Growth Effects of Caffeic Acid and Thioglycolic Acid Modified Chitosans in U937 Cells

Chitosan is a biopolymer composed of glucosamine and N-acetyl glucosamine. Solubility and viscosity pose problems in some applications. These problems can be overcome with unique modifications. In this study, firstly, chitosan was modified by caffeic acid and thioglycolic acid, separately. Then, growing effects of these modified polymers was observed in U937 cell line. Caffeic acid is a phenolic compound and its modifications act carcinogenic inhibitors in drugs. Thiolated chitosans are commonly being used for drugdelivery systems in various routes, because of enhancing mucoadhesiveness property. U937 cell line was used model cell for leukaemia. Modifications were achieved by 1 – 15 % binding range. Increasing binding ratios showed higher radical-scavenging activity and reducing cell growth, in compared to native chitosan. Caffeic acid modifications showed higher radical-scavenging activity than thiolated chitosans at the same concentrations. Caffeic acid and thioglycolic acid modifications inhibited growth of U937, effectively.

Game based Learning to Enhance Cognitive and Physical Capabilities of Elderly People: Concepts and Requirements

The last decade has seen an early majority of people The last decade, the role of the of the information communication technologies has increased in improving the social and business life of people. Today, it is recognized that game could contribute to enhance virtual rehabilitation by better engaging patients. Our research study aims to develop a game based system enhancing cognitive and physical capabilities of elderly people. To this end, the project aims to develop a low cost hand held system based on existing game such as Wii, PSP, or Xbox. This paper discusses the concepts and requirements for developing such game for elderly people. Based on the requirement elicitation, we intend to develop a prototype related to sport and dance activities.

Improvement of Synchronous Machine Dynamic Characteristics via Neural Network Based Controllers

This paper presents Simulation and experimental study aimed at investigating the effectiveness of an adaptive artificial neural network stabilizer on enhancing the damping torque of a synchronous generator. For this purpose, a power system comprising a synchronous generator feeding a large power system through a short tie line is considered. The proposed adaptive neuro-control system consists of two multi-layered feed forward neural networks, which work as a plant model identifier and a controller. It generates supplementary control signals to be utilized by conventional controllers. The details of the interfacing circuits, sensors and transducers, which have been designed and built for use in tests, are presented. The synchronous generator is tested to investigate the effect of tuning a Power System Stabilizer (PSS) on its dynamic stability. The obtained simulation and experimental results verify the basic theoretical concepts.

Prototype for Enhancing Information Security Awareness in Industry

Human-related information security breaches within organizations are primarily caused by employees who have not been made aware of the importance of protecting the information they work with. Information security awareness is accordingly attracting more attention from industry, because stakeholders are held accountable for the information with which they work. The authors developed an Information Security Retrieval and Awareness model – entitled “ISRA" – that is tailored specifically towards enhancing information security awareness in industry amongst all users of information, to address shortcomings in existing information security awareness models. This paper is principally aimed at expounding a prototype for the ISRA model to highlight the advantages of utilizing the model. The prototype will focus on the non-technical, humanrelated information security issues in industry. The prototype will ensure that all stakeholders in an organization are part of an information security awareness process, and that these stakeholders are able to retrieve specific information related to information security issues relevant to their job category, preventing them from being overburdened with redundant information.

Network State Classification based on the Statistical properties of RTT for an Adaptive Multi-State Proactive Transport Protocol for Satellite based Networks

This paper attempts to establish the fact that Multi State Network Classification is essential for performance enhancement of Transport protocols over Satellite based Networks. A model to classify Multi State network condition taking into consideration both congestion and channel error is evolved. In order to arrive at such a model an analysis of the impact of congestion and channel error on RTT values has been carried out using ns2. The analysis results are also reported in the paper. The inference drawn from this analysis is used to develop a novel statistical RTT based model for multi state network classification. An Adaptive Multi State Proactive Transport Protocol consisting of Proactive Slow Start, State based Error Recovery, Timeout Action and Proactive Reduction is proposed which uses the multi state network state classification model. This paper also confirms through detail simulation and analysis that a prior knowledge about the overall characteristics of the network helps in enhancing the performance of the protocol over satellite channel which is significantly affected due to channel noise and congestion. The necessary augmentation of ns2 simulator is done for simulating the multi state network classification logic. This simulation has been used in detail evaluation of the protocol under varied levels of congestion and channel noise. The performance enhancement of this protocol with reference to established protocols namely TCP SACK and Vegas has been discussed. The results as discussed in this paper clearly reveal that the proposed protocol always outperforms its peers and show a significant improvement in very high error conditions as envisaged in the design of the protocol.

