Abstract: Infection by group A streptococci (GAS) can trigger an autoantibody that cause a poststreptococcal reactive arthritis (PSRA). Four patients with PSRA aged 10 years to 14 years old with the main complaint of joint pain for five days to 10 days after suffering a fever and sore throat. The joint pain was persistent, additive, and non migratory. All patients revealed an increase in erythrocyte sedimentation rate (ESR) and anti-streptolysin O (ASLO), but the chest x-ray, electrocardiography, and echocardiography were normal. Bone imaging showed no destruction on the affected joint. Jones Criteria were not fulfilled in all patients. Erythromycin and ibuprofen were given in all patients and an improvement was shown. Erythromycin was continued for one year and routine controls were conducted for cardiac evaluation. The prognosis of all the patients was good.
Abstract: We formulate and analyze a mathematical model
describing dynamics of the hypothalamus-pituitary-thyroid
homoeostatic mechanism in endocrine system. We introduce
to this system two types of couplings and delay. In our model,
feedback controls the secretion of thyroid hormones and delay
reflects time lags required for transportation of the hormones. The
influence of delayed feedback on the stability behaviour of the
system is discussed. Analytical results are illustrated by numerical
examples of the model dynamics. This system of equations describes
normal activity of the thyroid and also a couple of types of
malfunctions (e.g. hyperthyroidism).
Abstract: This study developed a plug-in hybrid powertrain system which consisted of two continuous variable transmissions. By matching between the engine, motor, generator, and dual continuous variable transmissions, this integrated power system can take advantages of the components. The hybrid vehicle can be driven by the internal combustion engine, or electric motor alone, or by these two power sources together when the vehicle is driven in hard acceleration or high load. The energy management of this integrated hybrid system controls the power systems based on rule-based control strategy to achieve better fuel economy. When the vehicle driving power demand is low, the internal combustion engine is operating in the low efficiency region, so the internal combustion engine is shut down, and the vehicle is driven by motor only. When the vehicle driving power demand is high, internal combustion engine would operate in the high efficiency region; then the vehicle could be driven by internal combustion engine. This strategy would operate internal combustion engine only in optimal efficiency region to improve the fuel economy. In this research, the vehicle simulation model was built in MATLAB/ Simulink environment. The analysis results showed that the power coupled efficiency of the hybrid powertrain system with dual continuous variable transmissions was better than that of the Honda hybrid system on the market.
Abstract: The present study investigated approaches and techniques to enhance strategic management governance and decision making within the framework of a performance-based balanced scorecard. The review of best practices from strategic, program, process, and systems engineering management provided for a holistic approach toward effective outcome-based capability management. One technique, based on factorial experimental design methods, was used to develop an empirical model. This model predicted the degree of capability effectiveness and is dependent on controlled system input variables and their weightings. These variables represent business performance measures, captured within a strategic balanced scorecard. The weighting of these measures enhances the ability to quantify causal relationships within balanced scorecard strategy maps. The focus in this study was on the performance of tangible assets within the scorecard rather than the traditional approach of assessing performance of intangible assets such as knowledge and technology. Tangible assets are represented in this study as physical systems, which may be thought of as being aboard a ship or within a production facility. The measures assigned to these systems include project funding for upgrades against demand, system certifications achieved against those required, preventive maintenance to corrective maintenance ratios, and material support personnel capacity against that required for supporting respective systems. The resultant scorecard is viewed as complimentary to the traditional balanced scorecard for program and performance management. The benefits from these scorecards are realized through the quantified state of operational capabilities or outcomes. These capabilities are also weighted in terms of priority for each distinct system measure and aggregated and visualized in terms of overall state of capabilities achieved. This study proposes the use of interactive controls within the scorecard as a technique to enhance development of alternative solutions in decision making. These interactive controls include those for assigning capability priorities and for adjusting system performance measures, thus providing for what-if scenarios and options in strategic decision-making. In this holistic approach to capability management, several cross functional processes were highlighted as relevant amongst the different management disciplines. In terms of assessing an organization’s ability to adopt this approach, consideration was given to the P3M3 management maturity model.
Abstract: Mobile applications are being used to perform a wide variety of tasks in day-to-day life, ranging from checking email to controlling your home heating. Application developers have recognized the potential to transform a smart device into a medical device, by using a mobile medical application i.e. a mobile phone or a tablet. When initially conceived these mobile medical applications performed basic functions e.g. BMI calculator, accessing reference material etc.; however, increasing complexity offers clinicians and patients a range of functionality. As this complexity and functionality increases, so too does the potential risk associated with using such an application. Examples include any applications that provide the ability to inflate and deflate blood pressure cuffs, as well as applications that use patient-specific parameters and calculate dosage or create a dosage plan for radiation therapy. If an unapproved mobile medical application is marketed by a medical device organization, then they face significant penalties such as receiving an FDA warning letter to cease the prohibited activity, fines and possibility of facing a criminal conviction. Regulatory bodies have finalized guidance intended for mobile application developers to establish if their applications are subject to regulatory scrutiny. However, regulatory controls appear contradictory with the approaches taken by mobile application developers who generally work with short development cycles and very little documentation and as such, there is the potential to stifle further improvements due to these regulations. The research presented as part of this paper details how by adopting development techniques, such as agile software development, mobile medical application developers can meet regulatory requirements whilst still fostering innovation.
