Abstract: MicroRNAs are an important class of gene expression
regulators that are involved in many biological processes including
embryogenesis. miR-125b is a conserved microRNA that is enriched
in the nervous system. We have previously reported the function of
miR-125b in neuronal differentiation of human cell lines. We also
discovered the function of miR-125b in regulating p53 in human and
zebrafish. Here we further characterize the brain defects in zebrafish
embryos injected with morpholinos against miR-125b. Our data
confirm the essential role of miR-125b in brain morphogenesis
particularly in maintaining the balance between proliferation, cell
death and differentiation. We identified lunatic fringe (lfng) as an
additional target of miR-125b in human and zebrafish and suggest
that lfng may mediate the function of miR-125b in neurogenesis.
Together, this report reveals new insights into the function of miR-
125b during neural development of zebrafish.
Abstract: The present paper deals with problems related to the
possibilities to use fractal systems to solve some important scientific
and practical problems connected with filtering and separation of
aqueous phases from organic ones. For this purpose a special
separator have been designed. The reactor was filled with a porous
material with fractal dimension, which is an integral part of the set
for filtration and separation of emulsions. As a model emulsion
hexadecan mixture with water in equal quantities (1:1) was used. We
examined the hydrodynamics of the separation of the emulsion at
different rates of submission of the entrance of the reactor.
Abstract: From the perspective of system of systems (SoS) and
emergent behaviors, this paper describes large scale application
software systems, and proposes framework methods to further depict
systems- functional and non-functional characteristics. Besides, this
paper also specifically discusses some functional frameworks. In the
end, the framework-s applications in system disintegrations, system
architecture and stable intermediate forms are additionally dealt with
in this in building, deployment and maintenance of large scale
software applications.
Abstract: Text categorization - the assignment of natural language documents to one or more predefined categories based on their semantic content - is an important component in many information organization and management tasks. Performance of neural networks learning is known to be sensitive to the initial weights and architecture. This paper discusses the use multilayer neural network initialization with decision tree classifier for improving text categorization accuracy. An adaptation of the algorithm is proposed in which a decision tree from root node until a final leave is used for initialization of multilayer neural network. The experimental evaluation demonstrates this approach provides better classification accuracy with Reuters-21578 corpus, one of the standard benchmarks for text categorization tasks. We present results comparing the accuracy of this approach with multilayer neural network initialized with traditional random method and decision tree classifiers.
Abstract: Synthetic aperture radar (SAR) imaging usually
requires echo data collected continuously pulse by pulse with certain
bandwidth. However in real situation, data collection or part of signal
spectrum can be interrupted due to various reasons, i.e. there will be
gaps in spatial spectrum. In this case we need to find ways to fill out
the resulted gaps and get image with defined resolution. In this paper
we introduce our work on how to apply iterative spatially variant
apodization (Super-SVA) technique to extrapolate the spatial
spectrum in both azimuthal and range directions so as to fill out the
gaps and get correct radar image.
Abstract: The paper deals with the analysis of the dynamic
response of footbridges under human - induced dynamic loads.
This is a frequently occurring and often dominant load for
footbridges as it stems from the very purpose of a footbridge - to
convey pedestrian. Due to the emergence of new materials and
advanced engineering technology, slender footbridges are
increasingly becoming popular to satisfy the modern transportation
needs and the aesthetical requirements of the society. These
structures however are always lively with low stiffness, low mass,
low damping and low natural frequencies. As a consequence, they are
prone to vibration induced by human activities and can suffer severe
vibration serviceability problems, particularly in the lateral direction.
Pedestrian bridges are designed according to first and second limit
states, these are the criteria involved in response to static design load.
However, it is necessary to assess the dynamic response of bridge
design load on pedestrians and assess it impact on the comfort of the
user movement. Usually the load is considered a person or a small
group which can be assumed in perfect motion synchronization.
Already one person or small group can excite significant vibration of
the deck. In order to calculate the dynamic response to the movement
of people, designer needs available and suitable computational model
and criteria. For the calculation program ANSYS based on finite
element method was used.
Abstract: The wireless mesh networks (WMNs) are emerging technology in wireless networking as they can serve large scale high speed internet access. Due to its wireless multi-hop feature, wireless mesh network is prone to suffer from many attacks, such as denial of service attack (DoS). We consider a special case of DoS attack which is selective forwarding attack (a.k.a. gray hole attack). In such attack, a misbehaving mesh router selectively drops the packets it receives rom its predecessor mesh router. It is very hard to detect that packet loss is due to medium access collision, bad channel quality or because of selective forwarding attack. In this paper, we present a review of detection algorithms of selective forwarding attack and discuss their advantage & disadvantage. Finally we conclude this paper with open research issues and challenges.
