Abstract: Statistical analysis of electrophysiological recordings
obtained under, e.g. tactile, stimulation frequently suggests participation
in the network dynamics of experimentally unobserved “hidden"
neurons. Such interneurons making synapses to experimentally
recorded neurons may strongly alter their dynamical responses to
the stimuli. We propose a mathematical method that formalizes this
possibility and provides an algorithm for inferring on the presence
and dynamics of hidden neurons based on fitting of the experimental
data to spike trains generated by the network model. The model
makes use of Integrate and Fire neurons “chemically" coupled
through exponentially decaying synaptic currents. We test the method
on simulated data and also provide an example of its application to
the experimental recording from the Dorsal Column Nuclei neurons
of the rat under tactile stimulation of a hind limb.
Abstract: As research performance in academia is treated as one of indices for national competency, many countries devote much attention and resources to increasing their research performance. Understand the research trend is the basic step to improve the research performance. The goal of this research is to design an analysis system to evaluate research trends from analyzing data from different countries. In this paper, information system researches in Taiwan and other countries, including Asian countries and prominent countries represented by the Group of Eight (G8) is used as example. Our research found the trends are varied in different countries. Our research suggested that Taiwan-s scholars can pay more attention to interdisciplinary applications and try to increase their collaboration with other countries, in order to increase Taiwan's competency in the area of information science.
Abstract: Lateral-torsional buckling (LTB) is one of the
phenomenae controlling the ultimate bending strength of steel Ibeams
carrying distributed loads on top flange. Built-up I-sections
are used as main beams and distributors. This study investigates the
ultimate bending strength of such beams with sections of different
classes including slender elements. The nominal strengths of the
selected beams are calculated for different unsupported lengths
according to the Provisions of the American Institute of Steel
Constructions (AISC-LRFD). These calculations are compared with
results of a nonlinear inelastic study using accurate FE model for this
type of loading. The goal is to investigate the performance of the
provisions for the selected sections. Continuous distributed load at
the top flange of the beams was applied at the FE model.
Imperfections of different values are implemented to the FE model to
examine their effect on the LTB of beams at failure, and hence, their
effect on the ultimate strength of beams. The study also introduces a
procedure for evaluating the performance of the provisions compared
with the accurate FEA results of the selected sections. A simplified
design procedure is given and recommendations for future code
updates are made.
Abstract: A new tool path planning method for 5-axis flank
milling of a globoidal indexing cam is developed in this paper. The
globoidal indexing cam is a practical transmission mechanism due
to its high transmission speed, accuracy and dynamic performance.
Machining the cam profile is a complex and precise task. The profile
surface of the globoidal cam is generated by the conjugate contact
motion of the roller. The generated complex profile surface is usually
machined by 5-axis point-milling method. The point-milling method
is time-consuming compared with flank milling. The tool path for
5-axis flank milling of globoidal cam is developed to improve the
cutting efficiency. The flank milling tool path is globally optimized
according to the minimum zone criterion, and high accuracy is
guaranteed. The computational example and cutting simulation finally
validate the developed method.
Abstract: In today-s economy plant engineering faces many
challenges. For instance the intensifying competition in this business
is leading to cost competition and needs for a shorter time-to-market.
To remain competitive companies need to make their businesses
more profitable by implementing improvement programs such as
standardization projects. But they have difficulties to tap their full
economic potential for various reasons. One of them is non-holistic
planning and implementation of standardization projects. This paper
describes a new conceptual framework - the layer-model. The model
combines and expands existing proven approaches in order to
improve design, implementation and management of standardization
projects. Based on a holistic approach it helps to systematically
analyze the effects of standardization projects on different business
layers and enables companies to better seize the opportunities offered
by standardization.
Abstract: This study examined the toxicological effects and
safety of polypeptide k isolated from the seeds of Momordica
charantia in laboratory rats. 30 male Sprague Dawley rats (12 weeks
old, bodyweight 180-200 g) were randomly divided into 3 groups
(1000 mg/kg, 500 mg and 0 mg/kg). Rats were acclimatized to
laboratory conditions for 7 days and at day 8 rats were dosed orally
with polypeptide k (in 2% DMSO/normal saline) and the controls
received the dosed vehicle only. Rats were then observed for 72
hours before sacrificed. Rats were anaesthetized by pentobarbital
(50 mg/kg ip) and 2-3.0 mL of blood was taken by cardiac puncture
and rats were scarified by anaesthetic overdose. Immediately, organs
(heart, lungs, liver, kidneys) were weigh and taken for histology.
