicity has shown to be; Betahaemolytic
onto blood agar, gelatinase, casienase and amylase
producer. Three in vivo determinants of pathogenicity were tested as,
the lethal dose fifty, the pathogenesis and pathogenicity. It was
evident that 0.1 milliliter of the causal bacterial cell suspension of a
density 1 x 107 CFU/ml injected intramuscularly into an average of
100gms fish toke five days incubation period, then at the day six
morbidity and mortality were initiated. LD50 was recorded at the day
12 post-infection. Use of an LD50 doses to study the pathogenicity,
reveals mononuclear and polynuclear cell responses, on examining
the stained direct films of the clinical materials from the
experimentally infected fish. Re-isolation tests confirm that the reisolant
is same. The course of the infection in natural case was shown
manifestation of; skin ulceration, haemorrhage and descaling. On
evisceration, the internal organs were shown; congestion in the
intestines, spleen and, air sacs. The induced infection showed a
milder form of these manifestations. The grading of the virulence of
this organism was virulent causing chronic course of infections as
indicated from the pathogenesis and pathogenicity studies. Thus the
infectious bacteria were consistent with Aeromonas hydrophila, and
the infection was chronic.
Abstract: Biomass briquette gasification is regarded as a
promising route for efficient briquette use in energy generation, fuels
and other useful chemicals. However, previous research has been
focused on briquette gasification in fixed bed gasifiers such as
updraft and downdraft gasifiers. Fluidised bed gasifier has the
potential to be effectively sized to medium or large scale. This study
investigated the use of fuel briquettes produced from blends of rice
husks and corn cobs biomass, in a bubbling fluidised bed gasifier.
The study adopted a combination of numerical equations and Aspen
Plus simulation software, to predict the product gas (syngas)
composition base on briquette density and biomass composition
(blend ratio of rice husks to corn cobs). The Aspen Plus model was
based on an experimentally validated model from the literature. The
results based on a briquette size 32 mm diameter and relaxed density
range of 500 to 650kg/m3, indicated that fluidisation air required in
the gasifier increased with increase in briquette density, and the
fluidisation air showed to be the controlling factor compared with the
actual air required for gasification of the biomass briquettes. The
mass flowrate of CO2 in the predicted syngas composition increased
with an increase in air flow, in the gasifier, while CO decreased and
H2 was almost constant. The ratio of H2 to CO for various blends of
rice husks and corn cobs did not significantly change at the designed
process air, but a significant difference of 1.0 was observed between
10/90 and 90/10 % blend of rice husks and corn cobs.
Abstract: This study was aimed to investigate the machining
stability of a spindle tool with different preloaded amount. To this end,
the vibration tests were conducted on the spindle unit with different
preload to assess the dynamic characteristics and machining stability
of the milling machine. Current results demonstrate that the tool tip
frequency response characteristics and the machining stabilities in X
and Y direction are affected to change due to the different preload of
spindle bearings. As found from the results, a high preloaded spindle
tool shows higher limited cutting depth at mid position, while a spindle
with low preload shows a higher limited depth. This indicates that the
machining stability of a milling machine is affected to vary by the
spindle unit when it was assembled with different bearing preload.
Abstract: The research was conducted in order to determine the
organizational socialization levels of nurses working in hospitals in
the form of a descriptive study.
The research population was composed of nurses employed in
public and private sector hospitals in the province of Konya with 0-3
years of professional experience in the hospitals (N=1200); and the
sample was composed of 495 nurses that accepted to take part in the
study voluntarily. Statistical evaluation of data was conducted in
SPSS.16 software.
The results of the study revealed that the total score taken by
nurses at the organizational socialization scale was 262.95; and this
was close to the maximum score. Particularly the departmental
socialization sub-dimension proved to be higher in comparison to the
other two dimensions (organization socialization and task
socialization). Statistically meaningful differences were found in the
levels of organization socialization in relation to the status of
organizational orientation training, level of education and age group.
Abstract: More than 3000 plants of notable phyto-therapeutic
value grow in South Africa; these include Cissampelos capensis,
commonly known in Afrikaans as dawidjie or dawidjiewortel. C.
