A New Hybrid K-Mean-Quick Reduct Algorithm for Gene Selection

Feature selection is a process to select features which are more informative. It is one of the important steps in knowledge discovery. The problem is that all genes are not important in gene expression data. Some of the genes may be redundant, and others may be irrelevant and noisy. Here a novel approach is proposed Hybrid K-Mean-Quick Reduct (KMQR) algorithm for gene selection from gene expression data. In this study, the entire dataset is divided into clusters by applying K-Means algorithm. Each cluster contains similar genes. The high class discriminated genes has been selected based on their degree of dependence by applying Quick Reduct algorithm to all the clusters. Average Correlation Value (ACV) is calculated for the high class discriminated genes. The clusters which have the ACV value as 1 is determined as significant clusters, whose classification accuracy will be equal or high when comparing to the accuracy of the entire dataset. The proposed algorithm is evaluated using WEKA classifiers and compared. The proposed work shows that the high classification accuracy.

Covering-based Rough sets Based on the Refinement of Covering-element

Covering-based rough sets is an extension of rough sets and it is based on a covering instead of a partition of the universe. Therefore it is more powerful in describing some practical problems than rough sets. However, by extending the rough sets, covering-based rough sets can increase the roughness of each model in recognizing objects. How to obtain better approximations from the models of a covering-based rough sets is an important issue. In this paper, two concepts, determinate elements and indeterminate elements in a universe, are proposed and given precise definitions respectively. This research makes a reasonable refinement of the covering-element from a new viewpoint. And the refinement may generate better approximations of covering-based rough sets models. To prove the theory above, it is applied to eight major coveringbased rough sets models which are adapted from other literature. The result is, in all these models, the lower approximation increases effectively. Correspondingly, in all models, the upper approximation decreases with exceptions of two models in some special situations. Therefore, the roughness of recognizing objects is reduced. This research provides a new approach to the study and application of covering-based rough sets.

Dynamic Features Selection for Heart Disease Classification

The healthcare environment is generally perceived as being information rich yet knowledge poor. However, there is a lack of effective analysis tools to discover hidden relationships and trends in data. In fact, valuable knowledge can be discovered from application of data mining techniques in healthcare system. In this study, a proficient methodology for the extraction of significant patterns from the Coronary Heart Disease warehouses for heart attack prediction, which unfortunately continues to be a leading cause of mortality in the whole world, has been presented. For this purpose, we propose to enumerate dynamically the optimal subsets of the reduced features of high interest by using rough sets technique associated to dynamic programming. Therefore, we propose to validate the classification using Random Forest (RF) decision tree to identify the risky heart disease cases. This work is based on a large amount of data collected from several clinical institutions based on the medical profile of patient. Moreover, the experts- knowledge in this field has been taken into consideration in order to define the disease, its risk factors, and to establish significant knowledge relationships among the medical factors. A computer-aided system is developed for this purpose based on a population of 525 adults. The performance of the proposed model is analyzed and evaluated based on set of benchmark techniques applied in this classification problem.

An Intelligent Approach of Rough Set in Knowledge Discovery Databases

Knowledge Discovery in Databases (KDD) has evolved into an important and active area of research because of theoretical challenges and practical applications associated with the problem of discovering (or extracting) interesting and previously unknown knowledge from very large real-world databases. Rough Set Theory (RST) is a mathematical formalism for representing uncertainty that can be considered an extension of the classical set theory. It has been used in many different research areas, including those related to inductive machine learning and reduction of knowledge in knowledge-based systems. One important concept related to RST is that of a rough relation. In this paper we presented the current status of research on applying rough set theory to KDD, which will be helpful for handle the characteristics of real-world databases. The main aim is to show how rough set and rough set analysis can be effectively used to extract knowledge from large databases.