Abstract: In molecular biology, microarray technology is widely and successfully utilized to efficiently measure gene activity. If working with less studied organisms, methods to design custom-made microarray probes are available. One design criterion is to select probes with minimal melting temperature variances thus ensuring similar hybridization properties. If the microarray application focuses on the investigation of metabolic pathways, it is not necessary to cover the whole genome. It is more efficient to cover each metabolic pathway with a limited number of genes. Firstly, an approach is presented which minimizes the overall melting temperature variance of selected probes for all genes of interest. Secondly, the approach is extended to include the additional constraints of covering all pathways with a limited number of genes while minimizing the overall variance. The new optimization problem is solved by a bottom-up programming approach which reduces the complexity to make it computationally feasible. The new method is exemplary applied for the selection of microarray probes in order to cover all fungal secondary metabolite gene clusters for Aspergillus terreus.
Abstract: The scientific achievements coming from molecular
biology depend greatly on the capability of computational
applications to analyze the laboratorial results. A comprehensive
analysis of an experiment requires typically the simultaneous study
of the obtained dataset with data that is available in several distinct
public databases. Nevertheless, developing a centralized access to
these distributed databases rises up a set of challenges such as: what
is the best integration strategy, how to solve nomenclature clashes,
how to solve database overlapping data and how to deal with huge
datasets. In this paper we present GeNS, a system that uses a simple and yet innovative approach to address several biological data integration issues. Compared with existing systems, the main
advantages of GeNS are related to its maintenance simplicity and to its coverage and scalability, in terms of number of supported
databases and data types. To support our claims we present the current use of GeNS in two concrete applications. GeNS currently contains more than 140 million of biological relations and it can be
publicly downloaded or remotely access through SOAP web services.
Abstract: This paper presents an algorithm to estimate the parameters of two closely spaced sinusoids, providing a frequency resolution that is more than 800 times greater than that obtained by using the Discrete Fourier Transform (DFT). The strategy uses a highly optimized grid search approach to accurately estimate frequency, amplitude and phase of both sinusoids, keeping at the same time the computational effort at reasonable levels. The proposed method has three main characteristics: 1) a high frequency resolution; 2) frequency, amplitude and phase are all estimated at once using one single package; 3) it does not rely on any statistical assumption or constraint. Potential applications to this strategy include the difficult task of resolving coincident partials of instruments in musical signals.
Abstract: Synthetic Aperture Radar (SAR) is an imaging radar form by taking full advantage of the relative movement of the antenna with respect to the target. Through the simultaneous processing of the radar reflections over the movement of the antenna via the Range Doppler Algorithm (RDA), the superior resolution of a theoretical wider antenna, termed synthetic aperture, is obtained. Therefore, SAR can achieve high resolution two dimensional imagery of the ground surface. In addition, two filtering steps in range and azimuth direction provide accurate enough result. This paper develops a simulation in which realistic SAR images can be generated. Also, the effect of velocity errors in the resulting image has also been investigated. Taking some velocity errors into account, the simulation results on the image resolution would be presented. Most of the times, algorithms need to be adjusted for particular datasets, or particular applications.
Abstract: This paper is concerned with the numerical minimization
of energy functionals in BV (
) (the space of bounded variation
functions) involving total variation for gray-scale 1-dimensional inpainting
problem. Applications are shown by finite element method
and discontinuous Galerkin method for total variation minimization.
We include the numerical examples which show the different recovery
image by these two methods.
Abstract: The purpose of Grid computing is to utilize
computational power of idle resources which are distributed in
different areas. Given the grid dynamism and its decentralize
resources, there is a need for an efficient scheduler for scheduling
applications. Since task scheduling includes in the NP-hard problems
various researches have focused on invented algorithms especially
the genetic ones. But since genetic is an inherent algorithm which
searches the problem space globally and does not have the efficiency
required for local searching, therefore, its combination with local
searching algorithms can compensate for this shortcomings. The aim
of this paper is to combine the genetic algorithm and GELS (GAGELS)
as a method to solve scheduling problem by which
simultaneously pay attention to two factors of time and number of
missed tasks. Results show that the proposed algorithm can decrease
makespan while minimizing the number of missed tasks compared
with the traditional methods.
Abstract: This paper introduces application of multi degree of freedom fuzzy(MDOFF) controller in permanent magnet (PM)drive system. The drive system model is developed for FO control. Simulation of the system is carried out to predict the performance at NL and under load,. The results indicate that application of MDOFF controller is effective for sensorless PM drive system.
