Abstract: Transcription factor p53 has a powerful tumor
suppressing function that is associated with many cancers. However,
p53 of the molecular weight was higher make the limitation across to
skin or cell membrane. Thymidine dinucleotide (pTT), an
oligonucleotide, can activate the p53 transcription factor. pTT is a
hydrophilic and negative charge oligonucleotide, which delivery in to
cell membrane need an appropriate carrier. The aim of this study was
to improve the bioavailability of the nucleotide fragment, thymidine
dinucleotide (pTT), using elasic liposome carriers to deliver the drug
into the skin. The study demonstrate that dioleoylphosphocholine
(DOPC) incorporated with sodium cholate at molar ratio 1:1 can
archived the particle size about 220 nm. This elastic liposome could
penetration through skin from stratum corneum to whole epidermis by
confocal laser scanning microscopy (CLSM). Moreover, we observed
the the slight increase in generation of p53 by western blot.
Abstract: Groundwater is one of the most important water
resources in Fars province. Based on this study, 95 percent of the
total annual water consumption in Fars is used for agriculture,
whereas the percentages for domestic and industrial uses are 4 and 1
percent, respectively. Population growth, urban and industrial
growth, and agricultural development in Fars have created a
condition of water stress. In this province, farmers and other users are
pumping groundwater faster than its natural replenishment rate,
causing a continuous drop in groundwater tables and depletion of this
resource. In this research variation of groundwater level, their effects
and ways to help control groundwater levels in aquifer of the Kavar-
Maharloo plains in Fars plain were evaluated .Excessive
exploitation of groundwater in this aquifer caused the groundwater
levels fall too fast or to unacceptable levels. The average drawdown
of the groundwater level in this plain were 17 meters during
1995 to 2006. The purpose of this study is to evaluate water level
changes in the Kavar-Maharloo Aquifer in the Fars province in order
to determine the areas of greatest depletion, the cause of depletion,
and predict the remaining life of the aquifer.
Abstract: Explosive forming is one of the unconventional
techniques in which, most commonly, the water is used as the
pressure transmission medium. One of the newest methods in
explosive forming is gas detonation forming which uses a normal
shock wave derived of gas detonation, to form sheet metals. For this
purpose a detonation is developed from the reaction of H2+O2
mixture in a long cylindrical detonation tube. The detonation wave
goes through the detonation tube and acts as a blast load on the steel
blank and forms it. Experimental results are compared with a finite
element model; and the comparison of the experimental and
numerical results obtained from strain, thickness variation and
deformed geometry is carried out. Numerical and experimental
results showed approximately 75 – 90 % similarity in formability of
desired shape. Also optimum percent of gas mixture obtained when
we mix 68% H2 with 32% O2.
Abstract: The Spiral development model has been used
successfully in many commercial systems and in a good number of
defense systems. This is due to the fact that cost-effective
incremental commitment of funds, via an analogy of the spiral model
to stud poker and also can be used to develop hardware or integrate
software, hardware, and systems. To support adaptive, semantic
collaboration between domain experts and knowledge engineers, a
new knowledge engineering process, called Spiral_OWL is proposed.
This model is based on the idea of iterative refinement, annotation
and structuring of knowledge base. The Spiral_OWL model is
generated base on spiral model and knowledge engineering
methodology. A central paradigm for Spiral_OWL model is the
concentration on risk-driven determination of knowledge engineering
process. The collaboration aspect comes into play during knowledge
acquisition and knowledge validation phase. Design rationales for the
Spiral_OWL model are to be easy-to-implement, well-organized, and
iterative development cycle as an expanding spiral.
Abstract: This paper describes the speed sensorless vector control method of the parallel connected induction motor drive fed by a single inverter. Speed and rotor fluxes of the induction motor are estimated by natural observer with load torque adaptation and adaptive rotor flux observer. The performance parameters speed and rotor fluxes are estimated from the measured terminal voltages and currents. Fourth order induction motor model is used and speed is considered as a parameter. The performance of the natural observer is similar to the conventional observer. The speed of an induction motor is estimated by MATLAB simulation under different speed and load conditions. Estimated values along with other measured states are used for closed loop control. The simulation results show that the natural observer is also effective for parallel connected induction motor drive.
Abstract: In this paper, we will generate the wreath product
11 12 M wrM using only two permutations. Also, we will show the
structure of some groups containing the wreath product 11 12 M wrM .
The structure of the groups founded is determined in terms of wreath
product k (M wrM ) wrC 11 12 . Some related cases are also included.
Also, we will show that 132K+1 S and 132K+1 A can be generated
using the wreath product k (M wrM ) wrC 11 12 and a transposition in
132K+1 S and an element of order 3 in 132K+1 A . We will also show
that 132K+1 S and 132K+1 A can be generated using the wreath
product 11 12 M wrM and an element of order k +1.
Abstract: There are many approaches proposed for solving
Sudoku puzzles. One of them is by modelling the puzzles as block
world problems. There have been three model for Sudoku solvers
based on this approach. Each model expresses Sudoku solver as
a parameterized multi agent systems. In this work, we propose a
new model which is an improvement over the existing models. This
paper presents the development of a Sudoku solver that implements
all the proposed models. Some experiments have been conducted to
determine the performance of each model.
