Abstract: This study has investigated the antidiabetic and
antioxidant potential of Pseudovaria macrophylla bark extract on
streptozotocin–nicotinamide induced type 2 diabetic rats. LCMSQTOF
and NMR experiments were done to determine the chemical
composition in the methanolic bark extract. For in vivo experiments,
the STZ (60 mg/kg/b.w, 15 min after 120 mg/kg/1 nicotinamide, i.p.)
induced diabetic rats were treated with methanolic extract of
Pseuduvaria macrophylla (200 and 400 mg/kg·bw) and
glibenclamide (2.5 mg/kg) as positive control respectively.
Biochemical parameters were assayed in the blood samples of all
groups of rats. The pro-inflammatory cytokines, antioxidant status
and plasma transforming growth factor βeta-1 (TGF-β1) were
evaluated. The histological study of the pancreas was examined and
its expression level of insulin was observed by
immunohistochemistry. In addition, the expression of glucose
transporters (GLUT 1, 2 and 4) were assessed in pancreas tissue by
western blot analysis. The outcomes of the study displayed that the
bark methanol extract of Pseuduvaria macrophylla has potentially
normalized the elevated blood glucose levels and improved serum
insulin and C-peptide levels with significant increase in the
antioxidant enzyme, reduced glutathione (GSH) and decrease in the
level of lipid peroxidation (LPO). Additionally, the extract has
markedly decreased the levels of serum pro-inflammatory cytokines
and transforming growth factor beta-1 (TGF-β1). Histopathology
analysis demonstrated that Pseuduvaria macrophylla has the
potential to protect the pancreas of diabetic rats against peroxidation
damage by downregulating oxidative stress and elevated
hyperglycaemia. Furthermore, the expression of insulin protein,
GLUT-1, GLUT-2 and GLUT-4 in pancreatic cells was enhanced.
The findings of this study support the anti-diabetic claims of
Pseudovaria macrophylla bark.
Abstract: The design of technological procedures for
manufacturing certain products demands the definition and
optimization of technological process parameters. Their
determination depends on the model of the process itself and its
complexity. Certain processes do not have an adequate mathematical
model, thus they are modeled using heuristic methods. First part of
this paper presents a state of the art of using soft computing
techniques in manufacturing processes from the perspective of
applicability in modern CAx systems. Methods of artificial
intelligence which can be used for this purpose are analyzed. The
second part of this paper shows some of the developed models of
certain processes, as well as their applicability in the actual
calculation of parameters of some technological processes within the
design system from the viewpoint of productivity.
Abstract: Abstract–The objectives of the current study are to determine the
prevalence, etiological agents, drug susceptibility pattern and plasmid
profile of Acinetobacter baumannii isolates from Hospital-Acquired
Infections (HAI) at Community Hospital, Al Jouf Province, Saudi
Arabia. A total of 1890 patients had developed infection during
hospital admission and were included in the study. Among those who
developed nosocomial infections, 15(9.4), 10(2.7) and 118 (12.7) had
respiratory tract infection (RTI), blood stream infections (BSI) and
urinary tract (UTI) respectively. A total of 268 bacterial isolates were
isolated from nosocomial infection. S. aureus was reported in 23.5%
for of the total isolates followed by Klebsiella pneumoniae (17.5%), E.
coli (17.2%), P. aeruginosa (11.9%), coagulase negative
staphylococcus (9%), A. baumannii (7.1%), Enterobacter spp.
(3.4%), Citrobacter freundii (3%), Proteus mirabilis (2.6%), and
Proteus vulgaris and Enterococcous faecalis (0.7%). Isolated
organisms are multi-drug resistant, predominantly Gram-positive
pathogens with a high incidence of methicillin-resistant S. aureus,
extended spectrum beta lactamase and vancomycin resistant
enterococci organisms. The RFLP (Fragment Length Polymorphisms)
patterns of plasmid preparations from isolated A. baumannii isolates
had altered RFLP patterns, possibly due to the presence of plasmid(s).
Five A. baumannii isolates harbored plasmids all of which were not
less than 2.71kbp in molecular weight. Hence, it showed that the gene
coding for the isolates were located on the plasmid DNA while the
remaining isolates which have no plasmid might showed gene coding
for antibiotic resistance being located on chromosomal DNA.
