Coupled Multifield Analysis of Piezoelectrically Actuated Microfluidic Device for Transdermal Drug Delivery Applications

In this paper, design, fabrication and coupled multifield analysis of hollow out-of-plane silicon microneedle array with piezoelectrically actuated microfluidic device for transdermal drug delivery (TDD) applications is presented. The fabrication process of silicon microneedle array is first done by series of combined isotropic and anisotropic etching processes using inductively coupled plasma (ICP) etching technology. Then coupled multifield analysis of MEMS based piezoelectrically actuated device with integrated 2×2 silicon microneedle array is presented. To predict the stress distribution and model fluid flow in coupled field analysis, finite element (FE) and computational fluid dynamic (CFD) analysis using ANSYS rather than analytical systems has been performed. Static analysis and transient CFD analysis were performed to predict the fluid flow through the microneedle array. The inlet pressure from 10 kPa to 150 kPa was considered for static CFD analysis. In the lumen region fluid flow rate 3.2946 μL/min is obtained at 150 V for 2×2 microneedle array. In the present study the authors have performed simulation of structural, piezoelectric and CFD analysis on three dimensional model of the piezoelectrically actuated mcirofluidic device integrated with 2×2 microneedle array.

Dissolution of Solid Particles in Liquids: A Shrinking Core Model

The dissolution of spherical particles in liquids is analyzed dynamically. Here, we consider the case the dissolution of solute yields a solute-free solid phase in the outer portion of a particle. As dissolution proceeds, the interface between the undissolved solid phase and the solute-free solid phase moves towards the center of the particle. We assume that there exist two resistances for the diffusion of solute molecules: the resistance due to the solute-free portion of the particle and that due to a surface layer near solid-liquid interface. In general, the equation governing the dynamic behavior of dissolution needs to be solved numerically. However, analytical expressions for the temporal variation of the size of the undissoved portion of a particle and the variation of dissolution time can be obtained in some special cases. The present analysis takes the effect of variable bulk solute concentration on dissolution into account.

Application of Java-based Pointcuts in Aspect Oriented Programming (AOP) for Data Race Detection

Wide applicability of concurrent programming practices in developing various software applications leads to different concurrency errors amongst which data race is the most important. Java provides greatest support for concurrent programming by introducing various concurrency packages. Aspect oriented programming (AOP) is modern programming paradigm facilitating the runtime interception of events of interest and can be effectively used to handle the concurrency problems. AspectJ being an aspect oriented extension to java facilitates the application of concepts of AOP for data race detection. Volatile variables are usually considered thread safe, but they can become the possible candidates of data races if non-atomic operations are performed concurrently upon them. Various data race detection algorithms have been proposed in the past but this issue of volatility and atomicity is still unaddressed. The aim of this research is to propose some suggestions for incorporating certain conditions for data race detection in java programs at the volatile fields by taking into account support for atomicity in java concurrency packages and making use of pointcuts. Two simple test programs will demonstrate the results of research. The results are verified on two different Java Development Kits (JDKs) for the purpose of comparison.

A New Condition for Conflicting Bifuzzy Sets Based On Intuitionistic Evaluation

Fuzzy sets theory affirmed that the linguistic value for every contraries relation is complementary. It was stressed in the intuitionistic fuzzy sets (IFS) that the conditions for contraries relations, which are the fuzzy values, cannot be greater than one. However, complementary in two contradict phenomena are not always true. This paper proposes a new idea condition for conflicting bifuzzy sets by relaxing the condition of intuitionistic fuzzy sets. Here, we will critically forward examples using triangular fuzzy number in formulating a new condition for conflicting bifuzzy sets (CBFS). Evaluation of positive and negative in conflicting phenomena were calculated concurrently by relaxing the condition in IFS. The hypothetical illustration showed the applicability of the new condition in CBFS for solving non-complement contraries intuitionistic evaluation. This approach can be applied to any decision making where conflicting is very much exist.

