Abstract: Malathion (ML) is a well known pesticide commonly
used in many agricultural and non-agricultural processes. Its toxicity
has been attributed primarily to the accumulation of acetylcholine
(Ach) at nerve junctions, due to the inhibition of acetylcholinesterase
(AChE). The aim of the current research was to study the protective
effect of the melissa plant extract against reproductive impairment
induced by malathion in 32 male albino rats, and the biological
experiment was divided into four groups (8 in each) that given
malathion (27 mg/kg; 1/50 of the LD50 for an oral dose) and/or
Melissa officinalis (MO) extract (200mg/kg/day) by gavages
technique. The sperm counts, sperm motility, sperm morphology,
FSH, LH, and testosterone levels had been determined in testes
homogenate at the end of the experiment. It is worthy to report that,
rats treated with melissa extract did not show a significant difference
when compared with the control group, while rats given malathion
alone had significantly lower sperm count, sperm motility, and
significantly higher abnormal sperm numbers, than the untreated
control rats as well as having significantly lower serum FSH, LH, and
testosterone levels compared with the control group. Administrations
of melissa extract restore all mentioned histological parameters
towards the control group and the melissa extract had a strong
positive protective effect against malathion toxicity. Results the of
biological parameters were confirmed by the histological
examination of rat testes and indicated that, both control and melissa
groups showing normal seminiferous tubules, while malathion group
testicular tissues had necrosis, edema in the seminiferous tubules and
degeneration of spermatogonial cells lining the seminiferous tubules
with incomplete spermatogenesis. The use of melissa against
malathion improved the histological picture and showing normal
seminiferous tubules with complete spermatogenesis and almost there
was no histopathological changes could be noted.
Abstract: Pomegranate (Punica granatum L.) is an ancient fruit of great medical interest and rich source of antioxidants. Pesticides as dimethoate play a crucial role in the occurrence many diseases in plants, animal and human. Therefore the ability of Pomegranate (Punica granatum L.) to alleviate hepatotoxicity induced by organophosphate pesticide dimethoate was investigated. Albino male rats were divided randomly into 4 groups and kept at 7 animals per group in an environmentally controlled condition for 6 weeks. The first group was served as a control group (basal diet), the second group fed on basal diet supplemented with 5% freeze dried pomegranate seeds, the third group fed on 20 ppm dimethoate contaminated diet and the last group fed on dimethoate contaminated diet supplemented with 5% freeze dried pomegranate seeds. The results revealed that administration of dimethoate caused high significant increased in liver functions: alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) activities as well as lipid peroxide (malonaldhyde, MDA); on the other hand high significant decreased on glutathione (GSH), glutathione peroxidase (GPx), albumin and total protein were observed. However addition of 5% freeze dried pomegranate seeds significantly improved all previously mentioned parameters. These results indicate the dimethoate induced hepatotoxicity and highlight the protective effect of pomegranate seeds as a potential protective agent against dimethoate induced hepatotoxicity. This may be attributed to the powerful antioxidants (polyphenols, total phenols, and total flavonoids) which present in high levels in pomegranate as well as improving the immunity by activation of antioxidant enzymes GSH and GPx.
Abstract: In this paper we make a temperature investigations in
two type of superposed crimped connections using experimental
determinations. All the samples use 8 copper wire 7.1 x 3 mm2
crimped by two methods: the first method uses one crimp indents and
the second is a proposed method with two crimp indents. The ferrule
is a parallel one. We study the influence of number and position of
crimp indents. The samples are heated in A.C. current at different
current values until steady state heating regime. After obtaining of
temperature values, we compare them and present the conclusion.
Abstract: This study aimed at designing and developing a
mechanical force gauge for the square watermelon mold for the first
time. It also tried to introduce the square watermelon characteristics
and its production limitations. The mechanical force gauge
performance and the product itself were also described. There are
three main designable gauge models: a. hydraulic gauge, b. strain
gauge, and c. mechanical gauge. The advantage of the hydraulic
model is that it instantly displays the pressure and thus the force
exerted by the melon. However, considering the inability to measure
forces at all directions, complicated development, high cost, possible
hydraulic fluid leak into the fruit chamber and the possible influence
of increased ambient temperature on the fluid pressure, the
development of this gauge was overruled. The second choice was to
calculate pressure using the direct force a strain gauge. The main
advantage of these strain gauges over spring types is their high
precision in measurements; but with regard to the lack of conformity
of strain gauge working range with water melon growth, calculations
were faced with problems. Finally the mechanical pressure gauge has
advantages, including the ability to measured forces and pressures on
the mold surface during melon growth; the ability to display the peak
forces; the ability to produce melon growth graph thanks to its
continuous force measurements; the conformity of its manufacturing
materials with the required physical conditions of melon growth; high
air conditioning capability; the ability to permit sunlight reaches the
melon rind (no yellowish skin and quality loss); fast and
straightforward calibration; no damages to the product during
assembling and disassembling; visual check capability of the product
within the mold; applicable to all growth environments (field,
greenhouses, etc.); simple process; low costs and so forth.
