Abstract: This paper proposes a rotational invariant texture
feature based on the roughness property of the image for psoriasis
image analysis. In this work, we have applied this feature for image
classification and segmentation. The fuzzy concept is employed to
overcome the imprecision of roughness. Since the psoriasis lesion is
modeled by a rough surface, the feature is extended for calculating
the Psoriasis Area Severity Index value. For classification and
segmentation, the Nearest Neighbor algorithm is applied. We have
obtained promising results for identifying affected lesions by using
the roughness index and severity level estimation.
Abstract: Psoriasis is a chronic inflammatory skin condition
which affects 2-3% of population around the world. Psoriasis Area
and Severity Index (PASI) is a gold standard to assess psoriasis
severity as well as the treatment efficacy. Although a gold standard,
PASI is rarely used because it is tedious and complex. In practice,
PASI score is determined subjectively by dermatologists, therefore
inter and intra variations of assessment are possible to happen even
among expert dermatologists. This research develops an algorithm to
assess psoriasis lesion for PASI scoring objectively. Focus of this
research is thickness assessment as one of PASI four parameters
beside area, erythema and scaliness. Psoriasis lesion thickness is
measured by averaging the total elevation from lesion base to lesion
surface. Thickness values of 122 3D images taken from 39 patients
are grouped into 4 PASI thickness score using K-means clustering.
Validation on lesion base construction is performed using twelve
body curvature models and show good result with coefficient of
determinant (R2) is equal to 1.
Abstract: The process of laser absorption in the skin during
laser irradiation was a critical point in medical application
treatments. Delivery the correct amount of laser light is a critical
element in photodynamic therapy (PDT). More amounts of laser
light able to affect tissues in the skin and small amount not able to
enhance PDT procedure in skin. The knowledge of the skin tone
laser dependent distribution of 635 nm radiation and its penetration
depth in skin is a very important precondition for the investigation of
advantage laser induced effect in (PDT) in epidermis diseases
(psoriasis). The aim of this work was to estimate an optimum effect
of diode laser (635 nm) on the treatment of epidermis diseases in
different color skin. Furthermore, it is to improve safety of laser in
PDT in epidermis diseases treatment. Advanced system analytical
program (ASAP) which is a new approach in investigating the PDT,
dependent on optical properties of different skin color was used in
present work. A two layered Realistic Skin Model (RSM); stratum
corneum and epidermal with red laser (635 nm, 10 mW) were used
for irradiative transfer to study fluence and absorbance in different
penetration for various human skin colors. Several skin tones very
fair, fair, light, medium and dark are used to irradiative transfer. This
investigation involved the principles of laser tissue interaction when
the skin optically injected by a red laser diode. The results
demonstrated that the power characteristic of a laser diode (635 nm)
can affect the treatment of epidermal disease in various color skins.
Power absorption of the various human skins were recorded and
analyzed in order to find the influence of the melanin in PDT
treatment in epidermal disease. A two layered RSM show that the
change in penetration depth in epidermal layer of the color skin has a
larger effect on the distribution of absorbed laser in the skin; this is
due to the variation of the melanin concentration for each color.
Abstract: Psoriasis is a widespread skin disease affecting up to 2% population with plaque psoriasis accounting to about 80%. It can be identified as a red lesion and for the higher severity the lesion is usually covered with rough scale. Psoriasis Area Severity Index (PASI) scoring is the gold standard method for measuring psoriasis severity. Scaliness is one of PASI parameter that needs to be quantified in PASI scoring. Surface roughness of lesion can be used as a scaliness feature, since existing scale on lesion surface makes the lesion rougher. The dermatologist usually assesses the severity through their tactile sense, therefore direct contact between doctor and patient is required. The problem is the doctor may not assess the lesion objectively. In this paper, a digital image analysis technique is developed to objectively determine the scaliness of the psoriasis lesion and provide the PASI scaliness score. Psoriasis lesion is modelled by a rough surface. The rough surface is created by superimposing a smooth average (curve) surface with a triangular waveform. For roughness determination, a polynomial surface fitting is used to estimate average surface followed by a subtraction between rough and average surface to give elevation surface (surface deviations). Roughness index is calculated by using average roughness equation to the height map matrix. The roughness algorithm has been tested to 444 lesion models. From roughness validation result, only 6 models can not be accepted (percentage error is greater than 10%). These errors occur due the scanned image quality. Roughness algorithm is validated for roughness measurement on abrasive papers at flat surface. The Pearson-s correlation coefficient of grade value (G) of abrasive paper and Ra is -0.9488, its shows there is a strong relation between G and Ra. The algorithm needs to be improved by surface filtering, especially to overcome a problem with noisy data.