Abstract: Recently, various services such as television and the
Internet have come to be received through various terminals.
However, we could gain greater convenience by receiving these
services through cellular phone terminals when we go out and then
continuing to receive the same services through a large screen digital
television after we have come home. However, it is necessary to go
through the same authentication processing again when using TVs
after we have come home. In this study, we have developed an
authentication method that enables users to switch terminals in
environments in which the user receives service from a server through
a terminal. Specifically, the method simplifies the authentication of
the server side when switching from one terminal to another terminal
by using previously authenticated information.
Abstract: The sensitivity of orifice plate metering to disturbed
flow (either asymmetric or swirling) is a subject of great concern to
flow meter users and manufacturers. The distortions caused by pipe
fittings and pipe installations upstream of the orifice plate are major
sources of this type of non-standard flows. These distortions can alter
the accuracy of metering to an unacceptable degree. In this work, a
multi-scale object known as metal foam has been used to generate a
predetermined turbulent flow upstream of the orifice plate. The
experimental results showed that the combination of an orifice plate
and metal foam flow conditioner is broadly insensitive to upstream
disturbances. This metal foam demonstrated a good performance in
terms of removing swirl and producing a repeatable flow profile
within a short distance downstream of the device. The results of using
a combination of a metal foam flow conditioner and orifice plate for
non-standard flow conditions including swirling flow and asymmetric
flow show this package can preserve the accuracy of metering up to
the level required in the standards.
Abstract: A computer model of Quantum Theory (QT) has been
developed by the author. Major goal of the computer model was
support and demonstration of an as large as possible scope of QT.
This includes simulations for the major QT (Gedanken-) experiments
such as, for example, the famous double-slit experiment.
Besides the anticipated difficulties with (1) transforming exacting
mathematics into a computer program, two further types of problems
showed up, namely (2) areas where QT provides a complete mathematical
formalism, but when it comes to concrete applications the
equations are not solvable at all, or only with extremely high effort;
(3) QT rules which are formulated in natural language and which do
not seem to be translatable to precise mathematical expressions, nor
to a computer program.
The paper lists problems in all three categories and describes also
the possible solutions or circumventions developed for the computer
model.
Abstract: In this work a new method for low complexity
image coding is presented, that permits different settings and great
scalability in the generation of the final bit stream. This coding
presents a continuous-tone still image compression system that
groups loss and lossless compression making use of finite arithmetic
reversible transforms. Both transformation in the space of color and
wavelet transformation are reversible. The transformed coefficients
are coded by means of a coding system in depending on a
subdivision into smaller components (CFDS) similar to the bit
importance codification. The subcomponents so obtained are
reordered by means of a highly configure alignment system
depending on the application that makes possible the re-configure of
the elements of the image and obtaining different importance levels
from which the bit stream will be generated. The subcomponents of
each importance level are coded using a variable length entropy
coding system (VBLm) that permits the generation of an embedded
bit stream. This bit stream supposes itself a bit stream that codes a
compressed still image. However, the use of a packing system on the
bit stream after the VBLm allows the realization of a final highly
scalable bit stream from a basic image level and one or several
improvement levels.
Abstract: The paper is intended to declare and apply ethics, i. e.
moral principles, rules in marketing environment. Ethical behavior of
selected pharmaceutical companies in the Slovak Republic is the
object of our research. The aim of our research is to determine
perception of ethical behavior of the pharmaceutical industry in
Slovakia by the medicine representatives in comparison with the
assessment of doctors and patients. The experimental sample
included 90 participants who were divided into three groups:
medicine representatives of the pharmaceutical companies (N=30),
doctors (N=30) and patients (N=30). The research method was a
Questionnaire of ethical behavior, created by us, that describes
individual areas included in the Code of ethics of the pharmaceutical
industry in Slovakia. The results showed influence of professional
status on ethical behavior perception, not gender. Higher perception
was indicated at patients rather than doctors and medicine
representatives.
Abstract: For higher order multiplications, a huge number of
adders or compressors are to be used to perform the partial product
addition. We have reduced the number of adders by introducing
special kind of adders that are capable to add five/six/seven bits per
decade. These adders are called compressors. Binary counter
property has been merged with the compressor property to develop
high order compressors. Uses of these compressors permit the
reduction of the vertical critical paths. A 16×16 bit multiplier has
been developed using these compressors. These compressors make
the multipliers faster as compared to the conventional design that
have been used 4-2 compressors and 3-2 compressors.
