Abstract: The optimal extraction condition of dried
Echinocactus grusonii powder was studied. The three independent
variables are raw material drying temperature, extraction
temperature, and extraction time. The dependent variables are both
yield percentage of crude extract and total phenolic quantification as
gallic acid equivalent in crude extract. The experimental design was
based on central composite design. Highest yield percentage of crude
extract could get from extraction condition at raw material drying
temperature at 60°C, extraction temperature at 15°C, and extraction
time for 25 min °C. Moreover, the crude extract with highest phenolic
occurred by extraction condition of raw material drying temperature
at 60°C, extraction temperature at 35 °C, and extraction lasting 25
min.
Abstract: Mammalian genomes contain large number of
retroelements (SINEs, LINEs and LTRs) which could affect
expression of protein coding genes through associated transcription
factor binding sites (TFBS). Activity of the retroelement-associated
TFBS in many genes is confirmed experimentally but their global
functional impact remains unclear. Human SINEs (Alu repeats) and
mouse SINEs (B1 and B2 repeats) are known to be clustered in GCrich
gene rich genome segments consistent with the view that they
can contribute to regulation of gene expression. We have shown
earlier that Alu are involved in formation of cis-regulatory modules
(clusters of TFBS) in human promoters, and other authors reported
that Alu located near promoter CpG islands have an increased
frequency of CpG dinucleotides suggesting that these Alu are
undermethylated. Human Alu and mouse B1/B2 elements have an
internal bipartite promoter for RNA polymerase III containing
conserved sequence motif called B-box which can bind basal
transcription complex TFIIIC. It has been recently shown that TFIIIC
binding to B-box leads to formation of a boundary which limits
spread of repressive chromatin modifications in S. pombe. SINEassociated
B-boxes may have similar function but conservation of
TFIIIC binding sites in SINEs located near mammalian promoters
has not been studied earlier. Here we analysed abundance and
distribution of retroelements (SINEs, LINEs and LTRs) in annotated
sequences of the Database of mammalian transcription start sites
(DBTSS). Fractions of SINEs in human and mouse promoters are
slightly lower than in all genome but >40% of human and mouse
promoters contain Alu or B1/B2 elements within -1000 to +200 bp
interval relative to transcription start site (TSS). Most of these SINEs
is associated with distal segments of promoters (-1000 to -200 bp
relative to TSS) indicating that their insertion at distances >200 bp
upstream of TSS is tolerated during evolution. Distribution of SINEs
in promoters correlates negatively with the distribution of CpG
sequences. Using analysis of abundance of 12-mer motifs from the
B1 and Alu consensus sequences in genome and DBTSS it has been
confirmed that some subsegments of Alu and B1 elements are poorly
conserved which depends in part on the presence of CpG
dinucleotides. One of these CpG-containing subsegments in B1
elements overlaps with SINE-associated B-box and it shows better
conservation in DBTSS compared to genomic sequences. It has been
also studied conservation in DBTSS and genome of the B-box
containing segments of old (AluJ, AluS) and young (AluY) Alu
repeats and found that CpG sequence of the B-box of old Alu is
better conserved in DBTSS than in genome. This indicates that Bbox-
associated CpGs in promoters are better protected from
methylation and mutation than B-box-associated CpGs in genomic
SINEs. These results are consistent with the view that potential
TFIIIC binding motifs in SINEs associated with human and mouse
promoters may be functionally important. These motifs may protect
promoters from repressive histone modifications which spread from
adjacent sequences. This can potentially explain well known
clustering of SINEs in GC-rich gene rich genome compartments and
existence of unmethylated CpG islands.
Abstract: Realistic systems generally are systems with various
inputs and outputs also known as Multiple Input Multiple Output
(MIMO). Such systems usually prove to be complex and difficult to
model and control purposes. Therefore, decomposition was used to
separate individual inputs and outputs. A PID is assigned to each
individual pair to regulate desired settling time. Suitable parameters
of PIDs obtained from Genetic Algorithm (GA), using Mean of
Squared Error (MSE) objective function.
