Egg Production Performance of Old Laying Hen Fed Dietary Turmeric Powder
An experiment was conducted to elucidate the effects of turmeric powder supplementation on egg production performance of old laying hens (80 weeks of age). There were 40 hens of Hysex Brown strain used in the study. They were caged individually, and randomly divided into 4 treatment groups of diet containing 0 (control), 1, 2 and 4 % oven dried turmeric powder for 3 periods of 4 weeks; Egg production (% hen day) and feed intake of the 4 treatment groups at the commencement of the experiment were not significantly different. In addition to egg production performance (% and egg weight), feed and water intakes were measured daily, and cholesterol content of the whole egg was determined. The results indicated that feed intakes of the hen were significantly lowered when 4% turmeric powder supplemented, while there were no significant changes in water intakes. Egg production were significantly increased and maintained at a higher level by turmeric powder supplementation up to 4% compared with the control, while the weight of eggs were not significantly affected. The research markedly demonstrated that supplementation of turmeric powder up to 4% could improve and maintain egg production performance of the old laying hen at a higher level with a lower cholesterol content.
[1] Beevers C.S., and S. Huang. 2011. Pharmacological and clinical
properties of curcumin, Review. Botanics: Targets and Therapy, 1: 5-
18
[2] Chattopadhyay, I. K., U. Biswa, Bandyopadhyay and R. K.
Banerjeeil, 2004. Turmeric and Curcumin: Biological actions and
medicinal applications. Current Sci., 87 (1): 44-53
[3] Krup, V., L.H. Prakash, and A. Harini. 2013. Pharmacological
Activities of Turmeric (Curcuma longa Linn): A Review. J Homeop
Ayurv Med., 2 – 133: doi:10.4172/2167-1206.1000133.
[4] Kuroda, M., Y. Mimaki, and T. Nishiyama. 2005. Hypoglycemic
effects of turmeric (Curcuma longa L. rhizomes) on genetically
diabetic KKAy mice. Biol. Pharm. Bull., 28, 937-939.
[5] Li, S., Y. Wei, D. Guangrui, W. Ping, Y. Peiying and B. A. Aggarwal.
2011. Chemical Composition and Product Quality Control of
Turmeric (Curcuma longa L.). Pharmaceutical Crops, 2: 28-54
[6] Thaloor, D. 1999. Systemic administration of the NF-kappaB
inhibitor curcumin stimulates muscle regeneration after traumatic
injury. Am. J. Physiol., 277 (2pt 1): C320 – C329.
[7] Puwastien, P., T.E. Siong, J. Kantasubrata, G. Caven, R.R.
Felicionoand and K. Judprasong, 2011. Asean Manual of Food
Analysis. Regional centre of Asean Network of Food Data System.
Institute of Nutrition, Mahidol University Thailand, pp. 1-190.
[8] Wilkinson, L. 1996. Statistics, Systat for Windows. SPSS Inc., USA..
pp. 183-223
[9] Maha, B. 2013. Antidiabetic Potential of Turmeric with/without
Fermented Milk Enriched with Probiotics in Diabetic Rats. Am. J. of
Biomed and Life Sci., 1(1): 1-7
[10] Seo, K. L., M. S. Choi, U. J. Jung, H. J. Kim, J. Yeo, S. M. Jeon and
M. K. Lee, 2008. Effect of curcumin supplementation on blood
glucose, plasma insulin and glucose homeostasis related enzyme
activities in diabetic db/db mice. Mol. Nutr. Food Res., 52: 995-1004.
[11] Wickenberg, J., S. L. Ingemansson, J., and Hlebowicz. 2010. Effects
of Curcuma longa (turmeric) on postprandial plasma glucose and
insulin in healthy subjects. Nutrition J., 9: 43 (1- 5).
[12] Aggarwal, B. B., C. Sundaram, N. Malani and H. Ichikawa, 2007.
Curcumin: The Indian Solid Gold. Adv. Exp. Med. Biol., 595: 1-75
[13] Rivera-Espinoza, Y. and P. Muriel, 2009. Pharmacological actions of
curcumin in liver diseases or damage. Liver Int., 29: 1457-1466.
