Abstract: Identifying the nature of protein-nanoparticle
interactions and favored binding sites is an important issue in
functional characterization of biomolecules and their physiological
responses. Herein, interaction of silver nanoparticles with lysozyme
as a model protein has been monitored via fluorescence spectroscopy.
Formation of complex between the biomolecule and silver
nanoparticles (AgNPs) induced a steady state reduction in the
fluorescence intensity of protein at different concentrations of
nanoparticles. Tryptophan fluorescence quenching spectra suggested
that silver nanoparticles act as a foreign quencher, approaching the
protein via this residue. Analysis of the Stern-Volmer plot showed
quenching constant of 3.73 μM−1. Moreover, a single binding site in
lysozyme is suggested to play role during interaction with AgNPs,
having low affinity of binding compared to gold nanoparticles.
Unfolding studies of lysozyme showed that complex of lysozyme-
AgNPs has not undergone structural perturbations compared to the
bare protein. Results of this effort will pave the way for utilization of
sensitive spectroscopic techniques for rational design of
nanobiomaterials in biomedical applications.
Abstract: Many exist studies always use Markov decision
processes (MDPs) in modeling optimal route choice in
stochastic, time-varying networks. However, taking many
variable traffic data and transforming them into optimal route
decision is a computational challenge by employing MDPs in
real transportation networks. In this paper we model finite
horizon MDPs using directed hypergraphs. It is shown that the
problem of route choice in stochastic, time-varying networks
can be formulated as a minimum cost hyperpath problem, and
it also can be solved in linear time. We finally demonstrate the
significant computational advantages of the introduced
methods.
Abstract: Nowadays, Gene Ontology has been used widely by many researchers for biological data mining and information retrieval, integration of biological databases, finding genes, and incorporating knowledge in the Gene Ontology for gene clustering. However, the increase in size of the Gene Ontology has caused problems in maintaining and processing them. One way to obtain their accessibility is by clustering them into fragmented groups. Clustering the Gene Ontology is a difficult combinatorial problem and can be modeled as a graph partitioning problem. Additionally, deciding the number k of clusters to use is not easily perceived and is a hard algorithmic problem. Therefore, an approach for solving the automatic clustering of the Gene Ontology is proposed by incorporating cohesion-and-coupling metric into a hybrid algorithm consisting of a genetic algorithm and a split-and-merge algorithm. Experimental results and an example of modularized Gene Ontology in RDF/XML format are given to illustrate the effectiveness of the algorithm.
Abstract: In its attempt to offer new ways into autonomy for a
large population of disabled people, assistive technology has largely
been inspired by robotics engineering. Recent human-like robots
carry new hopes that it seems to us necessary to analyze by means of
a specific theory of anthropomorphism. We propose to distinguish a
functional anthropomorphism which is the one of actual wheelchairs
from a structural anthropomorphism based on a mimicking of human
physiological systems. If functional anthropomorphism offers the
main advantage of eliminating the physiological systems
interdependence issue, the highly link between the robot for disabled
people and their human-built environment would lead to privilege in
the future the anthropomorphic structural way. In this future
framework, we highlight a general interdependence principle : any
partial or local structural anthropomorphism generates new
anthropomorphic needs due to the physiological systems
interdependency, whose effects can be evaluated by means of
specific anthropomorphic criterions derived from a set theory-based
approach of physiological systems.
Abstract: In this paper, we present a new algorithm for clustering data in large datasets using image processing approaches. First the dataset is mapped into a binary image plane. The synthesized image is then processed utilizing efficient image processing techniques to cluster the data in the dataset. Henceforth, the algorithm avoids exhaustive search to identify clusters. The algorithm considers only a small set of the data that contains critical boundary information sufficient to identify contained clusters. Compared to available data clustering techniques, the proposed algorithm produces similar quality results and outperforms them in execution time and storage requirements.
Abstract: The one-class support vector machine “support vector
data description” (SVDD) is an ideal approach for anomaly or outlier
detection. However, for the applicability of SVDD in real-world
applications, the ease of use is crucial. The results of SVDD are
massively determined by the choice of the regularisation parameter C
and the kernel parameter of the widely used RBF kernel. While for
two-class SVMs the parameters can be tuned using cross-validation
based on the confusion matrix, for a one-class SVM this is not
possible, because only true positives and false negatives can occur
during training. This paper proposes an approach to find the optimal
set of parameters for SVDD solely based on a training set from
one class and without any user parameterisation. Results on artificial
and real data sets are presented, underpinning the usefulness of the
approach.
