Abstract: Cellular complexity stems from the interactions
among thousands of different molecular species. Thanks to the
emerging fields of systems and synthetic biology, scientists are
beginning to unravel these regulatory, signaling, and metabolic
interactions and to understand their coordinated action. Reverse
engineering of biological networks has has several benefits but a
poor quality of data combined with the difficulty in reproducing
it limits the applicability of these methods. A few years back,
many of the commonly used predictive algorithms were tested
on a network constructed in the yeast Saccharomyces cerevisiae
(S. cerevisiae) to resolve this issue. The network was a synthetic
network of five genes regulating each other for the so-called in
vivo reverse-engineering and modeling assessment (IRMA). The
network was constructed in S. cereviase since it is a simple and well
characterized organism. The synthetic network included a variety
of regulatory interactions, thus capturing the behaviour of larger
eukaryotic gene networks on a smaller scale. We derive a new set of
algorithms by solving a nonlinear optimization problem and show
how these algorithms outperform other algorithms on these datasets.
Abstract: Model Predictive Control (MPC) is increasingly being
proposed for real time applications and embedded systems. However
comparing to PID controller, the implementation of the MPC in
miniaturized devices like Field Programmable Gate Arrays (FPGA)
and microcontrollers has historically been very small scale due to its
complexity in implementation and its computation time requirement.
At the same time, such embedded technologies have become an
enabler for future manufacturing enterprises as well as a transformer
of organizations and markets. Recently, advances in microelectronics
and software allow such technique to be implemented in embedded
systems. In this work, we take advantage of these recent advances
in this area in the deployment of one of the most studied and
applied control technique in the industrial engineering. In fact in
this paper, we propose an efficient framework for implementation
of Generalized Predictive Control (GPC) in the performed STM32
microcontroller. The STM32 keil starter kit based on a JTAG interface
and the STM32 board was used to implement the proposed GPC
firmware. Besides the GPC, the PID anti windup algorithm was
also implemented using Keil development tools designed for ARM
processor-based microcontroller devices and working with C/Cµ
langage. A performances comparison study was done between both
firmwares. This performances study show good execution speed and
low computational burden. These results encourage to develop simple
predictive algorithms to be programmed in industrial standard hardware.
The main features of the proposed framework are illustrated
through two examples and compared with the anti windup PID
controller.
Abstract: This paper aims to develop a NOx emission model of
an acid gas incinerator using Nelder-Mead least squares support
vector regression (LS-SVR). Malaysia DOE is actively imposing the
Clean Air Regulation to mandate the installation of analytical
instrumentation known as Continuous Emission Monitoring System
(CEMS) to report emission level online to DOE . As a hardware
based analyzer, CEMS is expensive, maintenance intensive and often
unreliable. Therefore, software predictive technique is often
preferred and considered as a feasible alternative to replace the
CEMS for regulatory compliance. The LS-SVR model is built based
on the emissions from an acid gas incinerator that operates in a LNG
Complex. Simulated Annealing (SA) is first used to determine the
initial hyperparameters which are then further optimized based on the
performance of the model using Nelder-Mead simplex algorithm.
The LS-SVR model is shown to outperform a benchmark model
based on backpropagation neural networks (BPNN) in both training
and testing data.