Abstract: Skin aging is a slow multifactorial process influenced
by both internal as well as external factors. Ultra-violet radiations
(UV), diet, smoking and personal habits are the most common
environmental factors that affect skin aging. Fat contents and fibrous
proteins as collagen and elastin are core internal structural
components. The direct influence of UV on elastin integrity and
health is central on aging of skin especially by time. The deposition
of abnormal elastic material is a major marker in a photo-aged skin.
Searching for compounds that may protect against cutaneous photodamage
is exceedingly valued. Retinoids and alpha hydroxy acids
have been endorsed by some researchers as possible candidates for
protecting and or repairing the effect of UV damaged skin. For
consolidating a better system of anti- and protective effects of such
anti-aging agents, we evaluated the combinatory effects of various
dosages of lactic acid and retinol on the dermal fibroblast’s elastin
levels exposed to UV. The UV exposed cells showed significant
reduction in the elastin levels. A combination of drugs with a higher
concentration of lactic acid (30 -35 mM) and a lower concentration of
retinol (10-15mg/mL) showed to work better in maintaining elastin
concentration in UV exposed cells. We assume this preservation
could be the result of increased tropo-elastin gene expression
stimulated by retinol whereas lactic acid probably repaired the UV
irradiated damage by enhancing the amount and integrity of the
elastin fibers.
Abstract: Humans are social mammals, of the primate order.
Our biology, our behaviour and our pathologies are unique to us. In
our desire to understand, reduce solitary confinement one source of
information is the many reports of social isolation of other social
mammals, especially primates. A behavioural study was conducted in
the department of pharmacology at Indira Gandhi Medical College,
Shimla in Himachalpradesh province in India using white albino
mice. Different behavioural parameters were observed by using open
field, tail suspension, tests for aggressive behaviour and social
interactions and the effect of isolation was studied. The results were
evaluated and the standard statistics were applied. The said study was
done to establish facts that isolation itself impairs social behaviour
and can lead to alcohol dependence as well as related drug
dependence.
Abstract: A well designed and executed Production Planning
and Control (PPC) system is one of the key levers for superior
performance in the current manufacturing set-up. Hence, measuring
the PPC system performance has become a necessity for long term
success. The present study examined PPC related issues which
impact the production capacity and productivity of leather companies
with special focus on Kombolcha Tannery Share Company (KTSC),
Ethiopia. Physical observation, interview, and questionnaire were
used to generate necessary information from the respondents and
reach valid conclusions. Company annual reports were referred and
analyzed to triangulate primary data. Consequently, the study
revealed that KTSC runs below its capacity due to its inefficient PPC
system being in use for which the root causes were identified. The
study thereby conceptualizes a PPC system improvement framework
comprising three pillars viz., management culture, internal capability
and performance measurement together with key considerations in
each case. The study findings enable the company to recognize the
importance of efficient PPC system as a source of competitive
advantage. It also aid managers in evaluating various PPC execution
schemes to enhance productivity.
Abstract: Poly vinyl acetate (PVA)-based titania (TiO2)–carbon
nanotube composite nanofibers (PVA-TCCNs) with various
PVA-to-solvent ratios and PVA-based TiO2 composite nanofibers
(PVA-TN) were synthesized using an electrospinning process,
followed by thermal treatment. The photocatalytic activities of these
nanofibers in the degradation of airborne monocyclic aromatics under
visible-light irradiation were examined. This study focuses on the
application of these photocatalysts to the degradation of the target
compounds at sub-part-per-million indoor air concentrations. The
characteristics of the photocatalysts were examined using scanning
electron microscopy, X-ray diffraction, ultraviolet-visible
spectroscopy, and Fourier-transform infrared spectroscopy. For all the
target compounds, the PVA-TCCNs showed photocatalytic
degradation efficiencies superior to those of the reference PVA-TN.
Specifically, the average photocatalytic degradation efficiencies for
benzene, toluene, ethyl benzene, and o-xylene (BTEX) obtained using
the PVA-TCCNs with a PVA-to-solvent ratio of 0.3 (PVA-TCCN-0.3)
were 11%, 59%, 89%, and 92%, respectively, whereas those observed
using PVA-TNs were 5%, 9%, 28%, and 32%, respectively.