Improvement of Overall Equipment Effectiveness through Total Productive Maintenance

Frequent machine breakdowns, low plant availability and increased overtime are a great threat to a manufacturing plant as they increase operating costs of an industry. The main aim of this study was to improve Overall Equipment Effectiveness (OEE) at a manufacturing company through the implementation of innovative maintenance strategies. A case study approach was used. The paper focuses on improving the maintenance in a manufacturing set up using an innovative maintenance regime mix to improve overall equipment effectiveness. Interviews, reviewing documentation and historical records, direct and participatory observation were used as data collection methods during the research. Usually production is based on the total kilowatt of motors produced per day. The target kilowatt at 91% availability is 75 Kilowatts a day. Reduced demand and lack of raw materials particularly imported items are adversely affecting the manufacturing operations. The company had to reset its targets from the usual figure of 250 Kilowatt per day to mere 75 per day due to lower availability of machines as result of breakdowns as well as lack of raw materials. The price reductions and uncertainties as well as general machine breakdowns further lowered production. Some recommendations were given. For instance, employee empowerment in the company will enhance responsibility and authority to improve and totally eliminate the six big losses. If the maintenance department is to realise its proper function in a progressive, innovative industrial society, then its personnel must be continuously trained to meet current needs as well as future requirements. To make the maintenance planning system effective, it is essential to keep track of all the corrective maintenance jobs and preventive maintenance inspections. For large processing plants these cannot be handled manually. It was therefore recommended that the company implement (Computerised Maintenance Management System) CMMS.

Vacuum Membrane Distillation for Desalination of Ground Water by using Flat Sheet Membrane

The possibility of producing drinking water from brackish ground water using Vacuum membrane distillation (VMD) process was studied. It is a rising technology for seawater or brine desalination process. The process simply consists of a flat sheet hydrophobic micro porous PTFE membrane and diaphragm vacuum pump without a condenser for the water recovery or trap. In this work, VMD performance was investigated for aqueous NaCl solution and natural ground water. The influence of operational parameters such as feed flow rate (30 to 55 l/h), feed temperature (313 to 333 K), feed salt concentration (5000 to 7000 mg/l) and permeate pressure (1.5 to 6 kPa) on the membrane distillation (MD) permeation flux have been investigated. The maximum flux reached to 28.34 kg/m2 h at feed temperature, 333 K; vacuum pressure, 1.5 kPa; feed flow rate, 55 l/h and feed salt concentration, 7000 mg/l. The negligible effects in the reduction of permeate flux found over 150 h experimental run for salt water. But for the natural ground water application over 75 h, scale deposits observed on the membrane surface and 29% reduction in the permeate flux over 75 h. This reduction can be eliminated by acidification of feed water. Hence, promote the research attention in apply of VMD for the ground water purification over today-s conventional RO operation.

Sericin Film: Influence of Concentration on its Physical Properties

Silk sericin (SS) is a glue-like protein from silkworm cocoon. With its outstanding moisturization and activation collagen synthesis properties, silk protein is applied for wound healing. Since wound dressing in film preparation can facilitate patients- convenience and reduce risk of wound contraction, SS and polyvinyl alcohol (PVA) films were prepared with various concentrations of SS. Their physical properties such as surface density, light transmission, protein dissolution and tensile modulus were investigated. The results presented that 3% SS with 2% PVA is the best ingredient for SS film forming.

Comparative Analysis of Diversity and Similarity Indices with Special Relevance to Vegetations around Sewage Drains

Indices summarizing community structure are used to evaluate fundamental community ecology, species interaction, biogeographical factors, and environmental stress. Some of these indices are insensitive to gross community changes induced by contaminants of pollution. Diversity indices and similarity indices are reviewed considering their ecological application, both theoretical and practical. For some useful indices, empirical equations are given to calculate the expected maximum value of the indices to which the observed values can be related at any combination of sample sizes at the experimental sites. This paper examines the effects of sample size and diversity on the expected values of diversity indices and similarity indices, using various formulae. It has been shown that all indices are strongly affected by sample size and diversity. In some indices, this influence is greater than the others and an attempt has been made to deal with these influences.

Effects of Temperature on Resilient Modulus of Dense Asphalt Mixtures Incorporating Steel Slag Subjected to Short Term Oven Ageing

As the resources for naturally occurring aggregates diminished at an ever increasing rate, researchers are keen to utilize recycled materials in road construction in harmony with sustainable development. Steel slag, a waste product from the steel making industry, is one of the recycled materials reported to exhibit great potential to replace naturally occurring aggregates in asphalt mixtures. This paper presents the resilient modulus properties of steel slag asphalt mixtures subjected to short term oven ageing (STOA). The resilient modulus test was carried out to evaluate the stiffness of asphalt mixtures at 10ºC, 25ºC and 40ºC. Previous studies showed that stiffness changes in asphalt mixture played an important role in inflicting pavement distress particularly cracking and rutting that are common at low and high temperatures respectively. Temperature was found to significantly influence the resilient modulus of asphalt mixes. The resilient modulus of the asphalt specimens tested decreased by more than 90% when the test temperature increased from 10°C to 40°C.

