Abstract: Tumour suppressors are key participants in the
prevention of cancer. Regulation of their expression through
miRNAs is important for comprehensive translation inhibition of
tumour suppressors and elucidation of carcinogenesis mechanisms.
We studies the possibility of 1521 miRNAs to bind with 873 mRNAs
of human tumour suppressors using RNAHybrid 2.1 and ERNAhybrid
programmes. Only 978 miRNAs were found to be
translational regulators of 812 mRNAs, and 61 mRNAs did not have
any miRNA binding sites. Additionally, 45.9% of all miRNA binding
sites were located in coding sequences (CDSs), 33.8% were located
in 3' untranslated region (UTR), and 20.3% were located in the
5'UTR. MiRNAs binding with more than 50 target mRNAs and
mRNAs binding with several miRNAs were selected. Hsa-miR-5096
had 15 perfectly complementary binding sites with mRNAs of 14
tumour suppressors. These newly indentified miRNA binding sites
can be used in the development of medicines (anti-sense therapies)
for cancer treatment.
Abstract: In this study, the dispersed model is used to predict
gas phase concentration, liquid drop concentration. The venturi
scrubber efficiency is calculated by gas phase concentration. The
modified model has been validated with available experimental data
of Johnstone, Field and Tasler for a range of throat gas velocities,
liquid to gas ratios and particle diameters and is used to study the
effect of some design parameters on collection efficiency.
Abstract: A frequency grouping approach for multi-channel
instantaneous blind source separation (I-BSS) of convolutive
mixtures is proposed for a lower net residual inter-symbol
interference (ISI) and inter-channel interference (ICI) than the
conventional short-time Fourier transform (STFT) approach. Starting
in the time domain, STFTs are taken with overlapping windows to
convert the convolutive mixing problem into frequency domain
instantaneous mixing. Mixture samples at the same frequency but
from different STFT windows are grouped together forming unique
frequency groups.
The individual frequency group vectors are input to the I-BSS
algorithm of choice, from which the output samples are dispersed
back to their respective STFT windows. After applying the inverse
STFT, the resulting time domain signals are used to construct the
complete source estimates via the weighted overlap-add method
(WOLA). The proposed algorithm is tested for source deconvolution
given two mixtures, and simulated along with the STFT approach to
illustrate its superiority for fairly motionless sources.
Abstract: An actual power plant, which is the power plant of Iron and Steel Factory at Misurata city in Libya , has been modeled using Matlab in order to compare its results to the actual results of the actual cycle. This paper concentrates on two factors:
a- The comparison between exergy losses in the actual cycle and the modeled cycle.
b- The effect of extracting pressure on temperature water at boiler inlet.
Closed heat exchangers used in this plant have been substituted by open heat exchangers in the current study of the modeled power plant and the required changes in the pressure have been considered. In the following investigation the two points mentioned above are taken in consideration.
Abstract: Since large power transformers are the most
expensive and strategically important components of any power
generator and transmission system, their reliability is crucially
important for the energy system operation. Also, Circuit breakers are
very important elements in the power transmission line so monitoring
the events gives a knowledgebase to determine time to the next
maintenance. This paper deals with the introduction of the
comparative method of the state estimation of transformers and
Circuit breakers using continuous monitoring of voltage, current.
This paper gives details a new method based on wavelet to apparatus
insulation monitoring. In this paper to insulation monitoring of
transformer, a new method based on wavelet transformation and
neutral point analysis is proposed. Using the EMTP tools, fault in
transformer winding and the detailed transformer winding model
were simulated. The current of neutral point of winding was analyzed
by wavelet transformation. It is shown that the neutral current of the
transformer winding has useful information about fault in insulation
of the transformer.
