Abstract: Breast cancer is the most common malignancy in the
world among women. Many therapies have been designed to treat
this disease. Mamectomy, chemotherapy and radiotherapy are still
the main therapies of breast cancer. However, the results were
unsatisfactory and still far from the ideal treatment.
PM 701is a natural product, has anticancer activity. The bioactive
fraction PMF and subfraction PMFK had been isolated from PM701.
PM 701 and its fractions were proved to have a cytotoxic properties
against different cancer cell lines. This article is directed for the
further examination of lyophilized PM701 and its active fractions on
the growth of breast cancer cells (MCF-7). PM 701, PMF or PMFK
were adding to the cultural medium, where MCF-7 is incubated.
PM 701, PMF or PMFK were able to inhibit significantly the
proliferation of MCF-7 cells, Moreover these new agents were
proved to induce apoptosis of the breast cancer cells; through its
direct effect on the nuclei.
Abstract: This paper deals with a periodic-review substitutable
inventory system for a finite and an infinite number of periods. Here
an upward substitution structure, a substitution of a more costly item
by a less costly one, is assumed, with two products. At the beginning
of each period, a stochastic demand comes for the first item only,
which is quality-wise better and hence costlier. Whenever an arriving
demand finds zero inventory of this product, a fraction of unsatisfied
customers goes for its substitutable second item. An optimal ordering
policy has been derived for each period. The results are illustrated
with numerical examples. A sensitivity analysis has been done to
examine how sensitive the optimal solution and the maximum profit
are to the values of the discount factor, when there is a large number
of periods.
Abstract: In this paper multi-objective genetic algorithms are
employed for Pareto approach optimization of ideal Turboshaft
engines. In the multi-objective optimization a number of conflicting
objective functions are to be optimized simultaneously. The
important objective functions that have been considered for
optimization are specific thrust (F/m& 0), specific fuel consumption
( P S ), output shaft power 0 (& /&) shaft W m and overall efficiency( ) O
η .
These objectives are usually conflicting with each other. The design
variables consist of thermodynamic parameters (compressor pressure
ratio, turbine temperature ratio and Mach number).
At the first stage single objective optimization has been
investigated and the method of NSGA-II has been used for multiobjective
optimization. Optimization procedures are performed for
two and four objective functions and the results are compared for
ideal Turboshaft engine. In order to investigate the optimal
thermodynamic behavior of two objectives, different set, each
including two objectives of output parameters, are considered
individually. For each set Pareto front are depicted. The sets of
selected decision variables based on this Pareto front, will cause the
best possible combination of corresponding objective functions.
There is no superiority for the points on the Pareto front figure,
but they are superior to any other point. In the case of four objective
optimization the results are given in tables.
Abstract: In this paper, we represent protein structure by using
graph. A protein structure database will become a graph database.
Each graph is represented by a spectral vector. We use Jacobi
rotation algorithm to calculate the eigenvalues of the normalized
Laplacian representation of adjacency matrix of graph. To measure
the similarity between two graphs, we calculate the Euclidean
distance between two graph spectral vectors. To cluster the graphs,
we use M-tree with the Euclidean distance to cluster spectral vectors.
Besides, M-tree can be used for graph searching in graph database.
Our proposal method was tested with graph database of 100 graphs
representing 100 protein structures downloaded from Protein Data
Bank (PDB) and we compare the result with the SCOP hierarchical
structure.
Abstract: Amazing development of the information technology,
communications and internet expansion as well as the requirements
of the city managers to new ideas to run the city and higher
participation of the citizens encourage us to complete the electronic
city as soon as possible. The foundations of this electronic city are in
information technology. People-s participation in metropolitan
management is a crucial topic. Information technology does not
impede this matter. It can ameliorate populace-s participation and
better interactions between the citizens and the city managers.
Citizens can proffer their ideas, beliefs and votes through digital
mass media based upon the internet and computerization plexuses on
the topical matters to receive appropriate replies and services. They
can participate in urban projects by becoming cognizant of the city
views. The most significant challenges are as follows: information
and communicative management, altering citizens- views, as well as
legal and office documents
Electronic city obstacles have been identified in this research. The
required data were forgathered through questionnaires to identify the
barriers from a statistical community comprising specialists and
practitioners of the ministry of information technology and
communication, the municipality information technology
organization.