Abstract: Due to today-s fierce competition, companies have to
be proactive creators of the future by effectively developing
innovations. Especially radical innovations allow high profit margins
– but they also entail high risks. One possibility to realize radical
innovations and reduce the risk of failure is cross-industry innovation
(CII). CII brings together problems and solution ideas from different
industries. However, there is a lack of systematic ways towards CII.
Bridging this gap, the present paper provides a systematic approach
towards planned CII. Starting with the analysis of potentials, the
definition of promising search strategies is crucial. Subsequently,
identified solution ideas need to be assessed. For the most promising
ones, the adaption process has to be systematically planned –
regarding the risk affinity of a company. The introduced method is
explained on a project from the furniture industry.
Abstract: A novel PDE solver using the multidimensional wave
digital filtering (MDWDF) technique to achieve the solution of a 2D
seismic wave system is presented. In essence, the continuous physical
system served by a linear Kirchhoff circuit is transformed to an
equivalent discrete dynamic system implemented by a MD wave
digital filtering (MDWDF) circuit. This amounts to numerically
approximating the differential equations used to describe elements of a
MD passive electronic circuit by a grid-based difference equations
implemented by the so-called state quantities within the passive
MDWDF circuit. So the digital model can track the wave field on a
dense 3D grid of points. Details about how to transform the continuous
system into a desired discrete passive system are addressed. In
addition, initial and boundary conditions are properly embedded into
the MDWDF circuit in terms of state quantities. Graphic results have
clearly demonstrated some physical effects of seismic wave (P-wave
and S–wave) propagation including radiation, reflection, and
refraction from and across the hard boundaries. Comparison between
the MDWDF technique and the finite difference time domain (FDTD)
approach is also made in terms of the computational efficiency.
Abstract: Road transportation system is the most important
method of transporting the goods. Considering the most suitable
geographical situation of Iran to transport the goods between Europe
and Asia and placement of this country in direction of international
corridors (east- west) , (north-south) and Asian land transport to
infrastructure development “A.L.T.I.D" and Transport corridor
Europe - Caucasus - Asia “T.R.A.C.E.C.A", noticing the security of
road transportation system in this country is so important. In this
paper the main factors of accidents on the roads of Iran are
categorized regarding the rate of accidents occurred. Then apart from
studying the main reasons of accidents of every category, the main
factors of these events are studied and its strategies in Iran are
introduced.
Abstract: The performance of adaptive beamforming degrades
substantially in the presence of steering vector mismatches. This
degradation is especially severe in the near-field, for the
3-dimensional source location is more difficult to estimate than the
2-dimensional direction of arrival in far-field cases. As a solution, a
novel approach of near-field robust adaptive beamforming (RABF) is
proposed in this paper. It is a natural extension of the traditional
far-field RABF and belongs to the class of diagonal loading
approaches, with the loading level determined based on worst-case
performance optimization. However, different from the methods
solving the optimal loading by iteration, it suggests here a simple
closed-form solution after some approximations, and consequently,
the optimal weight vector can be expressed in a closed form. Besides
simplicity and low computational cost, the proposed approach reveals
how different factors affect the optimal loading as well as the weight
vector. Its excellent performance in the near-field is confirmed via a
number of numerical examples.
Abstract: Enzymatic saccharification of biomass for reducing
sugar production is one of the crucial processes in biofuel production
through biochemical conversion. In this study, enzymatic
saccharification of dilute potassium hydroxide (KOH) pre-treated
Tetraselmis suecica biomass was carried out by using cellulase
enzyme obtained from Trichoderma longibrachiatum. Initially, the
pre-treatment conditions were optimised by changing alkali reagent
concentration, retention time for reaction, and temperature. The T.