Abstract: Accounts of language acquisition differ significantly in their treatment of the role of prediction in language learning. In particular, nativist accounts posit that probabilistic learning about words and word sequences has little to do with how children come to use language. The accuracy of this claim was examined by testing whether distributional probabilities and frequency contributed to how well 3-4 year olds repeat simple word chunks. Corresponding chunks were the same length, expressed similar content, and were all grammatically acceptable, yet the results of the study showed marked differences in performance when overall distributional frequency varied. It was found that a distributional model of language predicted the empirical findings better than a number of other models, replicating earlier findings and showing that children attend to distributional probabilities in an adult corpus. This suggested that language is more prediction-and-error based, rather than on abstract rules which nativist camps suggest.
Abstract: Intradiscal and intervertebral pressure transducers
were developed. They were used to map the pressures in the nucleus
and within the annulus of the human spinal segments. Their stressrelaxation
were recorded over a period of time for nucleus
pressure, applied load, and peripherial strain against time. The
results show that for normal discs, pressures in the nucleus are
viscoelastic in nature with the applied compressive load.
Mechanical strains which develop around the periphery of the
vertebral body are also viscoelastic with the applied compressive
load. Applied compressive load against time also shows viscoelastic
behavior. However, annulus does not respond viscoelastically with
the applied load. It showed a linear response to compressive loading.
Abstract: A novel concept to balance and tradeoff between
make-to-stock and make-to-order has been hybrid MTS/MTO production context. One of the most important decisions involved in
the hybrid MTS/MTO environment is determining whether a product
is manufactured to stock, to order, or hybrid MTS/MTO strategy. In this paper, a model based on analytic network process is developed to tackle the addressed decision. Since the regarded decision deals with
the uncertainty and ambiguity of data as well as experts- and
managers- linguistic judgments, the proposed model is equipped with
fuzzy sets theory. An important attribute of the model is its generality due to diverse decision factors which are elicited from the
literature and developed by the authors. Finally, the model is validated by applying to a real case study to reveal how the proposed
model can actually be implemented.
Abstract: Among all geo-hydrological relationships, rainfallrunoff
relationship is of utmost importance in any hydrological
investigation and water resource planning. Spatial variation, lag time
involved in obtaining areal estimates for the basin as a whole can
affect the parameterization in design stage as well as in planning
stage. In conventional hydrological processing of data, spatial aspect
is either ignored or interpolated at sub-basin level. Temporal
variation when analysed for different stages can provide clues for its
spatial effectiveness. The interplay of space-time variation at pixel
level can provide better understanding of basin parameters.
Sustenance of design structures for different return periods and their
spatial auto-correlations should be studied at different geographical
scales for better management and planning of water resources.
In order to understand the relative effect of spatio-temporal
variation in hydrological data network, a detailed geo-hydrological
analysis of Betwa river catchment falling in Lower Yamuna Basin is
presented in this paper. Moreover, the exact estimates about the
availability of water in the Betwa river catchment, especially in the
wake of recent Betwa-Ken linkage project, need thorough scientific
investigation for better planning. Therefore, an attempt in this
direction is made here to analyse the existing hydrological and
meteorological data with the help of SPSS, GIS and MS-EXCEL
software. A comparison of spatial and temporal correlations at subcatchment
level in case of upper Betwa reaches has been made to
demonstrate the representativeness of rain gauges. First, flows at
different locations are used to derive correlation and regression
coefficients. Then, long-term normal water yield estimates based on
pixel-wise regression coefficients of rainfall-runoff relationship have
been mapped. The areal values obtained from these maps can
definitely improve upon estimates based on point-based
extrapolations or areal interpolations.
Abstract: Location-based services (LBS) exploit the known
location of a user to provide services dependent on their geographic
context and personalized needs [1].
The development and arrival of broadband mobile data networks
supported with mobile terminals equipped with new location
technologies like GPS have finally created opportunities for
implementation of LBS applications. But, from the other side,
collecting location information data in general raises privacy
concerns.
This paper presents results from two surveys of LBS acceptance in
Croatia. The first survey was administered on 181 students, and the
second extended survey involved pattern of 180 Croatian citizens.