Organ sections were then evaluated by a histopathologist. Serum
samples were assayed for liver functions (ALT and γ-GT) and kidney
functions (BUN and creatinine). All rats showed normal behavior
after the dosing and no statistical changes were observed in all blood
parameters and organ weight. Histological examinations revealed
normal organ structures. In conclusion, dosing of rats up to 1000
mg/kg did not have any effects on the rat behavior, liver or kidney
functions nor histology of the selected organs.
Abstract: Discrete Cosine Transform (DCT) based transform coding is very popular in image, video and speech compression due to its good energy compaction and decorrelating properties. However, at low bit rates, the reconstructed images generally suffer from visually annoying blocking artifacts as a result of coarse quantization. Lapped transform was proposed as an alternative to the DCT with reduced blocking artifacts and increased coding gain. Lapped transforms are popular for their good performance, robustness against oversmoothing and availability of fast implementation algorithms. However, there is no proper study reported in the literature regarding the statistical distributions of block Lapped Orthogonal Transform (LOT) and Lapped Biorthogonal Transform (LBT) coefficients. This study performs two goodness-of-fit tests, the Kolmogorov-Smirnov (KS) test and the 2- test, to determine the distribution that best fits the LOT and LBT coefficients. The experimental results show that the distribution of a majority of the significant AC coefficients can be modeled by the Generalized Gaussian distribution. The knowledge of the statistical distribution of transform coefficients greatly helps in the design of optimal quantizers that may lead to minimum distortion and hence achieve optimal coding efficiency.
Abstract: Anxiety is a common disorder that attacks many people in society and often accompanied by physiological sensations such as tachycardia, chest pain, shortness of breath, insensitivity and etc. The purpose of this study is to characterize the putative anxiolytic-like effects of DEV (dichloromethane extracts of valerian) using the elevated plus maze (EPM) in rats. DEV was dissolved in DMSO and orally administered at different doses to adult male wistar rats, 0.5, 1.5 and 3 hours before behavioral evaluation in an EPM respectively. Control rats were treated with an equal volume of DMSO. Single treatment of DEV (at 0.1,0.2. 0.3, and 0.4 g/kg) significantly increased time-spent and arm entries into open arms of EPM versus control groups (p
Abstract: The study aimed to identify the logical structure of
data and particularities of developing and testing a website designed
for selling farm products through online auctions.
The research is based on a short literature review in the field and
exploratory trials of some successful models from other industries, in
order to identify the advantages of using such tool, as well as the
optimal structure and functionality of an auction portal. In the last
part, the study focuses on the results of testing the website by the
potential beneficiaries.
Conclusions of the study underlines that the particularities of some
agricultural products could raise difficulties in the process of selling
them through online auctions, but the use of such system it is
perceived to bring significant improvements in the supply chain.
The results of scientific investigations require a more detailed
study regarding the importance of using quality standards for
agricultural products sold via online auction, the impact that
implementation of an online payment system could have on trade
with agricultural products and problems which could arise in using
the website in different countries.
Abstract: TTV is an unenveloped circular single-stranded DNA
virus with a diameter of 30-32 nm that first was described in 1997 in
Japan. TTV was detected in various populations without proven
pathology, including blood donors and in patients with chronic HBV
and HCV hepatitis. The aim of this study was to determine the
prevalence of TTV DNA in Iranian patients with chronic hepatitis B
and C. Viral TTV-DNA was studied in 442 samples (202 with HBV,
138 with HCV and 102 controls) collected from west south of Iran.
All extracted serum DNA was amplified by TTV ORF1 gene specific
primers using the semi nested PCR technique. TTV DNA was
detected in the serum of 8.9% and 10.8% patients with chronic
hepatitis B and C, respectively. Prevalence of TTV-DNA in the serum
of 102 controls was 2.9%. Results showed significant relation of TTV
with HBV and HCV in patients by using T test examination (P
Abstract: In the framework of the image compression by
Wavelet Transforms, we propose a perceptual method by
incorporating Human Visual System (HVS) characteristics in the
quantization stage. Indeed, human eyes haven-t an equal sensitivity
across the frequency bandwidth. Therefore, the clarity of the
reconstructed images can be improved by weighting the quantization
according to the Contrast Sensitivity Function (CSF). The visual
artifact at low bit rate is minimized. To evaluate our method, we use
the Peak Signal to Noise Ratio (PSNR) and a new evaluating criteria
witch takes into account visual criteria. The experimental results
illustrate that our technique shows improvement on image quality at
the same compression ratio.
