Abstract: In recent years, non-invasive Focused Ultrasound (FU) has been utilized for generating bubbles (cavities) to ablate target tissue by mechanical fractionation. Intensities >10 kW/cm2 are required to generate the inertial cavities. The generation, rapid growth, and collapse of these inertial cavities cause tissue fractionation and the process is called Histotripsy. The ability to fractionate tissue from outside the body has many clinical applications including the destruction of the tumor mass. The process of tissue fractionation leaves a void at the treated site, where all the affected tissue is liquefied to particles at sub-micron size. The liquefied tissue will eventually be absorbed by the body. Histotripsy is a promising non-invasive treatment modality. This paper presents a technique for generating inertial cavities at lower intensities (< 1 kW/cm2). The technique (patent pending) is based on amplitude modulation (AM), whereby a low frequency signal modulates the amplitude of a higher frequency FU wave. Cavitation threshold is lower at low frequencies; the intensity required to generate cavitation in water at 10 kHz is two orders of magnitude lower than the intensity at 1 MHz. The Amplitude Modulation technique can operate in both continuous wave (CW) and pulse wave (PW) modes, and the percentage modulation (modulation index) can be varied from 0 % (thermal effect) to 100 % (cavitation effect), thus allowing a range of ablating effects from Hyperthermia to Histotripsy. Furthermore, changing the frequency of the modulating signal allows controlling the size of the generated cavities. Results from in vitro work demonstrate the efficacy of the new technique in fractionating soft tissue and solid calcium carbonate (Chalk) material. The technique, when combined with MR or Ultrasound imaging, will present a precise treatment modality for ablating diseased tissue without affecting the surrounding healthy tissue.
Abstract: Magnetic Resonance Imaging (MRI) is one of the
most important medical imaging modality. Subjective assessment of
the image quality is regarded as the gold standard to evaluate MR
images. In this study, a database of 210 MR images which contains
ten reference images and 200 distorted images is presented. The
reference images were distorted with four types of distortions: Rician
Noise, Gaussian White Noise, Gaussian Blur and DCT compression.
The 210 images were assessed by ten subjects. The subjective scores
were presented in Difference Mean Opinion Score (DMOS). The
DMOS values were compared with four FR-IQA metrics. We have
used Pearson Linear Coefficient (PLCC) and Spearman Rank Order
Correlation Coefficient (SROCC) to validate the DMOS values. The
high correlation values of PLCC and SROCC shows that the DMOS
values are close to the objective FR-IQA metrics.
Abstract: In this paper, we present a new segmentation approach
for focal liver lesions in contrast enhanced ultrasound imaging. This
approach, based on a two-cluster Fuzzy C-Means methodology,
considers type-II fuzzy sets to handle uncertainty due to the image
modality (presence of speckle noise, low contrast, etc.), and to
calculate the optimum inter-cluster threshold. Fine boundaries are
detected by a local recursive merging of ambiguous pixels. The
method has been tested on a representative database. Compared to
both Otsu and type-I Fuzzy C-Means techniques, the proposed
method significantly reduces the segmentation errors.
Abstract: Photoacoustic imaging (PAI) is a non-invasive and
non-ionizing imaging modality that combines the absorption contrast
of light with ultrasound resolution. Laser is used to deposit optical
energy into a target (i.e., optical fluence). Consequently, the target
temperature rises, and then thermal expansion occurs that leads to
generating a PA signal. In general, most image reconstruction
algorithms for PAI assume uniform fluence within an imaging object.
However, it is known that optical fluence distribution within the
object is non-uniform. This could affect the reconstruction of PA
images. In this study, we have investigated the influence of optical
fluence distribution on PA back-propagation imaging using finite
element method. The uniform fluence was simulated as a triangular
waveform within the object of interest. The non-uniform fluence
distribution was estimated by solving light propagation within a
tissue model via Monte Carlo method. The results show that the PA
signal in the case of non-uniform fluence is wider than the uniform
case by 23%. The frequency spectrum of the PA signal due to the
non-uniform fluence has missed some high frequency components in
comparison to the uniform case. Consequently, the reconstructed
image with the non-uniform fluence exhibits a strong smoothing
effect.
