Abstract: This paper seeks to give a general idea of the universe of project portfolio management, from its multidisciplinary nature, to the many challenges it raises, passing through the different techniques, models and tools used to solve the multiple problems known. It is intended to contribute to the clarification, with great depth, of the impacts and relationships involved in managing the projects- portfolio. It aims at proposing a technique for the project alignment with the organisational strategy, in order to select projects that later on will be considered in the analysis and selection of the portfolio. We consider the development of a methodology for assessing the project alignment index very relevant in the global market scenario. It can help organisations to gain a greater awareness of market dynamics, speed up the decision process and increase its consistency, thus enabling the strategic alignment and the improvement of the organisational performance.
Abstract: Innovations, especially technological, are considered
key-drivers for sustainable economic growth and competitiveness in
the globalised world. As such they should also play an important role
in the process of economical convergence inside the EU.
Unfortunately, the problem of insufficient innovation performance
concerns around half of the EU countries. Poland shows that a lack of
a consistent high-tech financing system constitutes a serious obstacle
for the development of innovative firms. In this article we will
evaluate these questions referring to the example of Ammono S.A., a
Polish company established to develop and commercialise an original
technology for the production of bulk GaN crystals. We will focus on
its efforts to accumulate the financial resources necessary at different
stages of its development. The purpose of this article is to suggest
possible ways to improve the national innovative system, which
would make it more competent in generating high-tech leaders.
Abstract: Nowadays, efficiency, effectiveness and economy are regarded as the main objectives of managers and the secret of the continuity of an organization in competing economy. In such competing settings, it is essential that the management of an organization has not been neglected and been obliged to identify quickly the opportunities for improving the operation of organization and remove the shortcomings of their managed system in order to use the opportunities for development. Operational auditing is a useful tool for system adjustment and leading an organization toward its objectives. Operational auditing is indeed a viewpoint which identifies the causes of insufficiencies, weaknesses and deficiencies of system and plans to eliminate them. Operational auditing is useful in the effectiveness and optimization of executive managers- decisions and increasing the efficiency and economy of their performance in the future and prevents the waste and incorrect use of resources. Evidence shows that operational auditing is used at a limited level in Iran. This matter raises some questions like the following ones in the minds. Why do a limited number of corporations use operational auditing? Which factors can guarantee its full implementation? What obstacles are there in its implementation? The purpose of this article is to determine executive objectives, the operation domain of operational auditing, the components of operational auditing and the executive obstacles to operational auditing in Iran.
Abstract: With the resource exhaustion, bad affections of human
activities and the awakening of the human rights, the corporate social
responsibility became popular corporate strategy achieving
sustainable development of both corporation and society. The issue of
Guideline of Chinese Corporate Social Responsibility Report
promotes greatly corporation to take social responsibility. This paper
built the index system according to this guideline and takes the textile
industry as an example, uses the analytical hierarchy process to
identify the weightings of different responsibilities of corporation to
guide the corporate social responsibility performance assessment.
Abstract: Sinc-collocation scheme is one of the new techniques
used in solving numerical problems involving integral equations. This
method has been shown to be a powerful numerical tool for finding
fast and accurate solutions. So, in this paper, some properties of the
Sinc-collocation method required for our subsequent development
are given and are utilized to reduce integral equation of the first
kind to some algebraic equations. Then convergence with exponential
rate is proved by a theorem to guarantee applicability of numerical
technique. Finally, numerical examples are included to demonstrate
the validity and applicability of the technique.
Abstract: In the past 20 years the economy of the Czech
Republic has experienced substantial changes. In the 1990s the
development was affected by the transformation which sought to
establish the right conditions for privatization and creation of
elementary market relations. In the last decade the characteristic
elements such as private ownership and corresponding institutional
framework have been strengthened. This development was marked by
the accession of the Czech Republic to the EU. The Czech Republic
is striving to reduce the difference between its level of economic
development and the quality of institutional framework in
comparison with other developed countries. The process of finding
the adequate solutions has been hampered by the negative impact of
the world financial crisis on the Czech Republic and the standard of
living of its inhabitants. This contribution seeks to address the
question of whether and to which extent the economic development
of the transitive Czech economy is affected by the change in
behaviour of households and their tendency to consumption, i.e. in
the sense of reduction or increase in demand for goods and services.