We developed questionnaire which consists of descriptions of 15
different applications with scale which measures perceptions and
attitudes of users towards these applications.
We report the results to identify potential commercial applications
for LBS in B2C segment. Our findings suggest that some types of
applications like emergency&safety services and navigation have
significantly higher rate of acceptance than other types.
Abstract: The purpose of this paper is to shed light on the
controversial subject of tax incentives to promote regional
development. Although extensive research has been conducted, a
review of the literature gives an inconclusive answer to whether
economic incentives are effective. One reason is the fact that for
some researchers “effective" means the significant location of new
firms in targeted areas, while for others the creation of jobs
regardless if new firms are arriving in a significant fashion. We
present this dichotomy by analyzing a tax incentive program via both
alternatives: location and job creation. The contribution of the paper
is to inform policymakers about the potential opportunities and
pitfalls when designing incentive strategies. This is particularly
relevant, given that both the US and Europe have been promoting
incentives as a tool for regional economic development.
Abstract: The biological activity of A. pullulans isolates against
species of the genus Fusarium, bacteria of the genus Azotobacter and
pseudomonads colonizing wheat kernels was evaluated. A field
experiment was carried out in 2009-2011, in north-eastern Poland.
Winter wheat (cv. Bogatka) plants were sprayed with a cell
suspension of A. pullulans at a density of 106 - 108 per cm3 water at
the stem elongation stage and the heading stage. Untreated plants
served as control. The abundance of epiphytic yeasts, bacteria of the
genus Azotobacter, pseudomonads and Fusarium pathogens on wheat
grain was estimated at harvest and after six months’ storage. The
average size of yeast communities was significantly greater on wheat
kernels treated with a cell suspension of A. pullulans, compared with
control samples. In 2010-2011, biological control reduced the
abundance of some species of the genus Fusarium.
Abstract: A new observer based fault detection and diagnosis
scheme for predicting induction motors- faults is proposed in this
paper. Prediction of incipient faults, using different variants of
Kalman filter and their relative performance are evaluated. Only soft
faults are considered for this work. The data generation, filter
convergence issues, hypothesis testing and residue estimates are
addressed. Simulink model is used for data generation and various
types of faults are considered. A comparative assessment of the
estimates of different observers associated with these faults is
included.
Abstract: The higher compounded growth rates coupled with
favourable demographics in emerging markets portend abundant
opportunities for multinational organizations. With many
organizations competing for talent in these growing markets, their
ability to succeed will depend on their understanding of local
workforce needs and aspirations. Using data from the Towers Watson
2010 Global Workforce Study, this paper highlights differences in
employee engagement, turnover risks, and attraction and retention
drivers between the two markets. Apart from looking at the
traditional drivers of employee engagement, the study also explores
the value placed by employees on elements like a strong senior
leadership, managerial capabilities and career advancement
opportunities. Results reveal that emerging markets employees seem
to be more engaged and value the non-traditional elements more
highly than the developed markets employees.
Abstract: The Kowsar dam supply water for different usages
such as drinking, industrial, agricultural and aquaculture farms
usages and located next to the city of Dehdashat in Kohgiluye and
Boyerahmad province in southern Iran. There are some towns and
villages on the Kowsar dam watersheds, which Dehdasht and Choram
are the most important and populated cities in this area. The study
was undertaken to assess the status of water quality in the urban areas
of the Kowsar dam. A total of 28 water samples were collected from
6 stations on surface water and 1 station from groundwater on the
watershed of the Kowsar dam. All the samples were analyzed for Ni
concentration using standard procedures. The results were compared
with other national and international standards. Among the analyzed
samples, as the maximum value of Nickel (0.01 mg/L) was observed
on the station 2 at the autumn 2010, all the samples analyzed were
within the maximum admissible limits by the United States
Environmental Protection Agency, EU, WHO and the Iranian. In
general results of the present study have shown that a Ni mean value
of station No. 2 with 0.006 mg/L is higher than the other stations. Ni
level of all samples and stations have had normal values and this is an
indication of pollution potential and hazards because of human
activity and waste water of towns in the areas, which can effect on
human health implications in future. This research, therefore,
recommends the government and other responsible authorities to take
suitable improving measures in the Kowsar dam watersheds.