Abstract: According to dramatic growth of internet services, an easy and prompt service deployment has been important for internet service providers to successfully maintain time-to-market. Before global service deployment, they have to pay the big cost for service evaluation to make a decision of the proper system location, system scale, service delay and so on. But, intra-Lab evaluation tends to have big gaps in the measured data compared with the realistic situation, because it is very difficult to accurately expect the local service environment, network congestion, service delay, network bandwidth and other factors. Therefore, to resolve or ease the upper problems, we propose multiple cloud based GPES Broker system and use case that helps internet service providers to alleviate the above problems in beta release phase and to make a prompt decision for their service launching. By supporting more realistic and reliable evaluation information, the proposed GPES Broker system saves the service release cost and enables internet service provider to make a prompt decision about their service launching to various remote regions.
Abstract: Enterprise Architecture (EA) is a framework for description, coordination and alignment of all activities across the organization in order to achieve strategic goals using ICT enablers. A number of EA-compatible frameworks have been developed. We, in this paper, mainly focus on Federal Enterprise Architecture Framework (FEAF) since its reference models are plentiful. Among these models we are interested here in its business reference model (BRM). The test process is one important subject of an EA project which is to somewhat overlooked. This lack of attention may cause drawbacks or even failure of an enterprise architecture project. To address this issue we intend to use International Software Testing Qualification Board (ISTQB) framework and standard test suites to present a method to improve EA testing process. The main challenge is how to communicate between the concepts of EA and ISTQB. In this paper, we propose a method for integrating these concepts.
Abstract: to simulate the phenomenon of electronic transport in semiconductors, we try to adapt a numerical method, often and most frequently it’s that of Monte Carlo. In our work, we applied this method in the case of a ternary alloy semiconductor GaInP in its cubic form; The Calculations are made using a non-parabolic effective-mass energy band model. We consider a band of conduction to three valleys (ΓLX), major of the scattering mechanisms are taken into account in this modeling, as the interactions with the acoustic phonons (elastic collisions) and optics (inelastic collisions). The polar optical phonons cause anisotropic collisions, intra-valleys, very probable in the III-V semiconductors. Other optical phonons, no polar, allow transitions inter-valleys. Initially, we present the full results obtained by the simulation of Monte Carlo in GaInP in stationary regime. We consider thereafter the effects related to the application of an electric field varying according to time, we thus study the transient phenomenon which make their appearance in ternary material
Abstract: In recent decade's tourism industry is one of main
reasons of the social and economical development for many
countries; so these countries try to gain more portion of it for
themselves. The excessive natural and cultural touristy potentialities
in Iran made this country to be one of the most attractive sightseeing
areas, although; Iran has got the lowest rate of tourists. Khark Island
is about 32 km. It is a beautiful coral reef coast; about 98% of oil
export has been done through this place. The ecotourism
potentialities of Khark and Kharko Islands (about 3.7km far from
Khark) are the reason to consider ecotourism and the main activity in
these islands which is exporting oil at the same time. This article
refers to way of measuring the geographical coordination of the
place, and the potentialities, ecotourism attraction of the islands and
introduces some ideas in order to expand tourism in the islands.
