An LMI Approach of Robust H∞ Fuzzy State-Feedback Controller Design for HIV/AIDS Infection System with Dual Drug Dosages

This paper examines the problem of designing robust H controllers for for HIV/AIDS infection system with dual drug dosages described by a Takagi-Sugeno (S) fuzzy model. Based on a linear matrix inequality (LMI) approach, we develop an H controller which guarantees the L2-gain of the mapping from the exogenous input noise to the regulated output to be less than some prescribed value for the system. A sufficient condition of the controller for this system is given in term of Linear Matrix Inequalities (LMIs). The effectiveness of the proposed controller design methodology is finally demonstrated through simulation results. It has been shown that the anti-HIV vaccines are critically important in reducing the infected cells.

An Inductive Coupling Based CMOS Wireless Powering Link for Implantable Biomedical Applications

A closed-loop controlled wireless power transmission circuit block for implantable biomedical applications is described in this paper. The circuit consists of one front-end rectifier, power management sub-block including bandgap reference and low drop-out regulators (LDOs) as well as transmission power detection / feedback circuits. Simulation result shows that the front-end rectifier achieves 80% power efficiency with 750-mV single-end peak-to-peak input voltage and 1.28-V output voltage under load current of 4 mA. The power management block can supply 1.8mA average load current under 1V consuming only 12μW power, which is equivalent to 99.3% power efficiency. The wireless power transmission block described in this paper achieves a maximum power efficiency of 80%. The wireless power transmission circuit block is designed and implemented using UMC 65-nm CMOS/RF process. It occupies 1 mm × 1.2 mm silicon area.

Analysis of Event-related Response in Human Visual Cortex with fMRI

Functional Magnetic Resonance Imaging(fMRI) is a noninvasive imaging technique that measures the hemodynamic response related to neural activity in the human brain. Event-related functional magnetic resonance imaging (efMRI) is a form of functional Magnetic Resonance Imaging (fMRI) in which a series of fMRI images are time-locked to a stimulus presentation and averaged together over many trials. Again an event related potential (ERP) is a measured brain response that is directly the result of a thought or perception. Here the neuronal response of human visual cortex in normal healthy patients have been studied. The patients were asked to perform a visual three choice reaction task; from the relative response of each patient corresponding neuronal activity in visual cortex was imaged. The average number of neurons in the adult human primary visual cortex, in each hemisphere has been estimated at around 140 million. Statistical analysis of this experiment was done with SPM5(Statistical Parametric Mapping version 5) software. The result shows a robust design of imaging the neuronal activity of human visual cortex.

PIV Investigation into the Evolution of Vortical Structures in the Zero Pressure Gradient Boundary Layer

Experimental investigation has been carried out towards understanding the complex fluid dynamics involved in the interaction of vortical structures with zero pressure gradient boundary layer. A laminar boundary layer is produced on the flat plate placed in the water flume and the synthetic jet actuator is deployed on top of the plate at a definite distance from the leading edge. The synthetic jet actuator has been designed in such a way that the to and fro motion of the diaphragm is maneuvered at will by varying the operating parameters to produce the typical streamwise vortical structures namely hairpin and tilted vortices. PIV measurements are made on the streamwise plane normal to the plate to evaluate their interaction with the near wall fluid.

Design of the Propelling Nozzles for the Launchers and Satellites

The aim of this work is to determine the supersonic nozzle profiles used in propulsion, for the launchers or embarked with the satellites. This design has as a role firstly, to give a important propulsion, i.e. with uniform and parallel flow at exit, secondly to find a short length profiles without modification of the flow in the nozzle. The first elaborate program is used to determine the profile of divergent by using the characteristics method for an axisymmetric flow. The second program is conceived by using the finite volume method to determine and test the profile found connected to a convergent.

Design of a Neural Networks Classifier for Face Detection

Face detection and recognition has many applications in a variety of fields such as security system, videoconferencing and identification. Face classification is currently implemented in software. A hardware implementation allows real-time processing, but has higher cost and time to-market. The objective of this work is to implement a classifier based on neural networks MLP (Multi-layer Perceptron) for face detection. The MLP is used to classify face and non-face patterns. The systm is described using C language on a P4 (2.4 Ghz) to extract weight values. Then a Hardware implementation is achieved using VHDL based Methodology. We target Xilinx FPGA as the implementation support.