Abstract: Ants are fascinating creatures that demonstrate the
ability to find food and bring it back to their nest. Their ability as a
colony, to find paths to food sources has inspired the development of
algorithms known as Ant Colony Systems (ACS). The principle of
cooperation forms the backbone of such algorithms, commonly used
to find solutions to problems such as the Traveling Salesman
Problem (TSP). Ants communicate to each other through chemical
substances called pheromones. Modeling individual ants- ability to
manipulate this substance can help an ACS find the best solution.
This paper introduces a Dynamic Ant Colony System with threelevel
updates (DACS3) that enhance an existing ACS. Experiments
were conducted to observe single ant behavior in a colony of
Malaysian House Red Ants. Such behavior was incorporated into the
DACS3 algorithm. We benchmark the performance of DACS3 versus
DACS on TSP instances ranging from 14 to 100 cities. The result
shows that the DACS3 algorithm can achieve shorter distance in
most cases and also performs considerably faster than DACS.
Abstract: Autism Spectrum Disorders (ASDs) are characterized
by abnormalities in social interaction and communication, as well as
repetitive and stereotyped behaviors. Although various studies have
been conducted in ASDs etiology across the world, it seems that they
are still unknown in Middle East. Some scientific researches have
been conducted on ASDs in Middle East (ME) especially in
Kingdom of Saudi Arabia (KSA).
A systematic literature review was performed to identify the ASDs
studies in KSA. Accordingly, PubMed, ISI web of Science and
Google were searched to find KSA and ME studies in ASDs. The
main focus of this review work is to outline an improved
understanding of the underpinnings of ASD in order to achieve
therapeutic interventions and we will discuss the main problem we
waiting for solution with reference with role of Transcranial
Magnetic Stimulation (TMS) to modulate cortical activity improve
understanding ASD.
Abstract: Celiac disease is an immune-mediated disease, triggered in genetically susceptible individuals by ingested gluten from wheat, rye, barley and other closely related cereal grains. The only effective treatment is a strict gluten free diet for life. Latvian producers do not offer gluten-free products. In this research, use of extruded maize flour was tested for substituting rice, maize or buckwheat flour in gluten-free bread formulations at different ratios. Also the influence of extruded maize flour on the quality parameters of gluten-free bread was investigated. The aim of research was to study the influence of extruded maize flour on gluten-free bread quality. Addition of extruded maize flour affect gluten-free bread crumb color, structure of crumb, weight loss and dry off of bread.
Abstract: This paper considers the design of a motion planner
that will simultaneously accomplish control and motion planning of a
n-link nonholonomic mobile manipulator, wherein, a n-link
holonomic manipulator is coupled with a nonholonomic mobile
platform, within an obstacle-ridden environment. This planner,
derived from the Lyapunov-based control scheme, generates
collision-free trajectories from an initial configuration to a final
configuration in a constrained environment cluttered with stationary
solid objects of different shapes and sizes. We demonstrate the
efficiency of the control scheme and the resulting acceleration
controllers of the mobile manipulator with results through computer
simulations of an interesting scenario.
Abstract: At present, dictionary attack has been the basic tool for
recovering key passwords. In order to avoid dictionary attack, users
purposely choose another character strings as passwords. According to
statistics, about 14% of users choose keys on a keyboard (Kkey, for
short) as passwords. This paper develops a framework system to attack
the password chosen from Kkeys and analyzes its efficiency. Within
this system, we build up keyboard rules using the adjacent and parallel
relationship among Kkeys and then use these Kkey rules to generate
password databases by depth-first search method. According to the
experiment results, we find the key space of databases derived from
these Kkey rules that could be far smaller than the password databases
generated within brute-force attack, thus effectively narrowing down
the scope of attack research. Taking one general Kkey rule, the
combinations in all printable characters (94 types) with Kkey adjacent
and parallel relationship, as an example, the derived key space is about
240 smaller than those in brute-force attack. In addition, we
demonstrate the method's practicality and value by successfully
cracking the access password to UNIX and PC using the password
databases created
Abstract: This paper addresses the fundamental requirements for
starting an online business. It covers the process of ideation,
conceptualization, formulation, and implementation of new venture
ideas on the Web. Using Facebook as an illustrative example, we learn
how to turn an idea into a successful electronic business and to execute
a business plan with IT skills, management expertise, a good
entrepreneurial attitude, and an understanding of Internet culture. The
personality traits and characteristics of a successful e-commerce
entrepreneur are discussed with reference to Facebook-s founder,
Mark Zuckerberg. Facebook is a social and e-commerce success. It
provides a trusted environment of which participants can conduct
business with social experience. People are able to discuss products
before, during the after the sale within the Facebook environment. The
paper also highlights the challenges and opportunities for e-commerce
entrepreneurial startups to go public and of entering the China market.