Nosocomial infections represent a current problem in Community
Hospital, Al Jouf Province, Saudi Arabia. Problems associated with
SSI include infection with multidrug resistant pathogens which are
difficult to treat and are associated with increased mortality.
Abstract: We consider a network of two M/M/1 parallel queues having the same poisonnian arrival stream with rate λ. Upon his arrival to the system a customer heads to the shortest queue and stays until being served. If the two queues have the same length, an arriving customer chooses one of the two queues with the same probability. Each duration of service in the two queues is an exponential random variable with rate μ and no jockeying is permitted between the two queues. A new numerical method, based on linear programming and convex optimization, is performed for the computation of the steady state solution of the system.
Abstract: The Corporate Social Responsibility (CSR) performance has garnered significant interest during the last two decades as numerous methodologies are proposed by Social Responsible Investment (SRI) indexes. The weight of each indicator is a crucial component of the CSR measurement procedures. Based on a previous study, the appropriate weight of each proposed indicator for the Greek telecommunication sector is specified using the rank reciprocal weighting. The Kendall-s Coefficient of Concordance and Spearman Correlation Coefficient non-parametric tests are adopted to determine the level of consensus among the experts concerning the importance rank of indicators. The results show that there is no consensus regarding the rank of indicators in most of stakeholders- domains. The equal weight for all indicators could be proposed as a solution for the lack of consensus among the experts. The study recommends three different equations concerning the adopted weight approach.
Abstract: This paper describes a three-dimensional thermal
model of the current path included in the low voltage power circuit
breakers. The model can be used to analyse the thermal behaviour of
the current path during both steady-state and transient conditions.
The current path lengthwise temperature distribution and timecurrent
characteristic of the terminal connections of the power circuit
breaker have been obtained. The influence of the electric current and
voltage drop on main electric contact of the circuit breaker has been
investigated. To validate the three-dimensional thermal model, some
experimental tests have been done. There is a good correlation
between experimental and simulation results.
Abstract: The intention of this paper is, to help the user of evolutionary algorithms to adapt them easier to their problem at hand. For a lot of problems in the technical field it is not necessary to reach an optimum solution, but to reach a good solution in time. In many cases the solution is undetermined or there doesn-t exist a method to determine the solution. For these cases an evolutionary algorithm can be useful. This paper intents to give the user rules of thumb with which it is easier to decide if the problem is suitable for an evolutionary algorithm and how to design them.
Abstract: One of Effective parameters on the performance of linear induction motors is number of poles which must be selected and optimized to increase power efficiency and motor performance significantly. In this paper a double-sided linear induction motor with different poles number by using MAXWELL3D software is designed and with finite element method is analyzed electromagnetically. Then for dynamic simulation, linear motor by using MATLAB software is simulated. The results show that by adding poles number, system time response is increased and motor after more time reaches to steady state. Also propulsion force of motor is increased.
Abstract: The special and unique advantages of explosive
forming, has developed its use in different industries. Considering the
important influence of improving the current explosive forming
techniques on increasing the efficiency and control over the
explosive forming procedure, the effects of air and water as the
energy-conveying medium, and also their differences will be
illustrated in this paper. Hence, a large number of explosive forming
tests have been conducted on two sizes of thin walled cylindrical
shells by using air and water as the working medium. Comparative
diagrams of the maximum radial deflection of work-pieces of the
same size, as a function of the scaled distance, show that for the
points with the same values of scaled distance, the maximum radial
deformation caused by the under water explosive loading is 4 to 5
times more than the deflection of the shells under explosive forming,
while using air. Results of this experimental research have also been
compared with other studies which show that using water as the
energy conveying media increases the efficiency up to 4.8 times. The
effect of the media on failure modes of the shells, and the necking
mechanism of the walls of the specimens, while being explosively
loaded, are also discussed in this issue. Measuring the tested
specimens shows that, the increase in the internal volume has been
accompanied by necking of the walls, which finally results in the
radial rupture of the structure.
Abstract: The rapidly increasing costs of power line extensions
and fossil fuel, combined with the desire to reduce carbon dioxide
emissions pushed the development of hybrid power system suited for
remote locations, the purpose in mind being that of autonomous local
power systems. The paper presents the suggested solution for a “high
penetration" hybrid power system, it being determined by the
location of the settlement and its “zero policy" on carbon dioxide
emissions. The paper focuses on the technical solution and the power
flow management algorithm of the system, taking into consideration
local conditions of development.