capensis is the most significant and popular medicinal plant used by
the Khoisan as well as other rural groups in the Western region of
South Africa. Its rhizomes are traditionally used to treat male fertility
problems. Yet, no studies have investigated the effects of this plant or
its extracts on human spermatozoa. Therefore, this study aimed at
investigating the effects of C. capensis rhizome extract (CRE)
fractions on ejaculated human spermatozoa in vitro. Spermatozoa
from a total of 77 semen samples were washed with human tubular
fluid medium supplemented with bovine serum albumin (HTF-BSA)
and incubated for 2 hours with 20 μg/ml progesterone (P4) followed
by incubation with different concentrations (0, 0.05, 0.5, 5, 50, 200
μg/ml) of fractionated CRE (F1=0% MeOH, F2=30% MeOH,
F3=60% MeOH and F4=100% MeOH) for 1.5 hours at 37°C. A
sample without addition of CRE fractions served as control. Samples
were analyzed for sperm motility, reactive oxygen species (ROS),
DNA-fragmentation, acrosome reaction and capacitation. Results
showed that F1 resulted in significantly higher values for ROS,
capacitation and hyper-activation compared to F2, F3, and F4 with
P4-stimulated samples generally having higher values. No significant
effect was found for the other parameters. In conclusion, alkaloids
present in F1 of CRE appear to have triggered sperm intrinsic ROS
production leading to sperm capacitation and acrosome reaction
induced by P4.
Abstract: Steady three-dimensional and two free surface waves
generated by moving bodies are presented, the flow problem to be
simulated is rich in complexity and poses many modeling challenges
because of the existence of breaking waves around the ship hull, and
because of the interaction of the two-phase flow with the turbulent
boundary layer. The results of several simulations are reported. The
first study was performed for NACA0012 of hydrofoil with different
meshes, this section is analyzed at h/c= 1, 0345 for 2D. In the second
simulation a mathematically defined Wigley hull form is used to
investigate the application of a commercial CFD code in prediction of
the total resistance and its components from tangential and normal
forces on the hull wetted surface. The computed resistance and wave
profiles are used to estimate the coefficient of the total resistance for
Wigley hull advancing in calm water under steady conditions. The
commercial CFD software FLUENT version 12 is used for the
computations in the present study. The calculated grid is established
using the code computer GAMBIT 2.3.26. The shear stress k-ωSST
model is used for turbulence modeling and the volume of fluid
technique is employed to simulate the free-surface motion. The
second order upwind scheme is used for discretizing the convection
terms in the momentum transport equations, the Modified HRIC
scheme for VOF discretization. The results obtained compare well
with the experimental data.
Abstract: Image segmentation and color identification is an
important process used in various emerging fields like intelligent
robotics. A method is proposed for the manipulator to grasp and place
the color object into correct location. The existing methods such as
PSO, has problems like accelerating the convergence speed and
converging to a local minimum leading to sub optimal performance.
To improve the performance, we are using watershed algorithm and
for color identification, we are using EPSO. EPSO method is used to
reduce the probability of being stuck in the local minimum. The
proposed method offers the particles a more powerful global
exploration capability. EPSO methods can determine the particles
stuck in the local minimum and can also enhance learning speed as
the particle movement will be faster.
Abstract: Whey is the lactose rich by-product of the dairy
industry, having good amount of nutrient reservoir. Most abundant
nutrients are lactose, soluble proteins, lipids and mineral salts.
Disposing of whey by most of milk plants which do not have proper
pre-treatment system is the major issue. As a result of which, there
can be significant loss of potential food and energy source. Thus,
whey has been explored as the substrate for the synthesis of different
value added products such as enzymes. β-galactosidase is one of the
important enzymes and has become the major focus of research due
to its ability to catalyze both hydrolytic as well as
transgalactosylation reaction simultaneously. The enzyme is widely
used in dairy industry as it catalyzes the transformation of lactose to
glucose and galactose, making it suitable for the lactose intolerant
people. The enzyme is intracellular in both bacteria and yeast,
whereas for molds, it has an extracellular location. The present work
was carried to utilize the whey for the production of β-galactosidase
enzyme using both yeast and fungal cultures. The yeast isolate
Kluyveromyces marxianus WIG2 and various fungal strains have
been used in the present study. Different disruption techniques have
also been investigated for the extraction of the enzyme produced
intracellularly from yeast cells. Among the different methods tested
for the disruption of yeast cells, SDS-chloroform showed the
maximum β-galactosidase activity. In case of the tested fungal
cultures, Aureobasidium pullulans NCIM 1050 was observed to be
the maximum extracellular enzyme producer.
Abstract: Aluminium matrix composites with alumina
reinforcements give superior mechanical & physical properties. Their
applications in several fields like automobile, aerospace, defense,
sports, electronics, bio-medical and other industrial purposes are
becoming essential for the last several decades. In the present work,
fabrication of hybrid composite was done by Stir casting technique
using Al 6061 as a matrix with alumina and silicon carbide (SiC) as
reinforcement materials. The weight percentage of alumina is varied
from 2 to 4% and the silicon carbide weight percentage is maintained
constant at 2%. Hardness and wear tests are performed in the as cast
and heat treated conditions. Age hardening treatment was performed
on the specimen with solutionizing at 550°C, aging at two
temperatures (150 and 200°C) for different time durations. Hardness
distribution curves are drawn and peak hardness values are recorded.
