Abstract: This study was investigated on sampling and
analyzing water quality in water reservoir & water tower installed in
two kind of residential buildings and school facilities. Data of water
quality was collected for correlation analysis with frequency of
sanitization of water reservoir through questioning managers of
building about the inspection charts recorded on equipment for water
reservoir. Statistical software packages (SPSS) were applied to the
data of two groups (cleaning frequency and water quality) for
regression analysis to determine the optimal cleaning frequency of
sanitization. The correlation coefficient (R) in this paper represented
the degree of correlation, with values of R ranging from +1 to -1.After
investigating three categories of drinking water users; this study found
that the frequency of sanitization of water reservoir significantly
influenced the water quality of drinking water. A higher frequency of
sanitization (more than four times per 1 year) implied a higher quality
of drinking water. Results indicated that sanitizing water reservoir &
water tower should at least twice annually for achieving the aim of
safety of drinking water.
Abstract: Ethanol is generally used as a therapeutic reagent against Hepatocellular carcinoma (HCC or hepatoma) worldwide, as it can induce Hepatocellular carcinoma cell apoptosis at low concentration through a multifactorial process regulated by several unknown proteins. This paper provides a simple and available proteomic strategy for exploring differentially expressed proteins in the apoptotic pathway. The appropriate concentrations of ethanol required to induce HepG2 cell apoptosis were first assessed by MTT assay, Gisma and fluorescence staining. Next, the central proteins involved in the apoptosis pathway processs were determined using 2D-PAGE, SDS-PAGE, and bio-software analysis. Finally the downregulation of two proteins, AFP and survivin, were determined by immunocytochemistry and reverse transcriptase PCR (RT-PCR) technology. The simple, useful method demonstrated here provides a new approach to proteomic analysis in key bio-regulating process including proliferation, differentiation, apoptosis, immunity and metastasis.
Abstract: We have measured the pressure drop and convective
heat transfer coefficient of water – based AL(25nm),AL2O3(30nm)
and CuO(50nm) Nanofluids flowing through a uniform heated
circular tube in the fully developed laminar flow regime. The
experimental results show that the data for Nanofluids friction factor
show a good agreement with analytical prediction from the Darcy's
equation for single-phase flow. After reducing the experimental
results to the form of Reynolds, Rayleigh and Nusselt numbers. The
results show the local Nusselt number and temperature have
distribution with the non-dimensional axial distance from the tube
entry. Study decided that thenNanofluid as Newtonian fluids through
the design of the linear relationship between shear stress and the rate
of stress has been the study of three chains of the Nanofluid with
different concentrations and where the AL, AL2O3 and CuO – water
ranging from (0.25 - 2.5 vol %). In addition to measuring the four
properties of the Nanofluid in practice so as to ensure the validity of
equations of properties developed by the researchers in this area and
these properties is viscosity, specific heat, and density and found that
the difference does not exceed 3.5% for the experimental equations
between them and the practical. The study also demonstrated that the
amount of the increase in heat transfer coefficient for three types of
Nano fluid is AL, AL2O3, and CuO – Water and these ratios are
respectively (45%, 32%, 25%) with insulation and without insulation
(36%, 23%, 19%), and the statement of any of the cases the best
increase in heat transfer has been proven that using insulation is
better than not using it. I have been using three types of Nano
particles and one metallic Nanoparticle and two oxide Nanoparticle
and a statement, whichever gives the best increase in heat transfer.
Abstract: This paper presents an advance in monitoring and
process control of surface roughness in CNC machine for the turning
and milling processes. An integration of the in-process monitoring
and process control of the surface roughness is proposed and
developed during the machining process by using the cutting force
ratio. The previously developed surface roughness models for turning
and milling processes of the author are adopted to predict the inprocess
surface roughness, which consist of the cutting speed, the
feed rate, the tool nose radius, the depth of cut, the rake angle, and
the cutting force ratio. The cutting force ratios obtained from the
turning and the milling are utilized to estimate the in-process surface
roughness. The dynamometers are installed on the tool turret of CNC
turning machine and the table of 5-axis machining center to monitor
the cutting forces. The in-process control of the surface roughness
has been developed and proposed to control the predicted surface
roughness. It has been proved by the cutting tests that the proposed
integration system of the in-process monitoring and the process
control can be used to check the surface roughness during the cutting
by utilizing the cutting force ratio.