Abstract: In many communication and signal processing
systems, it is highly desirable to implement an efficient narrow-band
filter that decimate or interpolate the incoming signals. This paper
presents hardware efficient compensated CIC filter over a narrow
band frequency that increases the speed of down sampling by using
multiplierless decimation filters with polyphase FIR filter structure.
The proposed work analyzed the performance of compensated CIC
filter on the bases of the improvement of frequency response with
reduced hardware complexity in terms of no. of adders and
multipliers and produces the filtered results without any alterations.
CIC compensator filter demonstrated that by using compensation
with CIC filter improve the frequency response in passed of interest
26.57% with the reduction in hardware complexity 12.25%
multiplications per input sample (MPIS) and 23.4% additions per
input sample (APIS) w.r.t. FIR filter respectively.
Abstract: Multipotent mesenchymal stromal cells (MSCs)
possess immunomodulatory properties. The effect of MSCs on the
crucial cellular immunity compartment – T-cells is of a special
interest. It is known that MSC tissue niche and expected milieu of
their interaction with T- cells are characterized by low oxygen
concentration, whereas the in vitro experiments usually are carried
out at a much higher ambient oxygen (20%). We firstly evaluated
immunomodulatory effects of MSCs on T-cells at tissue-related
oxygen (5%) after interaction implied cell-to-cell contacts and
paracrine factors only. It turned out that MSCs under reduced oxygen
can effectively suppress the activation and proliferation of PHAstimulated
T-cells and can provoke decrease in the production of
proinflammatory and increase in anti-inflammatory cytokines. In
hypoxia some effects were amplified (inhibition of proliferation, antiinflammatory
cytokine profile shift). This impact was more evident
after direct cell-to-cell interaction; lack of intercellular contacts could
revoke the potentiating effect of hypoxia.
Abstract: This paper presents the variation of the dynamic
characteristics of a spindle with the change of bearing preload. The
correlations between the variation of bearing preload and fundamental
modal parameters were first examined by conducting vibration tests on
physical spindle units. Experimental measurements show that the
dynamic compliance and damping ratio associated with the
dominating modes were affected to vary with variation of the bearing
preload. When the bearing preload was slightly deviated from a
standard value, the modal frequency and damping ability also vary to
different extent, which further enable the spindle to perform with
different compliance. For the spindle used in this study, a standard
preload value set on bearings would enable the spindle to behave a
higher stiffness as compared with others with a preload variation. This
characteristic can be served as a reference to examine the variation of
bearing preload of spindle in assemblage or operation.
Abstract: We used high-precision Global Positioning System
(GPS) to geodetically constrain the motion of stations in the
Darjiling-Sikkim Himalayan (DSH) wedge and examine the
deformation at the Indian-Tibetan plate boundary using IGS
(International GPS Service) fiducial stations. High-precision GPS
based displacement and velocity field was measured in the DSH
between 1997 and 2009. To obtain additional insight north of the
Indo-Tibetan border and in the Darjiling-Sikkim-Tibet (DaSiT)
wedge, published velocities from four stations J037, XIGA, J029 and
YADO were also included in the analysis. India-fixed velocities or
the back-slip was computed relative to the pole of rotation of the
Indian Plate (Latitude 52.97 ± 0.22º, Longitude - 0.30 ± 3.76º, and
Angular Velocity 0.500 ± 0.008º/ Myr) in the DaSiT wedge.
Dislocation modelling was carried out with the back-slip to model the
best possible solution of a finite rectangular dislocation or the
causative fault based on dislocation theory that produced the
observed back-slip using a forward modelling approach. To find the
best possible solution, three different models were attempted. First,
slip along a single thrust fault, then two thrust faults and in finally,
three thrust faults were modelled to simulate the back-slip in the
DaSiT wedge. The three-fault case bests the measured displacements
and is taken as the best possible solution.
Abstract: Analysis of real life problems often results in linear
systems of equations for which solutions are sought. The method to
employ depends, to some extent, on the properties of the coefficient
matrix. It is not always feasible to solve linear systems of equations
by direct methods, as such the need to use an iterative method
becomes imperative. Before an iterative method can be employed
to solve a linear system of equations there must be a guaranty that
the process of solution will converge. This guaranty, which must
be determined apriori, involve the use of some criterion expressible
in terms of the entries of the coefficient matrix. It is, therefore,
logical that the convergence criterion should depend implicitly on the
algebraic structure of such a method. However, in deference to this
view is the practice of conducting convergence analysis for Gauss-
Seidel iteration on a criterion formulated based on the algebraic
structure of Jacobi iteration. To remedy this anomaly, the Gauss-
Seidel iteration was studied for its algebraic structure and contrary
to the usual assumption, it was discovered that some property of the
iteration matrix of Gauss-Seidel method is only diagonally dominant
in its first row while the other rows do not satisfy diagonal dominance.