suecica biomass after pre-treatment was also characterized using
Fourier Transform Infrared Spectra and Scanning Electron
Microscope. These analyses revealed that the functional group such
as acetyl and hydroxyl groups, structure and surface of T. suecica
biomass were changed through pre-treatment, which is favourable for
enzymatic saccharification process. Comparison of enzymatic
saccharification of untreated and pre-treated microalgal biomass
indicated that higher level of reducing sugar can be obtained from
pre-treated T. suecica. Enzymatic saccharification of pre-treated T.
suecica biomass was optimised by changing temperature, pH, and
enzyme concentration to solid ratio ([E]/[S]). Highest conversion of
carbohydrate into reducing sugar of 95% amounted to reducing sugar
yield of 20 (wt%) from pre-treated T. suecica was obtained from
saccharification, at temperature: 40°C, pH: 4.5 and [E]/[S] of 0.1
after 72 h of incubation. Hydrolysate obtained from enzymatic
saccharification of pretreated T. suecica biomass was further
fermented into biobutanol using Clostridium saccharoperbutyliticum
as biocatalyst. The results from this study demonstrate a positive
prospect of application of dilute alkaline pre-treatment to enhance
enzymatic saccharification and biobutanol production from
microalgal biomass.
Abstract: Data envelopment analysis (DEA) has gained great popularity in environmental performance measurement because it can provide a synthetic standardized environmental performance index when pollutants are suitably incorporated into the traditional DEA framework. Since some of the environmental performance indicators cannot be controlled by companies managers, it is necessary to develop the model in a way that it could be applied when discretionary and/or non-discretionary factors were involved. In this paper, we present a semi-radial DEA approach to measuring environmental performance, which consists of non-discretionary factors. The model, then, has been applied on a real case.
Abstract: In the automotive industry test drives are being conducted
during the development of new vehicle models or as a part of
quality assurance of series-production vehicles. The communication
on the in-vehicle network, data from external sensors, or internal
data from the electronic control units is recorded by automotive
data loggers during the test drives. The recordings are used for fault
analysis. Since the resulting data volume is tremendous, manually
analysing each recording in great detail is not feasible.
This paper proposes to use machine learning to support domainexperts
by preventing them from contemplating irrelevant data and
rather pointing them to the relevant parts in the recordings. The
underlying idea is to learn the normal behaviour from available
recordings, i.e. a training set, and then to autonomously detect
unexpected deviations and report them as anomalies.
The one-class support vector machine “support vector data description”
is utilised to calculate distances of feature vectors. SVDDSUBSEQ
is proposed as a novel approach, allowing to classify subsequences
in multivariate time series data. The approach allows to
detect unexpected faults without modelling effort as is shown with
experimental results on recordings from test drives.
Abstract: With the advent of inexpensive 32 bit floating point digital signal processor-s availability in market, many computationally intensive algorithms such as Kalman filter becomes feasible to implement in real time. Dynamic simulation of a self excited DC motor using second order state variable model and implementation of Kalman Filter in a floating point DSP TMS320C6713 is presented in this paper with an objective to introduce and implement such an algorithm, for beginners. A fractional hp DC motor is simulated in both Matlab® and DSP and the results are included. A step by step approach for simulation of DC motor in Matlab® and “C" routines in CC Studio® is also given. CC studio® project file details and environmental setting requirements are addressed. This tutorial can be used with 6713 DSK, which is based on floating point DSP and CC Studio either in hardware mode or in simulation mode.
Abstract: Every organization is continually subject to new damages and threats which can be resulted from their operations or their goal accomplishment. Methods of providing the security of space and applied tools have been widely changed with increasing application and development of information technology (IT). From this viewpoint, information security management systems were evolved to construct and prevent reiterating the experienced methods. In general, the correct response in information security management systems requires correct decision making, which in turn requires the comprehensive effort of managers and everyone involved in each plan or decision making. Obviously, all aspects of work or decision are not defined in all decision making conditions; therefore, the possible or certain risks should be considered when making decisions. This is the subject of risk management and it can influence the decisions. Investigation of different approaches in the field of risk management demonstrates their progress from quantitative to qualitative methods with a process approach.