DEA ANN Approach in Supplier Evaluation System

In Supply Chain Management (SCM), strengthening partnerships with suppliers is a significant factor for enhancing competitiveness. Hence, firms increasingly emphasize supplier evaluation processes. Supplier evaluation systems are basically developed in terms of criteria such as quality, cost, delivery, and flexibility. Because there are many variables to be analyzed, this process becomes hard to execute and needs expertise. On this account, this study aims to develop an expert system on supplier evaluation process by designing Artificial Neural Network (ANN) that is supported with Data Envelopment Analysis (DEA). The methods are applied on the data of 24 suppliers, which have longterm relationships with a medium sized company from German Iron and Steel Industry. The data of suppliers consists of variables such as material quality (MQ), discount of amount (DOA), discount of cash (DOC), payment term (PT), delivery time (DT) and annual revenue (AR). Meanwhile, the efficiency that is generated by using DEA is added to the supplier evaluation system in order to use them as system outputs.

Stress Intensity Factors for Plates with Collinear and Non-Aligned Straight Cracks

Multi-site damage (MSD) has been a challenge to aircraft, civil and power plant structures. In real life components are subjected to cracking at many vulnerable locations such as the bolt holes. However, we do not consider for the presence of multiple cracks. Unlike components with a single crack, these components are difficult to predict. When two cracks approach one another, their stress fields influence each other and produce enhancing or shielding effect depending on the position of the cracks. In the present study, numerical studies on fracture analysis have been conducted by using the developed code based on the modified virtual crack closure integral (MVCCI) technique and finite element analysis (FEA) software ABAQUS for computing SIF of plates with multiple cracks. Various parametric studies have been carried out and the results have been compared with literature where ever available and also with the solution, obtained by using ABAQUS. By conducting extensive numerical studies expressions for SIF have been obtained for collinear cracks and non-aligned cracks.

Enhancing the Error-Correcting Performance of LDPC Codes through an Efficient Use of Decoding Iterations

The decoding of Low-Density Parity-Check (LDPC) codes is operated over a redundant structure known as the bipartite graph, meaning that the full set of bit nodes is not absolutely necessary for decoder convergence. In 2008, Soyjaudah and Catherine designed a recovery algorithm for LDPC codes based on this assumption and showed that the error-correcting performance of their codes outperformed conventional LDPC Codes. In this work, the use of the recovery algorithm is further explored to test the performance of LDPC codes while the number of iterations is progressively increased. For experiments conducted with small blocklengths of up to 800 bits and number of iterations of up to 2000, the results interestingly demonstrate that contrary to conventional wisdom, the error-correcting performance keeps increasing with increasing number of iterations.

Specialized Web Robot for Objectionable Web Content Classification

This paper proposes a specialized Web robot to automatically collect objectionable Web contents for use in an objectionable Web content classification system, which creates the URL database of objectionable Web contents. It aims at shortening the update period of the DB, increasing the number of URLs in the DB, and enhancing the accuracy of the information in the DB.

The Role of Periodic Vortex Shedding in Heat Transfer Enhancement for Transient Pulsatile Flow Inside Wavy Channels

Periodic vortex shedding in pulsating flow inside wavy channel and the effect it has on heat transfer are studied using the finite volume method. A sinusoidally-varying component is superimposed on a uniform flow inside a sinusoidal wavy channel and the effects on the Nusselt number is analyzed. It was found that a unique optimum value of the pulsation frequency, represented by the Strouhal number, exists for Reynolds numbers ranging from 125 to 1000. Results suggest that the gain in heat transfer is related to the process of vortex formation, movement about the troughs of the wavy channel, and subsequent ejection/destruction through the converging section. Heat transfer is the highest when the frequencies of the pulsation and vortex formation approach being in-phase. Analysis of Strouhal number effect on Nu over a period of pulsation substantiates the proposed physical mechanism for enhancement. The effect of changing the amplitude of pulsation is also presented over a period of pulsation, showing a monotonic increase in heat transfer with increasing amplitude. The 60% increase in Nusselt number suggests that sinusoidal fluid pulsation can an effective method for enhancing heat transfer in laminar, wavy-channel flows.

On-line Speech Enhancement by Time-Frequency Masking under Prior Knowledge of Source Location

This paper presents the source extraction system which can extract only target signals with constraints on source localization in on-line systems. The proposed system is a kind of methods for enhancing a target signal and suppressing other interference signals. But, the performance of proposed system is superior to any other methods and the extraction of target source is comparatively complete. The method has a beamforming concept and uses an improved time-frequency (TF) mask-based BSS algorithm to separate a target signal from multiple noise sources. The target sources are assumed to be in front and test data was recorded in a reverberant room. The experimental results of the proposed method was evaluated by the PESQ score of real-recording sentences and showed a noticeable speech enhancement.