With the aid of this structure we herein fashion out an improved
version of Gauss-Seidel iteration with the prospect of enhancing
convergence and robustness of the method. A numerical section is
included to demonstrate the validity of the theoretical results obtained
for the improved Gauss-Seidel method.
Abstract: It is known that residual welding deformations give
negative effect to processability and operational quality of welded
structures, complicating their assembly and reducing strength.
Therefore, selection of optimal technology, ensuring minimum
welding deformations, is one of the main goals in developing a
technology for manufacturing of welded structures.
Through years, JSC SSTC has been developing a theory for
estimation of welding deformations and practical activities for
reducing and compensating such deformations during welding
process. During long time a methodology was used, based on analytic
dependence. This methodology allowed defining volumetric changes
of metal due to welding heating and subsequent cooling. However,
dependences for definition of structures deformations, arising as a
result of volumetric changes of metal in the weld area, allowed
performing calculations only for simple structures, such as units, flat
sections and sections with small curvature. In case of complex 3D
structures, estimations on the base of analytic dependences gave
significant errors.
To eliminate this shortage, it was suggested to use finite elements
method for resolving of deformation problem. Here, one shall first
calculate volumes of longitudinal and transversal shortenings of
welding joints using method of analytic dependences and further,
with obtained shortenings, calculate forces, which action is
equivalent to the action of active welding stresses. Further, a finiteelements
model of the structure is developed and equivalent forces
are added to this model. Having results of calculations, an optimal
sequence of assembly and welding is selected and special measures to
reduce and compensate welding deformations are developed and
taken.
Abstract: This paper analyzes innovation trends in South Korea
by means of the number of patent applications filed by residents and
nonresidents during the period 1965 to 2012. Making use of patent
data released by the World Intellectual Property Organization
(WIPO), we search for the presence of multiple structural changes in
patent application series in this country. These changes may suggest
that firms’ innovative activity has been modified as a result of
implementing some science, technology and innovation (STI)
policies. Accordingly, the new regulations implemented in this
country in the last decades have influenced its innovative activity.
The question conducting this research is thus how STI policies in
South Korea have influenced its innovation activity. The results
confirm the existence of multiple structural changes in the series of
patent applications resulting from alternative STI policies
implemented during these years.
Abstract: Enzyme activity was evaluated in the intestine of
juvenile dourado (Salminus brasiliensis) fed with diets containing 0,
10 or 20% of lyophilized bovine colostrum (LBC) inclusion for either
30 or 60 days. The intestinal enzymes acid and alkaline phosphatase
(ACP and ALP, respectively), non-specific esterase (NSE), lipase
(LIP), dipeptidyl aminopeptidase IV (DAP IV) and leucine
aminopeptidase (LAP) were studied using histochemistry in four
intestinal segments (S1, S2, S3 and posterior intestine). Weak
proteolitic activity was observed in all intestinal segments for DAP
IV and LAP. The activity of NSE and LIP was also weak in all
intestines, except for the moderate activity of NSE in the S2 of 20%
LBC group after 30 days and in the S1 of 0% LBC group after 60
days. The ACP was detected only in the S2 and S3 of the 10% LBC
group after 30 days. Moderate and strong staining was observed in
the first three intestinal segments for ALP and weak activity in the
posterior intestine. The activity of DAP IV, LAP and ALP were also
present in the cytoplasm of the enterocytes. In the present results,
bovine colostrum feeding did not cause alterations in activity of
intestinal enzymes.
Abstract: This study investigates the effect of moisture
conditioning on the Indirect Tensile Strength (ITS) of asphalt
concrete. As a first step, cylindrical samples of 100 mm diameter and
50 mm thick were prepared using a Superpave gyratory compactor.
Next, the samples were conditioned using Moisture Induced
Susceptibility Test (MIST) device at different numbers of moisture
conditioning cycles. In the MIST device, samples are subjected water
pressure through the sample pores cyclically. The MIST conditioned
samples were tested for ITS. Results show that the ITS does not
change significantly with MIST conditioning at the specific pressure
and cycles adopted in this study.