PVA-TCCN-0.3 displayed the highest photocatalytic degradation
efficiency for BTEX, suggesting the presence of an optimal
PVA-to-solvent ratio for the synthesis of PVA-TCCNs. The average
photocatalytic efficiencies for BTEX decreased from 11% to 4%, 59%
to 18%, 89% to 37%, and 92% to 53%, respectively, when the flow
rate was increased from 1.0 to 4.0 L min1. In addition, the average
photocatalytic efficiencies for BTEX increased 11% to ~0%, 59% to
3%, 89% to 7%, and 92% to 13%, respectively, when the input
concentration increased from 0.1 to 1.0 ppm. The prepared
PVA-TCCNs were effective for the purification of airborne aromatics
at indoor concentration levels, particularly when the operating
conditions were optimized.
Abstract: The mixed micellization of adiphenine hydrochloride (ADP) with 1-decyl-3-methylimidazolium chloride (C10mim.Cl), was investigated at different mole fractions and temperatures by surface tension measurements. The synergistic behavior (i.e., non-ideal behavior) for binary mixtures was explained by the deviation of critical micelle concentration (cmc) from ideal critical micelle concentration (cmc*), micellar mole fraction (Xim) from ideal micellar mole fraction (Xiideal), the values of interaction parameter (β) and activity coefficients (fi) (for both mixed micelles and mixed monolayer). The excess free energy (ΔGex) for the ADP- C10mim.Cl binary mixtures explain the stability of mixed micelles in comparison to micelles of pure ADP and C10mim.Cl. Interfacial parameters, i.e., Gibbs surface excess (Гmax), minimum head group area at air/ water
interface (Amin), and free energy of micellization (ΔG0m) were also evaluated for the systems.
Abstract: Carbon Deposits are often occurred inside the
industrial coke oven during coking process. Accumulation of carbon
deposits may cause a big issue, which seriously influences the coking
operation. The carbon is burning off by injecting fresh air through
pipes into coke oven which is an efficient way practically operated in
industries. The burning off carbon deposition in coke oven performed
by Computational Fluid Dynamics (CFD) method has provided an
evaluation of the feasibility study. A three dimensional, transient,
turbulent reacting flow simulation has performed with three different
injecting air flow rate and another kind of injecting configuration. The
result shows that injection higher air flow rate would effectively
reduce the carbon deposits. In the meantime, the opened charging
holes would suck extra oxygen from atmosphere to participate in
reactions. In term of coke oven operating limits, the wall temperatures
are monitored to prevent over-heating of the adiabatic walls during
burn-off process.
Abstract: The objective of this study was to evaluate the
physical and chemical characteristics of Serra da Estrela cheese and
compare these results with those of the sensory analysis. For the
study were taken six samples of Serra da Estrela cheese produced
with 6 different ecotypes of thistle in a dairy situated in Penalva do
Castelo. The chemical properties evaluated were moisture content,
protein, fat, ash, chloride and pH; the physical properties studied
were color and texture; and finally a sensory evaluation was
undertaken. The results showed moisture varying in the range 40-
48%, protein in the range 15-20%, fat between 41-45%, ash between
3.9-5.0% and chlorides varying from 1.2 to 3.0%. The pH varied
from 4.8 to 5.4. The textural properties revealed that the crust
hardness is relatively low (maximum 7.3 N), although greater than
flesh firmness (maximum 1.7 N), and also that these cheeses are in
fact soft paste type, with measurable stickiness and intense
adhesiveness. The color analysis showed that the crust is relatively
light (L* over 50), and with a predominant yellow coloration (b*
around 20 or over) although with a slight greenish tone (a* negative).
The results of the sensory analysis did not show great variability for
most of the attributes measured, although some differences were
found in attributes such as crust thickness, crust uniformity, and
creamy flesh.
Abstract: Emissions of atmospheric pollutants from ships and
harbour activities are a growing concern at international level given
their potential impacts on air quality and climate. These close-to-land
emissions have potential impact on local communities in terms of air
quality and health. Recent studies show that the impact of maritime
traffic to atmospheric particulate matter concentrations in several
coastal urban areas is comparable with the impact of road traffic of a
medium size town. However, several different approaches have been
used for these estimates making difficult a direct comparison of
results. In this work, an integrated approach based on emission
inventories and dedicated measurement campaigns has been applied
to give a comparable estimate of the impact of maritime traffic to
PM2.5 and particle number concentrations in three major harbours of
the Adriatic/Ionian Seas. The influences of local meteorology and of
the logistic layout of the harbours are discussed.