Abstract: In recent years, increasing the usage of railway transportations especially in developing countries caused more attention to control systems railway vehicles. Consequently, designing and implementing the modern control systems to improve the operating performance of trains and locomotives become one of the main concerns of researches. Dynamic braking systems is an important safety system which controls the amount of braking torque generated by traction motors, to keep the adhesion coefficient between the wheel-sets and rail road in optimum bound. Adhesion force has an important role to control the braking distance and prevent the wheels from slipping during the braking process. Cascade control structure is one of the best control methods for the wide range of industrial plants in the presence of disturbances and errors. This paper presents cascade control structure based on two forward simple controllers with two feedback loops to control the slip ratio and braking torque. In this structure, the inner loop controls the angular velocity and the outer loop control the longitudinal velocity of the locomotive that its dynamic is slower than the dynamic of angular velocity. This control structure by controlling the torque of DC traction motors, tries to track the desired velocity profile to access the predefined braking distance and to control the slip ratio. Simulation results are employed to show the effectiveness of the introduced methodology in dynamic braking system.
Abstract: We present a method to set up system functions
through a near filed communication (NFC) of a smartphone. The
short communication distance of the NFC which is usually less
than 4 cm could prevent any interferences from other devices and
establish a secure communication channel between a system and the
smartphone. The proposed set-up method for system function values
is demonstrated for a blacbox system in a car. In demonstration,
system functions of a blackbox which is manipulated through NFC
of a smartphone are controls of image quality, sound level, shock
sensing level to store images, etc. The proposed set-up method for
system function values can be used for any devices with NFC.
Abstract: The formula project of Kinki University has been involved in the student Formula SAE of Japan (JSAE) since the second year the competition was held. The vehicle developed in the project uses a ZX-6R engine, which has been manufactured by Kawasaki Heavy Industries for the JSAE competition for the eighth time. The limited performance of the concept vehicle was improved through the development of a power train. The supercharger loading, engine dry sump, and engine cooling management of the vehicle were also enhanced. The supercharger loading enabled the vehicle to achieve a maximum output of 59.6 kW (80.6 PS)/9000 rpm and a maximum torque of 70.6 Nm (7.2 kgf m)/8000 rpm. We successfully achieved 90% of the engine’s torque band (4000–10000 rpm) with 50% of the revolutions in regular engine use (2000–12000 rpm). Using a dry sump system, we periodically managed hydraulic pressure during engine operation. A system that controls engine stoppage when hydraulic pressure falls was also constructed. Using the dry sump system at 80 mm reduced the required engine load and the vehicle’s center of gravity. Even when engine motion was suspended by the electromotive force exerted by the water pump, the circulation of cooling water was still possible. These findings enabled us to create a cooling system in accordance with the requirements of the competition.
Abstract: Information system risk management helps to reduce
or eliminate risk by implementing appropriate controls. In this paper,
we propose a quantification model of controls impact on information
system risks by automatizing the residual criticality estimation step of
FMECA which is based on a inductive reasoning. For this, we defined
three equations based on type and maturity of controls. For testing,
the values obtained with the model were compared to estimated
values given by interlocutors during different working sessions and
the result is satisfactory. This model allows an optimal assessment of
controls maturity and facilitates risk analysis of information system.
Abstract: This paper presents a digital non-linear pulse-width modulation (PWM) controller in a high-voltage (HV) buck-boost DC-DC converter for the piezoelectric transducer of the down-hole acoustic telemetry system. The proposed design controls the generation of output signal with voltage higher than the supply voltage and is targeted to work under high temperature. To minimize the power consumption and silicon area, a simple and efficient design scheme is employed to develop the PWM controller. The proposed PWM controller consists of serial to parallel (S2P) converter, data assign block, a mode and duty cycle controller (MDC), linearly PWM (LPWM) and noise shaper, pulse generator and clock generator. To improve the reliability of circuit operation at higher temperature, this design is fabricated with the 1.0-μm silicon-on-insulator (SOI) CMOS process. The implementation results validated that the proposed design has the advantages of smaller size, lower power consumption and robust thermal stability.