Abstract: The process in which the complementary information from multiple images is integrated to provide composite image that contains more information than the original input images is called image fusion. Medical image fusion provides useful information from multimodality medical images that provides additional information to the doctor for diagnosis of diseases in a better way. This paper represents the wavelet based medical image fusion algorithm on different multimodality medical images. In order to fuse the medical images, images are decomposed using Redundant Wavelet Transform (RWT). The high frequency coefficients are convolved with morphological operator followed by the maximum-selection (MS) rule. The low frequency coefficients are processed by MS rule. The reconstructed image is obtained by inverse RWT. The quantitative measures which includes Mean, Standard Deviation, Average Gradient, Spatial frequency, Edge based Similarity Measures are considered for evaluating the fused images. The performance of this proposed method is compared with Pixel averaging, PCA, and DWT fusion methods. When compared with conventional methods, the proposed framework provides better performance for analysis of multimodality medical images.
Abstract: It was expected to benefit patient with hemiparesis after stroke by extensive arm rehabilitation, to partially regain forearm and hand function. This paper propose a robotic rehabilitation arm in assisting the hemiparetic patient to learn new ways of using and moving their weak arms. In this study, the robotic arm was driven by a somatosensory stimulated brain computer interface (BCI), which is a new modality BCI. The use of somatosensory stimulation is not only an input for BCI, but also a electrical stimulation for treatment of hemiparesis to strengthen the arm and improve its range of motion. A trial of this robotic rehabilitation arm was performed in a stroke patient with pure motor hemiparesis. The initial trial showed a promising result from the patient with great motivation and function improvement. It suggests that robotic rehabilitation arm driven by somatosensory BCI can enhance the rehabilitation performance and progress for hemiparetic patients after stroke.
Abstract: The multimodal biometric identification is the combination of several biometric systems; the challenge of this combination is to reduce some limitations of systems based on a single modality while significantly improving performance. In this paper, we propose a new approach to the construction and the protection of a multimodal biometric database dedicated to an identification system. We use a topological watermarking to hide the relation between face image and the registered descriptors extracted from other modalities of the same person for more secure user identification.
Abstract: Multimodal biometric systems integrate the data presented by multiple biometric sources, hence offering a better performance than the systems based on a single biometric modality. Although the coupling of biometric systems can be done at different levels, the fusion at the scores level is the most common since it has been proven effective than the rest of the fusion levels. However, the scores from different modalities are generally heterogeneous. A step of normalizing the scores is needed to transform these scores into a common domain before combining them. In this paper, we study the performance of several normalization techniques with various fusion methods in a context relating to the merger of three unimodal systems based on the face, the palmprint and the fingerprint. We also propose a new adaptive normalization method that takes into account the distribution of client scores and impostor scores. Experiments conducted on a database of 100 people show that the performances of a multimodal system depend on the choice of the normalization method and the fusion technique. The proposed normalization method has given the best results.
Abstract: The importance of logistics has changed enormously in the last few decades. While logistics was formerly one of the core functions of most companies, logistics or at least parts of their functions are nowadays outsourced to external logistic service providers in terms of contracts. As a result of this shift new business models like the fourth party logistics provider emerged, which designs, plans and monitors the resulting logistics networks. This new business model and topics such as Synchromodality or Big Data impose new requirements on the underlying IT, which cannot be met with conventional concepts and approaches.
In this paper, the challenges of logistics network monitoring are outlined by using a scenario. The most common layers in a logical multilayered architecture for an information system are used to point out the arising challenges for IT. In addition, first appropriate solution approaches are introduced.
Abstract: Does a communication modality matter in delivering e-learning information? With the recent growth of broadcasting systems, media technologies and e-learning contents, various systems with different communication modalities have been introduced. In accordance with these trends, this study examines the effects of the information delivery modality on psychology of students. Findings from an experiment indicated that the delivering information which includes a video modality elicited higher degrees of credibility, quality, representativeness of content, and perceived suitability for delivering information than those of auditory information. However, there is no difference between content liking and attitude. The Implications of the findings and the limitations are discussed.