[14] Radwan, L., R.A. Hassan, E.M. Qota and H.M. Fayek. 2008. Effect of
Natural Antioxidant on Oxidative Stability of Eggs and Productive
and Reproductive Performance of Laying Hens. Int. J. Poult. Sci.,
7(2): 134-150.
[15] Reyes-Gordillo, K., J. Segovia, M. Shibayama, P. Vergara, M.G.
Moreno and P. Muriel, 2007. Curcumin protects against acute liver
damage in the rat by inhibiting NF-kappaB, proinflammatory
cytokines production and oxidative stress. Biochim. Biophys. Acta.,
1770: 989-996.
[16] Reyes-Gordillo, K., J. Segovia, M. Shibayama, V. Tsutsumi, P.
Vergara, M.G. Moreno and P. Muriel. 2008. Curcumin prevents and
reverses cirrhosis induced by bile duct obstruction or CCl4 in rats:
Role of TGF-beta modulation and oxidative stress. Role of TGF-beta
modulation and oxidative stress. Fundam. Clin. Pharmacol., 22: 417-
427.
[17] Burley, R. W., A. J. Evans and J. A. Pearson, 1993. Molecular aspects
of the synthesis and deposition of hens' egg yolk with special
reference to low density lipoprotein. Poult. Sci., 72: 850-855.
[18] Etches, R. J. 1996. Reproduction in Poultry. Singapore. CAB.
Internatiuonal, pp. 125-166
[19] Steven, L. 2004. Avian biochemistry and molecular biology.
Cmbridge University Press, UK, pp. 46-81.
[20] Saraswati, T. R., W. Manalu, R.E. Damiana and N. Kusumorini.
2013. Increased Egg Production of Japanese Quail (Cortunix
japonica) by Improving Liver Function Through Turmeric Powder
Supplementation. Int. J. Poultry Sci., 12 (10): 601-614.
[21] Chattopadhyay, I.K., U. Biswa, Bandyopadhyay and R. K. Banerjeeil,
2004. Turmeric and Curcumin: Biological action and medicinal
applications. Review article. Curr. Sci., 87: 44-53.
[22] Sreejayan, N. and M.N. Rao, 1996. Free radical scavenging activity of
curcuminoid. Drug Res., 46:169-171.
[23] Somchit, M.N., A. Zuraini, A. Bustamam, M.R. Sulaiman and R.
Nuratunlina, 2005. Protective activity of turmeric (Curcuma longa) in
paracetamol induced hepatotoxicity in rat. Int. J. Pharmacol., 1: 252-
256.
[24] Elkin, R. G., Z. Yan, Y. Zhong, S. S. Donkin, K. K. Buhma, J. A.
Story, J. J. Turek, R. E. Porter Jr, M. Anderson, R. Homan and R.S.
Newton, 1999. Select 3-hydroxy-3-methylglutarylcoenzym A
reductase inhibitors vary in their ability to reduce egg yolk cholesterol
levels in laying hens trough alteration of hepatic cholesterol
biosynthesis and plasma VLDL composition. J.Nutr., 129: 1010-1019.
[25] Babu, P.S., K. Srinivasan. 1997. Hypolipidemic action of curcumin,
the active principle of turmeric (Curcuma longa) in streptozotocin
induced diabetic rats. Mol. Cell Biochem., 166: 169–175.
[26] Kim, M. and Kim, Y. 2010.Hypocholesterolemic effects of curcumin
via up-regulation of cholesterol 7a-hydroxylase in rats fed a high
fatdiet. Nutr. Res.Pract., 4(3):191-195.
[27] Gylling, H. and T.A. Miettinen. 1995. The effect of cholesterol
absorption inhibition on low density lipoprotein cholesterol level.
Atherosclerosis, 117:305-308.
[28] Altmann, S.W., H.R. Davis Jr., L.J. Zhu, X. Yao, L.M. Hoos, G.
Tetzloff, S.P. Iyer, M. Maguire, A. Golovko and M.Zeng. 2004.
Niemann-Pick C1 Like 1protein is critical for intestinal cholesterol
absorption. Science, 303(5661): 1201-1204.