Abstract: The development of the power electronics has allowed
increasing the precision and reliability of the electrical trainings,
thanks to the adjustable inverters, as the Pulse Wide Modulation
(PWM) five level inverters, which is the object of study in this
article.The authors treat the relation between the law order adopted for
a given system and the oscillations of the electrical and mechanical
parameters of which the tolerance depends on the process with which
they are integrated (paper factory, lifting of the heavy loads,
etc.).Thus the best choice of the regulation indexes allows us to
achieve stability and safety training without investment (management
of existing equipment).
Abstract: The story of Alibaba demonstrates a credible example of how a small start-up company can eventually make it big in the global economy through the Internet. This case study does not attempt to present Alibaba as a perfect formula; rather, it discusses the strategies carried out by the firm and, in the process, culls out the important lessons that can guide start-ups and aspiring entrepreneurs in the complex world of online trading. Similar to the interesting and exotic Asian cuisine that continuously evolves from the diversity of Asia-s people and their unique culture and personality, Alibaba has successfully transformed itself over the years, adapting to the changes in and demands of online businessto- business (B2B) commerce.
Abstract: This study was initiated with a three prong objective.
One, to identify the relationship between Technological
Competencies factors (Technical Capability, Firm Innovativeness
and E-Business Practices and professional service firms- business
performance. To investigate the predictors of professional service
firms business performance and finally to evaluate the predictors of
business performance according to the type of professional service
firms, a survey questionnaire was deployed to collect empirical data.
The questionnaire was distributed to the owners of the professional
small medium size enterprises services in the Accounting, Legal,
Engineering and Architecture sectors. Analysis showed that all three
Technology Competency factors have moderate effect on business
performance. In addition, the regression models indicate that
technical capability is the most highly influential that could
determine business performance, followed by e-business practices
and firm innovativeness. Subsequently, the main predictor of
business performance for all types of firms is Technical capability.
Abstract: Feature selection plays an important role in applications with high dimensional data. The assessment of the stability of feature selection/ranking algorithms becomes an important issue when the dataset is small and the aim is to gain insight into the underlying process by analyzing the most relevant features. In this work, we propose a graphical approach that enables to analyze the similarity between feature ranking techniques as well as their individual stability. Moreover, it works with whatever stability metric (Canberra distance, Spearman's rank correlation coefficient, Kuncheva's stability index,...). We illustrate this visualization technique evaluating the stability of several feature selection techniques on a spectral binary dataset. Experimental results with a neural-based classifier show that stability and ranking quality may not be linked together and both issues have to be studied jointly in order to offer answers to the domain experts.
Abstract: This paper describes Nano-particle based Planar Laser
Scattering (NPLS) flow visualization of angled supersonic jets into a
supersonic cross flow based on the HYpersonic Low TEmperature
(HYLTE) nozzle which was widely used in DF chemical laser. In
order to investigate the non-reacting flowfield in the HYLTE nozzle, a
testing section with windows was designed and manufactured. The
impact of secondary fluids orifice separation on mixing was examined.
For narrow separation of orifices, the secondary fuel penetration
increased obviously compared to diluent injection, which means
smaller separation of diluent and fuel orifices would enhance the
mixing of fuel and oxidant. Secondary injections with angles of 30, 40
and 50 degrees were studied. It was found that the injectant
penetration increased as the injection angle increased, while the
interfacial surface area to entrain the freestream fluid is largest when
the injection angle is 40 degree.
Abstract: Chatter vibration has been a troublesome problem
for a machine tool toward the high precision and high speed machining.
Essentially, the machining performance is determined by the dynamic
characteristics of the machine tool structure and dynamics of cutting
process, which can further be identified in terms of the stability lobe
diagram. Therefore, realization on the machine tool dynamic behavior
can help to enhance the cutting stability. To assess the dynamic
characteristics and machining stability of a vertical milling system
under the influence of a linear guide, this study developed a finite
element model integrated the modeling of linear components with the
implementation of contact stiffness at the rolling interface. Both the
finite element simulations and experimental measurements reveal that
the linear guide with different preload greatly affects the vibration
behavior and milling stability of the vertical column spindle head
system, which also clearly indicate that the predictions of the
machining stability agree well with the cutting tests. It is believed that
the proposed model can be successfully applied to evaluate the
dynamics performance of machine tool systems of various
configurations.