Web Service Security Method To SOA Development

Web services provide significant new benefits for SOAbased applications, but they also expose significant new security risks. There are huge number of WS security standards and processes. At present, there is still a lack of a comprehensive approach which offers a methodical development in the construction of secure WS-based SOA. Thus, the main objective of this paper is to address this needs, presenting a comprehensive method for Web Services Security guaranty in SOA. The proposed method defines three stages, Initial Security Analysis, Architectural Security Guaranty and WS Security Standards Identification. These facilitate, respectively, the definition and analysis of WS-specific security requirements, the development of a WS-based security architecture and the identification of the related WS security standards that the security architecture must articulate in order to implement the security services.

Determinants of Capital Structure in Malaysia Electrical and Electronic Sector

Capital structure is one of the most important financial decisions in corporate financing strategy. It involves the choice of debt and equity level in financing a company-s operations. This study aims to investigate whether the capital structure choice of Malaysian electrical and electronic manufacturing companies that are listed in the Bursa Malaysia can be explained by factors that have been found by most studies as dominant determinants of capital structure (company size, profitability, asset tangibility, liquidity and growth). Using debt ratio as the proxy for capital structure and applying pooled ordinary least square multiple regression estimation, the results showed that on average, Malaysian electrical and electronic manufacturing companies used less debt in funding their business operations. The findings also showed that size and asset tangibility has a significant positive relationship with debt level, while liquidity has a negative significant relationship with leverage.

Terminal Velocity of a Bubble Rise in a Liquid Column

As it is known, buoyancy and drag forces rule bubble's rise velocity in a liquid column. These forces are strongly dependent on fluid properties, gravity as well as equivalent's diameter. This study reports a set of bubble rising velocity experiments in a liquid column using water or glycerol. Several records of terminal velocity were obtained. The results show that bubble's rise terminal velocity is strongly dependent on dynamic viscosity effect. The data set allowed to have some terminal velocities data interval of 8.0 ? 32.9 cm/s with Reynolds number interval 1.3 -7490. The bubble's movement was recorded with a video camera. The main goal is to present an original set data and results that will be discussed based on two-phase flow's theory. It will also discussed, the prediction of terminal velocity of a single bubble in liquid, as well as the range of its applicability. In conclusion, this study presents general expressions for the determination of the terminal velocity of isolated gas bubbles of a Reynolds number range, when the fluid proprieties are known.

Does the Polysemic Nature of Energy Security Make it a 'Wicked' Problem?

Governments around the world are expending considerable time and resources framing strategies and policies to deliver energy security. The term 'energy security' has quietly slipped into the energy lexicon without any meaningful discourse about its meaning or assumptions. An examination of explicit and inferred definitions finds that the concept is inherently slippery because it is polysemic in nature having multiple dimensions and taking on different specificities depending on the country (or continent), timeframe or energy source to which it is applied. But what does this mean for policymakers? Can traditional policy approaches be used to address the problem of energy security or does its- polysemic qualities mean that it should be treated as a 'wicked' problem? To answer this question, the paper assesses energy security against nine commonly cited characteristics of wicked policy problems and finds strong evidence of 'wickedness'.

MNECLIB2 – A Classical Music Digital Library

Lately there has been a significant boost of interest in music digital libraries, which constitute an attractive area of research and development due to their inherent interesting issues and challenging technical problems, solutions to which will be highly appreciated by enthusiastic end-users. We present here a DL that we have developed to support users in their quest for classical music pieces within a particular collection of 18,000+ audio recordings. To cope with the early DL model limitations, we have used a refined socio-semantic and contextual model that allows rich bibliographic content description, along with semantic annotations, reviewing, rating, knowledge sharing etc. The multi-layered service model allows incorporation of local and distributed information, construction of rich hypermedia documents, expressing the complex relationships between various objects and multi-dimensional spaces, agents, actors, services, communities, scenarios etc., and facilitates collaborative activities to offer to individual users the needed collections and services.

Numerical Investigation of Instabilities in Free Shear Layer Produced by NS-DBD Actuator

A numerical investigation of the effects of nanosecond barrier discharge on the stability of a two-dimensional free shear layer is performed. The computations are carried out using a compressible Navier-Stokes algorithm coupled with a thermodynamic model of the discharge. The results show that significant increases in the shear layer-s momentum thickness and Reynolds stresses occur due to actuation. Dependence on both frequency and amplitude of actuation are considered, and a comparison is made of the computed growth rates with those predicted by linear stability theory. Amplitude and frequency ranges for the efficient promotion of shear-layer instabilities are identified.