The conclusions demonstrate that the prioritized electronic city
application barriers in Iran are as follows:
The support quandaries (non-financial ones), behavioral, cultural
and educational plights, the security, legal and license predicaments,
the hardware, orismological and infrastructural curbs, the software
and fiscal problems.
Abstract: Growing world population has fundamental impacts
and often catastrophic on natural habitat. The immethodical
consumption of energy, destruction of the forests and extinction of
plant and animal species are the consequence of this experience.
Urban sustainability and sustainable urban development, that is so
spoken these days, should be considered as a strategy, goal and
policy, beyond just considering environmental issues and protection.
The desert-s climate has made a bunch of problems for its residents.
Very hot and dry climate in summers of the Iranian desert areas,
when there was no access to modern energy source and mechanical
cooling systems in the past, made Iranian architects to design a
natural ventilation system in their buildings. The structure, like a
tower going upward the roof, besides its ornamental application and
giving a beautiful view to the building, was used as a spontaneous
ventilation system. In this paper, it has been tried to name the
problems of the area and it-s inconvenience, then some answers has
pointed out in order to solve the problems and as an alternative
solution BADGIR (wind-catcher) has been introduced as a solution
knowing that it has been playing a major role in dealing with the
problems.
Abstract: It is essential to have a uniform and calm flow field
for a settling tank to have high performance. In general, the
recirculation zones always occurred in sedimentation tanks. The
presence of these regions may have different effects. The nonuniformity
of the velocity field, the short-circuiting at the surface and
the motion of the jet at the bed of the tank that occurs because of the
recirculation in the sedimentation layer, are affected by the geometry
of the tank. There are some ways to decrease the size of these dead
zones, which would increase the performance. One of the ways is to
use a suitable baffle configuration. In this study, the presence of
baffle with different position has been investigated by a finite volume
method, with VOF (Volume of Fluid) model. Besides, the k-ε
turbulence model is used in the numerical calculations. The results
indicate that the best position of the baffle is obtained when the
volume of the recirculation region is minimized or is divided to
smaller part and the flow field trend to be uniform in the settling
zone.
Abstract: This paper presents an innovative approach within the area of Group Decision Support System (GDSS) by using tools based on intelligent agents. It introduces iGDSS, a software platform for decision support and collaboration and an application of this platform - eCollaborative Decisions - for academic environment, all these developed within a framework of a research project.
Abstract: This paper deals with new concept of using compressed atmospheric air as a zero pollution power source for running motorbikes. The motorbike is equipped with an air turbine in place of an internal combustion engine, and transforms the energy of the compressed air into shaft work. The mathematical modeling and performance evaluation of a small capacity compressed air driven vaned type novel air turbine is presented in this paper. The effect of isobaric admission and adiabatic expansion of high pressure air for different rotor to casing diameter ratios with respect to different vane angles (number of vanes) have been considered and analyzed. It is found that the shaft work output is optimum for some typical values of rotor / casing diameter ratios at a particular value of vane angle (no. of vanes). In this study, the maximum power is obtained as 4.5kW - 5.3kW (5.5-6.25 HP) when casing diameter is taken 100 mm, and rotor to casing diameter ratios are kept from 0.65 to 0.55. This value of output is sufficient to run motorbike.
Abstract: This is a cross-cultural study that determines South
African multinational enterprises (MNEs) entry strategies as they
invest in Africa. An integrated theoretical framework comprising the
transaction cost theory, Uppsala model, eclectic paradigm and the
distance framework was adopted. A sample of 40 South African
MNEs with 415 existing FDI entries in Africa was drawn. Using an
ordered logistic regression model, the impact of culture on the choice
of degree of control by South African MNEs in Africa was
determined. Cultural distance was one of significant factors that
influenced South African MNEs- choice of degree of control.
Furthermore, South African MNEs are risk averse in all countries in
Africa but minimize the risks differently across sectors. Service
sectors chooses to own their subsidiaries 100% and avoid dealing
with the locals while manufacturing, resources and construction
choose to have a local partner to share the risk.