Abstract: The paper presents the results of the molecular
genetics analysis in sports research, with special emphasis to use
genetic information in diagnosing of motoric predispositions in Roma
boys from East Slovakia. The ability and move are the basic
characteristics of all living organisms. The phenotypes are influenced
by a combination of genetic and environmental factors. Genetic tests
differ in principle from the traditional motoric tests, because
the DNA of an individual does not change during life. The aim of
the presented study was to examine motion abilities and to determine
the frequency of ACTN3 (R577X) gene in Roma children. Genotype
data were obtained from 138 Roma and 155 Slovak boys from 7 to 15
years old. Children were investigated on physical performance level
in association with their genotype. Biological material for genetic
analyses comprised samples of buccal swabs. Genotypes were
determined using Real Time High resolution melting PCR method
(Rotor-Gene 6000 Corbett and Light Cycler 480 Roche). The
software allows creating reports of any analysis, where information
of the specific analysis, normalized and differential graphs and many
information of the samples are shown. Roma children of analyzed
group legged to non-Romany children at the same age in all the
compared tests. The % distribution of R and X alleles in Roma
children was different from controls. The frequency of XX genotype
was 9.26%, RX 46.33% and RR was 44.41%. The frequency of XX
genotype was 9.26% which is comparable to a frequency of an Indian
population. Data were analyzed with the ANOVA test.
Abstract: Liver segmentation from medical images poses more
challenges than analogous segmentations of other organs. This
contribution introduces a liver segmentation method from a series of
computer tomography images. Overall, we present a novel method for
segmenting liver by coupling density matching with shape priors.
Density matching signifies a tracking method which operates via
maximizing the Bhattacharyya similarity measure between the
photometric distribution from an estimated image region and a model
photometric distribution. Density matching controls the direction of
the evolution process and slows down the evolving contour in regions
with weak edges. The shape prior improves the robustness of density
matching and discourages the evolving contour from exceeding liver’s
boundaries at regions with weak boundaries. The model is
implemented using a modified distance regularized level set (DRLS)
model. The experimental results show that the method achieves a
satisfactory result. By comparing with the original DRLS model, it is
evident that the proposed model herein is more effective in addressing
the over segmentation problem. Finally, we gauge our performance of
our model against matrices comprising of accuracy, sensitivity, and
specificity.
Abstract: Anogeissus leiocarpus (Combretaceae) is well known
for its medicinal uses in African traditional medicine, for treating
many human diseases mainly skin diseases and infections. Mycetoma
disease is a fungal and/ or bacterial skininfection, mainly cause by
Madurella mycetomatis fungus. This study was carried out in vitro to
investigate the antifungal activity of Anogeissus leiocarpus leaf
extracts against the isolated pathogenic Madurella mycetomatis, by
using the NCCLS modified method compared to Ketoconazole
standard drug, and MTT assay. The bioactive fraction was subjected
to chemical analysis implementing different chromatographic
analytical methods (TLC, HPLC, and LC-MS/MS). The results
showed significance antifungal activity of A. leiocarpus leaf extracts
against the isolated pathogenic M. mycetomatis, compared to negative
and positive controls. The chloroform fraction showed the highest
antifungal activity. The chromatographic analysis of the chloroform
fraction with the highest activity showed the presence of important
bioactive compounds such as ellagic and flavellagic acids derivatives,
flavonoids and stilbenoid, which are well known for their antifungal
activity.
Abstract: Detecting changes in multiple images of the same
scene has recently seen increased interest due to the many
contemporary applications including smart security systems, smart
homes, remote sensing, surveillance, medical diagnosis, weather
forecasting, speed and distance measurement, post-disaster forensics
and much more. These applications differ in the scale, nature, and
speed of change. This paper presents an application of image
processing techniques to implement a real-time change detection
system. Change is identified by comparing the RGB representation of
two consecutive frames captured in real-time. The detection threshold
can be controlled to account for various luminance levels. The
comparison result is passed through a filter before decision making to
reduce false positives, especially at lower luminance conditions. The
system is implemented with a MATLAB Graphical User interface
with several controls to manage its operation and performance.
Abstract: Fresh water is one of the resources which is getting
depleted day by day. A wise method to address this issue is by the
application of renewable energy-sun irradiation and by means of
decentralized, cheap, energetically self-sufficient, robust and simple
to operate plants, distillates can be obtained from sea, river or even
sewage. Solar desalination is a technique used to desalinate water
using solar energy. The present work deals with the comprehensive
design and simulation of solar tracking system using LabVIEW,
temperature and mass flow rate control of the solar desalination plant
using LabVIEW and also analysis of single phase inverter circuit
with LC filters for solar pumping system in MATLAB. The main
objective of this work is to improve the performance of solar
desalination system using automatic tracking system, output control
using temperature and mass flow rate control system and also to
reduce the harmonic distortion in the solar pumping system by means
of LC filters. The simulation of single phase inverter was carried out
using MATLAB and the output waveforms were analyzed.
