Abstract: The venture capital becomes more and more advanced
and effective source of the innovation project financing, connected
with a high-risk level. In the developed countries, it plays a key role
in transforming innovation projects into successful businesses and
creating the prosperity of the modern economy. In Russia, there are
many necessary preconditions for creation of the effective venture
investment system: the network of the public institutes for innovation
financing operates; there is a significant number of the small and
medium-sized enterprises, capable to sell production with good
market potential. However, the current system does not confirm the
necessary level of efficiency in practice that can be substantially
explained by the absence of the accurate plan of action to form the
national venture model and by the lack of experience of successful
venture deals with profitable exits in Russian economy. This paper
studies the influence of various factors on the venture industry
development by the example of the IT-sector in Russia. The choice of
the sector is based on the fact, that this segment is the main driver of
the venture capital market growth in Russia, and the necessary set of
data exists. The size of investment of the second round is used as the
dependent variable. To analyse the influence of the previous round,
such determinant as the volume of the previous (first) round
investments is used. There is also used a dummy variable in
regression to examine that the participation of an investor with high
reputation and experience in the previous round can influence the size
of the next investment round. The regression analysis of short-term
interrelations between studied variables reveals prevailing influence
of the volume of the first round investments on the venture
investments volume of the second round. The most important
determinant of the value of the second-round investment is the value
of first–round investment, so it means that the most competitive on
the Russian market are the start-up teams that can attract more money
on the start, and the target market growth is not the factor of crucial
importance. This supports the point of view that VC in Russia is
driven by endogenous factors and not by exogenous ones that are
based on global market growth.
Abstract: In order to determine the impact of thermo priming on germination of soybean seeds, an experiment was conducted as a completely randomized design with three replications. The factors of studied included different time thermo priming (control, 5 and 10 minutes) through the placing seeds were exposed to oven. The results showed that the effect of thermo priming was significant on germination percentage, seedling dry weight and seedling vigour in P ≤ 0.05. Mean comparison showed that the highest germination percentage (77%), seedling dry weight (1.39 g) and seedling vigour (107.03) were achieved by 10 minutes thermo priming.
Abstract: Electrohydraulic servo system have been used in industry in a wide number of applications. Its dynamics are highly nonlinear and also have large extent of model uncertainties and external disturbances. In this paper, a robust back-stepping control (RBSC) scheme is proposed to overcome the problem of disturbances and system uncertainties effectively and to improve the tracking performance of EHS systems. In order to implement the proposed control scheme, the system uncertainties in EHS systems are considered as total leakage coefficient and effective oil volume. In addition, in order to obtain the virtual controls for stabilizing system, the update rule for the system uncertainty term is induced by the Lyapunov control function (LCF). To verify the performance and robustness of the proposed control system, computer simulation of the proposed control system using Matlab/Simulink Software is executed. From the computer simulation, it was found that the RBSC system produces the desired tracking performance and has robustness to the disturbances and system uncertainties of EHS systems.
Abstract: There is not much effective guideline on development of design parameters selection on spring back for advanced high strength steel sheet metal in U-channel process during cold forming process. This paper presents the development of predictive model for spring back in U-channel process on advanced high strength steel sheet employing Response Surface Methodology (RSM). The experimental was performed on dual phase steel sheet, DP590 in Uchannel forming process while design of experiment (DoE) approach was used to investigates the effects of four factors namely blank holder force (BHF), clearance (C) and punch travel (Tp) and rolling direction (R) were used as input parameters using two level values by applying Full Factorial design (24 ). From a statistical analysis of variant (ANOVA), result showed that blank holder force (BHF), clearance (C) and punch travel (Tp) displayed significant effect on spring back of flange angle (β2 ) and wall opening angle (β1 ), while rolling direction (R) factor is insignificant. The significant parameters are optimized in order to reduce the spring back behavior using Central Composite Design (CCD) in RSM and the optimum parameters were determined. A regression model for spring back was developed. The effect of individual parameters and their response was also evaluated. The results obtained from optimum model are in agreement with the experimental values.
Abstract: An experiment was conducted to elucidate the effects of turmeric powder supplementation on egg production performance of old laying hens (80 weeks of age). There were 40 hens of Hysex Brown strain used in the study. They were caged individually, and randomly divided into 4 treatment groups of diet containing 0 (control), 1, 2 and 4 % oven dried turmeric powder for 3 periods of 4 weeks; Egg production (% hen day) and feed intake of the 4 treatment groups at the commencement of the experiment were not significantly different. In addition to egg production performance (% and egg weight), feed and water intakes were measured daily, and cholesterol content of the whole egg was determined. The results indicated that feed intakes of the hen were significantly lowered when 4% turmeric powder supplemented, while there were no significant changes in water intakes. Egg production were significantly increased and maintained at a higher level by turmeric powder supplementation up to 4% compared with the control, while the weight of eggs were not significantly affected. The research markedly demonstrated that supplementation of turmeric powder up to 4% could improve and maintain egg production performance of the old laying hen at a higher level with a lower cholesterol content.