It aims to verify whether the increasing trend of household
indebtedness and decreasing trend of saving pose a significant risk in
the Czech Republic. At a general level the analysis aims to contribute
to finding an answer to the question of whether the debt increase of
Czech households is connected to the risk of "eating through" the
borrowed money and whether Czech households risk falling into a
debt trap. In addition to household indebtedness risks in the Czech
Republic the analysis will focus on identification of specifics of the
transformation phase of the Czech economy in comparison with the
EU countries, or selected OECD countries.
Abstract: The number of the companies accepting RFID in Korea
has been increased continuously due to the domestic development of
information technology. The acceptance of RFID by companies in
Korea enabled them to do business with many global enterprises in a
much more efficient and effective way. According to a survey[33,
p76], many companies in Korea have used RFID for inventory or
distribution manages. But, the use of RFID in the companies in Korea
is in the early stages and its potential value hasn-t fully been realized
yet. At this time, it would be very important to investigate the factors
that affect RFID acceptance. For this study, many previous studies
were referenced and some RFID experts were interviewed. Through
the pilot test, four factors were selected - Security Trust, Employee
Knowledge, Partner Influence, Service Provider Trust - affecting
RFID acceptance and an extended technology acceptance
model(e-TAM) was presented with those factors. The proposed model
was empirically tested using data collected from employees in
companies or public enterprises. In order to analyze some
relationships between exogenous variables and four variables in TAM,
structural equation modeling(SEM) was developed and SPSS12.0 and
AMOS 7.0 were used for analyses. The results are summarized as
follows: 1) security trust perceived by employees positively
influences on perceived usefulness and perceived ease of use; 2)
employee-s knowledge on RFID positively influences on only
perceived ease of use; 3) a partner-s influence for RFID acceptance
positively influences on only perceived usefulness; 4) service provider
trust very positively influences on perceived usefulness and perceived
ease of use 5) the relationships between TAM variables are the same as
the previous studies.
Abstract: Work-life balance has been acknowledged and
promoted for the sake of employee retention. It is essential for a
manager to realize the human resources situation within a company to
help employees work happily and perform at their best. This paper
suggests knowledge management and critical thinking are useful to
motivate employees to think about their work-life balance. A
qualitative case study is presented, which aimed to discover the
meaning of work-life balance-s meaning from the perspective of Thai
knowledge workers and how it affects their decision-making towards
work resignation. Results found three types of work-life balance
dimensions; a work- life balance including a workplace and a private
life setting, an organizational working life balance only, and a worklife
balance only in a private life setting. These aspects all influenced
the decision-making of the employees. Factors within a theme of an
organizational work-life balance were involved with systematic
administration, fair treatment, employee recognition, challenging
assignments to gain working experience, assignment engagement,
teamwork, relationship with superiors, and working environment,
while factors concerning private life settings were about personal
demands such as an increasing their salary or starting their own
business.
Abstract: According to the conception of personnel
management, human resource management requires efficient use of
human resources. This is ensured by various activities directed
towards the area of management. Among these activities there are for
example the recruitment of employees, development, strengthening
of relations, mutual inspiring, implementation of correct working
processes and systems used by individuals or groups.
Abstract: School experiences, family bonding and self-concept
had always been a crucial factor in influencing all aspects of a
student-s development. The purpose of this study is to develop and to
validate a priori model of self-concept among students. The study
was tested empirically using Structural Equation Modeling (SEM)
and Confirmatory Factor Analysis (CFA) to validate the structural
model. To address these concerns, 1167 students were randomly
selected and utilized the Cognitive Psycho-Social University of
Malaya instrument (2009).Resulted demonstrated there is indirect
effect from family bonding to self-concept through school
experiences among secondary school students as a mediator. Besides
school experiences, there is a direct effect from family bonding to
self-concept and family bonding to school experiences among
students.
Abstract: Mankind has entered into an extremely complex and
controversial stage of its development: the world is simultaneously
organized and chaoticized, globalized and localized, combined and
split. Analysts point out that globalization as a process of
strengthening economic, cultural, financial and other ties of states
cause many problems. In the economic sphere, it creates the danger
of growing gap between the states, in the sphere of politics it leads to
the weakening of political power and influence of nation-states.