Abstract: The rapid adoption of Internet has turned the Millennial Teens- life like a lightning speed. Empirical evidence has illustrated that Pathological Internet Use (PIU) among them ensure long-term success to the market players in the children industry. However, it creates concerns among their care takers as it generates mental disorder among some of them. The purpose of this paper is to examine the determinants of PIU and identify its outcomes among urban Millennial Teens. It aims to develop a theoretical framework based on a modified Media System Dependency (MSD) Theory that integrates important systems and components that determine and resulted from PIU.
Abstract: Renewable energy sources have gained ultimate urgency due to the need of the preservation of the environment for a sustainable development. Pyrolysis is an ultimate promising process in the recycling and acquisition of precious chemicals from wastes. Here, the co-pyrolysis of hazelnut shell with ultra-high molecular weight polyethylene was carried out catalytically and noncatalytically at 500 and 650 ºC. Potassium dichromate was added in certain amounts to act as a catalyst. The liquid, solid and gas products quantities were determined by gravimetry. As a main result, remarkable increases in gasification were observed by using this catalyst for pure components and their blends especially at 650 ºC. The increase in gas product quantity was compensated mainly with the decreases in the solid products and additionally in some cases liquid products quantities. These observations may stem from mainly the activation of carbon-carbon bonds rather than carbon-hydrogen bonds via potassium dichromate. Also, the catalytic effect of potassium dichromate on HS: PEO and HS: UHMWPE co-pyrolysis was compared.
Abstract: The implicit block methods based on the backward
differentiation formulae (BDF) for the solution of stiff initial value
problems (IVPs) using variable step size is derived. We construct a
variable step size block methods which will store all the coefficients
of the method with a simplified strategy in controlling the step size
with the intention of optimizing the performance in terms of
precision and computation time. The strategy involves constant,
halving or increasing the step size by 1.9 times the previous step size.
Decision of changing the step size is determined by the local
truncation error (LTE). Numerical results are provided to support the
enhancement of method applied.
Abstract: The purpose of this article is to analyze the
degree of concentration in the banking market in EU member
states as well as to determine the impact of the length of EU
membership on the degree of concentration. In that sense
several analysis were conducted, specifically, panel analysis,
calculation of correlation coefficient and regression analysis of
the impact of the length of EU membership on the degree of
concentration. Panel analysis was conducted to determine
whether there is a similar trend of concentration in three
groups of countries - countries with a low, moderate and high
level of concentration. The conducted panel analysis showed
that in EU countries with a moderate level of concentration,
the level of concentration decreases. The calculation of
correlation showed that, to some extent, with other influential
factors, the length of EU membership negatively affects the
market concentration of the banking market. Using the
regression analysis for investigation of the influence of the
length of EU membership on the level of concentration in the
banking sector in a particular country, the results reveal that
there is a negative effect of the length in EU membership on
market concentration, although it is not significantly influential
variable.
Abstract: Delamination between layers in composite materials is a major structural failure. The delamination resistance is quantified by the critical strain energy release rate (SERR). The present investigation deals with the strain energy release rate of two woven fabric composites. Materials used are made of two types of glass fiber (360 gsm and 600 gsm) of plain weave and epoxy as matrix. The fracture behavior is studied using the mode I, double cantilever beam test and the mode II, end notched flexure test, in order to determine the energy required for the initiation and growth of an artificial crack. The delamination energy of these two materials is compared in order to study the effect of weave and reinforcement on mechanical properties. The fracture mechanism is also analyzed by means of scanning electron microscopy (SEM). It is observed that the plain weave fabric composite with lesser strand width has higher inter laminar fracture properties compared to the plain weave fabric composite with more strand width.
Abstract: Most often the contaminants are not taken seriously into consideration, and this behavior comes out directly from the lack of monitoring and professional reporting about pollution in the printing facilities in Serbia. The goal of planned and systematic ozone measurements in ambient air of the screen printing facilities in Novi Sad is to examine of its impact on the employees health, and to track trends in concentration. In this study, ozone concentrations were determined by using discontinuous and continuous method during the automatic and manual screen printing process. Obtained results indicates that the average concentrations of ozone measured during the automatic process were almost 3 to 28 times higher for discontinuous and 10 times higher for continuous method (1.028 ppm) compared to the values prescribed by OSHA. In the manual process, average concentrations of ozone were within prescribed values for discontinuous and almost 3 times higher for continuous method (0.299 ppm).