Abstract: This study addresses a concept of the Sustainable Building Environmental Model (SBEM) developed to optimize energy consumption in air conditioning and ventilation (ACV) systems without any deterioration of indoor environmental quality (IEQ). The SBEM incorporates two main components: an adaptive comfort temperature control module (ACT) and a new carbon dioxide demand control module (nDCV). These two modules take an innovative approach to maintain satisfaction of the Indoor Environmental Quality (IEQ) with optimum energy consumption; they provide a rational basis of effective control. A total of 2133 sets of measurement data of indoor air temperature (Ta), relative humidity (Rh) and carbon dioxide concentration (CO2) were conducted in some Hong Kong offices to investigate the potential of integrating the SBEM. A simulation was used to evaluate the dynamic performance of the energy and air conditioning system with the integration of the SBEM in an air-conditioned building. It allows us make a clear picture of the control strategies and performed any pre-tuned of controllers before utilized in real systems. With the integration of SBEM, it was able to save up to 12.3% in simulation of overall electricity consumption, and maintain the average carbon dioxide concentration within 1000ppm and occupant dissatisfaction in 20%.
Abstract: Doxorubicin (DOX) is an anthracycline drug used to treat many cancer diseases. Similarly to other cytostatic drugs, DOX has serious side effects; the biggest obstacle is the cardiotoxicity. With the aim of lowering the negative side effects and to target the DOX into the tumor tissue, the different nanoparticles (NPs) are studied. The aim of this work was to synthetized different NPs and conjugated them with DOX and determine the binding capacity of the NPs. For this experiment, carbon nanotubes (CNTs), graphene oxide (GO), fullerene (FUL) and liposomes (LIP) were used. The highest binding capacity was observed in GO (85%). Subsequently the toxicity of NPs and NPs-DOX conjugates was analyzed in in vivo system (chicken embryos). Some NPs (GO) can increase the toxicity of DOX, whereas other NPs (LIP, CNTs) decrease DOX toxicity.
Abstract: This study will examine how the therapeutic factors
(therapeutic catharsis-seeking and game-efficacy of the game player)
and self-construal factors (independent and interdependent
self-construal of the game player) as well as social capital factors
(bonding and bridging social capital of the game player) affect
aggression in the game. Results show that both therapeutic
catharsis-seeking and game self-efficacy are particularly important to
the players since they cause the game players’ aggressive tendencies to
be greatly diminished. Independent self-construal reduces the level of
the players’ aggression. Interestingly enough, the bonding social
capital enhances the level of the players’ aggression, while individuals
with bridging social capital did not show any significant effects. The
results and implications will be discussed herein.
Abstract: Distributed applications deployed on LEO satellites
and ground stations require substantial communication between
different members in a constellation to overcome the earth
coverage barriers imposed by GEOs. Applications running on LEO
constellations suffer the earth line-of-sight blockage effect. They
need adequate lab testing before launching to space. We propose
a scalable cloud-based network simulation framework to simulate
problems created by the earth line-of-sight blockage. The framework
utilized cloud IaaS virtual machines to simulate LEO satellites
and ground stations distributed software. A factorial ANOVA
statistical analysis is conducted to measure simulator overhead on
overall communication performance. The results showed a very low
simulator communication overhead. Consequently, the simulation
framework is proposed as a candidate for testing LEO constellations
with distributed software in the lab before space launch.
Abstract: Complex lifting entry was selected for precise landing
performance during the Mars Science Laboratory entry. This study
aims to develop the three-dimensional numerical method for precise
computation and the surface panel method for rapid engineering
prediction. Detailed flow field analysis for Mars exploration mission
was performed by carrying on a series of fully three-dimensional
Navier-Stokes computations. The static aerodynamic performance was
then discussed, including the surface pressure, lift and drag coefficient,
lift-to-drag ratio with the numerical and engineering method.
Computation results shown that the shock layer is thin because of
lower effective specific heat ratio, and that calculated results from both
methods agree well with each other, and is consistent with the
reference data. Aerodynamic performance analysis shows that CG
location determines trim characteristics and pitch stability, and certain
radially and axially shift of the CG location can alter the capsule lifting
entry performance, which is of vital significance for the aerodynamic
configuration design and inner instrument layout of the Mars entry
capsule.
Abstract: Knowledge of bone mechanical properties is important
for bone substitutes design and fabrication, and more efficient
prostheses development. The aim of this study is to characterize the
viscoelastic behavior of bone specimens, through stress relaxation
and fatigue tests performed to trabecular bone samples from bovine
femoral heads. Relaxation tests consisted on preloading the samples
at five different magnitudes and evaluate them for 1020 seconds,
adjusting the results to a KWW mathematical model. Fatigue tests
consisted of 700 load cycles and analyze their status at the end of the
tests. As a conclusion we have that between relaxation stress and
each preload there is linear relation and for samples with initial
Young´s modulus greater than 1.5 GPa showed no effects due fatigue
test loading cycles.