Abstract: Practices of food sharing as part of the brotherhood and hospitality interpretation have been essential part of the Kazakh ethnic culture since early times. Dialogue in time and space between Kazakhs through differences in food interpretation among the ethnic repatriates may become a link connecting them and platform for stable relations with the host society or serious barrier on the way of their integration in the Kazakhstani society. The article elucidates by the field materials how some aspects of food culture differences among ethnic Kazakhs living abroad (XUAR of China) and ethnic repatriates in Kazakhstan may influence their integration path.
Abstract: The optimal design of PI controller for Automatic Generation Control in two area is presented in this paper. The concept of Dual mode control is applied in the PI controller, such that the proportional mode is made active when the rate of change of the error is sufficiently larger than a specified limit otherwise switched to the integral mode. A digital simulation is used in conjunction with the Hooke-Jeeve’s optimization technique to determine the optimum parameters (individual gain of proportional and integral controller) of the PI controller. Integrated Square of the Error (ISE), Integrated Time multiplied by Absolute Error(ITAE) , and Integrated Absolute Error(IAE) performance indices are considered to measure the appropriateness of the designed controller. The proposed controller are tested for a two area single nonreheat thermal system considering the practical aspect of the problem such as Deadband and Generation Rate Constraint(GRC). Simulation results show that dual mode with optimized values of the gains improved the control performance than the commonly used Variable Structure .
Abstract: Multiple-Input-Multiple-Output (MIMO) is one of the most important communication techniques that allow wireless systems to achieve higher data rate. To overcome the practical difficulties in implementing Dirty Paper Coding (DPC), various suboptimal MIMO Broadcast (MIMO-BC) scheduling algorithms are employed which choose the best set of users among all the users. In this paper we discuss such a sub-optimal MIMO-BC scheduling algorithm which employs antenna selection at the receiver side. The channels for the users considered here are not Identical and Independent Distributed (IID) so that users at the receiver side do not get equal opportunity for communication. So we introduce a method of applying weights to channels of the users which are not IID in such a way that each of the users gets equal opportunity for communication. The effect of weights on overall sum-rate achieved by the system has been investigated and presented.
Abstract: This article discusses the prospects of participation of
the Republic of Kazakhstan in Hague Conference on Private
International Law on the unification of collision law in the
international trade.
The article analyzes some conventions on international trade. The
appropriate conclusions based on the opinions of scientists and
experts in this field have been made. First, all issues presented in the
form of gaps or spaces in conventions should be the subject to direct
negotiations in the course of the activities of Hague Conference, and
have a comprehensive feature, be transparent and taken under
simplified procedure.
Secondly, one should not underestimate the value of conventions
that do not become active due to various reasons and having a
positive impact on the development and improvement of national
legislation and practice in the field of private international law.
Thirdly, Kazakhstan has to reconsider its attitude to Hague
Conference, having become its full member and aiming at providing
constructive and fruitful cooperation with both the organization itself
and its member states.
Abstract: The authors present an optimization algorithm for order reduction and its application for the determination of the relative mapping errors of linear time invariant dynamic systems by the simplified models. These relative mapping errors are expressed by means of the relative integral square error criterion, which are determined for both unit step and impulse inputs. The reduction algorithm is based on minimization of the integral square error by particle swarm optimization technique pertaining to a unit step input. The algorithm is simple and computer oriented. It is shown that the algorithm has several advantages, e.g. the reduced order models retain the steady-state value and stability of the original system. Two numerical examples are solved to illustrate the superiority of the algorithm over some existing methods.
Abstract: Face authentication for access control is a face
membership authentication which passes the person of the incoming
face if he turns out to be one of an enrolled person based on face
recognition or rejects if not. Face membership authentication belongs
to the two class classification problem where SVM(Support Vector
Machine) has been successfully applied and shows better performance
compared to the conventional threshold-based classification. However,
most of previous SVMs have been trained using image feature vectors
extracted from face images of each class member(enrolled
class/unenrolled class) so that they are not robust to variations in
illuminations, poses, and facial expressions and much affected by
changes in member configuration of the enrolled class
In this paper, we propose an effective face membership
authentication method based on SVM using class discriminating
features which represent an incoming face image-s associability with
each class distinctively. These class discriminating features are weakly
related with image features so that they are less affected by variations
in illuminations, poses and facial expression.
Through experiments, it is shown that the proposed face
membership authentication method performs better than the threshold
rule-based or the conventional SVM-based authentication methods and
is relatively less affected by changes in member size and membership.
Abstract: As the Social network game(SNG) is rising
dramatically worldwide, an interesting aspect has appeared in the
demographic analysis. That is the ratio of the game users by gender.