Abstract: Epidermal Growth Factor (EGF, Mw=6,045) has been
reported to have high efficiency of wound repair and anti-wrinkle
effect. However, the half-life of EGF in the body is too short to exert
the biological activity effectively when applied in free form. Growth
Factors can be stabilized by immobilization with carbohydrates from
thermal and proteolytic degradation. Low molecular weight chitosan
(LMCS) and its derivate prepared by hydrogen peroxide has high
solubility. LM6A6DC was successfully prepared as a reactive
carbohydrate for the stabilization of EGF by the reactions of LMCS
with alkalization, tosylation, azidation and reduction. The structure of
LM6A6DC was confirmed by FT-IR, 1H NMR and elementary
analysis. For enhancing the stability of free EGF, EGF was attached
with LM6A6DC by using water-soluble carbodiimide.
EGF-LM6A6DC conjugates did not show any cytotoxicity on the
Normal Human Dermal Fibroblast (NHDF) 3T3 proliferation at least
under 100 μg/ml. In the result, it was considered that LM6A6DC is
suitable to immobilize of growth factor.
Abstract: This paper examines international marketing in
business practice of Czech exporting small and medium-sized
enterprises (SMEs) with regard to the strategic perspectives.
Research was focused on Czech exporting SMEs from Moravian-
Silesia region and their behavior on international markets. For
purpose of collecting data, a questionnaire was given to 262 SMEs
involved in international business. Statistics utilized in this research
included frequency, mean, percentage, and chi-square test. Data were
analyzed by Statistical Package for the Social Sciences software. The
research analysis disclosed that there is certain space for
improvement in strategic marketing especially in a marketing
research, perception of cultural and social differences, product
adaptation and usage of marketing communication tools.
Abstract: Diminished antioxidant defense or increased
production of reactive oxygen species in the biological system can
result in oxidative stress which may lead to various
neurodegenerative diseases including Alzheimer’s disease (AD).
Microglial activation also contributes to the progression of AD by
producing several proinflammatory cytokines, nitric oxide (NO) and
prostaglandin E2 (PGE2). Oxidative stress and inflammation have
been reported to be possible pathophysiological mechanisms
underlying AD. In addition, the cholinergic hypothesis postulates that
memory impairment in patient with AD is also associated with the
deficit of cholinergic function in the brain. Although a number of
drugs have been approved for the treatment of AD, most of these
synthetic drugs have diverse side effects and yield relatively modest
benefits. Marine algae have great potential in pharmaceutical and
biomedical applications as they are valuable sources of bioactive
properties such as anticoagulation, antimicrobial, antioxidative,
anticancer and anti-inflammatory. Hence, this study aimed to provide
an overview of the properties of Malaysian seaweeds (Padina
australis, Sargassum polycystum and Caulerpa racemosa) in
inhibiting oxidative stress, neuroinflammation and cholinesterase
enzymes. These seaweeds significantly exhibited potent DPPH and
moderate superoxide anion radical scavenging ability (P
Abstract: Unmanned aircraft systems (UAS) are playing
increasingly prominent roles in defense programs and defense
strategies around the world. Technology advancements have
enabled the development of it to do many excellent jobs as
reconnaissance, surveillance, battle fighters, and communications
relays. Simulating a small unmanned aerial vehicle (SUAV)
dynamics and analyzing its behavior at the preflight stage is too
important and more efficient. The first step in the UAV design is
the mathematical modeling of the nonlinear equations of motion. .
In this paper, a survey with a standard method to obtain the full
non-linear equations of motion is utilized, and then the
linearization of the equations according to a steady state flight
condition (trimming) is derived. This modeling technique is
applied to an Ultrastick-25e fixed wing UAV to obtain the valued
linear longitudinal and lateral models. At the end the model is
checked by matching between the behavior of the states of the nonlinear
UAV and the resulted linear model with doublet at the
control surfaces.
