Abstract: EcoDam is an adenine-N6 DNA methyltransferase
that methylates the GATC sites in the Escherichia coli genome.
DNA-adenine methylation is not present in higher eukaryotes
including humans. These observations raise the possibility that dam
inhibitors may be used as anti-microbial agents. Polyphosphate
(Poly(P)) is an important metabolite and signaling molecule in
prokaryotes and eukaryotes. Here, by using gel retardation
experiments to investigate the competition of DNA binding by
EcoDam in the presence of polyphosphate, we found that Poly (P)
strongly interferes with DNA binding by EcoDam, while same
concentration of monophosphate does not. In addition, we
demonstrated that Poly (P) binding inhibits the activity of EcoDam
and our results suggest that Poly (P) led to strong inhibition of the
EcoDam catalytic activity, while monophosphate had only moderate
effect.
Abstract: The overriding goal of software engineering is to
provide a high quality system, application or a product. To achieve
this goal, software engineers must apply effective methods coupled
with modern tools within the context of a mature software process
[2]. In addition, it is also must to assure that high quality is realized.
Although many quality measures can be collected at the project
levels, the important measures are errors and defects. Deriving a
quality measure for reusable components has proven to be
challenging task now a days. The results obtained from the study are
based on the empirical evidence of reuse practices, as emerged from
the analysis of industrial projects. Both large and small companies,
working in a variety of business domains, and using object-oriented
and procedural development approaches contributed towards this
study. This paper proposes a quality metric that provides benefit at
both project and process level, namely defect removal efficiency
(DRE).
Abstract: This paper describes the design and development of pico-hydro generation system using consuming water distributed to houses. Water flow in the domestic pipes has kinetic energy that potential to generate electricity for energy storage purposes in addition to the routine activities such as laundry, cook and bathe. The inherent water pressure and flow inside the pipe from utility-s main tank that used for those usual activities is also used to rotate small scale hydro turbine to drive a generator for electrical power generation. Hence, this project is conducted to develop a small scale hydro generation system using consuming water distributed to houses as an alternative electrical energy source for residential use.
Abstract: This paper proposes an alternative control mechanism
for an interactive Pan/Tilt/Zoom (PTZ) camera control system.
Instead of using a mouse or a joystick, the proposed mechanism
utilizes a Nintendo Wii remote and infrared (IR) sensor bar. The Wii
remote has buttons that allows the user to control the movement of a
PTZ camera through Bluetooth connectivity. In addition, the Wii
remote has a built-in motion sensor that allows the user to give
control signals to the PTZ camera through pitch and roll movement.
A stationary IR sensor bar, placed at some distance away opposite the
Wii remote, enables the detection of yaw movement. In addition, the
Wii remote-s built-in IR camera has the ability to detect its spatial
position, and thus generates a control signal when the user moves the
Wii remote. Some experiments are carried out and their performances
are compared with an industry-standard PTZ joystick.
Abstract: In this paper, some problem formulations of dynamic object parameters recovery described by non-autonomous system of ordinary differential equations with multipoint unshared edge conditions are investigated. Depending on the number of additional conditions the problem is reduced to an algebraic equations system or to a problem of quadratic programming. With this purpose the paper offers a new scheme of the edge conditions transfer method called by conditions shift. The method permits to get rid from differential links and multipoint unshared initially-edge conditions. The advantage of the proposed approach is concluded by capabilities of reduction of a parametric identification problem to essential simple problems of the solution of an algebraic system or quadratic programming.
Abstract: This paper presents a VLSI design approach of a highspeed
and real-time 2-D Discrete Wavelet Transform computing. The
proposed architecture, based on new and fast convolution approach,
reduces the hardware complexity in addition to reduce the critical
path to the multiplier delay. Furthermore, an advanced twodimensional
(2-D) discrete wavelet transform (DWT)
implementation, with an efficient memory area, is designed to
produce one output in every clock cycle. As a result, a very highspeed
is attained. The system is verified, using JPEG2000
coefficients filters, on Xilinx Virtex-II Field Programmable Gate
Array (FPGA) device without accessing any external memory. The
resulting computing rate is up to 270 M samples/s and the (9,7) 2-D
wavelet filter uses only 18 kb of memory (16 kb of first-in-first-out
memory) with 256×256 image size. In this way, the developed design
requests reduced memory and provide very high-speed processing as
well as high PSNR quality.
Abstract: According to the density of the chips, designers are
trying to put so any facilities of computational and storage on single
chips. Along with the complexity of computational and storage
circuits, the designing, testing and debugging become more and more
complex and expensive. So, hardware design will be built by using
very high speed hardware description language, which is more
efficient and cost effective. This paper will focus on the
implementation of 32-bit ALU design based on Verilog hardware
description language. Adder and subtracter operate correctly on both
unsigned and positive numbers. In ALU, addition takes most of the
time if it uses the ripple-carry adder. The general strategy for
designing fast adders is to reduce the time required to form carry
signals. Adders that use this principle are called carry look- ahead
adder. The carry look-ahead adder is to be designed with combination
of 4-bit adders. The syntax of Verilog HDL is similar to the C
programming language. This paper proposes a unified approach to
ALU design in which both simulation and formal verification can
co-exist.