Although the ratio of male and female users in online game was
60:40% previously, the ratio of male and female users in SNG stood at
47:53% which shows that the ratio of female users is higher than that
of male users. Here, it should be noted that 35% in those 53% female
users are the first-time users of game. This fact suggests that women
who were not interested in game previously has taken an interest in
SNG. Notwithstanding this issue, there have been little studies on the
female users of SNG although there are many studies that analyzed the
tendency of female users- online game play. This study conducted the
analyzed how the game-playing tendency of SNG gamers was
manifested in the game by gender. For that, this study will identify the
tendency of SNG users by gender based on the preceding studies that
analyzed the online game users by gender. The subject of this study
was confined to the farm and urban construction simulation games
which were offered based on the mobile application platform.
Regarding the methodology of study, the first focus group
interview(FGI) was conducted with the male and female users who
had played games on Social network service(SNS) until recently. Later,
the second one-on-one in-depth interview was conducted to gain an
insight into the psychological state of the subjects.
Abstract: This article describes a Web pages automatic filtering system. It is an open and dynamic system based on multi agents architecture. This system is built up by a set of agents having each a quite precise filtering task of to carry out (filtering process broken up into several elementary treatments working each one a partial solution). New criteria can be added to the system without stopping its execution or modifying its environment. We want to show applicability and adaptability of the multi-agents approach to the networks information automatic filtering. In practice, most of existing filtering systems are based on modular conception approaches which are limited to centralized applications which role is to resolve static data flow problems. Web pages filtering systems are characterized by a data flow which varies dynamically.
Abstract: The purpose of this paper is to propose an integrated
consumer health informatics utilization framework that can be used
to gauge the online health information needs and usage patterns
among Malaysian women. The proposed framework was developed
based on four different theories/models: Use and Gratification
Theory, Technology Acceptance 3 Model, Health Belief Model, and
Multi-level Model of Information Seeking. The relevant constructs
and research hypotheses are also presented in this paper. The
framework will be tested in order for it to be used successfully to
identify Malaysian women-s preferences of online health information
resources and health information seeking activities.
Abstract: In this paper we use classical linear stability theory
to investigate the effects of uniform internal heat generation on the
onset of Marangoni convection in a horizontal layer of fluid heated
from below. We use a analytical technique to obtain the close form
analytical expression for the onset of Marangoni convection when
the lower boundary is conducting with free-slip condition. We show
that the effect of increasing the internal heat generation is always to
destabilize the layer.
Abstract: In this article, we are going to do a study that consist in the configuration of a link between an earth station to broadcast multimedia service and a user of this service via a geostationary satellite in Ka- band and the set up of the different components of this link and then to make the calculation of the link budget for this system. The application carried out in this work, allows us to calculate the link budget in both directions: the uplink and downlink, as well as all parameters used in the calculation and the development of a link budget. Finally, we will try to verify using the application developed the feasibility of implementation of this system.
Abstract: Research and development R&D work involves
enormous amount of work that has to do with data measurement and
collection. This process evolves as new information is fed, new
technologies are utilized, and eventually new knowledge is created
by the stakeholders i.e., researchers, clients, and end-users. When
new knowledge is created, procedures of R&D work should evolve
and produce better results within improved research skills and
improved methods of data measurements and collection. This
measurement improvement should then be benchmarked against a
metric that should be developed at the organization. In this paper, we
are suggesting a conceptual metric for R&D work performance
improvement (PI) at the Kuwait Institute for Scientific Research
(KISR). This PI is to be measured against a set of variables in the
suggested metric, which are more closely correlated to organizational
output, as opposed to organizational norms. The paper also mentions
and discusses knowledge creation and management as an addedvalue
to R&D work and measurement improvement. The research
methodology followed in this work is qualitative in nature, based on
a survey that was distributed to researchers and interviews held with
senior researchers at KISR. Research and analyses in this paper also
include looking at and analyzing KISR-s literature.
Abstract: Gluconic acid is one of interesting chemical products
in industries such as detergents, leather, photographic, textile, and
especially in food and pharmaceutical industries. Fermentation is an
advantageous process to produce gluconic acid. Mathematical
modeling is important in the design and operation of fermentation
process. In fact, kinetic data must be available for modeling. The
kinetic parameters of gluconic acid production by Aspergillus niger
in batch culture was studied in this research at initial substrate
concentration of 150, 200 and 250 g/l. The kinetic models used were
logistic equation for growth, Luedeking-Piret equation for gluconic
acid formation, and Luedeking-Piret-like equation for glucose
consumption. The Kinetic parameters in the model were obtained by
minimizing non linear least squares curve fitting.