Quantitative Analysis of Carcinoembryonic Antigen (CEA) Using Micromechanical Piezoresistive Cantilever

In this work, we have used arrays of micromechanical piezoresistive cantilever with different geometries to detect carcinoembryonic antigen (CEA), which is known as an important biomarker associated with various cancers such as colorectal, lung, breast, pancreatic, and bladder cancer. The sensing principle is based on the surface stress changes induced by antigen–antibody interaction on the microcantilevers surfaces. Different concentrations of CEA in a human serum albumin (HSA) solution were detected as a function of deflection of the beams. According to the experiments, it was revealed that microcantilevers have surface stress sensitivities in the order of 8 (mJ/m). This matter allows them to detect CEA concentrations as low as 3 ng/mL or 18 pM. This indicates the fact that the self-sensing microcantilevers approach is beneficial for pathological tests.

Performance Characteristics of Some Small Scale Wind Turbines Fabricated in Tanzania

In this study, a field testing has been carried out to assess the power characteristics of some small scale wind turbines fabricated by one native technician from Tanzania. Two Horizontal Axis Wind Turbines (HAWTs), one with five and other with sixteen blades were installed at a height of 2.4m above the ground. The rotation speed of the rotor blade and wind speed approaching the turbines were measured simultaneously. The data obtained were used to determine how the power coefficient varies as a function of tip speed ratio and also the way in which the output power compares with available power in the wind for each turbine. For the sixteen-bladed wind turbine the maximum value of power coefficient of about 0.14 was found to occur at a tip speed ratio of around 0.65 while for the five bladed, these extreme values were respectively attained at approximately 0.2 and 1.7. The five bladed-wind turbine was found to have a higher power efficiency of about 37.5% which is higher compared to the sixteen bladed wind turbine whose corresponding value was 14.37%. This is what would be expected, as the smaller the number of blades of a wind turbine, the higher the electric power efficiency and vice versa. Some of the main reasons for the low efficiency of these machines may be due to the low aerodynamic efficiency of the turbine or low efficiency of the transmission mechanisms such as gearbox and generator which were not examined in this study. It is recommended that some other researches be done to investigate the power efficiency of such machines from different manufacturers in the country. The manufacturers should also be encouraged to use fewer blades in their designs so as to improve the efficiency and at the same time reduce materials used to fabricate the blades. The power efficiency of the electric generators used in the locally fabricated wind turbines should also be examined.

Exercise and Cognitive Function: Time Course of the Effects

Previous research has indicated a variable effect of exercise on adolescents’ cognitive function. However, comparisons between studies are difficult to make due to differences in: the mode, intensity and duration of exercise employed; the components of cognitive function measured (and the tests used to assess them); and the timing of the cognitive function tests in relation to the exercise. Therefore, the aim of the present study was to assess the time course (10 and 60min post-exercise) of the effects of 15min intermittent exercise on cognitive function in adolescents. 45 adolescents were recruited to participate in the study and completed two main trials (exercise and resting) in a counterbalanced crossover design. Participants completed 15min of intermittent exercise (in cycles of 1 min exercise, 30s rest). A battery of computer based cognitive function tests (Stroop test, Sternberg paradigm and visual search test) were completed 30 min pre- and 10 and 60min post-exercise (to assess attention, working memory and perception respectively).The findings of the present study indicate that on the baseline level of the Stroop test, 10min following exercise response times were slower than at any other time point on either trial (trial by session time interaction, p = 0.0308). However, this slowing of responses also tended to produce enhanced accuracy 10min post-exercise on the baseline level of the Stroop test (trial by session time interaction, p = 0.0780). Similarly, on the complex level of the visual search test there was a slowing of response times 10 min post-exercise (trial by session time interaction, p = 0.0199). However, this was not coupled with an improvement in accuracy (trial by session time interaction, p = 0.2349). The mid-morning bout of exercise did not affect response times or accuracy across the morning on the Sternberg paradigm. In conclusion, the findings of the present study suggest an equivocal effect of exercise on adolescents' cognitive function. The mid-morning bout of exercise appears to cause a speed-accuracy trade off immediately following exercise on the Stroop test (participants become slower but more accurate), whilst slowing response times on the visual search test and having no effect on performance on the Sternberg paradigm. Furthermore, this work highlights the importance of the timing of the cognitive function tests relative to the exercise and the components of cognitive function examined in future studies. 