Abstract: Protein-protein interactions (PPI) play a crucial role in many biological processes such as cell signalling, transcription, translation, replication, signal transduction, and drug targeting, etc. Structural information about protein-protein interaction is essential for understanding the molecular mechanisms of these processes. Structures of protein-protein complexes are still difficult to obtain by biophysical methods such as NMR and X-ray crystallography, and therefore protein-protein docking computation is considered an important approach for understanding protein-protein interactions. However, reliable prediction of the protein-protein complexes is still under way. In the past decades, several grid-based docking algorithms based on the Katchalski-Katzir scoring scheme were developed, e.g., FTDock, ZDOCK, HADDOCK, RosettaDock, HEX, etc. However, the success rate of protein-protein docking prediction is still far from ideal. In this work, we first propose a more practical measure for evaluating the success of protein-protein docking predictions,the rate of first success (RFS), which is similar to the concept of mean first passage time (MFPT). Accordingly, we have assessed the ZDOCK bound and unbound benchmarks 2.0 and 3.0. We also createda new benchmark set for protein-protein docking predictions, in which the complexes have experimentally determined binding affinity data. We performed free energy calculation based on the solution of non-linear Poisson-Boltzmann equation (nlPBE) to improve the binding mode prediction. We used the well-studied thebarnase-barstarsystem to validate the parameters for free energy calculations. Besides,thenlPBE-based free energy calculations were conducted for the badly predicted cases by ZDOCK and ZRANK. We found that direct molecular mechanics energetics cannot be used to discriminate the native binding pose from the decoys.Our results indicate that nlPBE-based calculations appeared to be one of the promising approaches for improving the success rate of binding pose predictions.
Abstract: The study entitled “The Construction of Interactive
Computer Multimedia Instruction on Basic Japanese Vocabulary"
was aimed: 1) To construct the interactive computer multimedia
instruction on Basic Japanese Vocabulary, 2) To find out
multimedia-s quality, 3) To examine the student-s satisfaction and 4)
To study the learning achievement in Basic Japanese vocabulary. The
sampling group used in this study was composed of 40 1st year
student in Educational Communications and Technology Department,
Faculty of Industrial Education and Technology, King Mongkut-s
University of Technology Thonburi, in the academic year 2553 B.E.
(2010). According to research results, we found that 1). The quality
assessment by 3 mass media experts was at 4.72 on average or at high
level. 2) In terms of contents, the evaluation by 3 experts was at 4.81
on average or at high level. 3) In terms of achievement, there was a
statistical significance between before and after the treatment at the
.05 level. 4) The satisfaction of students towards the interactive
computer multimedia Instruction on “Basic Japanese Vocabulary"
was 4.35 on average, or at high level.
Abstract: In contrast to existing methods which do not take into account multiconnectivity in a broad sense of this term, we develop mathematical models and highly effective combination (BIEM and FDM) numerical methods of calculation of stationary and quasistationary temperature field of a profile part of a blade with convective cooling (from the point of view of realization on PC). The theoretical substantiation of these methods is proved by appropriate theorems. For it, converging quadrature processes have been developed and the estimations of errors in the terms of A.Ziqmound continuity modules have been received. For visualization of profiles are used: the method of the least squares with automatic conjecture, device spline, smooth replenishment and neural nets. Boundary conditions of heat exchange are determined from the solution of the corresponding integral equations and empirical relationships. The reliability of designed methods is proved by calculation and experimental investigations heat and hydraulic characteristics of the gas turbine first stage nozzle blade.
Abstract: Synchronization between 0.1 Hz oscillations in heart rate and blood pressure is studied and its change during vertical tilt is evaluated in 37 myocardial infarction patients. Two groups of patients are identified with decreased and increased, respectively, synchronization of the studied oscillations as a response to a tilt test. It is shown that assessment of synchronization of 0.1 Hz oscillations as a response to vertical tilt can be used as a guideline for selecting optimal dose of beta-blocker treatment in post-myocardial infarction patients.
Abstract: The information on the Web increases tremendously.
A number of search engines have been developed for searching Web
information and retrieving relevant documents that satisfy the
inquirers needs. Search engines provide inquirers irrelevant
documents among search results, since the search is text-based rather
than semantic-based. Information retrieval research area has
presented a number of approaches and methodologies such as
profiling, feedback, query modification, human-computer interaction,
etc for improving search results. Moreover, information retrieval has
employed artificial intelligence techniques and strategies such as
machine learning heuristics, tuning mechanisms, user and system
vocabularies, logical theory, etc for capturing user's preferences and
using them for guiding the search based on the semantic analysis
rather than syntactic analysis. Although a valuable improvement has
been recorded on search results, the survey has shown that still
search engines users are not really satisfied with their search results.
Using ontologies for semantic-based searching is likely the key
solution. Adopting profiling approach and using ontology base
characteristics, this work proposes a strategy for finding the exact
meaning of the query terms in order to retrieve relevant information
according to user needs. The evaluation of conducted experiments
has shown the effectiveness of the suggested methodology and
conclusion is presented.