Abstract: A nanocrystalline thin film of ZnSe was successfully
electrodeposited on copper substrate using a non-aqueous solution
and subsequently annealed in air at 400°C. XRD analysis indicates
the polycrystalline deposit of (111) plane in both the cases. The
sharpness of the peak increases due to annealing of the film and
average grain size increases to 20 nm to 27nm. SEM photograph
indicate that grains are uniform and densely distributed over the
surface. Annealing increases the average grain size by 20%. The EDS
spectroscopy shows the ratio of Zn & Se is 1.1 in case of annealed
film. AFM analysis indicates the average roughness of the film
reduces from 181nm to 165nm due to annealing of the film. The
bandgap also decreases from 2.71eV to 2.62eV.
Abstract: The main objective of aircraft aerodynamics is to
enhance the aerodynamic characteristics and maneuverability of the
aircraft. This enhancement includes the reduction in drag and stall
phenomenon. The airfoil which contains dimples will have
comparatively less drag than the plain airfoil. Introducing dimples on
the aircraft wing will create turbulence by creating vortices which
delays the boundary layer separation resulting in decrease of pressure
drag and also increase in the angle of stall. In addition, wake
reduction leads to reduction in acoustic emission. The overall
objective of this paper is to improve the aircraft maneuverability by
delaying the flow separation point at stall and thereby reducing the
drag by applying the dimple effect over the aircraft wing. This project
includes both computational and experimental analysis of dimple
effect on aircraft wing, using NACA 0018 airfoil. Dimple shapes of
Semi-sphere, hexagon, cylinder, square are selected for the analysis;
airfoil is tested under the inlet velocity of 30m/s and 60m/s at
different angle of attack (5˚, 10˚, 15˚, 20˚, and 25˚). This analysis
favors the dimple effect by increasing L/D ratio and thereby
providing the maximum aerodynamic efficiency, which provides the
enhanced performance for the aircraft.
Abstract: There has been a significant decline in active travel
and a massive increase in the use of car dependent travel in many
countries during the past two decades. Evidential risks for people’s
physical and mental health problems are correlated with this
increased use of motorized travel. These health related problems
range from overweight and obesity to increased air pollution. In
response to these rising concerns health professionals, traffic planers,
local authorities and others have introduced a variety of initiatives to
counterbalance the dominance of cars for daily journeys.
However, the nature of travel behavior change interventions,
which aim to reduce car use, are very complex and challenging
regarding their interactions with human behavior. To change travel
behavior at least two aspects have to be taken into consideration.
First, how to alter attitudes and perceptions toward the sustainable
and healthy modes of travel, in competition with experiences of
private car use. And second, how to make these behavior change
processes irreversible and sustainable. There are no comprehensive
models available to guide policy interventions to increase the level of
success of travel behavior change interventions across both these
dimensions.
A comprehensive theoretical framework is required in the effort to
optimize how to facilitate and guide the processes of data collection
and analysis to achieve the best possible guidelines for policy
makers. Regarding the gaps in the travel behavior change research
literature, this paper attempted to identify and suggest a
multidimensional framework in order to facilitate planning the
implemented travel behavior change interventions. A structured
mixed-method model is suggested to improve the analytic power of
the results according to the complexity of human behavior.
In order to recognize people’s attitudes towards a specific travel
mode, the Theory of Planned Behavior (TPB) was operationalized.
But in order to capture decision making processes the Transtheoretical
model of Behavior Change (TTM) was also used.
Consequently, the combination of these two theories (TTM and TPB)
has resulted in a synthesis with appropriate concepts to identify and
design an implemented travel behavior change interventions.
Abstract: The purpose of this paper is to describe the
perceptions of knowledge and information sharing by the Polish
academic community. An electronic questionnaire was used to gather
opinions of respondents. The presented results are a part of the
findings of empirical studies carried out amongst academics from
various types of universities and academia located throughout
Poland.
Abstract: This study aims to analyze ceramic employees’
occupational health and safety training expectations. To that general
objective, the study tries to examine whether occupational health and
safety training expectations of ceramic employees meaningfully
differentiate depending on demographic features and professional,
social and economic conditions. For this purpose, a questionnaire was
developed by the researcher. The research data were collected
through this questionnaire called “Questionnaire of Occupational
Health and Safety Training Expectation” (QSOHSTE). QSOHSTE
was applied to 125 ceramic employees working in Kütahya, Turkey.
