Abstract: Transcription factor p53 has a powerful tumor
suppressing function that is associated with many cancers. However,
p53 of the molecular weight was higher make the limitation across to
skin or cell membrane. Thymidine dinucleotide (pTT), an
oligonucleotide, can activate the p53 transcription factor. pTT is a
hydrophilic and negative charge oligonucleotide, which delivery in to
cell membrane need an appropriate carrier. The aim of this study was
to improve the bioavailability of the nucleotide fragment, thymidine
dinucleotide (pTT), using elasic liposome carriers to deliver the drug
into the skin. The study demonstrate that dioleoylphosphocholine
(DOPC) incorporated with sodium cholate at molar ratio 1:1 can
archived the particle size about 220 nm. This elastic liposome could
penetration through skin from stratum corneum to whole epidermis by
confocal laser scanning microscopy (CLSM). Moreover, we observed
the the slight increase in generation of p53 by western blot.
Abstract: This article describes Uruk, the virtual museum of
Iraq that we developed for visual exploration and retrieval of image
collections. The system largely exploits the loosely-structured
hierarchy of XML documents that provides a useful representation
method to store semi-structured or unstructured data, which does not
easily fit into existing database. The system offers users the
capability to mine and manage the XML-based image collections
through a web-based Graphical User Interface (GUI). Typically, at an
interactive session with the system, the user can browse a visual
structural summary of the XML database in order to select interesting
elements. Using this intermediate result, queries combining structure
and textual references can be composed and presented to the system.
After query evaluation, the full set of answers is presented in a visual
and structured way.
Abstract: A chord of a simple polygon P is a line segment [xy]
that intersects the boundary of P only at both endpoints x and y. A
chord of P is called an interior chord provided the interior of [xy] lies
in the interior of P. P is weakly visible from [xy] if for every point v
in P there exists a point w in [xy] such that [vw] lies in P. In this
paper star-shaped, L-convex, and convex polygons are characterized
in terms of weak visibility properties from internal chords and starshaped
subsets of P. A new Krasnoselskii-type characterization of
isothetic star-shaped polygons is also presented.
Abstract: This paper proposes a method that predicts attractive
evaluation objects. In the learning phase, the method inductively
acquires trend rules from complex sequential data. The data is
composed of two types of data. One is numerical sequential data.
Each evaluation object has respective numerical sequential data. The
other is text sequential data. Each evaluation object is described in
texts. The trend rules represent changes of numerical values related
to evaluation objects. In the prediction phase, the method applies
new text sequential data to the trend rules and evaluates which
evaluation objects are attractive. This paper verifies the effect of the
proposed method by using stock price sequences and news headline
sequences. In these sequences, each stock brand corresponds to an
evaluation object. This paper discusses validity of predicted attractive
evaluation objects, the process time of each phase, and the possibility
of application tasks.
Abstract: The purpose of this paper is to detect human in images.
This paper proposes a method for extracting human body feature descriptors consisting of projected edge component series. The feature descriptor can express appearances and shapes of human with local
and global distribution of edges. Our method evaluated with a linear SVM classifier on Daimler-Chrysler pedestrian dataset, and test with
various sub-region size. The result shows that the accuracy level of
proposed method similar to Histogram of Oriented Gradients(HOG)
feature descriptor and feature extraction process is simple and faster than existing methods.
Abstract: Vibration of thin cylindrical shells made of a
functionally gradient material composed of stainless steel and nickel
is presented. The effects of the FGM configuration are studied by
studying the frequencies of FG cylindrical shells. In this case FG
cylindrical shell has Nickel on its outer surface and stainless steel on
its inner surface. The study is carried out based on third order shear
deformation shell theory. The objective is to study the natural
frequencies, the influence of constituent volume fractions and the
effects of configurations of the constituent materials on the
frequencies. The properties are graded in the thickness direction
according to the volume fraction power-law distribution. Results are
presented on the frequency characteristics, the influence of the
constituent various volume fractions on the frequencies.
Abstract: This paper reports the three-phase (gas + liquid +
hydrate) equilibrium pressure versus temperature data for a (O3 + O2 +
CO2 + H2O) system for developing the hydrate-based technology to
preserve ozone, a chemically unstable substance, for various
industrial, medical and consumer uses. These data cover the
temperature range from 272 K to 277 K, corresponding to pressures
from 1.6 MPa to 3.1 MPa, for each of the three different (O3 +
O2)-to-CO2 or O2-to-CO2 molar ratios in the gas phase, which are
approximately 4 : 6, 5 : 5, respectively. The mole fraction of ozone in
the gas phase was ~0.03 , which are the densest ozone fraction to
artificially form O3 containing hydrate ever reported in the literature.