Abstract: Speckle noise affects all coherent imaging systems
including medical ultrasound. In medical images, noise suppression
is a particularly delicate and difficult task. A tradeoff between noise
reduction and the preservation of actual image features has to be made
in a way that enhances the diagnostically relevant image content.
Even though wavelets have been extensively used for denoising
speckle images, we have found that denoising using contourlets gives
much better performance in terms of SNR, PSNR, MSE, variance and
correlation coefficient. The objective of the paper is to determine the
number of levels of Laplacian pyramidal decomposition, the number
of directional decompositions to perform on each pyramidal level and
thresholding schemes which yields optimal despeckling of medical
ultrasound images, in particular. The proposed method consists of the
log transformed original ultrasound image being subjected to contourlet
transform, to obtain contourlet coefficients. The transformed
image is denoised by applying thresholding techniques on individual
band pass sub bands using a Bayes shrinkage rule. We quantify the
achieved performance improvement.
Abstract: This paper presents a novel approach for optimal
reconfiguration of radial distribution systems. Optimal
reconfiguration involves the selection of the best set of branches to
be opened, one each from each loop, such that the resulting radial
distribution system gets the desired performance. In this paper an
algorithm is proposed based on simple heuristic rules and identified
an effective switch status configuration of distribution system for the
minimum loss reduction. This proposed algorithm consists of two
parts; one is to determine the best switching combinations in all loops
with minimum computational effort and the other is simple optimum
power loss calculation of the best switching combination found in
part one by load flows. To demonstrate the validity of the proposed
algorithm, computer simulations are carried out on 33-bus system.
The results show that the performance of the proposed method is
better than that of the other methods.
Abstract: This research study the application of the immobilized
TiO2 layer and Cu-TiO2 layer on graphite substrate as a negative
electrode or anode for Li-ion battery. The titania layer was produced
through chemical bath deposition method, meanwhile Cu particles
were deposited electrochemically. A material can be used as an
electrode as it has capability to intercalates Li ions into its crystal
structure. The Li intercalation into TiO2/Graphite and Cu-
TiO2/Graphite were analyzed from the changes of its XRD pattern
after it was used as electrode during discharging process. The XRD
patterns were refined by Le Bail method in order to determine the
crystal structure of the prepared materials. A specific capacity and the
cycle ability measurement were carried out to study the performance
of the prepared materials as negative electrode of the Li-ion battery.
The specific capacity was measured during discharging process from
fully charged until the cut off voltage. A 300 was used as a load.
The result shows that the specific capacity of Li-ion battery with
TiO2/Graphite as negative electrode is 230.87 ± 1.70mAh.g-1 which is
higher than the specific capacity of Li-ion battery with pure graphite
as negative electrode, i.e 140.75 ±0.46mAh.g-1. Meanwhile
deposition of Cu onto TiO2 layer does not increase the specific
capacity, and the value even lower than the battery with
TiO2/Graphite as electrode. The cycle ability of the prepared battery
is only two cycles, due to the Li ribbon which was used as cathode
became fragile and easily broken.
Abstract: Cryptography, Image watermarking and E-banking are
filled with apparent oxymora and paradoxes. Random sequences are
used as keys to encrypt information to be used as watermark during
embedding the watermark and also to extract the watermark during
detection. Also, the keys are very much utilized for 24x7x365
banking operations. Therefore a deterministic random sequence is
very much useful for online applications. In order to obtain the same
random sequence, we need to supply the same seed to the generator.
Many researchers have used Deterministic Random Number
Generators (DRNGs) for cryptographic applications and Pseudo
Noise Random sequences (PNs) for watermarking. Even though,
there are some weaknesses in PN due to attacks, the research
community used it mostly in digital watermarking. On the other hand,
DRNGs have not been widely used in online watermarking due to its
computational complexity and non-robustness. Therefore, we have
invented a new design of generating DRNG using Pi-series to make it
useful for online Cryptographic, Digital watermarking and Banking
applications.