Abstract: Currently is characterized production engineering
together with the integration of industrial automation and robotics
such very quick view of to manufacture the products. The production
range is continuously changing, expanding and producers have to be
flexible in this regard. It means that need to offer production
possibilities, which can respond to the quick change. Engineering
product development is focused on supporting CAD software, such
systems are mainly used for product design. That manufacturers are
competitive, it should be kept procured machines made available
capable of responding to output flexibility. In response to that
problem is the development of flexible manufacturing systems,
consisting of various automated systems. The integration of flexible
manufacturing systems and subunits together with product design and
of engineering is a possible solution for this issue. Integration is
possible through the implementation of CIM systems. Such a solution
and finding a hyphen between CAD and procurement system ICIM
3000 from Festo Co. is engaged in the research project and this
contribution. This can be designed the products in CAD systems and
watch the manufacturing process from order to shipping by the
development of methods and processes of integration, This can be
modeled in CAD systems products and watch the manufacturing
process from order to shipping to develop methods and processes of
integration, which will improve support for product design
parameters by monitoring of the production process, by creating of
programs for production using the CAD and therefore accelerates the
a total of process from design to implementation.
Abstract: Atherosclerosis was identified as a chronic inflammatory process resulting from interactions between plasma lipoproteins, cellular components (monocyte, macrophages, T lymphocytes, endothelial cells and smooth muscle cells) and the extracellular matrix of the arterial wall. Several types of genes were known to express during formation of atherosclerosis. This study is carried out to identify unknown differentially expressed gene (DEG) in atherogenesis. Rabbit’s aorta tissues were stained by H&E for histomorphology. GeneFishing™ PCR analysis was performed from total RNA extracted from the aorta tissues. The DNA fragment from DEG was cloned, sequenced and validated by Real-time PCR. Histomorphology showed intimal thickening in the aorta. DEG detected from ACP-41 was identified as cathepsin B gene and showed upregulation at week-8 and week-12 of atherogenesis. Therefore, ACP-based GeneFishing™ PCR facilitated identification of cathepsin B gene which was differentially expressed during development of atherosclerosis.
Abstract: Human genome is not only the evolutionary
summation of all advantageous events, but also houses lesions of
deleterious foot prints. A single gene mutation sometimes may
express multiple consequences in numerous tissues and a linear
relationship of the genotype and the phenotype may often be obscure.
ß Thalassemia minor, a transfusion independent mild anaemia,
coupled with environment among other factors may articulate into
phenotypic pleotropy with Hypocholesterolemia, Vitamin D
deficiency, Tissue hypoxia, Hyper-parathyroidism and Psychological
alterations. Occurrence of Pancreatic insufficiency, resultant
steatorrhoea, Vitamin-D (25-OH) deficiency (13.86 ngm/ml) with
Hypocholesterolemia (85mg/dl) in a 30 years old male ß Thal-minor
patient (Hemoglobin 11mg/dl with Fetal Hemoglobin 2.10%, Hb A2
4.60% and Hb Adult 84.80% and altered Hemogram) with increased
Para thyroid hormone (62 pg/ml) & moderate Serum Ca+2
(9.5mg/ml) indicate towards a cascade of phenotypic pleotropy
where the ß Thalassemia mutation ,be it in the 5’ cap site of the
mRNA , differential splicing etc in heterozygous state is effecting
several metabolic pathways. Compensatory extramedulary
hematopoiesis may not coped up well with the stressful life style of
the young individual and increased erythropoietic stress with high
demand for cholesterol for RBC membrane synthesis may have
resulted in Hypocholesterolemia.Oxidative stress and tissue hypoxia
may have caused the pancreatic insufficiency, leading to Vitamin D
deficiency. This may in turn have caused the secondary
hyperparathyroidism to sustain serum Calcium level. Irritability and
stress intolerance of the patient was a cumulative effect of the vicious
cycle of metabolic compromises. From these findings we propose
that the metabolic deficiencies in the ß Thalassemia mutations may
be considered as the phenotypic display of the pleotropy to explain
the genetic epidemiology.
According to the recommendations from the NIH Workshop on
Gene-Environment Interplay in Common Complex Diseases: Forging
an Integrative Model, study design of observations should be
informed by gene-environment hypotheses and results of a study
(genetic diseases) should be published to inform future hypotheses.