Design and Implementation of a Neural Network for Real-Time Object Tracking

Real-time object tracking is a problem which involves extraction of critical information from complex and uncertain imagedata. In this paper, we present a comprehensive methodology to design an artificial neural network (ANN) for a real-time object tracking application. The object, which is tracked for the purpose of demonstration, is a specific airplane. However, the proposed ANN can be trained to track any other object of interest. The ANN has been simulated and tested on the training and testing datasets, as well as on a real-time streaming video. The tracking error is analyzed with post-regression analysis tool, which finds the correlation among the calculated coordinates and the correct coordinates of the object in the image. The encouraging results from the computer simulation and analysis show that the proposed ANN architecture is a good candidate solution to a real-time object tracking problem.

Comparison of Two Airfoil Sections for Application in Straight-Bladed Darrieus VAWT

This paper presents a model for the evaluation of energy performance and aerodynamic forces acting on a small straight-bladed Darrieus-type vertical axis wind turbine depending on blade geometrical section. It consists of an analytical code coupled to a solid modeling software, capable of generating the desired blade geometry based on the desired blade design geometric parameters. Such module is then linked to a finite volume commercial CFD code for the calculation of rotor performance by integration of the aerodynamic forces along the perimeter of each blade for a full period of revolution.After describing and validating the computational model with experimental data, the results of numerical simulations are proposed on the bases of two candidate airfoil sections, that is a classical symmetrical NACA 0021 blade profile and the recently developed DU 06-W-200 non-symmetric and laminar blade profile.Through a full CFD campaign of analysis, the effects of blade geometrical section on angle of attack are first investigated and then the overall rotor torque and power are analyzed as a function of blade azimuthal position, achieving a numerical quantification of the influence of airfoil geometry on overall rotor performance.

Study on Numerical Simulation Applied to Moisture Buffering Design Method – The Case Study of Pine Wood in a Single Zone Residential Unit in Taiwan

A good green building design project, designers should consider not only energy consumption, but also healthy and comfortable needs of inhabitants. In recent years, the Taiwan government paid attentions on both carbon reduction and indoor air quality issues, which be presented in the legislation of Building Codes and other regulations. Taiwan located in hot and humid climates, dampness in buildings leads to significant microbial pollution and building damage. This means that the high temperature and humidity present a serious indoor air quality issue. The interactions between vapor transfers and energy fluxes are essential for the whole building Heat Air and Moisture (HAM) response. However, a simulation tool with short calculation time, property accuracy and interface is needed for practical building design processes. In this research, we consider the vapor transfer phenomenon of building materials as well as temperature and humidity and energy consumption in a building space. The simulation bases on the EMPD method, which was performed by EnergyPlus, a simulation tool developed by DOE, to simulate the indoor moisture variation in a one-zone residential unit based on the Effective Moisture Penetration Depth Method, which is more suitable for practical building design processes.

Reasoning With Non-Binary Logics

Students in high education are presented with new terms and concepts in nearly every lecture they attend. Many of them prefer Web-based self-tests for evaluation of their concepts understanding since they can use those tests independently of tutors- working hours and thus avoid the necessity of being in a particular place at a particular time. There is a large number of multiple-choice tests in almost every subject designed to contribute to higher level learning or discover misconceptions. Every single test provides immediate feedback to a student about the outcome of that test. In some cases a supporting system displays an overall score in case a test is taken several times by a student. What we still find missing is how to secure delivering of personalized feedback to a user while taking into consideration the user-s progress. The present work is motivated to throw some light on that question.

Modeling the Country Selection Decision in Retail Internationalization

This paper aims to develop a model that assists the international retailer in selecting the country that maximizes the degree of fit between the retailer-s goals and the country characteristics in his initial internationalization move. A two-stage multi criteria decision model is designed integrating the Analytic Hierarchy Process (AHP) and Goal Programming. Ethical, cultural, geographic and economic proximity are identified as the relevant constructs of the internationalization decision. The constructs are further structured into sub-factors within analytic hierarchy. The model helps the retailer to integrate, rank and weigh a number of hard and soft factors and prioritize the countries accordingly. The model has been implemented on a Turkish luxury goods retailer who was planning to internationalize. Actual entry of the specific retailer in the selected country is a support for the model. Implementation on a single retailer limits the generalizability of the results; however, the emphasis of the paper is on construct identification and model development. The paper enriches the existing literature by proposing a hybrid multi objective decision model which introduces new soft dimensions i.e. perceived distance, ethical proximity, humane orientation to the decision process and facilitates effective decision making.