Abstract: In this paper, a novel approach for the multidisciplinary design optimization (MDO) of complex mechatronic systems. This approach, which is a part of a global project aiming to include the MDO aspect inside an innovative design process. As a first step, the paper considers the MDO as a redesign approach which is limited to the parametric optimization. After defining and introducing the different keywords, the proposed method which is based on the V-Model which is commonly used in mechatronics.
Abstract: PCCI engines can reduce NOx and PM emissions
simultaneously without sacrificing thermal efficiency, but a low
combustion temperature resulting from early fuel injection, and
ignition occurring prior to TDC, can cause higher THC and CO
emissions and fuel consumption. In conclusion, it was found that the
PCCI combustion achieved by the 2-stage injection strategy with
optimized calibration factors (e.g. EGR rate, injection pressure, swirl
ratio, intake pressure, injection timing) can reduce NOx and PM
emissions simultaneously. This research works are expected to
provide valuable information conducive to a development of an
innovative combustion engine that can fulfill upcoming stringent
emission standards.
Abstract: One of the main advantages of the LO paradigm is to
allow the availability of good quality, shareable learning material
through the Web. The effectiveness of the retrieval process requires a
formal description of the resources (metadata) that closely fits the
user-s search criteria; in spite of the huge international efforts in this
field, educational metadata schemata often fail to fulfil this
requirement. This work aims to improve the situation, by the
definition of a metadata model capturing specific didactic features of
shareable learning resources. It classifies LOs into “teacher-oriented"
and “student-oriented" categories, in order to describe the role a LO
is to play when it is integrated into the educational process. This
article describes the model and a first experimental validation process
that has been carried out in a controlled environment.
Abstract: 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) catalyzes the conversion of HMG-CoA to mevalonate using NADPH and the enzyme is involved in rate-controlling step of mevalonate. Inhibition of HMGR is considered as effective way to lower cholesterol levels so it is drug target to treat hypercholesterolemia, major risk factor of cardiovascular disease. To discover novel HMGR inhibitor, we performed structure-based pharmacophore modeling combined with molecular dynamics (MD) simulation. Four HMGR inhibitors were used for MD simulation and representative structure of each simulation were selected by clustering analysis. Four structure-based pharmacophore models were generated using the representative structure. The generated models were validated used in virtual screening to find novel scaffolds for inhibiting HMGR. The screened compounds were filtered by applying drug-like properties and used in molecular docking. Finally, four hit compounds were obtained and these complexes were refined using energy minimization. These compounds might be potential leads to design novel HMGR inhibitor.
Abstract: The effect of extraction solvent upon properties
of carrageenan from Eucheuma cottonii was studied. The
distilled water and KOH solution (concentration 0.1- 0.5N) were
used as the solvent. Extraction process was carried out in water
bath equipped by stirrer with constant speed of 275 rpm with a
constant ratio of seaweed weight to solvent volume ( 1:50 g/mL)
at 86oC for 45 minutes. The extract was then precipitated in 3
volume of 90% ethanol, oven dried at 60oC. Based on
experimental data, alkali significantly influenced yield and
properties of extracted carrageenan. The extracted carrageenan
was found to have essentially identical FTIR spectra to the
reference samples of kappa-carrageenan. Increasing the KOH
concentration led to carrageenan containing less sulfate content
and intrinsic viscosity. The gel strength increased along with the
increasing of KOH concentration. The decreasing of intrinsic
viscosity value indicates that a polymer degradation occurs
during alkali extraction.