Abstract: The aim of the study was to follow changes of powervelocity
relationship in female volleyball players during an annual
training cycle. The study was conducted on eleven female volleyball
players: age 21.6±1.7 years, body height 177.9±4.7 cm, body mass
71.3±6.6 kg and training experience 8.6±3.3 years. Power–velocity
relationship was determined from five maximal 10-second
cycloergometer efforts with external loads equal: 2.5, 5.0, 7.5, 10.0
and 12.5% of body weight (BW) before (I) and after (II) the
preparatory period, after the first (III) and second (IV) competitive
season. The maximal power output increased from 9.30±0.85 W•kg–1
(I) to 9.50±0.96 W•kg–1 (II), 9.77±0.96 W•kg–1 (III) and 9.95±1.13
W•kg–1 (IV, p
Abstract: The present work presents a method of calculating the
ductility of rectangular sections of beams considering nonlinear
behavior of concrete and steel. This calculation procedure allows us
to trace the curvature of the section according to the bending
moment, and consequently deduce ductility. It also allowed us to
study the various parameters that affect the value of the ductility. A
comparison of the effect of maximum rates of tension steel, adopted
by the codes, ACI [1], EC8 [2] and RPA [3] on the value of the
ductility was made. It was concluded that the maximum rate of steels
permitted by the ACI [1] codes and RPA [3] are almost similar in
their effect on the ductility and too high. Therefore, the ductility
mobilized in case of an earthquake is low, the inverse of code EC8
[2]. Recommendations have been made in this direction.
Abstract: Soils are normally dried in either a convection oven or stove. Laboratory moisture content testing indicated that the typical drying durations for a convection oven were, 24 hours. The purpose of this study was to determine the accuracy and soil drying duration of both, moisture content and liquid limit using microwave radiation. The soils were tested with both, convection and microwave ovens. The convection oven was considered to produce the true values for both, natural moisture content and liquid limit of soils; it was, therefore, used as a basis for comparison for the results of the microwave ovens. The samples used in this study were obtained from different projects of Consulting Engineering Bureau of College of Engineering of Sulaimani University. These samples were collected from different locations and at the different depths and consist mostly of brown and light brown clay and silty clay. A total of 102 samples were prepared. 26 of them were tested for natural moisture determination, while the other 76 were used for liquid limits determination
Abstract: This paper aims to develop a NOx emission model of
an acid gas incinerator using Nelder-Mead least squares support
vector regression (LS-SVR). Malaysia DOE is actively imposing the
Clean Air Regulation to mandate the installation of analytical
instrumentation known as Continuous Emission Monitoring System
(CEMS) to report emission level online to DOE . As a hardware
based analyzer, CEMS is expensive, maintenance intensive and often
unreliable. Therefore, software predictive technique is often
preferred and considered as a feasible alternative to replace the
CEMS for regulatory compliance. The LS-SVR model is built based
on the emissions from an acid gas incinerator that operates in a LNG
Complex. Simulated Annealing (SA) is first used to determine the
initial hyperparameters which are then further optimized based on the
performance of the model using Nelder-Mead simplex algorithm.
The LS-SVR model is shown to outperform a benchmark model
based on backpropagation neural networks (BPNN) in both training
and testing data.
Abstract: Lighting upgrades involve relatively lower costs which
allow the benefits to be spread more widely than is possible with any
other energy efficiency measure. In order to popularize the adoption of
CFL in Taiwan, the authority proposes to implement a new energy efficient lamp comparative label system. The current study was
accordingly undertaken to investigate the factors affecting the performance and the deviation of actual and labeled performance of
commercially available integrated CFLs. In this paper, standard test
methods to determine the electrical and photometric performances of
CFL were developed based on CIE 84-1989 and CIE 60901-1987,
then 55 selected CFLs from market were tested. The results show that
with higher color temperature of CFLs lower efficacy are achieved. It
was noticed that the most packaging of CFL often lack the information of Color Rendering Index. Also, there was no correlation between
price and performance of the CFLs was indicated in this work. The results of this paper might help consumers to make more informed
CFL-purchasing decisions.
Abstract: The aim of the study was to evaluate the effect of
texturizers on the rheological properties of the apple mass and
desserts made from various raw materials. The apple varieties -
‘Antonovka’, ‘Baltais Dzidrais’, and ‘Zarja Alatau’ harvested in
Latvia, were used for the experiment. The apples were processed in a
blender unpeeled for obtaining a homogenous mass. The apple mass
was analyzed fresh and after storage at –18ºC. Both fresh and thawed
apple mass samples with added gelatin, xantan gum, and sodium
carboxymethylcellulose were whisked obtaining dessert. Pectin, pH
and soluble dry matter of the product were determined. Apparent
viscosity was measured using a rotational viscometer DV–III Ultra.
Pectin content in frozen apple mass decreased significantly (p
Abstract: Acute kidney injury (AKI) is a new worldwide public
health problem. A diagnosis of this disease using creatinine is still a
problem in clinical practice. Therefore, a measurement of biomarkers
responsible for AKI has received much attention in the past couple
years. Cytokine interleukin-18 (IL-18) was reported as one of the
early biomarkers for AKI. The most commonly used method to
detect this biomarker is an immunoassay. This study used a planar
platform to perform an immunoassay using fluorescence for
detection. In this study, anti-IL-18 antibody was immobilized onto a
microscope slide using a covalent binding method. Make-up samples
were diluted at the concentration between 10 to 1000 pg/ml to create
a calibration curve. The precision of the system was determined
using a coefficient of variability (CV), which was found to be less
than 10%. The performance of this immunoassay system was
compared with the measurement from ELISA.