Abstract: A registration framework for image-guided robotic
surgery is proposed for three emergency neurosurgical procedures,
namely Intracranial Pressure (ICP) Monitoring, External Ventricular
Drainage (EVD) and evacuation of a Chronic Subdural Haematoma
(CSDH). The registration paradigm uses CT and white light as
modalities. This paper presents two simulation studies for a
preliminary evaluation of the registration protocol: (1) The loci of the
Target Registration Error (TRE) in the patient-s axial, coronal and
sagittal views were simulated based on a Fiducial Localisation Error
(FLE) of 5 mm and (2) Simulation of the actual framework using
projected views from a surface rendered CT model to represent white
light images of the patient. Craniofacial features were employed as
the registration basis to map the CT space onto the simulated
intraoperative space. Photogrammetry experiments on an artificial
skull were also performed to benchmark the results obtained from the
second simulation. The results of both simulations show that the
proposed protocol can provide a 5mm accuracy for these
neurosurgical procedures.
Abstract: The purpose of this study was to investigate the effects of computer–based instructional designs, namely modality and redundancy principles on the attitude and learning of music theory among primary pupils of different Music Intelligence levels. The lesson of music theory was developed in three different modes, audio and image (AI), text with image (TI) and audio with image and text (AIT). The independent variables were the three modes of courseware. The moderator variable was music intelligence. The dependent variables were the post test score. ANOVA was used to determine the significant differences of the pretest scores among the three groups. Analyses of covariance (ANCOVA) and Post hoc were carried out to examine the main effects as well as the interaction effects of the independent variables on the dependent variables. High music intelligence pupils performed significantly better than low music intelligence pupils in all the three treatment modes. The AI mode was found to help pupils with low music intelligence significantly more than the TI and AIT modes.
Abstract: The stereophotogrammetry modality is gaining more widespread use in the clinical setting. Registration and visualization of this data, in conjunction with conventional 3D volumetric image modalities, provides virtual human data with textured soft tissue and internal anatomical and structural information. In this investigation computed tomography (CT) and stereophotogrammetry data is acquired from 4 anatomical phantoms and registered using the trimmed iterative closest point (TrICP) algorithm. This paper fully addresses the issue of imaging artifacts around the stereophotogrammetry surface edge using the registered CT data as a reference. Several iterative algorithms are implemented to automatically identify and remove stereophotogrammetry surface edge outliers, improving the overall visualization of the combined stereophotogrammetry and CT data. This paper shows that outliers at the surface edge of stereophotogrammetry data can be successfully removed automatically.
Abstract: Image compression is one of the most important
applications Digital Image Processing. Advanced medical imaging
requires storage of large quantities of digitized clinical data. Due to
the constrained bandwidth and storage capacity, however, a medical
image must be compressed before transmission and storage. There
are two types of compression methods, lossless and lossy. In Lossless
compression method the original image is retrieved without any
distortion. In lossy compression method, the reconstructed images
contain some distortion. Direct Cosine Transform (DCT) and Fractal
Image Compression (FIC) are types of lossy compression methods.
This work shows that lossy compression methods can be chosen for
medical image compression without significant degradation of the
image quality. In this work DCT and Fractal Compression using
Partitioned Iterated Function Systems (PIFS) are applied on different
modalities of images like CT Scan, Ultrasound, Angiogram, X-ray
and mammogram. Approximately 20 images are considered in each
modality and the average values of compression ratio and Peak
Signal to Noise Ratio (PSNR) are computed and studied. The quality
of the reconstructed image is arrived by the PSNR values. Based on
the results it can be concluded that the DCT has higher PSNR values
and FIC has higher compression ratio. Hence in medical image
compression, DCT can be used wherever picture quality is preferred
and FIC is used wherever compression of images for storage and
transmission is the priority, without loosing picture quality
diagnostically.
Abstract: An accurate optimal design of laminated composite
structures may present considerable difficulties due to the complexity
and multi-modality of the functional design space. The Big Bang
– Big Crunch (BB-BC) optimization method is a relatively new
technique and has already proved to be a valuable tool for structural
optimization. In the present study the exceptional efficiency of the
method is demonstrated by an example of the lay-up optimization
of multilayered anisotropic cylinders based on a three-dimensional
elasticity solution. It is shown that, due to its simplicity and speed,
the BB-BC is much more efficient for this class of problems when
compared to the genetic algorithms.