Abstract: For the first incumbent operator it is very important
to understand how to react when the second operator comes to the
market. In this paper which is prepared for preliminary study of
GSM market in Iran, we have studied five MENA markets
according to the similarity point of view. This paper aims at
analyzing the impact of second entrants in selected markets on
certain marketing key performance indicators (KPI) such as:
Market shares (by operator), prepaid share, minutes of use (MoU),
Price and average revenue per user (ARPU) (for total market
each).
Abstract: This paper explores the effectiveness of machine
learning techniques in detecting firms that issue fraudulent financial
statements (FFS) and deals with the identification of factors
associated to FFS. To this end, a number of experiments have been
conducted using representative learning algorithms, which were
trained using a data set of 164 fraud and non-fraud Greek firms in the
recent period 2001-2002. The decision of which particular method to
choose is a complicated problem. A good alternative to choosing
only one method is to create a hybrid forecasting system
incorporating a number of possible solution methods as components
(an ensemble of classifiers). For this purpose, we have implemented
a hybrid decision support system that combines the representative
algorithms using a stacking variant methodology and achieves better
performance than any examined simple and ensemble method. To
sum up, this study indicates that the investigation of financial
information can be used in the identification of FFS and underline the
importance of financial ratios.
Abstract: In single trial analysis, when using Principal
Component Analysis (PCA) to extract Visual Evoked Potential
(VEP) signals, the selection of principal components (PCs) is an
important issue. We propose a new method here that selects only
the appropriate PCs. We denote the method as selective eigen-rate
(SER). In the method, the VEP is reconstructed based on the rate
of the eigen-values of the PCs. When this technique is applied on
emulated VEP signals added with background
electroencephalogram (EEG), with a focus on extracting the
evoked P3 parameter, it is found to be feasible. The improvement
in signal to noise ratio (SNR) is superior to two other existing
methods of PC selection: Kaiser (KSR) and Residual Power (RP).
Though another PC selection method, Spectral Power Ratio (SPR)
gives a comparable SNR with high noise factors (i.e. EEGs), SER
give more impressive results in such cases. Next, we applied SER
method to real VEP signals to analyse the P3 responses for
matched and non-matched stimuli. The P3 parameters extracted
through our proposed SER method showed higher P3 response for
matched stimulus, which confirms to the existing neuroscience
knowledge. Single trial PCA using KSR and RP methods failed to
indicate any difference for the stimuli.
Abstract: The P-Bigram method is a string comparison methods
base on an internal two characters-based similarity measure. The edit
distance between two strings is the minimal number of elementary
editing operations required to transform one string into the other. The
elementary editing operations include deletion, insertion, substitution
two characters. In this paper, we address the P-Bigram method to
sole the similarity problem in DNA sequence. This method provided
an efficient algorithm that locates all minimum operation in a string.
We have been implemented algorithm and found that our program
calculated that smaller distance than one string. We develop PBigram
edit distance and show that edit distance or the similarity and
implementation using dynamic programming. The performance of
the proposed approach is evaluated using number edit and percentage
similarity measures.
Abstract: Chronic conditions carry with them strong emotions
and often lead to charged relationships between patients and their
health providers and, by extension, patients and health researchers.
Persons are both autonomous and relational and a purely cognitive
model of autonomy neglects the social and relational basis of chronic
illness. Ensuring genuine informed consent in research requires a
thorough understanding of how participants perceive a study and
their reasons for participation. Surveys may not capture the
complexities of reasoning that underlies study participation.
Contradictory reasons for participation, for instance an initial claim
of altruism as rationale and a subsequent claim of personal benefit
(therapeutic misconception), affect the quality of informed consent.
Individuals apply principles through the filter of personal values and
lived experience. Authentic autonomy, and hence authentic consent
to research, occurs within the context of patients- unique life
narratives and illness experiences.
Abstract: In this paper we propose a family of algorithms based
on 3rd and 4th order cumulants for blind single-input single-output
(SISO) Non-Minimum Phase (NMP) Finite Impulse Response (FIR)
channel estimation driven by non-Gaussian signal. The input signal
represents the signal used in 10GBASE-T (or IEEE 802.3an-2006)
as a Tomlinson-Harashima Precoded (THP) version of random
Pulse-Amplitude Modulation with 16 discrete levels (PAM-16). The
proposed algorithms are tested using three non-minimum phase
channel for different Signal-to-Noise Ratios (SNR) and for different
data input length. Numerical simulation results are presented to
illustrate the performance of the proposed algorithms.