Family and Young Learners´ Scholastic Success

This contribution examines the relationship between the family environment and the level of young pupils’ scholastic success. It comments on the partial results of a research probe carried out in the year 2012 on a sample of 412 Czech Republic primary school pupils of the fourth, fifth and sixths forms within the Project IGA 43 201 15 0004 01. The key links of this project were monitored in relation to the highest education level achieved by the learners´ parents, as well as to the type of family it is (in particular its ability to function), to component factors specific to the family climate (their willingness to share information, communication, parental control) and, finally, to the number of children in the family as an important socialization constituent.

Hospital-Pharmacy Management System: A UAE Case Study

Large patients’ queues at pharmacies and hospitals are a problem that faces the supposedly smooth and healthy environment in United Arab Emirates. As this sometimes leads to dissatisfaction from visiting patients, we tried to solve this problem with additional beneficial functions by developing the Hospital-Pharmacy Management System. The primary purpose of this research is to develop a system that joins the databases of a hospital and a pharmacy together for a better integrated system that provides a better coherent working environment. Three methods are used to design the system. These methods are detailed literature review, an extensive feasibility study and surveys for doctors, hospital IT managers and End-users. Interviews and surveys with related stakeholders were done to depict system’s requirements; design and prototype. The prototype illustrates system’s features and its client and server architecture. The system has a mobile application for visiting patients to, mainly, keep track of their prescriptions and access to their personal information. The server side allows doctors to submit the prescriptions online to pharmacists who will process them. This system is expected to reduce the long waiting queues of patients and increase their satisfaction while also reducing doctors and pharmacists’ stress and facilitating their work. It will be deployed to users of Android devices only. This limitation will be resolved, as one of main future enhancements, once the system finds acceptance from hospitals and pharmacies in United Arab Emirates.

Cold Analysis for Dispersion, Attenuation and RF Efficiency Characteristics of a Gyrotron Cavity

In the present paper, a gyrotron cavity is analyzed in the absence of electron beam for dispersion, attenuation and RF efficiency. For all these characteristics, azimuthally symmetric TE0n modes have been considered. The attenuation characteristics for TE0n modes indicated decrease in attenuation constant as the frequency is increased. Interestingly, the lowest order TE01 mode resulted in lowest attenuation. Further, three different cavity wall materials have been selected for attenuation characteristics. The cavity made of material with higher conductivity resulted in lower attenuation. The effect of material electrical conductivity on the RF efficiency has also been observed and has been found that the RF efficiency rapidly decreases as the electrical conductivity of the cavity material decreases. The RF efficiency rapidly decreases with increasing diffractive quality factor. The ohmic loss variation as a function of frequency of operation for three different cavities made of copper, aluminum and nickel has been observed. The ohmic losses are lowest for the copper cavity and hence the highest RF efficiency.

A Homogenisation Procedure for the Free Vibration Analysis of Functionally Graded Beams at Large Vibration Amplitudes

The purpose of the present paper is to show that the problem of geometrically nonlinear free vibrations of functionally graded beams (FGB) with immovable ends can be reduced to that of isotropic homogeneous beams with effective bending stiffness and axial stiffness parameters by using an homogenization procedure. The material properties of the functionally graded composites examined are assumed to be graded in the thickness direction and estimated through the rule of mixture. The theoretical model is based on the Euler-Bernouilli beam theory and the Von Kármán geometrical nonlinearity assumptions. Hamilton’s principle is applied and a multimode approach is derived to calculate the fundamental nonlinear frequency parameters, which are found to be in a good agreement with the published results. The non-dimensional curvatures associated to the nonlinear fundamental mode are also given for various vibration amplitudes in the case of clamped-clamped FGB.