[29] Feng, D., Ohlsson, L. and D. Rui-Dong.2010.Curcumin inhibits
cholesterol uptake in Caco-2cells by down-regulation of NPC1L1
expression. Lipids in Health and Disease, 9: 40–45.
[30] Arafa, H.M. 2005.Curcumin attenuates diet-induced hypercholesterolemia
in rats. Med. Sci. Monit., 11: BR228– BR234
[31] Rao DS, Sekhara NC, Satyanarayana MN, Srinivasan M (1970).
Effect of curcumin on serum and liver cholesterol levels in the rat. J.
Nutr., 100: 1307–1315.
[32] Kuwabara, T., K.H. Han, N. Hashimoto, H. Yamauchi, K. Shimada,
M. Sekikawa and M. Fukushima. 2007. Tartary buckwheat sprout
powder lowers plasma cholesterol level in rats. J. Nutr. Sci. Vitaminol
(Tokyo), 53:501-7.
[33] Peschel D, Koerting R, Nass N (2007). Curcumin induces changes
expression of genes involved in cholesterol homeostasis. J. Nutr.
Biochem., 18: 113–119.
[34] Ramirez-Tortosa, M. C., M. D. Mesa, M. C. Aguilera, J. L. Quiles, L.
Baro and C. Ramirez-Tortosa.1999. Oral administration of a turmeric
extract inhibits LDL oxidation and has hypocholesterolemic effects in
rabbits with experimental atherosclerosis. Atherosclerosis, 147: 371–
378.
[35] Xu, J., Y. Fu and A. Chen. 2003. Activation of peroxisome
proliferator activated receptor-gamma contributes to the inhibitory
effects of curcumin on rat hepatic stellate cell growth. Am. J. Physiol.
Gastrointest, Liver Physiol., 285: G20–G30.
[36] Zheng, S. and A. Chen. 2006. Curcumin suppresses the expression of
extracellular matrix genes in activated hepatic stellate cells by
inhibiting gene expression of connective tissue growth factor. Am. J.
Physiol. Gastrointest, Liver Physiol., 290: G883–G893.
[37] Zhou, Y., S. Zheng, J. Lin, Q. J. Zhang and A. Chen. 2007. The
interruption of the PDGF and EGF signaling pathways by curcumin
stimulates gene expression of PPAR gamma in rat activated hepatic
stellate cell in vitro. Lab. Invest., 87: 488–498.
[38] Zheng, S., F. Yumei and A. Chen. 2007. De novo synthesis of
glutathione is a prerequisite for curcumin to inhibit hepatic stellate
cell (HSC) activation. Free Radic. Biol. Med., 43: 444–453.
[39] Park, E. J., C.H. Jeon, G. Ko, J. Kim and D. H. Sohn. 2000. Protective
effect of curcumin in rat liver injury induced by carbon tetrachloride.
J. Pharm.Pharmacol.,52: 437–440.
[40] Nanji, A. A., K. Jokelainen, G. L. Tipoe, A. Rahemtulla, P. Thomas
and Dannenberg, A. J. 2003. Curcumin prevents alcohol-induced liver
disease in rats by inhibiting the expression of NF-kappa B-dependent
genes. Am. J. Physiol. Gastrointest. Liver Physiol., 284: G321–G327.
[41] Fu, Y., S. Zheng, J. Lin, J. Ryerse, A. Chen. 2008. Curcumin protects
the rat liver from CCl4-caused injury and fibrogenesis by attenuating
oxidative stress and suppressing inflammation. Mol. Pharmacol.
73:399–409.
[42] Kang, Q. and Chen, A. 2009. Curcumin suppresses expression of lowdensity
lipoprotein (LDL) receptor, leading to the inhibition of LDLinduced
activation of hepatic stellate cells. Brit. J. Pharmac., 157:
1354–136.
[43] Saraswati, T. R., W. Manalu, D. R. Ekastuti and N. Kusumorini.
2013. The role of turmeric powder in lipid metabolism and its effect
on quality of the first quail’s egg. J. Indonesian Trop. Anim. Agric.
38: 123-130.
[1] Beevers C.S., and S. Huang. 2011. Pharmacological and clinical
properties of curcumin, Review. Botanics: Targets and Therapy, 1: 5-
18
[2] Chattopadhyay, I. K., U. Biswa, Bandyopadhyay and R. K.