Abstract: This paper describes the challenges on the requirements engineering for developing an enterprise applications in higher
education environment. The development activities include software implementation, maintenance, and enhancement and support for online
transaction processing and overnight batch processing.
Generally, an enterprise application for higher education environment
may include Student Information System (SIS), HR/Payroll system,
Financial Systems etc. By the way, there are so many challenges in
requirement engineering phases in order to provide two distinctive
services that are production processing support and systems
development.
Abstract: Fuzzy linear programming is an application of fuzzy set theory in linear decision making problems and most of these problems are related to linear programming with fuzzy variables. A convenient method for solving these problems is based on using of auxiliary problem. In this paper a new method for solving fuzzy variable linear programming problems directly using linear ranking functions is proposed. This method uses simplex tableau which is used for solving linear programming problems in crisp environment before.
Abstract: The Informational Infrastructures of small and medium-sized manufacturing enterprises are relatively poor, there are serious shortages of capitals which can be invested in informatization construction, computer hardware and software resources, and human resources. To address the informatization issue in small and medium-sized manufacturing enterprises, and enable them to the application of advanced management thinking and enhance their competitiveness, the paper establish a manufacturing-oriented small and medium-sized enterprises informatization platform based on the ASP business intelligence technology, which effectively improves the scientificity of enterprises decision and management informatization.
Abstract: Location-based services (LBS) exploit the known
location of a user to provide services dependent on their geographic
context and personalized needs [1].
The development and arrival of broadband mobile data networks
supported with mobile terminals equipped with new location
technologies like GPS have finally created opportunities for
implementation of LBS applications. But, from the other side,
collecting location information data in general raises privacy
concerns.
This paper presents results from two surveys of LBS acceptance in
Croatia. The first survey was administered on 181 students, and the
second extended survey involved pattern of 180 Croatian citizens.
We developed questionnaire which consists of descriptions of 15
different applications with scale which measures perceptions and
attitudes of users towards these applications.
We report the results to identify potential commercial applications
for LBS in B2C segment. Our findings suggest that some types of
applications like emergency&safety services and navigation have
significantly higher rate of acceptance than other types.
Abstract: The purpose of this paper is to shed light on the
controversial subject of tax incentives to promote regional
development. Although extensive research has been conducted, a
review of the literature gives an inconclusive answer to whether
economic incentives are effective. One reason is the fact that for
some researchers “effective" means the significant location of new
firms in targeted areas, while for others the creation of jobs
regardless if new firms are arriving in a significant fashion. We
present this dichotomy by analyzing a tax incentive program via both
alternatives: location and job creation. The contribution of the paper
is to inform policymakers about the potential opportunities and
pitfalls when designing incentive strategies. This is particularly
relevant, given that both the US and Europe have been promoting
incentives as a tool for regional economic development.
Abstract: In aerospace applications, interactions of airflow with
aircraft structures can result in undesirable structural deformations.
This structural deformation in turn, can be predicted if the natural
modes of the structure are known. This can be achieved through
conventional modal testing that requires a known excitation force in
order to extract these dynamic properties. This technique can be
experimentally complex because of the need for artificial excitation
and it is also does not represent actual operational condition. The
current work presents part of research work that address the practical
implementation of operational modal analysis (OMA) applied to a
cantilevered hybrid composite plate employing single contactless
sensing system via laser vibrometer. OMA technique extracts the
modal parameters based only on the measurements of the dynamic
response. The OMA results were verified with impact hammer modal
testing and good agreement was obtained.
Abstract: In this paper we present modeling and simulation for
physical vapor deposition for metallic bipolar plates. In the models
we discuss the application of different models to simulate the
transport of chemical reactions of the gas species in the gas chamber.
The so called sputter process is an extremely sensitive process to
deposit thin layers to metallic plates. We have taken into account
lower order models to obtain first results with respect to the gas
fluxes and the kinetics in the chamber.
The model equations can be treated analytically in some
circumstances and complicated multi-dimensional models are solved
numerically with a software-package (UG unstructed grids, see [1]).
Because of multi-scaling and multi-physical behavior of the models,
we discuss adapted schemes to solve more accurate in the different
domains and scales. The results are discussed with physical
experiments to give a valid model for the assumed growth of thin
layers.