Supporting Technology Transfer with Communities and Social Software Solutions

In order to bridge the gap between research and industry, promoting technology and knowledge transfer becomes increasingly important. Especially small- and medium-sized enterprises, having only little R&D resources themselves, depend on external technology development activities for remaining innovative. Academia research on the other hand needs potential industrial partners, who are capable and willing to commercialize their technologies as most public funding programs require some sort of technology transfer or dissemination activities. Modern web technologies offer more and more “social” functionalities and open up new ways of user interaction. In the past years several technology transfer platforms were developed, making use of modern web technologies in order to enable and support technology transfer. In this paper we report on the results of a state-of-the art analyses of existing technology transfer platforms, point out their advantages and deficits and give a perspective to the development of an improved technology transfer platform.

Geometrically Non-Linear Axisymmetric Free Vibrations of Thin Isotropic Annular Plates

The effects of large vibration amplitudes on the first axisymetric mode shape of thin isotropic annular plates having both edges clamped are examined in this paper. The theoretical model based on Hamilton’s principle and spectral analysis by using a basis of Bessel’s functions is adapted اhere to the case of annular plates. The model effectively reduces the large amplitude free vibration problem to the solution of a set of non-linear algebraic equations. The governing non-linear eigenvalue problem has been linearised in the neighborhood of each resonance and a new one-step iterative technique has been proposed as a simple alternative method of solution to determine the basic function contributions to the non-linear mode shape considered. Numerical results are given for the first non-linear mode shape for a wide range of vibration amplitudes. For each value of the vibration amplitude considered, the corresponding contributions of the basic functions defining the non-linear transverse displacement function and the associated non-linear frequency, the membrane and bending stress distributions are given. By comparison with the iterative method of solution, it was found that the present procedure is efficient for a wide range of vibration amplitudes, up to at least 1.8 times the plate thickness,

A Decision Matrix for the Evaluation of Triplestores for Use in a Virtual Research Environment

The Tropical Data Hub (TDH) is a virtual research environment that provides researchers with an e-research infrastructure to congregate significant tropical data sets for data reuse, integration, searching, and correlation. However, researchers often require data and metadata synthesis across disciplines for cross-domain analyses and knowledge discovery. A triplestore offers a semantic layer to achieve a more intelligent method of search to support the synthesis requirements by automating latent linkages in the data and metadata. Presently, the benchmarks to aid the decision of which triplestore is best suited for use in an application environment like the TDH are limited to performance. This paper describes a new evaluation tool developed to analyze both features and performance. The tool comprises a weighted decision matrix to evaluate the interoperability, functionality, performance, and support availability of a range of integrated and native triplestores to rank them according to requirements of the TDH.

Q-Learning with Eligibility Traces to Solve Non-Convex Economic Dispatch Problems

Economic Dispatch is one of the most important power system management tools. It is used to allocate an amount of power generation to the generating units to meet the load demand. The Economic Dispatch problem is a large scale nonlinear constrained optimization problem. In general, heuristic optimization techniques are used to solve non-convex Economic Dispatch problem. In this paper, ideas from Reinforcement Learning are proposed to solve the non-convex Economic Dispatch problem. Q-Learning is a reinforcement learning techniques where each generating unit learn the optimal schedule of the generated power that minimizes the generation cost function. The eligibility traces are used to speed up the Q-Learning process. Q-Learning with eligibility traces is used to solve Economic Dispatch problems with valve point loading effect, multiple fuel options, and power transmission losses.

Can EEG Test Helps in Identifying Brain Tumor?

Brain tumor is inherently serious and life-threatening disease. Brain tumor builds the intracranial pressure in the brain, by shifting the brain or pushing against the skull, and also damaging nerves and healthy brain tissues. This intracranial pressure affects and interferes with normal brain functionality, which results in generation of abnormal electrical activities from brain. With recent development in the medical engineering and instruments, EEG instruments are able to record the brain electric activities with high accuracy, which establishes EEG as a primary tool for diagnosing the brain abnormalities. Research scholars and general physicians, often face difficulty in understanding EEG patterns. This paper presents the EEG patterns associated with brain tumor by combing medicine theory and neurologist experience. Paper also explains the pros-cons of the EEG based brain tumor identification.