Climatic Factors Affecting on Influenza Casesin Nakhon Si Thammarat

This study investigated the climatic factors associated with Influenza incidence in Nakhon Si Thammarat, Southern Thailand. Climatic factors comprised of the amount of rainfall, percent of rainy days, relative humidity, wind speed, maximum, minimum temperatures and temperature difference. A multiple stepwise regression technique was used to fit the statistical model. The result showed that the temperature difference and percent of rainy days were positively associated with Influenza incidence in Nakhon Si Thammarat.

Motion Control of TUAV having Eight Rotors for Enhanced Situational Awareness

This paper focuses on a critical component of the situational awareness (SA), the control of autonomous vertical flight for tactical unmanned aerial vehicle (TUAV). With the SA strategy, we proposed a two stage flight control procedure using two autonomous control subsystems to address the dynamics variation and performance requirement difference in initial and final stages of flight trajectory for a nontrivial nonlinear eight-rotor helicopter model. This control strategy for chosen model of mini-TUAV has been verified by simulation of hovering maneuvers using software package Simulink and demonstrated good performance for fast stabilization of engines in hovering, consequently, fast SA with economy in energy of batteries can be asserted during search-andrescue operations.

Improving the Elder-s Quality of Life with Smart Television Based Services

The increasing number of senior population gradually causes to demand the use of information and communication technology for their satisfactory lives. This paper presents the development of an integrated TV based system which offers an opportunity to provide value added services to a large number of elderly citizens, and thus helps improve their quality of life. The design philosophy underlying this paper is to fulfill both technological and human aspects. The balance between these two dimensions has been currently stressed as a crucial element for the design of usable systems in real use, particularly to the elderly who have physical and mental decline. As the first step to achieve it, we have identified human and social factors that affect the elder-s quality of life by a literature review, and based on them, build four fundamental services: information, healthcare, learning and social network services. Secondly, the system architecture, employed technologies and the elderly-friendly system design considerations are presented. This reflects technological and human perspectives in terms of the system design. Finally, we describe some scenarios that illustrate the potentiality of the proposed system to improve elderly people-s quality of life.

Thermodynamic Optimization of Turboshaft Engine using Multi-Objective Genetic Algorithm

In this paper multi-objective genetic algorithms are employed for Pareto approach optimization of ideal Turboshaft engines. In the multi-objective optimization a number of conflicting objective functions are to be optimized simultaneously. The important objective functions that have been considered for optimization are specific thrust (F/m& 0), specific fuel consumption ( P S ), output shaft power 0 (& /&) shaft W m and overall efficiency( ) O η . These objectives are usually conflicting with each other. The design variables consist of thermodynamic parameters (compressor pressure ratio, turbine temperature ratio and Mach number). At the first stage single objective optimization has been investigated and the method of NSGA-II has been used for multiobjective optimization. Optimization procedures are performed for two and four objective functions and the results are compared for ideal Turboshaft engine. In order to investigate the optimal thermodynamic behavior of two objectives, different set, each including two objectives of output parameters, are considered individually. For each set Pareto front are depicted. The sets of selected decision variables based on this Pareto front, will cause the best possible combination of corresponding objective functions. There is no superiority for the points on the Pareto front figure, but they are superior to any other point. In the case of four objective optimization the results are given in tables.

Strategies for Connectivity Configuration to Access e-Learning Resources: Case of Rural Secondary Schools in Tanzania

In response to address different development challenges, Tanzania is striving to achieve its fourth attribute of the National Development Vision, i.e. to have a well educated and learned society by the year 2025. One of the most cost effective methods that can reach a large part of the society in a short time is to integrate ICT in education through e-learning initiatives. However, elearning initiatives are challenged by limited or lack of connectivity to majority of secondary schools, especially those in rural and remote areas. This paper has explores the possibility for rural secondary school to access online e-Learning resources from a centralized e- Learning Management System (e-LMS). The scope of this paper is limited to schools that have computers irrespective of internet connectivity, resulting in two categories schools; those with internet access and those without. Different connectivity configurations have been proposed according to the ICT infrastructure status of the respective schools. However, majority of rural secondary schools in Tanzania have neither computers nor internet connection. Therefore this is a challenge to be addressed for the disadvantaged schools to benefit from e-Learning initiatives.