Abstract: This paper presented two new efficient algorithms
for contour approximation. The proposed algorithm is compared
with Ramer (good quality), Triangle (faster) and Trapezoid (fastest)
in this work; which are briefly described. Cartesian co-ordinates of
an input contour are processed in such a manner that finally
contours is presented by a set of selected vertices of the edge of the
contour. In the paper the main idea of the analyzed procedures for
contour compression is performed. For comparison, the mean
square error and signal-to-noise ratio criterions are used.
Computational time of analyzed methods is estimated depending on
a number of numerical operations. Experimental results are
obtained both in terms of image quality, compression ratios, and
speed. The main advantages of the analyzed algorithm is small
numbers of the arithmetic operations compared to the existing
algorithms.
Abstract: Information Technology (IT) projects are always
accompanied by various risks and because of high rate of failure in
such projects, managing risks in order to neutralize or at least
decrease their effects on the success of the project is strongly
essential. In this paper, fuzzy analytical hierarchy process (FAHP) is
exploited as a means of risk evaluation methodology to prioritize and
organize risk factors faced in IT projects. A real case of IT projects, a
project of design and implementation of an integrated information
system in a vehicle producing company in Iran is studied. Related
risk factors are identified and then expert qualitative judgments about
these factors are acquired. Translating these judgments to fuzzy
numbers and using them as an input to FAHP, risk factors are then
ranked and prioritized by FAHP in order to make project managers
aware of more important risks and enable them to adopt suitable
measures to deal with these highly devastative risks.
Abstract: Reference point effects of top managers exerts an influence on managerial decision-making behaviors. We introduces the main idea of developing the decision behavior testing system designed for top manager in team task circumstance. According to the theory of the reference point effect, study of testing experiments in the reference point effect is carried out. Under managerial decision-making simulation environment, a platform is designed for testing reference point effect. The system uses the outcome of the value of the reference point to report the characteristics of the decision behavior of top managers.
Abstract: The submitted paper deals with the problems of
trapping and enriching the gases and aerosols of the substances to be
determined in the ambient atmosphere. Further, the paper is focused
on the working principle of the miniaturized portable continuous
concentrator we have designed and the possibilities of its
application in air sampling and accumulation of organic and
inorganic substances with which the air is contaminated. The stress is
laid on trapping vapours and aerosols of solid substances with the
comparatively low vapour tension such as explosive compounds.
Abstract: Amarindra-vinitchai-mahaisuraya Bhiman throne hall
is one of the most significant throne halls in the grand palace in the
Ratthanakosin city situated in Bangkok, Thailand. This is the first
group of throne halls built in order to serve as a place for meetings,
performing state affairs and royal duties until the present time. The
structure and pattern of architectural design including the decoration
and interior design of the throne hall obviously exhibits and convey
the status of the king under the context of Thai society in the early
period of Ratthanakosin era. According to the tradition of ruling the
kingdom in absolute monarchy which had been in place since
Ayutthaya era (A.D.1350-1767), the king was deemed as Deva Raja,
the highest power and authority over the kingdom and as the greatest
emperor of the universe (Chakkravatin). The architectural design
adopted the concept of “Prasada" or Viman which served as the
dwelling place of the gods and was presented in the form of “Thai
traditional architecture" For the interior design of the throne hall, it
had been adopted to be the heaven and the centre of the Universe in
line with the cosmological beliefs of ancient people described in
scripture Tribhumikatha (Tri Bhumi) written by Phra Maha Thamma
Raja (Phraya Lithai) of the Sukhothai era (A.D.1347-1368).
According to this belief, the throne hall had been designed to represent
mount Meru, the central of the universe. On the top end of Mount
Meru is situated the Viman and dwelling place of Indra who is the king
of gods according to the idea of Deva Raja (the king god Avatar). At
the same time, Indra also existed as the king of the universe
simultaneously.