Abstract: In the normal operation conditions of a pico satellite,
conventional Unscented Kalman Filter (UKF) gives sufficiently good
estimation results. However, if the measurements are not reliable
because of any kind of malfunction in the estimation system, UKF
gives inaccurate results and diverges by time. This study, introduces
Robust Unscented Kalman Filter (RUKF) algorithms with the filter
gain correction for the case of measurement malfunctions. By the use
of defined variables named as measurement noise scale factor, the
faulty measurements are taken into the consideration with a small
weight and the estimations are corrected without affecting the
characteristic of the accurate ones. Two different RUKF algorithms,
one with single scale factor and one with multiple scale factors, are
proposed and applied for the attitude estimation process of a pico
satellite. The results of these algorithms are compared for different
types of measurement faults in different estimation scenarios and
recommendations about their applications are given.
Abstract: In this paper we analyze the application of a formal proof system to the discrete logarithm problem used in publickey cryptography. That means, we explore a computer verification of the ElGamal encryption scheme with the formal proof system Isabelle/HOL. More precisely, the functional correctness of this algorithm is formally verified with computer support. Besides, we present a formalization of the DSA signature scheme in the Isabelle/HOL system. We show that this scheme is correct what is a necessary condition for the usefulness of any cryptographic signature scheme.
Abstract: Today’s technology is heavily dependent on web applications. Web applications are being accepted by users at a very rapid pace. These have made our work efficient. These include webmail, online retail sale, online gaming, wikis, departure and arrival of trains and flights and list is very long. These are developed in different languages like PHP, Python, C#, ASP.NET and many more by using scripts such as HTML and JavaScript. Attackers develop tools and techniques to exploit web applications and legitimate websites. This has led to rise of web application security; which can be broadly classified into Declarative Security and Program Security. The most common attacks on the applications are by SQL Injection and XSS which give access to unauthorized users who totally damage or destroy the system. This paper presents a detailed literature description and analysis on Web Application Security, examples of attacks and steps to mitigate the vulnerabilities.
Abstract: Self-organizing map (SOM) is a well known data
reduction technique used in data mining. It can reveal structure in
data sets through data visualization that is otherwise hard to detect
from raw data alone. However, interpretation through visual
inspection is prone to errors and can be very tedious. There are
several techniques for the automatic detection of clusters of code
vectors found by SOM, but they generally do not take into account
the distribution of code vectors; this may lead to unsatisfactory
clustering and poor definition of cluster boundaries, particularly
where the density of data points is low. In this paper, we propose the
use of an adaptive heuristic particle swarm optimization (PSO)
algorithm for finding cluster boundaries directly from the code
vectors obtained from SOM. The application of our method to
several standard data sets demonstrates its feasibility. PSO algorithm
utilizes a so-called U-matrix of SOM to determine cluster boundaries;
the results of this novel automatic method compare very favorably to
boundary detection through traditional algorithms namely k-means
and hierarchical based approach which are normally used to interpret
the output of SOM.
Abstract: Medical images require special safety and confidentiality because critical judgment is done on the information provided by medical images. Transmission of medical image via internet or mobile phones demands strong security and copyright protection in telemedicine applications. Here, highly secured and robust watermarking technique is proposed for transmission of image data via internet and mobile phones. The Region of Interest (ROI) and Non Region of Interest (RONI) of medical image are separated. Only RONI is used for watermark embedding. This technique results in exact recovery of watermark with standard medical database images of size 512x512, giving 'correlation factor' equals to 1. The correlation factor for different attacks like noise addition, filtering, rotation and compression ranges from 0.90 to 0.95. The PSNR with weighting factor 0.02 is up to 48.53 dBs. The presented scheme is non blind and embeds hospital logo of 64x64 size.
Abstract: Nowadays, the demand for high product quality
focuses extensive attention to the quality of machined surface. The
(CNC) milling machine facilities provides a wide variety of
parameters set-up, making the machining process on the glass
excellent in manufacturing complicated special products compared to
other machining processes. However, the application of grinding
process on the CNC milling machine could be an ideal solution to
improve the product quality, but adopting the right machining
parameters is required. In glass milling operation, several machining
parameters are considered to be significant in affecting surface
roughness. These parameters include the lubrication pressure, spindle
speed, feed rate and depth of cut. In this research work, a fuzzy logic
model is offered to predict the surface roughness of a machined
surface in glass milling operation using CBN grinding tool. Four
membership functions are allocated to be connected with each input
of the model. The predicted results achieved via fuzzy logic model
are compared to the experimental result. The result demonstrated
settlement between the fuzzy model and experimental results with the
93.103% accuracy.