Abstract: Disasters are quite experienced in our days. They are
caused by floods, landslides, and building fires that is the main
objective of this study. To cope with these unexpected events,
precautions must be taken to protect human lives. The emphasis on
disposal work focuses on the resolution of the evacuation problem in
case of no-notice disaster. The problem of evacuation is listed as a
dynamic network flow problem. Particularly, we model the
evacuation problem as an earliest arrival flow problem with load
dependent transit time. This problem is classified as NP-Hard. Our
challenge here is to propose a metaheuristic solution for solving the
evacuation problem. We define our objective as the maximization of
evacuees during earliest periods of a time horizon T. The objective
provides the evacuation of persons as soon as possible. We
performed an experimental study on emergency evacuation from the
tunisian children’s hospital. This work prompts us to look for
evacuation plans corresponding to several situations where the
network dynamically changes.
Abstract: Osteoporosis is a common multifactorial disease with
a strong genetic component characterized by reduced bone mass and
increased risk of fractures. Genetic factors play an important role in
the pathogenesis of osteoporosis. The aim of our study was to
identify the genotype and allele distribution of T245G polymorphism
in OPG gene in Slovak postmenopausal women. A total of 200
unrelated Slovak postmenopausal women with diagnosed
osteoporosis and 200 normal controls were genotyped for T245G
(rs3134069) polymorphism of OPG gene. Genotyping was performed
using the Custom Taqman®SNP Genotyping assays. Genotypes and
alleles frequencies showed no significant differences (p=0.5551;
p=0.6022). The results of the present study confirm the importance of
T245G polymorphism in OPG gene in the pathogenesis of
osteoporosis.
Abstract: Second line antiretroviral therapy (ART) regimen is
used when patients fail their first line regimen. There are many
factors such as non-adherence, drug resistance as well as virological
and immunological failure that lead to second line highly active
antiretroviral therapy (HAART) regimen treatment failure. This study
was aimed at determining predictor factors to treatment failure with
second line HAART and analyzing median survival time.
An observational, retrospective study was conducted in Sungai
Buloh Hospital (HSB) to assess current status of HIV patients treated
with second line HAART regimen. Convenience sampling was used
and 104 patients were included based on the study’s inclusion and
exclusion criteria. Data was collected for six months i.e. from July
until December 2013. Data was then analysed using SPSS version 18.
Kaplan-Meier and Cox regression analyses were used to measure
median survival times and predictor factors for treatment failure.
The study population consisted mainly of male subjects, aged 30-
45 years, who were heterosexual, and had HIV infection for less than
6 years. The most common second line HAART regimen given was
lopinavir/ritonavir (LPV/r)-based combination. Kaplan-Meier
analysis showed that patients on LPV/r demonstrated longer median
survival times than patients on indinavir/ritonavir (IDV/r) based
combination (p
Abstract: Image segmentation process based on mathematical morphology has been studied in the paper. It has been established from the first principles of the morphological process, the entire segmentation is although a nonlinear signal processing task, the constituent wise, the intermediate steps are linear, bilinear and conformal transformation and they give rise to a non linear affect in a cumulative manner.
Abstract: The paper deals with the importance of information flow for providing of defined level of customer service in the firms. Setting of the criteria for the selection and implementation of logistics information system is a prerequisite for ensuring of the flow of information in firms. The decision on the selection and implementation of logistics information system is linked to the investment costs and operating costs, which are included in the total logistics costs. The article also deals with the conclusions of the research focused on the logistics information system selection in companies in the Czech Republic.
Abstract: Strontium hexaferrite (SrFe12O19; Sr-ferrite) is one of
the well-known materials for permanent magnets. In this study, Mtype
strontium ferrite was prepared by following the conventional
ceramic method from steelmaking by-product. Initial materials;
SrCO3 and by-product, were mixed together in the composition of
SrFe12O19 in different Sr/Fe ratios. The mixtures of these raw
materials were dry-milled for 6h. The blended powder was presintered
(i.e. calcination) at 1000°C for different times periods, then
cooled down to room temperature. These pre-sintered samples were
re-milled in a dry atmosphere for 1h and then fired at different
temperatures in atmospheric conditions, and cooled down to room
temperature. The produced magnetic powder has a dense hexagonal
grain shape structure. The calculated energy product values for the
produced samples ranged from 0.3 to 2.4 MGOe.
Abstract: The aim of this paper is to create a proposal for determining the costs of logistics processes by using process-oriented calculation methods. The traditional approach is that logistics costs are part of manufacturing overhead which is usually calculated as a percentage surcharge. Therefore in the traditional approach it is not obvious where and in which activities costs were incurred. So it is impossible to trace logistics costs to products. Our point of view is trying to fix or at least improve this issue. Another benefit of applying the process approach is identification of logistics processes which are otherwise part of manufacturing overhead. In the first part this paper describes the development of process-oriented methods over time. The next part shows the possibility of implementing the process-oriented method called Prozesskostenrechnung to logistics processes. The conclusion summarizes advantages and disadvantages of using this method in logistics.