Banerjeeil, 2004. Turmeric and Curcumin: Biological actions and
medicinal applications. Current Sci., 87 (1): 44-53
[3] Krup, V., L.H. Prakash, and A. Harini. 2013. Pharmacological
Activities of Turmeric (Curcuma longa Linn): A Review. J Homeop
Ayurv Med., 2 – 133: doi:10.4172/2167-1206.1000133.
[4] Kuroda, M., Y. Mimaki, and T. Nishiyama. 2005. Hypoglycemic
effects of turmeric (Curcuma longa L. rhizomes) on genetically
diabetic KKAy mice. Biol. Pharm. Bull., 28, 937-939.
[5] Li, S., Y. Wei, D. Guangrui, W. Ping, Y. Peiying and B. A. Aggarwal.
2011. Chemical Composition and Product Quality Control of
Turmeric (Curcuma longa L.). Pharmaceutical Crops, 2: 28-54
[6] Thaloor, D. 1999. Systemic administration of the NF-kappaB
inhibitor curcumin stimulates muscle regeneration after traumatic
injury. Am. J. Physiol., 277 (2pt 1): C320 – C329.
[7] Puwastien, P., T.E. Siong, J. Kantasubrata, G. Caven, R.R.
Felicionoand and K. Judprasong, 2011. Asean Manual of Food
Analysis. Regional centre of Asean Network of Food Data System.
Institute of Nutrition, Mahidol University Thailand, pp. 1-190.
[8] Wilkinson, L. 1996. Statistics, Systat for Windows. SPSS Inc., USA..
pp. 183-223
[9] Maha, B. 2013. Antidiabetic Potential of Turmeric with/without
Fermented Milk Enriched with Probiotics in Diabetic Rats. Am. J. of
Biomed and Life Sci., 1(1): 1-7
[10] Seo, K. L., M. S. Choi, U. J. Jung, H. J. Kim, J. Yeo, S. M. Jeon and
M. K. Lee, 2008. Effect of curcumin supplementation on blood
glucose, plasma insulin and glucose homeostasis related enzyme
activities in diabetic db/db mice. Mol. Nutr. Food Res., 52: 995-1004.
[11] Wickenberg, J., S. L. Ingemansson, J., and Hlebowicz. 2010. Effects
of Curcuma longa (turmeric) on postprandial plasma glucose and
insulin in healthy subjects. Nutrition J., 9: 43 (1- 5).
[12] Aggarwal, B. B., C. Sundaram, N. Malani and H. Ichikawa, 2007.
Curcumin: The Indian Solid Gold. Adv. Exp. Med. Biol., 595: 1-75
[13] Rivera-Espinoza, Y. and P. Muriel, 2009. Pharmacological actions of
curcumin in liver diseases or damage. Liver Int., 29: 1457-1466.
[14] Radwan, L., R.A. Hassan, E.M. Qota and H.M. Fayek. 2008. Effect of
Natural Antioxidant on Oxidative Stability of Eggs and Productive
and Reproductive Performance of Laying Hens. Int. J. Poult. Sci.,
7(2): 134-150.
[15] Reyes-Gordillo, K., J. Segovia, M. Shibayama, P. Vergara, M.G.
Moreno and P. Muriel, 2007. Curcumin protects against acute liver
damage in the rat by inhibiting NF-kappaB, proinflammatory
cytokines production and oxidative stress. Biochim. Biophys. Acta.,
1770: 989-996.
[16] Reyes-Gordillo, K., J. Segovia, M. Shibayama, V. Tsutsumi, P.
Vergara, M.G. Moreno and P. Muriel. 2008. Curcumin prevents and
reverses cirrhosis induced by bile duct obstruction or CCl4 in rats:
Role of TGF-beta modulation and oxidative stress. Role of TGF-beta
modulation and oxidative stress. Fundam. Clin. Pharmacol., 22: 417-
427.
[17] Burley, R. W., A. J. Evans and J. A. Pearson, 1993. Molecular aspects
of the synthesis and deposition of hens' egg yolk with special
reference to low density lipoprotein. Poult. Sci., 72: 850-855.