Variety of approaches is needed to capture data on all possible
aspects, each of which is likely to contribute to the etiology of
disease. Speakers also agreed that there is a need for development of
new statistical methods and measurement tools to appraise
information that may be missed out by conventional method where
large sample size is needed to segregate considerable effect.
A meta analytic cohort study in future may bring about significant
insight on to the title comment.
Abstract: A company CSR commitment, as stated in its Social
Report is, actually, perceived by its stakeholders?And in what
measure? Moreover, are stakeholders satisfied with the company
CSR efforts? Indeed, business returns from Corporate Social
Responsibility (CSR) practices, such as company reputation and
customer loyalty, depend heavily on how stakeholders perceive the
company social conduct. In this paper, we propose a methodology to
assess a company CSR commitment based on Global Reporting
Initiative (GRI) indicators, Content Analysis and a CSR positioning
matrix. We evaluate three aspects of CSR: the company commitment
disclosed through its Social Report; the company commitment
perceived by its stakeholders; the CSR commitment that stakeholders
require to the company. The positioning of the company under study
in the CSR matrix is based on the comparison among the three
commitment aspects (disclosed, perceived, required) and it allows
assessment and development of CSR strategies.
Abstract: The objective of this paper is twofold: (1) discuss and
analyze the successful case studies worldwide, and (2) identify the
similarities and differences of case studies worldwide. Design
methodology/approach: The nature of this research is mainly method
qualitative (multi-case studies, literature review). This investigation
uses ten case studies, and the data was mainly collected and
organizational documents from the international countries. Finding:
The finding of this research can help incubator manager, policy
maker and government parties for successful implementation.
Originality/value: This paper contributes to the current literate review
on the best practices worldwide. Additionally, it presents future
perspective for academicians and practitioners.
Abstract: This paper deals with the evaluation of flow properties
of polymeric matrix with natural animal fillers. Technical university
of Liberec cooperates on the long-term development of “green
materials“ that should replace conventionally used materials
(especially in automotive industry). Natural fibres (of animal and
plant origin) from all over the world are collected and adapted
(drying, cutting etc.) for extrusion processing. Inside the extruder
these natural additives are blended with polymeric (synthetic and
biodegradable - PLA) matrix and created compound is subsequently
cut for pellets in the wet way. These green materials with unique
recipes are then studied and their mechanical, physical and
processing properties are determined. The main goal of this research
is to develop new ecological materials very similar to unfilled
polymers. In this article the rheological behaviour of chosen natural
animal fibres is introduced considering their shape and surface that
were observed with use of SEM microscopy.
Abstract: Bioinformatics and Cheminformatics use computer as disciplines providing tools for acquisition, storage, processing, analysis, integrate data and for the development of potential applications of biological and chemical data. A chemical database is one of the databases that exclusively designed to store chemical information. NMRShiftDB is one of the main databases that used to represent the chemical structures in 2D or 3D structures. SMILES format is one of many ways to write a chemical structure in a linear format. In this study we extracted Antimicrobial Structures in SMILES format from NMRShiftDB and stored it in our Local Data Warehouse with its corresponding information. Additionally, we developed a searching tool that would response to user-s query using the JME Editor tool that allows user to draw or edit molecules and converts the drawn structure into SMILES format. We applied Quick Search algorithm to search for Antimicrobial Structures in our Local Data Ware House.
Abstract: This study was designed to investigate the role of serum nitric oxide and sialic acid in the development of diabetic nephropathy as disease marker. Total 210 diabetic patients (age and sex matched) were selected followed by informed consent and divided into four groups (70 each) as I: control; II: diabetic; III: diabetic hypertensive; IV: diabetic nephropathy. The blood samples of all subjects were collected and analyzed for serum nitric oxide, sialic acid, fasting blood glucose, serum urea, creatinine, HbA1c and GFR. The BMI, systolic and diastolic blood pressures, blood glucose, HbA1c and serum sialic acid levels were high (p
Abstract: In this article we present a methodology which
enables preschool and primary school unlanguaged children to
remember words, phrases and texts with the help of graphic signs -
letters, syllables and words. Reading for a child becomes a support
for speech development. Teaching is based on the principle "from
simple to complex", "a letter - a syllable - a word - a proposal - a
text." Availability of multi-level texts allows using this methodology
for working with children who have different levels of speech
development.