Data obtained from questionnaire were analyzed via SPSS 21.
The findings, obtained from the study, revealed that employees’
agreement level to occupational health and safety training expectation
statements is generally high-level. The findings reveal that employees
expect professional interest such as increased development and
investment, preventive measures for accidents, interventions to
evaluate the working conditions, establishment of safe working
environments and sustainment of adequate equipment for
occupational health and safety training process.
Besides these findings, employees’ agreement level to
occupational health and safety training expectation statements also
varies in terms of educational level, professional seniority, income
level and perception of economic condition.
Abstract: While millings materials from old pavement surface
can be an important component of cost effective maintenance
operation, their use in maintenance projects are not uniform and well
documented. This study documents the different maintenance
practices followed by four transportation districts of New Mexico
Department of Transportation (NMDOT) in an attempt to find
whether millings are being used in maintenance projects by those
districts. Based on existing literature, a questionnaire was developed
related to six common maintenance practices. NMDOT district
personal were interviewed face to face to discuss and get answers to
that questionnaire. It revealed that NMDOT districts mainly use chip
seal and patching. Other maintenance procedures such as sand seal,
scrub seal, slurry seal, and thin overlay have limited use. Two out of
four participating districts do not have any documents on chip
sealing; rather they employ the experiences of the chip seal crew. All
districts use polymer modified high float emulsion (HFE100P) for
chip seal with an application rate ranging from 0.4 to 0.56 gallons per
square yard. Chip application rate varies from 15 to 40 lb/ square
yard. State wide, the thickness of chip seal varies from 3/8'' to 1'' and
life varies from 3 to 10 years. NMDOT districts mainly use three type
of patching: pothole, dig-out and blade patch. Pothole patches are
used for small potholes and during emergency, dig-out patches are
used for all type of potholes sometimes after pothole patching, and
blade patch is used when a significant portion of the pavement is
damaged. Pothole patches last as low as three days whereas, blade
patch lasts as long as 3 years. It was observed that all participating
districts use millings in maintenance projects.
Abstract: This experimental study evaluates the effect of using
Cognitive-Behavioral Therapy (CBT) and Multidimensional Self-
Concept Model (MSCM) in a drug prevention programme to increase
resiliency and reduce aggression among at-risk youth in Malaysia. A
number of 60 (N=60) university students who were at-risk of taking
drugs were involved in this study. Participants were identified with
self-rating scales, Adolescent Resilience Attitude Scale (ARAS) and
Aggression Questionnaire. Based on the mean score of these
instruments, the participants were divided into the treatment group,
and the control group. Data were analyzed using t-test. The finding
showed that the mean score of resiliency was increased in the
treatment group compared to the control group. It also shows that the
mean score of aggression was reduced in the treatment group
compared to the control group. Drug Prevention Programme was
found to help in enhancing resiliency and reducing aggression among
participants in the treatment group compared to the controlled group.
Implications were given regarding the preventive actions on drug
abuse among youth in Malaysia.
Abstract: China is currently the world's largest producer and distributor of electric bicycle (e-bike). The increasing number of e-bikes on the road is accompanied by rising injuries and even deaths of e-bike drivers. Therefore, there is a growing need to improve the safety structure of e-bikes. This 3D frictionless contact analysis is a preliminary, but necessary work for further structural design improvement of an e-bike. The contact analysis between e-bike and the ground was carried out as follows: firstly, the Penalty method was illustrated and derived from the simplest spring-mass system. This is one of the most common methods to satisfy the frictionless contact case; secondly, ANSYS static analysis was carried out to verify finite element (FE) models with contact pair (without friction) between e-bike and the ground; finally, ANSYS transient analysis was used to obtain the data of the penetration p(u) of e-bike with respect to the ground. Results obtained from the simulation are as estimated by comparing with that from theoretical method. In the future, protective shell will be designed following the stability criteria and added to the frame of e-bike. Simulation of side falling of the improvedsafety structure of e-bike will be confirmed with experimental data.