Abstract: Grid composite structures have many applications in aerospace industry in which deal with transverse loadings abundantly. In present paper a stiffened composite cylindrical shell with clamped-free boundary condition under transverse end load experimentally and numerically was studied. Some electrical strain gauges were employed to measure the strains. Also a finite element analysis was done for validation of experimental result. The FEM software used was ANSYS11. In addition, the results between stiffened composite shell and unstiffened composite shell were compared. It was observed that intersection of two stiffeners has an important effect in decrease of stress in the shell. Fairly good agreements were observed between the numerical and the measured results. According to recent studies about grid composite structures, it should be noted that any investigation like this research has not been reported.
Abstract: System MEMORI automatically detects and recognizes rotated and/or rescaled versions of the objects of a database within digital color images with cluttered background. This task is accomplished by means of a region grouping algorithm guided by heuristic rules, whose parameters concern some geometrical properties and the recognition score of the database objects. This paper focuses on the strategies implemented in MEMORI for the estimation of the heuristic rule parameters. This estimation, being automatic, makes the system a highly user-friendly tool.
Abstract: In Korea, the technology of a load fo nuclear power plant has been being developed.
automatic controller which is able to control temperature and axial power distribution was developed. identification algorithm and a model predictive contact former transforms the nuclear reactor status into
numerically. And the latter uses them and ge
manipulated values such as two kinds of control ro
this automatic controller, the performance of a coperation was evaluated. As a result, the automatic generated model parameters of a nuclear react to nuclear reactor average temperature and axial power the desired targets during a daily load follow.
Abstract: All around the world pulp and paper industries are the
biggest plant production with the environmental pollution as the
biggest challenge facing the pulp manufacturing operations. The
concern among these industries is to produce a high volume of papers
with the high quality standard and of low cost without affecting the
environment. This result obtained from this bleaching study show
that the activation of peroxide was an effective method of reducing
the total applied charge of chlorine dioxide which is harmful to our
environment and also show that softwood and hardwood Kraft pulps
responded linearly to the peroxide treatments. During the bleaching
process the production plant produce chlorines. Under the trial stages
chloride dioxide has been reduced by 3 kg/ton to reduce the
brightness from 65% ISO to 60% ISO of pulp and the dosing point
returned to the E stage charges by pre-treating Kraft pulps with
hydrogen peroxide. The pulp and paper industry has developed
elemental chlorine free (ECF) and totally chlorine free (TCF)
bleaching, in their quest for being environmental friendly, they have
been looking at ways to turn their ECF process into a TCF process
while still being competitive. This prompted the research to
investigate the capability of the hydrogen peroxide as catalyst to
reduce chloride dioxide.
Abstract: In this competitive age, one of the key tools of most successful organizations is knowledge management. Today some organizations measure their current knowledge and use it as an indicator for rating the organization on their reports. Noting that the universities and colleges of medical science have a great role in public health of societies, their access to newest scientific research and the establishment of organizational knowledge management systems is very important. In order to explore the Application of Knowledge Management Factors, a national study was undertaken. The main purpose of this study was to find the rate of the application of knowledge management factors and some ways to establish more application of knowledge management system in Esfahan University-s Medical College (EUMC). Esfahan is the second largest city after Tehran, the capital city of Iran, and the EUMC is the biggest medical college in Esfahan. To rate the application of knowledge management, this study uses a quantitative research methodology based on Probst, Raub and Romhardt model of knowledge management. A group of 267 faculty members and staff of the EUMC were asked via questionnaire. Finding showed that the rate of the application of knowledge management factors in EUMC have been lower than average. As a result, an interview with ten faculty members conducted to find the guidelines to establish more applications of knowledge management system in EUMC.