Abstract: The paper presented a transient population dynamics of phase singularities in 2D Beeler-Reuter model. Two stochastic modelings are examined: (i) the Master equation approach with the transition rate (i.e., λ(n, t) = λ(t)n and μ(n, t) = μ(t)n) and (ii) the nonlinear Langevin equation approach with a multiplicative noise. The exact general solution of the Master equation with arbitrary time-dependent transition rate is given. Then, the exact solution of the mean field equation for the nonlinear Langevin equation is also given. It is demonstrated that transient population dynamics is successfully identified by the generalized Logistic equation with fractional higher order nonlinear term. It is also demonstrated the necessity of introducing time-dependent transition rate in the master equation approach to incorporate the effect of nonlinearity.
Abstract: This paper proposes an innovative methodology for
Acceptance Sampling by Variables, which is a particular category of
Statistical Quality Control dealing with the assurance of products
quality. Our contribution lies in the exploitation of machine learning
techniques to address the complexity and remedy the drawbacks of
existing approaches. More specifically, the proposed methodology
exploits Artificial Neural Networks (ANNs) to aid decision making
about the acceptance or rejection of an inspected sample. For any
type of inspection, ANNs are trained by data from corresponding
tables of a standard-s sampling plan schemes. Once trained, ANNs
can give closed-form solutions for any acceptance quality level and
sample size, thus leading to an automation of the reading of the
sampling plan tables, without any need of compromise with the
values of the specific standard chosen each time. The proposed
methodology provides enough flexibility to quality control engineers
during the inspection of their samples, allowing the consideration of
specific needs, while it also reduces the time and the cost required for
these inspections. Its applicability and advantages are demonstrated
through two numerical examples.
Abstract: The article deals with pneumatic and hot wire
anemometry measurement on subsonic axi-symmetric air ejector.
Performances of the ejector with and without pulsations of primary
flow are compared, measuring of characteristic pressures and mass
flow rates are performed and ejector efficiency is evaluated. The
pulsations of primary flow are produced by a synthetic jet generator,
which is placed in the supply line of the primary flow just in front of
the primary nozzle. The aim of the pulsation is to intensify the
mixing process. In the article we present: Pressure measuring of
pulsation on the mixing chamber wall, behind the mixing chamber
and behind the diffuser measured by fast pressure transducers and
results of hot wire anemometry measurement. It was found out that
using of primary flow pulsations yields higher back pressure behind
the ejector and higher efficiency. The processes in this ejector and
influences of primary flow pulsations on the mixing processes are
described.
Abstract: This paper investigates the optimization problem of
multi-product aggregate production planning (APP) with fuzzy data.
From a comprehensive viewpoint of conserving the fuzziness of input
information, this paper proposes a method that can completely
describe the membership function of the performance measure. The
idea is based on the well-known Zadeh-s extension principle which
plays an important role in fuzzy theory. In the proposed solution
procedure, a pair of mathematical programs parameterized by
possibility level a is formulated to calculate the bounds of the
optimal performance measure at a . Then the membership function of
the optimal performance measure is constructed by enumerating
different values of a . Solutions obtained from the proposed method
contain more information, and can offer more chance to achieve the
feasible disaggregate plan. This is helpful to the decision-maker in
practical applications.
Abstract: This paper deals with the thermo-mechanical deformation behavior of shear deformable functionally graded ceramicmetal (FGM) plates. Theoretical formulations are based on higher order shear deformation theory with a considerable amendment in the transverse displacement using finite element method (FEM). The mechanical properties of the plate are assumed to be temperaturedependent and graded in the thickness direction according to a powerlaw distribution in terms of the volume fractions of the constituents. The temperature field is supposed to be a uniform distribution over the plate surface (XY plane) and varied in the thickness direction only. The fundamental equations for the FGM plates are obtained using variational approach by considering traction free boundary conditions on the top and bottom faces of the plate. A C0 continuous isoparametric Lagrangian finite element with thirteen degrees of freedom per node have been employed to accomplish the results. Convergence and comparison studies have been performed to demonstrate the efficiency of the present model. The numerical results are obtained for different thickness ratios, aspect ratios, volume fraction index and temperature rise with different loading and boundary conditions. Numerical results for the FGM plates are provided in dimensionless tabular and graphical forms. The results proclaim that the temperature field and the gradient in the material properties have significant role on the thermo-mechanical deformation behavior of the FGM plates.