[18] Etches, R. J. 1996. Reproduction in Poultry. Singapore. CAB.
Internatiuonal, pp. 125-166
[19] Steven, L. 2004. Avian biochemistry and molecular biology.
Cmbridge University Press, UK, pp. 46-81.
[20] Saraswati, T. R., W. Manalu, R.E. Damiana and N. Kusumorini.
2013. Increased Egg Production of Japanese Quail (Cortunix
japonica) by Improving Liver Function Through Turmeric Powder
Supplementation. Int. J. Poultry Sci., 12 (10): 601-614.
[21] Chattopadhyay, I.K., U. Biswa, Bandyopadhyay and R. K. Banerjeeil,
2004. Turmeric and Curcumin: Biological action and medicinal
applications. Review article. Curr. Sci., 87: 44-53.
[22] Sreejayan, N. and M.N. Rao, 1996. Free radical scavenging activity of
curcuminoid. Drug Res., 46:169-171.
[23] Somchit, M.N., A. Zuraini, A. Bustamam, M.R. Sulaiman and R.
Nuratunlina, 2005. Protective activity of turmeric (Curcuma longa) in
paracetamol induced hepatotoxicity in rat. Int. J. Pharmacol., 1: 252-
256.
[24] Elkin, R. G., Z. Yan, Y. Zhong, S. S. Donkin, K. K. Buhma, J. A.
Story, J. J. Turek, R. E. Porter Jr, M. Anderson, R. Homan and R.S.
Newton, 1999. Select 3-hydroxy-3-methylglutarylcoenzym A
reductase inhibitors vary in their ability to reduce egg yolk cholesterol
levels in laying hens trough alteration of hepatic cholesterol
biosynthesis and plasma VLDL composition. J.Nutr., 129: 1010-1019.
[25] Babu, P.S., K. Srinivasan. 1997. Hypolipidemic action of curcumin,
the active principle of turmeric (Curcuma longa) in streptozotocin
induced diabetic rats. Mol. Cell Biochem., 166: 169–175.
[26] Kim, M. and Kim, Y. 2010.Hypocholesterolemic effects of curcumin
via up-regulation of cholesterol 7a-hydroxylase in rats fed a high
fatdiet. Nutr. Res.Pract., 4(3):191-195.
[27] Gylling, H. and T.A. Miettinen. 1995. The effect of cholesterol
absorption inhibition on low density lipoprotein cholesterol level.
Atherosclerosis, 117:305-308.
[28] Altmann, S.W., H.R. Davis Jr., L.J. Zhu, X. Yao, L.M. Hoos, G.
Tetzloff, S.P. Iyer, M. Maguire, A. Golovko and M.Zeng. 2004.
Niemann-Pick C1 Like 1protein is critical for intestinal cholesterol
absorption. Science, 303(5661): 1201-1204.
[29] Feng, D., Ohlsson, L. and D. Rui-Dong.2010.Curcumin inhibits
cholesterol uptake in Caco-2cells by down-regulation of NPC1L1
expression. Lipids in Health and Disease, 9: 40–45.
[30] Arafa, H.M. 2005.Curcumin attenuates diet-induced hypercholesterolemia
in rats. Med. Sci. Monit., 11: BR228– BR234
[31] Rao DS, Sekhara NC, Satyanarayana MN, Srinivasan M (1970).
Effect of curcumin on serum and liver cholesterol levels in the rat. J.
Nutr., 100: 1307–1315.
[32] Kuwabara, T., K.H. Han, N. Hashimoto, H. Yamauchi, K. Shimada,
M. Sekikawa and M. Fukushima. 2007. Tartary buckwheat sprout
powder lowers plasma cholesterol level in rats. J. Nutr. Sci. Vitaminol
(Tokyo), 53:501-7.
[33] Peschel D, Koerting R, Nass N (2007). Curcumin induces changes
expression of genes involved in cholesterol homeostasis. J. Nutr.
Biochem., 18: 113–119.
[34] Ramirez-Tortosa, M. C., M. D. Mesa, M. C. Aguilera, J. L. Quiles, L.