Simulations were performed for optimum output temperature control,
which in turn controls the mass flow rate of water in the thermal
collectors. Solar tracking system was accomplished using LABVIEW
and was tested successfully. The thermal collectors are tracked in
accordance with the sun’s irradiance levels, thereby increasing the
efficiency of the thermal collectors.
Abstract: Cholera is a disease that is predominately common in
developing countries due to poor sanitation and overcrowding
population. In this paper, a deterministic model for the dynamics of
cholera is developed and control measures such as health educational
message, therapeutic treatment, and vaccination are incorporated in
the model. The effective reproduction number is computed in terms
of the model parameters. The existence and stability of the
equilibrium states, disease free and endemic equilibrium states are
established and showed to be locally and globally asymptotically
stable when R0 < 1 and R0 > 1 respectively. The existence of
backward bifurcation of the model is investigated. Furthermore,
numerical simulation of the model developed is carried out to show
the impact of the control measures and the result indicates that
combined control measures will help to reduce the spread of cholera
in the population.
Abstract: Lyophilization, also called freeze-drying, is an
important dehydration technique mainly used for pharmaceuticals.
Food industry also uses lyophilization when it is important to retain
most of the nutritional quality, taste, shape and size of dried products
and to extend their shelf life. Vacuum-Induced during freezing cycle
(VI) has been used in order to control ice nucleation and,
consequently, to reduce the time of primary drying cycle of
pharmaceuticals preserving quality properties of the final product.
This procedure has not been applied in freeze drying of foods. The
present work aims to investigate the effect of VI on the lyophilization
drying time, final moisture content, density and reconstitutional
properties of mango (Mangifera indica L.) slices (MS) and mango
pulp-maltodextrin dispersions (MPM) (30% concentration of total
solids). Control samples were run at each freezing rate without using
induced vacuum. The lyophilization endpoint was the same for all
treatments (constant difference between capacitance and Pirani
vacuum gauges). From the experimental results it can be concluded
that at the high freezing rate (0.4°C/min) reduced the overall process
time up to 30% comparing process time required for the control and
VI of the lower freeze rate (0.1°C/min) without affecting the quality
characteristics of the dried product, which yields a reduction in costs
and energy consumption for MS and MPM freeze drying. Controls
and samples treated with VI at freezing rate of 0.4°C/min in MS
showed similar results in moisture and density parameters.
Furthermore, results from MPM dispersion showed favorable values
when VI was applied because dried product with low moisture
content and low density was obtained at shorter process time
compared with the control. There were not found significant
differences between reconstitutional properties (rehydration for MS
and solubility for MPM) of freeze dried mango resulting from
controls, and VI treatments.
Abstract: During welding or flame cutting of metals, the
prediction of heat affected zone (HAZ) is critical. There is need to
develop a simple mathematical model to calculate the temperature
variation in HAZ and derivative analysis can be used for this purpose.
This study presents analytical solution for heat transfer through
conduction in mild steel plate. The homogeneous and nonhomogeneous
boundary conditions are single variables. The full field
analytical solutions of temperature measurement, subjected to local
heating source, are derived first by method of separation of variables
followed with the experimental visualization using infrared imaging.
Based on the present work, it is suggested that appropriate heat input
characteristics controls the temperature distribution in and around
HAZ.
Abstract: The end of the line controls of the finished products in
the automotive industry is important. The control that has been
conducted with the manual methods for the sliding doors tracks is not
sufficient and faulty products cannot be identified. As a result, the
customer has the faulty products. In the scope of this study, the
design criteria of the PLC integrated modular end of line control unit
has been examined, designed and manufactured to make the control
of the 10 different track profile to 2 different vehicles with an
objective to minimize the salvage costs by obtaining more sensitive,
certain and accurate measurement results. In the study that started
with literature and patent review, the design inputs have been
specified, the technical concept has been developed, computer
supported mechanic design, control system and automation design,
design review and design improvement have been made. Laser
analog sensors at high sensitivity, probes and modular blocks have
been used in the unit. The measurement has been conducted in the
system and it is observed that measurement results are more sensitive
than the previous methods that we use.
Abstract: This paper presents the interface ConductHome which
controls home automation systems with a Leap Motion using
“invariant gesture protocols”. This interface is meant to simplify the
interaction of the user with its environment. A hardware part allows
the Leap Motion to be carried around the house. A software part
interacts with the home automation box and displays the useful
information for the user. An objective of this work is the
development of a natural/invariant/simple gesture control interface to
help elder people/people with disabilities.