Abstract: The methanolic extracts from seeds of tamarind
(Tamarindus indica) was prepared by Soxhlet apparatus extraction
and evaluated for total phenolic content by Folin-Ciocalteu method.
Then, methanolic extract was screened biological activities (In vitro)
for anti-melanogenic activity by tyrosinase inhibition test, antiinflammation
activity by cyclooxygenase 1 (COX-1) and
cyclooxygenase 2 (COX-2) inhibition test, and cytotoxic screening
test with Vero cells. The results showed that total phenolic content,
which contained in extract, was contained 27.72 mg of gallic acid
equivalent per g of dry weight. The ability to inhibit tyrosinase
enzyme, which exerted by Tamarind seed extracts (1 mg/ml) was
52.13 ± 0.42 %. The extract was not possessed inhibitory effect to
COX-1 and COX-2 enzymes and cytotoxic effect to Vero cells. The
finding is concludes that tested seed extract was possessed
antimelanogenic activity with non-toxic effects. However, there was
not exhibited anti-inflammatory activity. Further studies include the
use of advance biological models to confirm this biological activity,
as well as, the isolation and characterization of the purified
compounds that it was contained.
Abstract: The new idea of this research is application of a new fault detection and isolation (FDI) technique for supervision of sensor networks in transportation system. In measurement systems, it is necessary to detect all types of faults and failures, based on predefined algorithm. Last improvements in artificial neural network studies (ANN) led to using them for some FDI purposes. In this paper, application of new probabilistic neural network features for data approximation and data classification are considered for plausibility check in temperature measurement. For this purpose, two-phase FDI mechanism was considered for residual generation and evaluation.
Abstract: Emerging Bio-engineering fields such as Brain
Computer Interfaces, neuroprothesis devices and modeling and
simulation of neural networks have led to increased research activity
in algorithms for the detection, isolation and classification of Action
Potentials (AP) from noisy data trains. Current techniques in the field
of 'unsupervised no-prior knowledge' biosignal processing include
energy operators, wavelet detection and adaptive thresholding. These
tend to bias towards larger AP waveforms, AP may be missed due to
deviations in spike shape and frequency and correlated noise
spectrums can cause false detection. Also, such algorithms tend to
suffer from large computational expense.
A new signal detection technique based upon the ideas of phasespace
diagrams and trajectories is proposed based upon the use of a
delayed copy of the AP to highlight discontinuities relative to
background noise. This idea has been used to create algorithms that
are computationally inexpensive and address the above problems.
Distinct AP have been picked out and manually classified from
real physiological data recorded from a cockroach. To facilitate
testing of the new technique, an Auto Regressive Moving Average
(ARMA) noise model has been constructed bases upon background
noise of the recordings. Along with the AP classification means this
model enables generation of realistic neuronal data sets at arbitrary
signal to noise ratio (SNR).
Abstract: A 2.4GHz (RF) down conversion Gilbert Cell mixer,
implemented in a 0.18-μm CMOS technology with a 1.8V supply, is
presented. Current bleeding (charge injection) technique has been
used to increase the conversion gain and the linearity of the mixer.
The proposed mixer provides 10.75 dB conversion gain ( C G ) with
14.3mw total power consumption. The IIP3 and 1-dB compression
point of the mixer are 8dbm and -4.6dbm respectively, at 300 MHz
IF frequencies. Comparing the current design against the
conventional mixer design, demonstrates better performance in the
conversion gain, linearity, noise figure and port-to-port isolation.
Abstract: Modern manufacturing facilities are large scale,
highly complex, and operate with large number of variables under
closed loop control. Early and accurate fault detection and diagnosis
for these plants can minimise down time, increase the safety of plant
operations, and reduce manufacturing costs. Fault detection and
isolation is more complex particularly in the case of the faulty analog
control systems. Analog control systems are not equipped with
monitoring function where the process parameters are continually
visualised. In this situation, It is very difficult to find the relationship
between the fault importance and its consequences on the product
failure. We consider in this paper an approach to fault detection and
analysis of its effect on the production quality using an adaptive
centring and scaling in the pickling process in cold rolling. The fault
appeared on one of the power unit driving a rotary machine, this
machine can not track a reference speed given by another machine.
The length of metal loop is then in continuous oscillation, this affects
the product quality. Using a computerised data acquisition system,
the main machine parameters have been monitored. The fault has
been detected and isolated on basis of analysis of monitored data.
Normal and faulty situation have been obtained by an artificial neural
network (ANN) model which is implemented to simulate the normal
and faulty status of rotary machine. Correlation between the product
quality defined by an index and the residual is used to quality
classification.
Abstract: Analytical seismic response of multi-story building
supported on base isolation system is investigated under real
earthquake motion. The superstructure is idealized as a shear type
flexible building with lateral degree-of-freedom at each floor. The
force-deformation behaviour of the isolation system is modelled by
the bi-linear behaviour which can be effectively used to model all
isolation systems in practice. The governing equations of motion of
the isolated structural system are derived. The response of the system
is obtained numerically by step-by-method under three real recorded
earthquake motions and pulse motions associated in the near-fault
earthquake motion. The variation of the top floor acceleration, interstory
drift, base shear and bearing displacement of the isolated
building is studied under different initial stiffness of the bi-linear
isolation system. It was observed that the high initial stiffness of the
isolation system excites higher modes in base-isolated structure and
generate floor accelerations and story drift. Such behaviour of the
base-isolated building especially supported on sliding type of
isolation systems can be detrimental to sensitive equipment installed
in the building. On the other hand, the bearing displacement and base
shear found to reduce marginally with the increase of the initial
stiffness of the initial stiffness of the isolation system. Further, the
above behaviour of the base-isolated building was observed for
different parameters of the bearing (i.e. post-yield stiffness and
characteristic strength) and earthquake motions (i.e. real time history
as well as pulse type motion).