Abstract: In this paper, we are interested in the problem of
finding similar images in a large database. For this purpose we
propose a new algorithm based on a combination of the 2-D
histogram intersection in the HSV space and statistical moments. The
proposed histogram is based on a 3x3 window and not only on the
intensity of the pixel. This approach overcome the drawback of the
conventional 1-D histogram which is ignoring the spatial distribution
of pixels in the image, while the statistical moments are used to
escape the effects of the discretisation of the color space which is
intrinsic to the use of histograms. We compare the performance of
our new algorithm to various methods of the state of the art and we
show that it has several advantages. It is fast, consumes little memory
and requires no learning. To validate our results, we apply this
algorithm to search for similar images in different image databases.
Abstract: Biomass briquette gasification is regarded as a
promising route for efficient briquette use in energy generation, fuels
and other useful chemicals. However, previous research has been
focused on briquette gasification in fixed bed gasifiers such as
updraft and downdraft gasifiers. Fluidised bed gasifier has the
potential to be effectively sized to medium or large scale. This study
investigated the use of fuel briquettes produced from blends of rice
husks and corn cobs biomass, in a bubbling fluidised bed gasifier.
The study adopted a combination of numerical equations and Aspen
Plus simulation software, to predict the product gas (syngas)
composition base on briquette density and biomass composition
(blend ratio of rice husks to corn cobs). The Aspen Plus model was
based on an experimentally validated model from the literature. The
results based on a briquette size 32 mm diameter and relaxed density
range of 500 to 650kg/m3, indicated that fluidisation air required in
the gasifier increased with increase in briquette density, and the
fluidisation air showed to be the controlling factor compared with the
actual air required for gasification of the biomass briquettes. The
mass flowrate of CO2 in the predicted syngas composition increased
with an increase in air flow, in the gasifier, while CO decreased and
H2 was almost constant. The ratio of H2 to CO for various blends of
rice husks and corn cobs did not significantly change at the designed
process air, but a significant difference of 1.0 was observed between
10/90 and 90/10 % blend of rice husks and corn cobs.
Abstract: More than 3000 plants of notable phyto-therapeutic
value grow in South Africa; these include Cissampelos capensis,
commonly known in Afrikaans as dawidjie or dawidjiewortel. C.
capensis is the most significant and popular medicinal plant used by
the Khoisan as well as other rural groups in the Western region of
South Africa. Its rhizomes are traditionally used to treat male fertility
problems. Yet, no studies have investigated the effects of this plant or
its extracts on human spermatozoa. Therefore, this study aimed at
investigating the effects of C. capensis rhizome extract (CRE)
fractions on ejaculated human spermatozoa in vitro. Spermatozoa
from a total of 77 semen samples were washed with human tubular
fluid medium supplemented with bovine serum albumin (HTF-BSA)
and incubated for 2 hours with 20 μg/ml progesterone (P4) followed
by incubation with different concentrations (0, 0.05, 0.5, 5, 50, 200
μg/ml) of fractionated CRE (F1=0% MeOH, F2=30% MeOH,
F3=60% MeOH and F4=100% MeOH) for 1.5 hours at 37°C. A
sample without addition of CRE fractions served as control. Samples
were analyzed for sperm motility, reactive oxygen species (ROS),
DNA-fragmentation, acrosome reaction and capacitation. Results
showed that F1 resulted in significantly higher values for ROS,
capacitation and hyper-activation compared to F2, F3, and F4 with
P4-stimulated samples generally having higher values. No significant
effect was found for the other parameters. In conclusion, alkaloids
present in F1 of CRE appear to have triggered sperm intrinsic ROS
production leading to sperm capacitation and acrosome reaction
induced by P4.
Abstract: Copper (I) oxide microparticles with the morphology
of cubic and hollow sphere were synthesized with the assistance of
surfactant as the shape controller. Both particles were then subjected
to study the catalytic activity and observed the results of shape effects
of catalysts on rate of catalytic reaction. The decolorizing reaction of
crystal violet and sodium hydroxide was chosen and measured the
decreasing of reactant with respect to times using spectrophotometer.
The result revealed that morphology of crystal had no effect on the
catalytic activity for crystal violet reaction but contributed to total
surface area predominantly.
Abstract: In this study, the pedestrian simulation VISWALK
integration and application platform ant algorithms written program
made to construct a renovation engineering schedule planning mode.