Baro and C. Ramirez-Tortosa.1999. Oral administration of a turmeric
extract inhibits LDL oxidation and has hypocholesterolemic effects in
rabbits with experimental atherosclerosis. Atherosclerosis, 147: 371–
378.
[35] Xu, J., Y. Fu and A. Chen. 2003. Activation of peroxisome
proliferator activated receptor-gamma contributes to the inhibitory
effects of curcumin on rat hepatic stellate cell growth. Am. J. Physiol.
Gastrointest, Liver Physiol., 285: G20–G30.
[36] Zheng, S. and A. Chen. 2006. Curcumin suppresses the expression of
extracellular matrix genes in activated hepatic stellate cells by
inhibiting gene expression of connective tissue growth factor. Am. J.
Physiol. Gastrointest, Liver Physiol., 290: G883–G893.
[37] Zhou, Y., S. Zheng, J. Lin, Q. J. Zhang and A. Chen. 2007. The
interruption of the PDGF and EGF signaling pathways by curcumin
stimulates gene expression of PPAR gamma in rat activated hepatic
stellate cell in vitro. Lab. Invest., 87: 488–498.
[38] Zheng, S., F. Yumei and A. Chen. 2007. De novo synthesis of
glutathione is a prerequisite for curcumin to inhibit hepatic stellate
cell (HSC) activation. Free Radic. Biol. Med., 43: 444–453.
[39] Park, E. J., C.H. Jeon, G. Ko, J. Kim and D. H. Sohn. 2000. Protective
effect of curcumin in rat liver injury induced by carbon tetrachloride.
J. Pharm.Pharmacol.,52: 437–440.
[40] Nanji, A. A., K. Jokelainen, G. L. Tipoe, A. Rahemtulla, P. Thomas
and Dannenberg, A. J. 2003. Curcumin prevents alcohol-induced liver
disease in rats by inhibiting the expression of NF-kappa B-dependent
genes. Am. J. Physiol. Gastrointest. Liver Physiol., 284: G321–G327.
[41] Fu, Y., S. Zheng, J. Lin, J. Ryerse, A. Chen. 2008. Curcumin protects
the rat liver from CCl4-caused injury and fibrogenesis by attenuating
oxidative stress and suppressing inflammation. Mol. Pharmacol.
73:399–409.
[42] Kang, Q. and Chen, A. 2009. Curcumin suppresses expression of lowdensity
lipoprotein (LDL) receptor, leading to the inhibition of LDLinduced
activation of hepatic stellate cells. Brit. J. Pharmac., 157:
1354–136.
[43] Saraswati, T. R., W. Manalu, D. R. Ekastuti and N. Kusumorini.
2013. The role of turmeric powder in lipid metabolism and its effect
on quality of the first quail’s egg. J. Indonesian Trop. Anim. Agric.
38: 123-130.
@article{"International Journal of Biological, Life and Agricultural Sciences:70261", author = "D. P. Rahardja and M. Rahman Hakim and V. Sri Lestari", title = "Egg Production Performance of Old Laying Hen Fed Dietary Turmeric Powder", abstract = "An experiment was conducted to elucidate the effects of turmeric powder supplementation on egg production performance of old laying hens (80 weeks of age). There were 40 hens of Hysex Brown strain used in the study. They were caged individually, and randomly divided into 4 treatment groups of diet containing 0 (control), 1, 2 and 4 % oven dried turmeric powder for 3 periods of 4 weeks; Egg production (% hen day) and feed intake of the 4 treatment groups at the commencement of the experiment were not significantly different. In addition to egg production performance (% and egg weight), feed and water intakes were measured daily, and cholesterol content of the whole egg was determined. The results indicated that feed intakes of the hen were significantly lowered when 4% turmeric powder supplemented, while there were no significant changes in water intakes. Egg production were significantly increased and maintained at a higher level by turmeric powder supplementation up to 4% compared with the control, while the weight of eggs were not significantly affected. The research markedly demonstrated that supplementation of turmeric powder up to 4% could improve and maintain egg production performance of the old laying hen at a higher level with a lower cholesterol content.
", keywords = "Curcumin, feed and water intake, old laying hen,
egg production.", volume = "9", number = "7", pages = "748-5", }