Abstract: An implementation of current-mode multiphase sinusoidal oscillators is presented. Using CFTA-based lossy integrators, odd and odd/even phase systems can be realized with following advantages. The condition of oscillation and frequency of oscillation can be orthogonally tuned. The high output impedances facilitate easy driving an external load without additional current buffers. The proposed MSOs provide odd or even phase signals that are equally spaced in phase and equal amplitude. The circuit requires one CFTA, one resistor and one grounded capacitor per phase without additional current amplifier. The results of PSPICE simulations using CMOS CFTA are included to verify theory.
Abstract: Chicken feathers were used as biosorbent for Pb
removal from aqueous solution. In this paper, the kinetics and
equilibrium studies at several pH, temperature, and metal
concentration values are reported. For tested conditions, the Pb
sorption capacity of this poultry waste ranged from 0.8 to 8.3 mg/g.
Optimal conditions for Pb removal by chicken feathers have been
identified. Pseudo-first order and pseudo-second order equations
were used to analyze the experimental data. In addition, the sorption
isotherms were fitted to classical Langmuir and Freundlich models.
Finally, thermodynamic parameters for the sorption process have
been determined. In summary, the results showed that chicken
feathers are an alternative and promising sorbent for the treatment of
effluents polluted by Pb ions.
Abstract: In an effort to understand the preliminary effects of aerodynamic stress on alveolar epithelial cells, we developed a multifluidic cell culture platform capable of supporting alveolar cultures at an air-liquid interface under constant air flow and exposure to varying pressure stimuli on the apical side while providing nourishment on the basolateral plane. Our current study involved utilizing the platform to study the effect of basement membrane coating and addition of dexamethasone on cellular response to pressure in A549 and H441 alveolar epithelial cells.
Abstract: Titanium nitride (TiN) has been synthesized using the
sheet plasma negative ion source (SPNIS). The parameters used for
its effective synthesis has been determined from previous
experiments and studies. In this study, further enhancement of the
deposition rate of TiN synthesis and advancement of the SPNIS
operation is presented. This is primarily achieved by the addition of
Sm-Co permanent magnets and a modification of the configuration in
the TiN deposition process. The magnetic enhancement is aimed at
optimizing the sputtering rate and the sputtering yield of the process.
The Sm-Co permanent magnets are placed below the Ti target for
better sputtering by argon. The Ti target is biased from –250V to –
350V and is sputtered by Ar plasma produced at discharge current of
2.5–4A and discharge potential of 60–90V. Steel substrates of
dimensions 20x20x0.5mm3 were prepared with N2:Ar volumetric
ratios of 1:3, 1:5 and 1:10. Ocular inspection of samples exhibit
bright gold color associated with TiN. XRD characterization
confirmed the effective TiN synthesis as all samples exhibit the (200)
and (311) peaks of TiN and the non-stoichiometric Ti2N (220) facet.
Cross-sectional SEM results showed increase in the TiN deposition
rate of up to 0.35μm/min. This doubles what was previously obtained
[1]. Scanning electron micrograph results give a comparative
morphological picture of the samples. Vickers hardness results gave
the largest hardness value of 21.094GPa.
Abstract: This paper estimates the economic values of
household preference for enhanced solid waste disposal services in
Malaysia. The contingent valuation (CV) method estimates an
average additional monthly willingness-to-pay (WTP) in solid waste
management charges of Ôé¼0.77 to 0.80 for improved waste disposal
services quality. The finding of a slightly higher WTP from the
generic CV question than that of label-specific, further reveals a
higher WTP for sanitary landfill, at Ôé¼0.90, than incineration, at Ôé¼0.63.
This suggests that sanitary landfill is a more preferred alternative.
The logistic regression estimation procedure reveals that household-s
concern of where their rubbish is disposed, age, ownership of house,
household income and format of CV question are significant factors
in influencing WTP.
Abstract: With deep development of software reuse, componentrelated
technologies have been widely applied in the development of
large-scale complex applications. Component identification (CI) is
one of the primary research problems in software reuse, by analyzing
domain business models to get a set of business components with high
reuse value and good reuse performance to support effective reuse.
Based on the concept and classification of CI, its technical stack is
briefly discussed from four views, i.e., form of input business models,
identification goals, identification strategies, and identification
process. Then various CI methods presented in literatures are
classified into four types, i.e., domain analysis based methods,
cohesion-coupling based clustering methods, CRUD matrix based
methods, and other methods, with the comparisons between these
methods for their advantages and disadvantages. Additionally, some
insufficiencies of study on CI are discussed, and the causes are
explained subsequently. Finally, it is concluded with some
significantly promising tendency about research on this problem.
