Abstract: Leishmaniasis is the collective name for a number of
diseases caused by protozoan flagellates of the genus Leishmania,
which is transmitted by Phlebotomine sandfly, the disease has diverse
clinical manifestations and found in many areas of the world,
particularly in Africa, Latin America, South and Central Asia, the
Mediterranean basin and the Middle East. This study was done to
assess primary health care physicians’ knowledge (PHP) and attitude
about leishmaniasis and to assess awareness of local inhabitants
about the disease and its vector in four areas in west Alexandria,
Egypt. It is a cross sectional survey that was conducted in four PHC
units in west Alexandria. All physicians currently working in these
units during the study period were invited to participate in the study;
only 20 PHP completed the questionnaire. 60 local inhabitants were
selected randomly from the four areas of the study, 15 from each
area; Data was collected through two different specially designed
questionnaires. Results showed that 11 (55%) percent of the
physicians had satisfactory knowledge; they answered more than 9
(60%) questions out of a total 14 questions about leishmaniasis and
sandfly. On the other hand when attitude of the primary health care
physicians about leishmaniasis was measured, results showed that 17
(85%) had good attitude and 3 (15%) had poor attitude. The second
questionnaire showed that the awareness of local inhabitants about
leishmaniasis and sandfly as a vector of the disease is poor and needs
to be corrected. (90%) of the interviewed inhabitants had not heard
about leishmaniasis, Only 3 (5%) of them said they know sandfly and
its role in transmission of leishmaniasis. Thus we conclude that
knowledge and attitudes of physicians are acceptable. However, there
is, room for improvement and could be done through formal training
courses and distribution of guidelines. In addition to raising the
awareness of primary health care physicians about the importance of
early detection and notification of cases of leishmaniasis, health
education for raising awareness of the public regarding the vector and
the disease is necessary because related studies have demonstrated
that for inhabitants to take enough protective measures against the
vector, they should perceive that it is responsible for causing a
disease.
Abstract: Medical applications are among the most impactful
areas of microrobotics. The ultimate goal of medical microrobots is
to reach currently inaccessible areas of the human body and carry out
a host of complex operations such as minimally invasive surgery
(MIS), highly localized drug delivery, and screening for diseases at
their very early stages. Miniature, safe and efficient propulsion
systems hold the key to maturing this technology but they pose
significant challenges. A new type of propulsion developed recently,
uses multi-flagella architecture inspired by the motility mechanism of
prokaryotic microorganisms. There is a lack of efficient methods for
designing this type of propulsion system. The goal of this paper is to
overcome the lack and this way, a numerical strategy is proposed to
design multi-flagella propulsion systems. The strategy is based on the
implementation of the regularized stokeslet and rotlet theory, RFT
theory and new approach of “local corrected velocity". The effects of
shape parameters and angular velocities of each flagellum on overall
flow field and on the robot net forces and moments are considered.
Then a multi-layer perceptron artificial neural network is designed
and employed to adjust the angular velocities of the motors for
propulsion control. The proposed method applied successfully on a
sample configuration and useful demonstrative results is obtained.
Abstract: Austenite and Martensite indicate the phases of solids undergoing phase transformation which we usually associate with materials and not with living organisms. This article provides an overview of bacterial proteins and structures that are undergoing phase transformation and suggests its probable effect on mechanical behavior. The context is mainly within the role of phase transformations occurring in the flagellum of bacteria. The current knowledge of molecular mechanism leading to phase variation in living organisms is reviewed. Since in bacteria, each flagellum is driven by a separate motor, similarity to a Differential drive in case of four-wheeled vehicles is suggested. It also suggests the application of the mechanism in which bacteria changes its direction of movement to facilitate single point turning of a multi-wheeled vehicle. Finally, examples are presented to illustrate that the motion due to phase transformation of flagella in bacteria can start a whole new research on motion mechanisms.
Abstract: According to FDA (Food and Drug Administration of the United States), vinegar is definedas a sour liquid containing at least 4 grams acetic acid in 100 cubic centimeter (4% solution of acetic acid) of solution that is produced from sugary materials by alcoholic fermentation. In the base of microbial starters, vinegars could be contained of more than 50 types of volatile and aromatic substances that responsible for their sweet taste and smelling. Recently the vinegar industry has a great proportion in agriculture, food and microbial biotechnology. The acetic acid bacteria are from the family Acetobacteraceae. Regarding to the latest version of Bergy-s Mannual of Systematic Bacteriology that has categorized bacteria in the base of their 16s RNA differences, the most important acetic acid genera are included Acetobacter (genus I), Gluconacetobacter (genus VIII) and Gluconobacter (genus IX). The genus Acetobacter that is primarily used in vinegar manufacturing plants is a gram negative, obligate aerobe coccus or rod shaped bacterium with the size 0.6 - 0.8 X 1.0 - 4.0 μm, nonmotile or motile with peritrichous flagella and catalase positive – oxidase negative biochemically. Some strains are overoxidizer that could convert acetic acid to carbon dioxide and water.In this research one Acetobacter native strain with high acetic acid productivity was isolated from Iranian white – red cherry. We used two specific culture media include Carr medium [yeast extract, 3%; ethanol, 2% (v/v); bromocresol green, 0.002%; agar, 2% and distilled water, 1000 ml], Frateur medium [yeast extract, 10 g/l; CaCO3, 20 g/l; ethanol, 20 g/l; agar, 20 g/l and distilled water, 1000 ml] and an industrial culture medium. In addition to high acetic acid production and high growth rate, this strain had a good tolerance against ethanol concentration that was examined using modified Carr media with 5%, 7% and 9% ethanol concentrations. While the industrial strains of acetic acid bacteria grow in the thermal range of 28 – 30 °C, this strain was adapted for growth in 34 – 36 °C after 96 hours incubation period. These dramatic characteristics suggest a potential biotechnological strain in production of cherry vinegar with a sweet smell and different nutritional properties in comparison to recent vinegar types. The lack of growth after 24, 48 and 72 hours incubation at 34 – 36 °C and the growth after 96 hours indicates a good and fast thermal flexibility of this strain as a significant characteristic of biotechnological and industrial strains.