Abstract: In order to enhance the knowledge of certain
phytochemical Algerian plants that are widely used in traditional
medicine and to exploit their therapeutic potential in modern
medicine, we have done a specific extraction of terpenes and
alkaloids from the leaves of Euphorbia granulata to evaluate the
antioxidant and antibacterial activity of this extracts. After the
extraction it was found that the terpene extract gave the highest yield
59.72% compared with alkaloids extracts.
The disc diffusion method was used to determine the antibacterial
activity against different bacterial strains: Escherichia coli
(ATCC25922), Pseudomonas aeruginosa (ATCC27853) and
Staphylococcus aureus (ATCC25923). All extracts have shown
inhibition of growth bacteria. The different zones of inhibition have
varied from (7 -10 mm) according to the concentrations of extract
used.
Testing the antiradical activity on DPPH-TLC plates indicated the
presence of substances that have potent anti-free radical. As against,
the BC-TLC revealed that only terpenes extract which was reacted
positively. These results can validate the importance of Euphorbia
granulata in traditional medicine.