Abstract: In order to upgrade the seismic resistibility of structures and enhance the functionality of an isolator, a new base isolator called the multiple trench friction pendulum system (MTFPS) is proposed in this study. The proposed MTFPS isolator is composed of a trench concave surface and several intermediate sliding plates in two orthogonal directions. Mathematical formulations have been derived to examine the characteristics of the proposed MTFPS isolator possessing multiple intermediate sliding plates. By means of mathematical formulations, it can be inferred that the natural period and damping effect of the MTFPS isolator with several intermediate sliding plates can be altered continually and controllably during earthquakes. Furthermore, results obtained from shaking table tests demonstrate that the proposed isolator provides good protection to structures for prevention of damage from strong earthquakes.
Abstract: A seismic isolation pad produced by utilizing the scrap
tire rubber which contains interleaved steel reinforcing cords has been
proposed. The steel cords are expected to function similar to the steel
plates used in conventional laminated rubber bearings. The scrap tire
rubber pad (STRP) isolator is intended to be used in low rise
residential buildings of highly seismic areas of the developing
countries. Experimental investigation was conducted on unbonded
STRP isolators, and test results provided useful information including
stiffness, damping values and an eventual instability of the isolation
unit. Finite element analysis (FE analysis) of STRP isolator was
carried out on properly bonded samples. These types of isolators
provide positive incremental force resisting capacity up to shear strain
level of 155%. This paper briefly discusses the force deformation
behavior of bonded STRP isolators including stability of the isolation
unit.
Abstract: Composting is the process in which municipal solid
waste (MSW) and other organic waste materials such as biosolids
and manures are decomposed through the action of bacteria and other
microorganisms into a stable granular material which, applied to
land, as soil conditioner. Microorganisms, especially those that are
able to degrade polymeric organic material have a key role in speed
up this process. The aim of this study has been established to
isolation of microorganisms with high ability to production
extracellular enzymes for degradation of natural polymers that are
exists in MSW for decreasing time of degradation phase. Our
experimental study for isolation designed in two phases: in first
phase we isolated degrading microorganism with selected media that
consist a special natural polymer such as cellulose, starch, lipids and
etc as sole source of carbon. In second phase we selected
microorganism that had high degrading enzyme production with
enzymatic assay for seed production. However, our findings in pilot
scale have indicated that usage of this microbial consortium had high
efficiency for decreasing degradation phase.
Abstract: If science is supposed to gain greater social
relevance and acceptance, researchers must not only relate to
the broader public, but also promote intercourse within the
ivory tower itself. The latter process has been under way
successfully for a number of years in the form of
transdisciplinary research initiatives. What is still lacking is a
broad debate about the necessity to look around properly and
face up to opposing views on one and the same topic within
our own discipline.
Abstract: MMR vaccine failure had been reported globally and
here we report that it occurs now in India. Samples were collected from clinically suspected mumps cases were subjected for anti
mumps antibodies, virus isolation, RT-PCR, sequencing and
phylogenetic tree analysis. 56 samples collected from men and women belonging to various age groups. 30 had been vaccinated and
the status of 26 patients was unknown. 28 out of 30 samples were
found to be symptomatic and positive for Mumps IgM, indicating
active mumps infection in 93.4% of the vaccinated population. A
phylogenetic tree comparison of the clinical isolate is shown to be genotype C which is distinct from vaccine strain. Our study clearly sending warning signs that MMR vaccine is a failure and it needs to be revamped for the human use by increasing its efficacy and efficiency.
Abstract: A virtual collaborative classroom was created at East Carolina University, using videoconference technology via regular internet to bring students from 18 different countries, 2 at a time, to the ECU classroom in real time to learn about each other-s culture. Students from two countries are partnered one on one, they meet for 4-5 weeks, and submit a joint paper. Then the same process is repeated for two other countries. Lectures and student discussions are managed with pre-determined topics and questions. Classes are conducted in English and reading assignments are placed on the website. Administratively all partners are independent, students pay fees and get credits at their home institution. Familiarity with technology, knowledge in cultural understanding and attitude change were assessed, only attitude changes are reported in this paper. After taking this course, all students stated their comfort level in working with, and their desire to interact with, culturally different others grew stronger and their xenophobia and isolationist attitudes decreased.
Abstract: In the last few years, three multivariate spectral
analysis techniques namely, Principal Component Analysis (PCA),
Independent Component Analysis (ICA) and Non-negative Matrix
Factorization (NMF) have emerged as effective tools for oscillation
detection and isolation. While the first method is used in determining
the number of oscillatory sources, the latter two methods
are used to identify source signatures by formulating the detection
problem as a source identification problem in the spectral domain.
In this paper, we present a critical drawback of the underlying linear
(mixing) model which strongly limits the ability of the associated
source separation methods to determine the number of sources
and/or identify the physical source signatures. It is shown that the
assumed mixing model is only valid if each unit of the process gives
equal weighting (all-pass filter) to all oscillatory components in its
inputs. This is in contrast to the fact that each unit, in general, acts
as a filter with non-uniform frequency response. Thus, the model
can only facilitate correct identification of a source with a single
frequency component, which is again unrealistic. To overcome
this deficiency, an iterative post-processing algorithm that correctly
identifies the physical source(s) is developed. An additional issue
with the existing methods is that they lack a procedure to pre-screen
non-oscillatory/noisy measurements which obscure the identification
of oscillatory sources. In this regard, a pre-screening procedure
is prescribed based on the notion of sparseness index to eliminate
the noisy and non-oscillatory measurements from the data set used
for analysis.