Abstract: We present a system that finds road boundaries and
constructs the virtual lane based on fusion data from a laser and a
monocular sensor, and detects forward vehicle position even in no lane
markers or bad environmental conditions. When the road environment
is dark or a lot of vehicles are parked on the both sides of the road, it is
difficult to detect lane and road boundary. For this reason we use
fusion of laser and vision sensor to extract road boundary to acquire
three dimensional data. We use parabolic road model to calculate road
boundaries which is based on vehicle and sensors state parameters and
construct virtual lane. And then we distinguish vehicle position in each
lane.
Abstract: Knowledge sharing in general and the contextual
access to knowledge in particular, still represent a key challenge in
the knowledge management framework. Researchers on semantic
web and human machine interface study techniques to enhance this
access. For instance, in semantic web, the information retrieval is
based on domain ontology. In human machine interface, keeping
track of user's activity provides some elements of the context that can
guide the access to information. We suggest an approach based on
these two key guidelines, whilst avoiding some of their weaknesses.
The approach permits a representation of both the context and the
design rationale of a project for an efficient access to knowledge. In
fact, the method consists of an information retrieval environment
that, in the one hand, can infer knowledge, modeled as a semantic
network, and on the other hand, is based on the context and the
objectives of a specific activity (the design). The environment we
defined can also be used to gather similar project elements in order to
build classifications of tasks, problems, arguments, etc. produced in a
company. These classifications can show the evolution of design
strategies in the company.
Abstract: In ad hoc networks, the main issue about designing of protocols is quality of service, so that in wireless sensor networks the main constraint in designing protocols is limited energy of sensors. In fact, protocols which minimize the power consumption in sensors are more considered in wireless sensor networks. One approach of reducing energy consumption in wireless sensor networks is to reduce the number of packages that are transmitted in network. The technique of collecting data that combines related data and prevent transmission of additional packages in network can be effective in the reducing of transmitted packages- number. According to this fact that information processing consumes less power than information transmitting, Data Aggregation has great importance and because of this fact this technique is used in many protocols [5]. One of the Data Aggregation techniques is to use Data Aggregation tree. But finding one optimum Data Aggregation tree to collect data in networks with one sink is a NP-hard problem. In the Data Aggregation technique, related information packages are combined in intermediate nodes and form one package. So the number of packages which are transmitted in network reduces and therefore, less energy will be consumed that at last results in improvement of longevity of network. Heuristic methods are used in order to solve the NP-hard problem that one of these optimization methods is to solve Simulated Annealing problems. In this article, we will propose new method in order to build data collection tree in wireless sensor networks by using Simulated Annealing algorithm and we will evaluate its efficiency whit Genetic Algorithm.
Abstract: This paper presents the region based segmentation method for ultrasound images using local statistics. In this segmentation approach the homogeneous regions depends on the image granularity features, where the interested structures with dimensions comparable to the speckle size are to be extracted. This method uses a look up table comprising of the local statistics of every pixel, which are consisting of the homogeneity and similarity bounds according to the kernel size. The shape and size of the growing regions depend on this look up table entries. The algorithms are implemented by using connected seeded region growing procedure where each pixel is taken as seed point. The region merging after the region growing also suppresses the high frequency artifacts. The updated merged regions produce the output in formed of segmented image. This algorithm produces the results that are less sensitive to the pixel location and it also allows a segmentation of the accurate homogeneous regions.
Abstract: Knowledge development in companies relies on
knowledge-intensive business processes, which are characterized by
a high complexity in their execution, weak structuring,
communication-oriented tasks and high decision autonomy, and often the need for creativity and innovation. A foundation of knowledge development is provided, which is based on a new conception of
knowledge and knowledge dynamics. This conception consists of a three-dimensional model of knowledge with types, kinds and qualities. Built on this knowledge conception, knowledge dynamics is
modeled with the help of general knowledge conversions between
knowledge assets. Here knowledge dynamics is understood to cover
all of acquisition, conversion, transfer, development and usage of
knowledge. Through this conception we gain a sound basis for
knowledge management and development in an enterprise. Especially
the type dimension of knowledge, which categorizes it according to
its internality and externality with respect to the human being, is crucial for enterprise knowledge management and development,
because knowledge should be made available by converting it to
more external types.
Built on this conception, a modeling approach for knowledgeintensive
business processes is introduced, be it human-driven,e-driven or task-driven processes. As an example for this approach, a model of the creative activity for the renewal planning of
a product is given.