Hardness increase was very sensitive with respect to the decrease in
aging temperature. There was an improvement in wear resistance of
the peak aged material when aged at lower temperature. Also
increase in weight percent of alumina, increases wear resistance at
lower temperature but opposite behavior was seen when aged at
higher temperature.
Abstract: This paper participates in giving new vision and
explains the learning and acquisition processes of English language
by analyzing a certain context. Five important factors in English
language acquisition and learning are discussed and suitable solutions
are provided. The factors are compared with the learners' linguistic
background at Bisha College of Technology BCT attempting to link
the issues faced by students and the research done on similar
situations. These factors are phonology, age of acquisition,
motivation, psychology and courses of English. These factors are
very important; because they interfere and affect specific learning
processes at BCT context and general English learning situations.
Abstract: This study examines the feasibility of indirect solar
desalination in oil producing countries in the Middle East and North
Africa (MENA) region. It relies on value engineering (VE) and costbenefit
with sensitivity analyses to identify optimal coupling
configurations of desalination and solar energy technologies. A
comparative return on investment was assessed as a function of water
costs for varied plant capacities (25,000 to 75,000 m3/day), project
lifetimes (15 to 25 years), and discount rates (5 to 15%) taking into
consideration water and energy subsidies, land cost as well as
environmental externalities in the form of carbon credit related to
greenhouse gas (GHG) emissions reduction. The results showed
reverse osmosis (RO) coupled with photovoltaic technologies (PVs)
as the most promising configuration, robust across different prices for
Brent oil, discount rates, as well as different project lifetimes.
Environmental externalities and subsidies analysis revealed that a
16% reduction in existing subsidy on water tariffs would ensure
economic viability. Additionally, while land costs affect investment
attractiveness, the viability of RO coupled with PV remains possible
for a land purchase cost
Abstract: When neck pain is associated with pain, numbness, or
weakness in the arm, shoulder, or hand, further investigation is
needed as these are symptoms indicating pressure on one or more
nerve roots. Evaluation necessitates a neurologic examination and
imaging using an MRI/CT scan. A degenerating disc loses some
thickness and is less flexible, causing inter-vertebrae space to narrow.
A radiologist diagnoses an Intervertebral Disc Degeneration (IDD) by
localizing every inter-vertebral disc and identifying the pathology in
a disc based on its geometry and appearance. Accurate localizing is
necessary to diagnose IDD pathology. But, the underlying image
signal is ambiguous: a disc’s intensity overlaps the spinal nerve
fibres. Even the structure changes from case to case, with possible
spinal column bending (scoliosis). The inter-vertebral disc
pathology’s quantitative assessment needs accurate localization of the
cervical region discs. In this work, the efficacy of multilevel set
segmentation model, to segment cervical discs is investigated. The
segmented images are annotated using a simple distance matrix.
Abstract: Steady three-dimensional and two free surface waves
generated by moving bodies are presented, the flow problem to be
simulated is rich in complexity and poses many modeling challenges
because of the existence of breaking waves around the ship hull, and
because of the interaction of the two-phase flow with the turbulent
boundary layer. The results of several simulations are reported. The
first study was performed for NACA0012 of hydrofoil with different
meshes, this section is analyzed at h/c= 1, 0345 for 2D. In the second
simulation a mathematically defined Wigley hull form is used to
investigate the application of a commercial CFD code in prediction of
the total resistance and its components from tangential and normal
forces on the hull wetted surface. The computed resistance and wave
profiles are used to estimate the coefficient of the total resistance for
Wigley hull advancing in calm water under steady conditions. The
commercial CFD software FLUENT version 12 is used for the
computations in the present study. The calculated grid is established
using the code computer GAMBIT 2.3.26. The shear stress k-ωSST
model is used for turbulence modeling and the volume of fluid
technique is employed to simulate the free-surface motion. The
second order upwind scheme is used for discretizing the convection
terms in the momentum transport equations, the Modified HRIC
scheme for VOF discretization. The results obtained compare well
with the experimental data.
Abstract: The Economic Lot Scheduling Problem (ELSP) is a
valuable mathematical model that can support decision-makers to
make scheduling decisions. The basic period approach is effective for
solving the ELSP. The assumption for applying the basic period
approach is that a product must use its maximum production rate to be
produced. However, a product can lower its production rate to reduce
the average total cost when a facility has extra idle time. The past
researches discussed how a product adjusts its production rate under
the common cycle approach. To the best of our knowledge, no studies
have addressed how a product lowers its production rate under the
basic period approach. This research is the first paper to discuss this
topic. The research develops a simple fixed rate approach that adjusts
the production rate of a product under the basic period approach to
solve the ELSP. Our numerical example shows our approach can find a
better solution than the traditional basic period approach. Our
mathematical model that applies the fixed rate approach under the
basic period approach can serve as a reference for other related
researches.