Abstract: To explore pipelines is one of various bio-mimetic
robot applications. The robot may work in common buildings such as
between ceilings and ducts, in addition to complicated and massive
pipeline systems of large industrial plants. The bio-mimetic robot finds
any troubled area or malfunction and then reports its data. Importantly,
it can not only prepare for but also react to any abnormal routes in the
pipeline. The pipeline monitoring tasks require special types of mobile
robots. For an effective movement along a pipeline, the movement of
the robot will be similar to that of insects or crawling animals. During
its movement along the pipelines, a pipeline monitoring robot has an
important task of finding the shapes of the approaching path on the
pipes. In this paper we propose an effective solution to the pipeline
pattern recognition, based on the fuzzy classification rules for the
measured IR distance data.
Abstract: Cell formation is the first step in the design of cellular
manufacturing systems. In this study, a general purpose
computational scheme employing a hybrid tabu search algorithm as
the core is proposed to solve the cell formation problem and its
variants. In the proposed scheme, great flexibilities are left to the
users. The core solution searching algorithm embedded in the scheme
can be easily changed to any other meta-heuristic algorithms, such as
the simulated annealing, genetic algorithm, etc., based on the
characteristics of the problems to be solved or the preferences the
users might have. In addition, several counters are designed to control
the timing of conducting intensified solution searching and diversified
solution searching strategies interactively.
Abstract: This article presents a resistorless current-mode firstorder allpass filter based on second generation current controlled current conveyors (CCCIIs). The features of the circuit are that: the pole frequency can be electronically controlled via the input bias current: the circuit description is very simple, consisting of 2 CCCIIs and single grounded capacitor, without any external resistors and component matching requirements. Consequently, the proposed circuit is very appropriate to further develop into an integrated circuit. Low input and high output impedances of the proposed configuration enable the circuit to be cascaded in current-mode without additional current buffers. The PSpice simulation results are depicted. The given results agree well with the theoretical anticipation. The application example as a current-mode quadrature oscillator is included.
Abstract: This paper reviews recent studies and particularly the
effects of Climate Change in the North Tropical Atlantic by studying
atmospheric conditions that prevailed in 2005 ; Coral Bleaching
HotSpot and Hurricane Katrina. In the aim to better understand and
estimate the impact of the physical phenomenon, i.e. Thermal
Oceanic HotSpot (TOHS), isotopic studies of δ18O and δ13C on
marine animals from Guadeloupe (French Caribbean Island) were
carried out. Recorded measures show Sea Surface Temperature (SST)
up to 35°C in August which is much higher than data recorded by
NOAA satellites 32°C. After having reviewed the process that led to
the creation of Hurricane Katrina which hit New Orleans in August
29, 2005, it will be shown that the climatic conditions in the
Caribbean from August to October 2005 have influenced Katrina
evolution. This TOHS is a combined effect of various phenomenon
which represent an additional factor to estimate future climate
changes.
Abstract: This paper examines whether or not immigration has a positive influence on the duration of unemployment, in a macroeconomic perspective. We analyse also whether the degree of labor market integration can influence migration. The integration of immigrants into the labor market is a recurrence theme in the work on the economic consequences of immigration. However, to our knowledge, no researchers have studied the impact of immigration on unemployment duration, and vice versa. With two methodology of research (panel estimations (OLS and 2SLS) and panel cointegration techniques), we show that migration seems to influence positively the short-term unemployment and negatively long-term unemployment, for 14 OECD destination countries. In addition, immigration seems to be conditioned by the structural and institutional characteristics of the labour market.
Abstract: Recently, there have been considerable efforts towards the convergence between P2P and Grid computing in order to reach a solution that takes the best of both worlds by exploiting the advantages that each offers. Augmenting the peer-to-peer model to the services of the Grid promises to eliminate bottlenecks and ensure greater scalability, availability, and fault-tolerance. The Grid Information Service (GIS) directly influences quality of service for grid platforms. Most of the proposed solutions for decentralizing the GIS are based on completely flat overlays. The main contributions for this paper are: the investigation of a novel resource discovery framework for Grid implementations based on a hierarchy of structured peer-to-peer overlay networks, and introducing a discovery algorithm utilizing the proposed framework. Validation of the framework-s performance is done via simulation. Experimental results show that the proposed organization has the advantage of being scalable while providing fault-isolation, effective bandwidth utilization, and hierarchical access control. In addition, it will lead to a reliable, guaranteed sub-linear search which returns results within a bounded interval of time and with a smaller amount of generated traffic within each domain.
Abstract: Support vector machines (SVMs) are considered to be
the best machine learning algorithms for minimizing the predictive
probability of misclassification. However, their drawback is that for
large data sets the computation of the optimal decision boundary is a
time consuming function of the size of the training set. Hence several
methods have been proposed to speed up the SVM algorithm. Here
three methods used to speed up the computation of the SVM
classifiers are compared experimentally using a musical genre
classification problem. The simplest method pre-selects a random
sample of the data before the application of the SVM algorithm. Two
additional methods use proximity graphs to pre-select data that are
near the decision boundary. One uses k-Nearest Neighbor graphs and
the other Relative Neighborhood Graphs to accomplish the task.