Abstract: Recently GPS data is used in a lot of studies to
automatically reconstruct travel patterns for trip survey. The aim is to
minimize the use of questionnaire surveys and travel diaries so as to
reduce their negative effects. In this paper data acquired from GPS and
accelerometer embedded in smart phones is utilized to predict the
mode of transportation used by the phone carrier. For prediction,
Support Vector Machine (SVM) and Adaptive boosting (AdaBoost)
are employed. Moreover a unique method to improve the prediction
results from these algorithms is also proposed. Results suggest that the
prediction accuracy of AdaBoost after improvement is relatively better
than the rest.
Abstract: Protein-protein interactions (PPI) play a crucial role in many biological processes such as cell signalling, transcription, translation, replication, signal transduction, and drug targeting, etc. Structural information about protein-protein interaction is essential for understanding the molecular mechanisms of these processes. Structures of protein-protein complexes are still difficult to obtain by biophysical methods such as NMR and X-ray crystallography, and therefore protein-protein docking computation is considered an important approach for understanding protein-protein interactions. However, reliable prediction of the protein-protein complexes is still under way. In the past decades, several grid-based docking algorithms based on the Katchalski-Katzir scoring scheme were developed, e.g., FTDock, ZDOCK, HADDOCK, RosettaDock, HEX, etc. However, the success rate of protein-protein docking prediction is still far from ideal. In this work, we first propose a more practical measure for evaluating the success of protein-protein docking predictions,the rate of first success (RFS), which is similar to the concept of mean first passage time (MFPT). Accordingly, we have assessed the ZDOCK bound and unbound benchmarks 2.0 and 3.0. We also createda new benchmark set for protein-protein docking predictions, in which the complexes have experimentally determined binding affinity data. We performed free energy calculation based on the solution of non-linear Poisson-Boltzmann equation (nlPBE) to improve the binding mode prediction. We used the well-studied thebarnase-barstarsystem to validate the parameters for free energy calculations. Besides,thenlPBE-based free energy calculations were conducted for the badly predicted cases by ZDOCK and ZRANK. We found that direct molecular mechanics energetics cannot be used to discriminate the native binding pose from the decoys.Our results indicate that nlPBE-based calculations appeared to be one of the promising approaches for improving the success rate of binding pose predictions.
Abstract: The H.264/AVC video coding standard contains a number of advanced features. Ones of the new features introduced in this standard is the multiple intramode prediction. Its function exploits directional spatial correlation with adjacent block for intra prediction. With this new features, intra coding of H.264/AVC offers a considerably higher improvement in coding efficiency compared to other compression standard, but computational complexity is increased significantly when brut force rate distortion optimization (RDO) algorithm is used. In this paper, we propose a new fast intra prediction mode decision method for the complexity reduction of H.264 video coding. for luma intra prediction, the proposed method consists of two step: in the first step, we make the RDO for four mode of intra 4x4 block, based the distribution of RDO cost of those modes and the idea that the fort correlation with adjacent mode, we select the best mode of intra 4x4 block. In the second step, we based the fact that the dominating direction of a smaller block is similar to that of bigger block, the candidate modes of 8x8 blocks and 16x16 macroblocks are determined. So, in case of chroma intra prediction, the variance of the chroma pixel values is much smaller than that of luma ones, since our proposed uses only the mode DC. Experimental results show that the new fast intra mode decision algorithm increases the speed of intra coding significantly with negligible loss of PSNR.
Abstract: The H.264/AVC standard uses an intra prediction, 9
directional modes for 4x4 luma blocks and 8x8 luma blocks, 4
directional modes for 16x16 macroblock and 8x8 chroma blocks,
respectively. It means that, for a macroblock, it has to perform 736
different RDO calculation before a best RDO modes is determined.
With this Multiple intra-mode prediction, intra coding of H.264/AVC
offers a considerably higher improvement in coding efficiency
compared to other compression standards, but computational
complexity is increased significantly. This paper presents a fast intra
prediction algorithm for H.264/AVC intra prediction based a
characteristic of homogeneity information. In this study, the gradient
prediction method used to predict the homogeneous area and the
quadratic prediction function used to predict the nonhomogeneous
area. Based on the correlation between the homogeneity and block
size, the smaller block is predicted by gradient prediction and
quadratic prediction, so the bigger block is predicted by gradient
prediction. Experimental results are presented to show that the
proposed method reduce the complexity by up to 76.07%
maintaining the similar PSNR quality with about 1.94%bit rate
increase in average.