Abstract: The article examines an opportunity of corruption
restriction exercised by international business community in Russia.
Integration of Russian economy into the international business does
not reduce corruption inside the country. Foreign actors investing in
Russia under the condition of obtaining their required rates of returns
will be reluctant to harm their investments by involving into anticorruption
activities. Furthermore, many Russian firms- competitive
advantage could be directly related to their corruption connections. In
this case, foreign investments would only accentuate corrupt
companies- success by supporting them financially
Abstract: Nano MgO has been synthesized by hydration and
dehydration method by modifies the commercial MgO. The prepared
MgO had been investigated as a heterogeneous base catalyst for
transesterification process for biodiesel production using palm oil.
TGA, FT-IR and XRD results obtained from this study lie each other
and proved in the formation of nano MgO from decomposition of
Mg(OH)2. This study proved that the prepared nano MgO was a
better base transesterification catalyst compared to commercial MgO.
The nano MgO calcined at 600ºC had gives the highest conversion of
51.3% of palm oil to biodiesel.
Abstract: In a state-of-the-art industrial production line of
photovoltaic products the handling and automation processes are of
particular importance and implication. While processing a fully
functional crystalline solar cell an as-cut photovoltaic wafer is subject
to numerous repeated handling steps. With respect to stronger
requirements in productivity and decreasing rejections due to defects
the mechanical stress on the thin wafers has to be reduced to a
minimum as the fragility increases by decreasing wafer thicknesses.
In relation to the increasing wafer fragility, researches at the
Fraunhofer Institutes IPA and CSP showed a negative correlation
between multiple handling processes and the wafer integrity. Recent
work therefore focused on the analysis and optimization of the dry
wafer stack separation process with compressed air. The achievement
of a wafer sensitive process capability and a high production
throughput rate is the basic motivation in this research.
Abstract: In aerospace applications, interactions of airflow with
aircraft structures can result in undesirable structural deformations.
This structural deformation in turn, can be predicted if the natural
modes of the structure are known. This can be achieved through
conventional modal testing that requires a known excitation force in
order to extract these dynamic properties. This technique can be
experimentally complex because of the need for artificial excitation
and it is also does not represent actual operational condition. The
current work presents part of research work that address the practical
implementation of operational modal analysis (OMA) applied to a
cantilevered hybrid composite plate employing single contactless
sensing system via laser vibrometer. OMA technique extracts the
modal parameters based only on the measurements of the dynamic
response. The OMA results were verified with impact hammer modal
testing and good agreement was obtained.
Abstract: Ants are fascinating creatures that demonstrate the
ability to find food and bring it back to their nest. Their ability as a
colony, to find paths to food sources has inspired the development of
algorithms known as Ant Colony Systems (ACS). The principle of
cooperation forms the backbone of such algorithms, commonly used
to find solutions to problems such as the Traveling Salesman
Problem (TSP). Ants communicate to each other through chemical
substances called pheromones. Modeling individual ants- ability to
manipulate this substance can help an ACS find the best solution.
This paper introduces a Dynamic Ant Colony System with threelevel
updates (DACS3) that enhance an existing ACS. Experiments
were conducted to observe single ant behavior in a colony of
Malaysian House Red Ants. Such behavior was incorporated into the
DACS3 algorithm. We benchmark the performance of DACS3 versus
DACS on TSP instances ranging from 14 to 100 cities. The result
shows that the DACS3 algorithm can achieve shorter distance in
most cases and also performs considerably faster than DACS.