Examination of the Effect of Air Viscosity on Narrow Acoustic Tubes Using FEM Involving Complex Effective Density and Complex Bulk Modulus

Earphones and headphones, which are compact electro-acoustic transducers, tend to have a lot of acoustic absorption materials and porous materials known as dampers, which often have a large number of extremely small holes and narrow slits to inhibit the resonance of the vibrating system, because the air viscosity significantly affects the acoustic characteristics in such acoustic paths. In order to perform simulations using the finite element method (FEM), it is necessary to be aware of material characteristics such as the impedance and propagation constants of sound absorbing materials and porous materials. The transfer function is widely known as a measurement method for an acoustic tube with such physical properties, but literature describing the measurements at the upper limits of the audible range is yet to be found. The acoustic tube, which is a measurement instrument, must be made narrow, and the distance between the two sets of microphones must be shortened in order to take measurements of acoustic characteristics at higher frequencies. When such a tube is made narrow, however, the characteristic impedance has been observed to become lower than the impedance of air. This paper considers the cause of this phenomenon to be the effect of the air viscosity and describes an FEM analysis of an acoustic tube considering air viscosity to compare to the theoretical formula by including the effect of air viscosity in the theoretical formula for an acoustic tube.

A Computational Fluid Dynamic Model of Human Sniffing

The objective of this paper is to develop a computational model of human nasal cavity from computed tomography (CT) scans using MIMICS software. Computational fluid dynamic techniques were employed to understand nasal airflow. Gambit and Fluent software was used to perform CFD simulation. Velocity profiles, iteration plots, pressure distribution, streamline and pathline patterns for steady, laminar airflow inside the human nasal cavity of healthy and also infected persons are presented in detail. The implications for olfaction are visualized. Results are validated with the available numerical and experimental data. The graphs reveal that airflow varies with different anatomical nasal structures and only fraction of the inspired air reaches the olfactory region. The Deviations in the results suggest that the treatment of infected volunteers will improve the olfactory function.

Optimization of Electrospinning Parameter by Employing Genetic Algorithm in order to Produce Desired Nanofiber Diameter

A numerical simulation of optimization all of electrospinning processing parameters to obtain smallest nanofiber diameter have been performed by employing genetic algorithm (GA). Fitness function in genetic algorithm methods, which was different for each parameter, was determined by simulation approach based on the Reneker’s model. Moreover, others genetic algorithm parameter, namely length of population, crossover and mutation were applied to get the optimum electrospinning processing parameters. In addition, minimum fiber diameter, 32 nm, was achieved from a simulation by applied the optimum parameters of electrospinning. This finding may be useful for process control and prediction of electrospun fiber production. In this paper, it is also compared between predicted parameters with some experimental results.