The use of simulation analysis platform construction site when the user
running the simulation, after calculating the user walks in the case of
construction delays, the ant algorithm to find out the minimum delay
time schedule plan, and add volume and unit area deactivated loss of
business computing, and finally to the owners and users of two
different positions cut considerations pick out the best schedule
planning. To assess and validate its effectiveness, this study
constructed the model imported floor of a shopping mall floor
renovation engineering cases. Verify that the case can be found from
the mode of the proposed project schedule planning program can
effectively reduce the delay time and the user's walking mall loss of
business, the impact of the operation on the renovation engineering
facilities in the building to a minimum.
Abstract: Metal thin-walled members have been widely used in
building industry. Usually they are utilized as purlins, girts or ceiling
beams. Due to slenderness of thin-walled cross-sections these
structural members are prone to stability problems (e.g. flexural
buckling, lateral torsional buckling). If buckling is not
constructionally prevented their resistance is limited by buckling
strength. In practice planar members of roof or wall cladding can be
attached to thin-walled members. These elements reduce
displacement of thin-walled members and therefore increase their
buckling strength. If this effect is taken into static assessment more
economical sections of thin-walled members might be utilized and
certain savings of material might be achieved. This paper focuses on
problem of determination of critical load of steel thin-walled beams
with lateral continuous restraint which is crucial for lateral torsional
buckling assessment.
Abstract: The Economic Lot Scheduling Problem (ELSP) is a
valuable mathematical model that can support decision-makers to
make scheduling decisions. The basic period approach is effective for
solving the ELSP. The assumption for applying the basic period
approach is that a product must use its maximum production rate to be
produced. However, a product can lower its production rate to reduce
the average total cost when a facility has extra idle time. The past
researches discussed how a product adjusts its production rate under
the common cycle approach. To the best of our knowledge, no studies
have addressed how a product lowers its production rate under the
basic period approach. This research is the first paper to discuss this
topic. The research develops a simple fixed rate approach that adjusts
the production rate of a product under the basic period approach to
solve the ELSP. Our numerical example shows our approach can find a
better solution than the traditional basic period approach. Our
mathematical model that applies the fixed rate approach under the
basic period approach can serve as a reference for other related
researches.
Abstract: Nowadays, the main goal for modern horticultural
production is an increase the quality. In recent years, the use of
organic fertilizers or biostimulants that can be applied in agriculture
to improve quali-quantitative crop yields has encountered increasing
interest. Biostimulants are gaining importance also for their possible
use in organic and sustainable agriculture, to avoid excessive
fertilizer applications. Consecutive experimental trials were carried
out in the Apulia region (southern Italy) on three herbaceous crops
(cauliflower, pepper, fennel) grown in pots under conventional and
organic fertilization systems without and with biostimulants. The aim
was to determine the effects of three biostimulants (Siapton®10L,
Micotech L, Lysodin Alga-Fert) on quali-quantitative yield
characteristics. At harvest, the quali-quantitative yield characteristics
of each crop were determined. All of the experimental data were
subjected to analysis of variance (ANOVA), and when significant
effects were detected, the means were compared using Tukey’s tests.
These data show large differences in these yield characteristics
between conventional and organic crops, particularly highlighting
higher yields for the conventional crops, while variable results were
generally observed when the biostimulants were applied. In this
context, there were no effects of the biostimulants on the quantitative
yield, whereas there were low positive effects on the qualitative
characteristics, as related to higher dry matter content of cauliflower,
and higher soluble solids content of pepper. Moreover, there were
evident positive effects of the biostimulants with fennel, due to the
lower nitrate content. These latter data are in line with most of the
published literature obtained for other herbaceous crops.
Abstract: Current research is targeting new molecular
mechanisms that underlie non-alcoholic fatty liver disease (NAFLD)
and associated metabolic disorders like non-alcoholic steatohepatitis
(NASH). Forty New Zealand White rabbits have been used and fed a
high protein (HP) and energy diet based on grains and containing
11.76 MJ/kg. Boron added to 3 experimental groups’ drinking waters
(30 mg boron/L) as boron compounds. Biochemical analysis
including boron levels, and nuclear magnetic resonance (NMR) based
metabolomics evaluation, and mRNA expression of peroxisome
proliferator-activated receptor (PPAR) family was performed. LDLcholesterol
concentrations alone were decreased in all the
experimental groups. Boron levels in serum and feces were increased.
Content of acetate was in about 2x higher for anhydrous borax group,
at least 3x higher for boric acid group. PPARα mRNA expression
was significantly decreased in boric acid group. Anhydrous borax
attenuated mRNA levels of PPARγ, which was further suppressed by
boric acid. Boron supplementation decreased the degenerative
alterations in hepatocytes. Except borax group other boron groups did
not have a pronounced change in tubular epithels of kidney. In
conclusion, high protein and energy diet leads hepatocytes’
degenerative changes which can be prevented by boron
supplementation. Boric acid seems to be more effective in this
situation.