Interaction at a Distance – An Approach for Redesigning for Distance Education

Different forms of interaction are an integral part of modern courses. Traditional courses held on-campus might focus on teacher-student interaction, or student-student interaction, or both. However when these traditional on-campus courses are to be held as distance courses there is a risk that these well-designed interactions will be difficult or impossible to uphold. For example, studentstudent interaction in traditional project assignments might not work well if the students are scattered across the world. Thus, even a welldesigned traditional on-site course cannot without modification be turned into a distance course. Traditional on-site courses simply have to be redesigned to become true distance courses. This paper describes a structured approach which facilitates the redesign of a traditional course into a distance course. The approach is based on that the desired forms of course flexibility are identified, and thereafter that the course activities are redesigned to facilitate interaction in a distance course. The approach is making use of known patterns of pedagogic interaction and existing guidelines for distance education design. The approach is illustrated with an example course in the field of information systems design.

Verification of Protocol Design using UML - SMV

In recent past, the Unified Modeling Language (UML) has become the de facto industry standard for object-oriented modeling of the software systems. The syntax and semantics rich UML has encouraged industry to develop several supporting tools including those capable of generating deployable product (code) from the UML models. As a consequence, ensuring the correctness of the model/design has become challenging and extremely important task. In this paper, we present an approach for automatic verification of protocol model/design. As a case study, Session Initiation Protocol (SIP) design is verified for the property, “the CALLER will not converse with the CALLEE before the connection is established between them ". The SIP is modeled using UML statechart diagrams and the desired properties are expressed in temporal logic. Our prototype verifier “UML-SMV" is used to carry out the verification. We subjected an erroneous SIP model to the UML-SMV, the verifier could successfully detect the error (in 76.26ms) and generate the error trace.

Laser Welded Ni-Cr Dental Alloys Inspection

Minor problems arising from optimizations by welding of fixed prostheses frameworks can be identified by macroscopic and microscopic visual inspection. The purpose of this study was to highlight the visible discontinuities present in the laser welds of dental Ni-Cr alloys. Ni-Cr base metal alloys designated for fixed prostheses manufacture were selected for the experiments. Using cast plates, preliminary tests were conducted by laser welding. Macroscopic visual inspection was done carefully to assess the defects of the welding rib. Electron microscopy images allowed visualization of small discontinuities, which escapes visual inspection. Making comparison to Ni-Cr alloys taken in the experiment and laser welded, after visual analysis, the best welds appear for Heraenium NA alloy.

The Feasibility of Augmenting an Augmented Reality Image Card on a Quick Response Code

This research attempts to study the feasibility of augmenting an augmented reality (AR) image card on a Quick Response (QR) code. The authors have developed a new visual tag, which contains a QR code and an augmented AR image card. The new visual tag has features of reading both of the revealed data of the QR code and the instant data from the AR image card. Furthermore, a handheld communicating device is used to read and decode the new visual tag, and then the concealed data of the new visual tag can be revealed and read through its visual display. In general, the QR code is designed to store the corresponding data or, as a key, to access the corresponding data from the server through internet. Those reveled data from the QR code are represented in text. Normally, the AR image card is designed to store the corresponding data in 3-Dimensional or animation/video forms. By using QR code's property of high fault tolerant rate, the new visual tag can access those two different types of data by using a handheld communicating device. The new visual tag has an advantage of carrying much more data than independent QR code or AR image card. The major findings of this research are: 1) the most efficient area for the designed augmented AR card augmenting on the QR code is 9% coverage area out of the total new visual tag-s area, and 2) the best location for the augmented AR image card augmenting on the QR code is located in the bottom-right corner of the new visual tag.