Abstract: In this paper we propose a novel approach for ascertaining human identity based on fusion of profile face and gait biometric cues The identification approach based on feature learning in PCA-LDA subspace, and classification using multivariate Bayesian classifiers allows significant improvement in recognition accuracy for low resolution surveillance video scenarios. The experimental evaluation of the proposed identification scheme on a publicly available database [2] showed that the fusion of face and gait cues in joint PCA-LDA space turns out to be a powerful method for capturing the inherent multimodality in walking gait patterns, and at the same time discriminating the person identity..
Abstract: Biologically human brain processes information in both unimodal and multimodal approaches. In fact, information is progressively abstracted and seamlessly fused. Subsequently, the fusion of multimodal inputs allows a holistic understanding of a problem. The proliferation of technology has exponentially produced various sources of data, which could be likened to being the state of multimodality in human brain. Therefore, this is an inspiration to develop a methodology for exploring multimodal data and further identifying multi-view patterns. Specifically, we propose a brain inspired conceptual model that allows exploration and identification of patterns at different levels of granularity, different types of hierarchies and different types of modalities. A structurally adaptive neural network is deployed to implement the proposed model. Furthermore, the acquisition of multi-view patterns with the proposed model is demonstrated and discussed with some experimental results.
Abstract: As the use of registration packages spreads, the number of the aligned image pairs in image databases (either by manual or automatic methods) increases dramatically. These image pairs can serve as a set of training data. Correspondingly, the images that are to be registered serve as testing data. In this paper, a novel medical image registration method is proposed which is based on the a priori knowledge of the expected joint intensity distribution estimated from pre-aligned training images. The goal of the registration is to find the optimal transformation such that the distance between the observed joint intensity distribution obtained from the testing image pair and the expected joint intensity distribution obtained from the corresponding training image pair is minimized. The distance is measured using the divergence measure based on Tsallis entropy. Experimental results show that, compared with the widely-used Shannon mutual information as well as Tsallis mutual information, the proposed method is computationally more efficient without sacrificing registration accuracy.
Abstract: The purpose of this study is to investigate the effects
of modality principles in instructional software among first grade
pupils- achievements in the learning of Arabic Language. Two modes
of instructional software were systematically designed and
developed, audio with images (AI), and text with images (TI). The
quasi-experimental design was used in the study. The sample
consisted of 123 male and female pupils from IRBED Education
Directorate, Jordan. The pupils were randomly assigned to any one of
the two modes. The independent variable comprised the two modes
of the instructional software, the students- achievement levels in the
Arabic Language class and gender. The dependent variable was the
achievements of the pupils in the Arabic Language test. The
theoretical framework of this study was based on Mayer-s Cognitive
Theory of Multimedia Learning. Four hypotheses were postulated
and tested. Analyses of Variance (ANOVA) showed that pupils using
the (AI) mode performed significantly better than those using (TI)
mode. This study concluded that the audio with images mode was an
important aid to learning as compared to text with images mode.
Abstract: Detection of human emotions has many potential applications. One of application is to quantify attentiveness audience in order evaluate acoustic quality in concern hall. The subjective audio preference that based on from audience is used. To obtain fairness evaluation of acoustic quality, the research proposed system for multimodal emotion detection; one modality based on brain signals that measured using electroencephalogram (EEG) and the second modality is sequences of facial images. In the experiment, an audio signal was customized which consist of normal and disorder sounds. Furthermore, an audio signal was played in order to stimulate positive/negative emotion feedback of volunteers. EEG signal from temporal lobes, i.e. T3 and T4 was used to measured brain response and sequence of facial image was used to monitoring facial expression during volunteer hearing audio signal. On EEG signal, feature was extracted from change information in brain wave, particularly in alpha and beta wave. Feature of facial expression was extracted based on analysis of motion images. We implement an advance optical flow method to detect the most active facial muscle form normal to other emotion expression that represented in vector flow maps. The reduce problem on detection of emotion state, vector flow maps are transformed into compass mapping that represents major directions and velocities of facial movement. The results showed that the power of beta wave is increasing when disorder sound stimulation was given, however for each volunteer was giving different emotion feedback. Based on features derived from facial face images, an optical flow compass mapping was promising to use as additional information to make decision about emotion feedback.