Roughness and Hardness of 60/40 Cu-Zn Alloy

The functional performance of machined components, often, depends on surface topography, hardness, nature of stress and strain induced on the surface, etc. Invariably, surfaces of metallic components obtained by turning, milling, etc., consist of irregularities such as machining marks are responsible for the above. Surface finishing/coating processes used to produce improved surface quality/textures are classified as chip-removal and chip-less processes. Burnishing is chip-less cold working process carried out to improve surface finish, hardness and resistance to fatigue and corrosion; not obtainable by other surface coating and surface treatment processes. It is a very simple, but effective method which improves surface characteristics and is reported to introduce compressive stresses. Of late, considerable attention is paid to post-machining, finishing operations, such as burnishing. During burnishing the micro-irregularities start to deform plastically, initially the crests are gradually flattened and zones of reduced deformation are formed. When all the crests are deformed, the valleys between the micro-irregularities start moving in the direction of the newly formed surface. The grain structure is then condensed, producing a smoother and harder surface with superior load-carrying and wear-resistant capabilities. Burnishing can be performed on a lathe with a highly polished ball or roller type tool which is traversed under force over a rotating/stationary work piece. Often, several passes are used to obtain the work piece surface with the desired finish and hardness. This paper presents the findings of an experimental investigation on the effect of ball burnishing parameters such as, burnishing speed, feed, force and number of passes; on surface roughness (Ra) and micro-hardness (Hv) of a 60/40 copper/zinc alloy, using a 2-level fractional factorial design of experiments (DoE). Mathematical models were developed to predict surface roughness and hardness generated by burnishing in terms of the above process parameters. A ball-type tool, designed and constructed from a high chrome steel material (HRC=63 and Ra=0.012 µm), was used for burnishing of fine-turned cylindrical bars (0.68-0.78µm and 145Hv). They are given by,   Ra= 0.305-0.005X1 - 0.0175X2 + 0.0525X4 + 0.0125X1X4 -0.02X2X4 - 0.0375X3X4   Hv=160.625 -2.37 5X1 + 5.125X2 + 1.875X3 + 4.375X4 - 1.625X1X4 + 4.375X2X4 - 2.375X3X4   High surface microhardness (175HV) was obtained at 400rpm, 2passes, 0.05mm/rev and 15kgf., and high surface finish (0.20µm) was achieved at 30kgf, 0.1mm/rev, 112rpm and single pass. In other words, surface finish improved by 350% and microhardness improved by 21% compared to as machined conditions.

Lime-Pozzolan Plasters with Enhanced Thermal Capacity

A new type of lightweight plaster with the thermal capacity enhanced by PCM (Phase Change Material) addition is analyzed. The basic physical characteristics, namely the bulk density, matrix density, total open porosity, and pore size distribution are measured at first. For description of mechanical properties, compressive strength measurements are done. The thermal properties are characterized by transient impulse techniques as well as by DSC analysis that enables determination of the specific heat capacity as a function of temperature. The resistivity against the liquid water ingress is described by water absorption coefficient measurement. The experimental results indicate a good capability of the designed plaster to moderate effectively the interior climate of buildings.

Prototype of Business Directory for Micro, Small and Medium Enterprises Using Google Maps API and Multimedia

This paper explain about prototype of a business directory for micro-scale businesses, small and medium enterprises (SMEs), the third phase of the research. The third phase is the phase of software development based on the model of SME business directory that had been developed, to create prototype software SME business directory. In the fourth phase, namely the implementation, these units have been developed are tested to obtain input from potential users. The fifth phase is the testing phase to determine the strengths and weaknesses of software has been developed. The result of this phase is the software in the form of on-line (web based) and multimedia-based. Business Directory, if implemented will facilitate and optimize the access of SMEs to ease supplier access to marketing. Business Directory will be equipped with the power of geocoding, so each location can be easily viewed SMEs on the map. The map will be constructed by using the functionality of a web-based Google Maps API. The information presented in the form of multimedia that can be more interesting and interactive. Methodology used to achieve the goal: observation, interviews, modeling and classifying business directory for SMEs. 

Web Application for University Internship Program Management

This paper discusses a software application to aid in the smooth functioning of a university internship program, including a student, faculty and an administration module. The software can also calculate the most apt combination of students to stations and allocate them respectively.

Pulse Oximeter Concept for Vascular Occlusion Test

Microcirculatory dysfunction is very common in sepsis and may results in organ failure and increased risk of death. Analyzing oxygen utilization can potentially assess microcirculation function of an individual. In this study, a modified pulse oximeter is used to extract information signals due to absorption of red (R) and infrared (IR) light. IR and R signal are related to the overall blood volume and reduced hemoglobin, respectively. Differences between these two signals thus represent the amount of oxygenated hemoglobin. Avascular occlusion test has been conducted on healthy individuals to validate the pulse oximeter concept. In this test, both R and IR signals rapidly changed according to the occlusion process. The pulse oximeter concept presented is capable of extracting valuable information to assess microcirculation condition. Implementing this concept on ICU patients has the potential to aid sepsis diagnosis and provide more accurate tracking of patient state and sepsis status.