Abstract: This paper provides new ways to explore the old
problem of failure of information systems development in an
organisation. Based on the theory of cognitive dissonance,
information systems (IS) failure is defined as a gap between what the
users expect from an information system and how well these
expectations are met by the perceived performance of the delivered
system. Bridging the expectation-perception gap requires that IS
professionals make a radical change from being the proprietor of
information systems and products to being service providers. In order
to deliver systems and services that IS users perceive as valuable, IS
people must become expert in determining and assessing users-
expectations and perceptions. It is also suggested that the IS
community, in general, has given relatively little attention to the
front-end process of requirements specification for IS development.
There is a simplistic belief that requirements are obtainable from
users, they are then translatable into a formal specification. The
process of information needs analysis is problematic and worthy of
investigation.
Abstract: Today automobile and aerospace industries realise Laser Beam Welding for a clean and non contact source of heating and fusion for joining of sheets. The welding performance is mainly based on by the laser welding parameters. Some concepts related to Artificial Neural Networks and how can be applied to model weld bead geometry and mechanical properties in terms of equipment parameters are reported in order to evaluate the accuracy and compare it with traditional modeling schemes. This review reveals the output features of Titanium and Aluminium weld bead geometry and mechanical properties such as ultimate tensile strength, yield strength, elongation and reduction of the area of the weld using Artificial Neural Network.
Abstract: This paper investigates the problem of tracking spa¬tiotemporal changes of a satellite image through the use of Knowledge Discovery in Database (KDD). The purpose of this study is to help a given user effectively discover interesting knowledge and then build prediction and decision models. Unfortunately, the KDD process for spatiotemporal data is always marked by several types of imperfections. In our paper, we take these imperfections into consideration in order to provide more accurate decisions. To achieve this objective, different KDD methods are used to discover knowledge in satellite image databases. Each method presents a different point of view of spatiotemporal evolution of a query model (which represents an extracted object from a satellite image). In order to combine these methods, we use the evidence fusion theory which considerably improves the spatiotemporal knowledge discovery process and increases our belief in the spatiotemporal model change. Experimental results of satellite images representing the region of Auckland in New Zealand depict the improvement in the overall change detection as compared to using classical methods.
Abstract: It has been shown that in most accidents the driver is responsible due to being distracted or misjudging the situation. In order to solve such problems research has been dedicated to developing driver assistance systems that are able to monitor the traffic situation around the vehicle. This paper presents methods for recognizing several circumstances on a road. The methods use both the in-vehicle warning systems and the roadside infrastructure. Preliminary evaluation results for fog and ice-on-road detection are presented. The ice detection results are based on data recorded in a test track dedicated to tyre friction testing. The achieved results anticipate that ice detection could work at a performance of 70% detection with the right setup, which is a good foundation for implementation. However, the full benefit of the presented cooperative system is achieved by fusing the outputs of multiple data sources, which is the key point of discussion behind this publication.
Abstract: In H.264/AVC video encoding, rate-distortion
optimization for mode selection plays a significant role to achieve
outstanding performance in compression efficiency and video quality.
However, this mode selection process also makes the encoding
process extremely complex, especially in the computation of the ratedistortion
cost function, which includes the computations of the sum
of squared difference (SSD) between the original and reconstructed
image blocks and context-based entropy coding of the block. In this
paper, a transform-domain rate-distortion optimization accelerator
based on fast SSD (FSSD) and VLC-based rate estimation algorithm
is proposed. This algorithm could significantly simplify the hardware
architecture for the rate-distortion cost computation with only
ignorable performance degradation. An efficient hardware structure
for implementing the proposed transform-domain rate-distortion
optimization accelerator is also proposed. Simulation results
demonstrated that the proposed algorithm reduces about 47% of total
encoding time with negligible degradation of coding performance.
The proposed method can be easily applied to many mobile video
application areas such as a digital camera and a DMB (Digital
Multimedia Broadcasting) phone.