Pulsation Suppression Device Design for Reciprocating Compressor

Design and evaluation of reciprocating compressors should include a pulsation study. The object is to ensure that predicted pulsation levels meet guidelines to limit vibration, shaking forces, noise, associated pressure drops, horsepower losses and fabrication cost and time to acceptable levels. This paper explains procedures and recommendations to select and size pulsation suppression devices to obtain optimum arrangement in terms of pulsation, vibration, shaking forces, performance, reliability, safety, operation, maintenance and commercial conditions. Model and advanced formulations for pulsation study are presented. The effect of the full fluid dynamic model on the prediction of pulsation waves and resulting frequency spectrum distributions are discussed. Advanced and optimum methods of controlling pulsations are highlighted. Useful recommendations and guidelines for pulsation control, piping pulsation analysis, pulsation vessel design, shaking forces, low pressure drop orifices, pulsation study report and devices to mitigate pulsation and shaking problems are discussed.

A Sensorless Robust Tracking Control of an Implantable Rotary Blood Pump for Heart Failure Patients

Physiological control of a left ventricle assist device (LVAD) is generally a complicated task due to diverse operating environments and patient variability. In this work, a tracking control algorithm based on sliding mode and feed forward control for a class of discrete-time single input single output (SISO) nonlinear uncertain systems is presented. The controller was developed to track the reference trajectory to a set operating point without inducing suction in the ventricle. The controller regulates the estimated mean pulsatile flow Qp and mean pulsatility index of pump rotational speed PIω that was generated from a model of the assist device. We recall the principle of the sliding mode control theory then we combine the feed-forward control design with the sliding mode control technique to follow the reference trajectory. The uncertainty is replaced by its upper and lower boundary. The controller was tested in a computer simulation covering two scenarios (preload and ventricular contractility). The simulation results prove the effectiveness and the robustness of the proposed controller

Source of Oseltamivir Resistance Due to R152K Mutation of Influenza B Virus Neuraminidase: Molecular Modeling

Every 2-3 years the influenza B virus serves epidemics. Neuraminidase (NA) is an important target for influenza drug design. Although, oseltamivir, an oral neuraminidase drug, has been shown good inhibitory efficiency against wild-type of influenza B virus, the lower susceptibility to the R152K mutation has been reported. Better understanding of oseltamivir efficiency and resistance toward the influenza B NA wild-type and R152K mutant, respectively, could be useful for rational drug design. Here, two complex systems of wild-type and R152K NAs with oseltamivir bound were studied using molecular dynamics (MD) simulations. Based on 5-ns MD simulation, the loss of notable hydrogen bond and decrease in per-residue decomposition energy from the mutated residue K152 contributed to drug compared to those of R152 in wildtype were found to be a primary source of high-level of oseltamivir resistance due to the R152K mutation.

Automation of Packing Cell in Fresh Fish Facilities

The problem discussed in this paper involves packing fresh fish fileet of the northern Cod into a standard square container. The fish is first cleaned and split and then collected on a belt ready to be stacked in a container. The aim of our work is to pack the fish into the container with constraints on the amount of overlap allowed for the fileets. The current focus is to design a packing cell that can be real-time and of practical use, while finding the optimal solution to the degree of overlap and minimise the unused space of the container.

Investigation of Advanced Oxidation Process for the Removal of Residual Carbaryl from Drinking Water Resources

A laboratory set-up was designed to survey the effectiveness of UV/O3 advanced oxidation process (AOP) for the removal of Carbaryl from polluted water in batch reactor. The study was carried out by UV/O3 process for water samples containing 1 to 20 mg/L of Carbaryl in distilled water. Also the range of drinking water resources adjusted in synthetic water and effects of contact time, pH and Carbaryl concentration were studied. The residual pesticide concentration was determined by applying high performance liquid chromatography (HPLC). The results indicated that increasing of retention time and pH, enhances pesticide removal efficiency. The removal efficiency has been affected by pesticide initial concentration. Samples with low pesticide concentration showed a remarkable removal efficiency compared to the samples with high pesticide concentration. AOP method showed the removal efficiencies of 80% to 100%. Although process showed high performance for removal of pesticide from water samples, this process has different disadvantages including complication, intolerability, difficulty of maintenance and equipmental and structural requirements.