Based on these data, the formation of hydrate containing
high-concentration ozone, as high as 1 mass %, will be expected.
Abstract: A parallel block method based on Backward
Differentiation Formulas (BDF) is developed for the parallel solution
of stiff Ordinary Differential Equations (ODEs). Most common
methods for solving stiff systems of ODEs are based on implicit
formulae and solved using Newton iteration which requires repeated
solution of systems of linear equations with coefficient matrix, I -
hβJ . Here, J is the Jacobian matrix of the problem. In this paper,
the matrix operations is paralleled in order to reduce the cost of the
iterations. Numerical results are given to compare the speedup and
efficiency of parallel algorithm and that of sequential algorithm.
Abstract: The study of the Andaman Sea can be studied by
using the oceanic model; therefore the grid covering the study area
should be generated. This research aims to generate grid covering
the Andaman Sea, situated between longitudes 90◦E to 101◦E and
latitudes 1◦N to 18◦N. A horizontal grid is an orthogonal curvilinear
with 87 × 217 grid points. The methods used in this study are
cubic spline and bilinear interpolations. The boundary grid points
are generated by spline interpolation while the interior grid points
have to be specified by bilinear interpolation method. A vertical grid
is sigma coordinate with 15 layers of water column.
Abstract: Explosive forming is one of the unconventional
techniques in which, most commonly, the water is used as the
pressure transmission medium. One of the newest methods in
explosive forming is gas detonation forming which uses a normal
shock wave derived of gas detonation, to form sheet metals. For this
purpose a detonation is developed from the reaction of H2+O2
mixture in a long cylindrical detonation tube. The detonation wave
goes through the detonation tube and acts as a blast load on the steel
blank and forms it. Experimental results are compared with a finite
element model; and the comparison of the experimental and
numerical results obtained from strain, thickness variation and
deformed geometry is carried out. Numerical and experimental
results showed approximately 75 – 90 % similarity in formability of
desired shape. Also optimum percent of gas mixture obtained when
we mix 68% H2 with 32% O2.
Abstract: This paper presents preliminary results on modeling
and control of a quadrotor UAV. With aerodynamic concepts, a
mathematical model is firstly proposed to describe the dynamics
of the quadrotor UAV. Parameters of this model are identified by
experiments with Matlab Identify Toolbox. A group of PID controllers
are then designed based on the developed model. To verify
the developed model and controllers, simulations and experiments for
altitude control, position control and trajectory tracking are carried
out. The results show that the quadrotor UAV well follows the
referenced commands, which clearly demonstrates the effectiveness
of the proposed approach.
Abstract: With rapid technology scaling, the proportion of the
static power consumption catches up with dynamic power
consumption gradually. To decrease leakage consumption is
becoming more and more important in low-power design. This paper
presents a power-gating scheme for P-DTGAL (p-type dual
transmission gate adiabatic logic) circuits to reduce leakage power
dissipations under deep submicron process. The energy dissipations of
P-DTGAL circuits with power-gating scheme are investigated in
different processes, frequencies and active ratios. BSIM4 model is
adopted to reflect the characteristics of the leakage currents. HSPICE
simulations show that the leakage loss is greatly reduced by using the
P-DTGAL with power-gating techniques.
Abstract: Both the minimum energy consumption and
smoothness, which is quantified as a function of jerk, are generally
needed in many dynamic systems such as the automobile and the
pick-and-place robot manipulator that handles fragile equipments.
Nevertheless, many researchers come up with either solely
concerning on the minimum energy consumption or minimum jerk
trajectory. This research paper proposes a simple yet very interesting
when combining the minimum energy and jerk of indirect jerks
approaches in designing the time-dependent system yielding an
alternative optimal solution. Extremal solutions for the cost functions
of the minimum energy, the minimum jerk and combining them
together are found using the dynamic optimization methods together
with the numerical approximation. This is to allow us to simulate
and compare visually and statistically the time history of state inputs
employed by combining minimum energy and jerk designs. The
numerical solution of minimum direct jerk and energy problem are
exactly the same solution; however, the solutions from problem of
minimum energy yield the similar solution especially in term of
tendency.
Abstract: Recently the use of data mining to scientific bibliographic data bases has been implemented to analyze the pathways of the knowledge or the core scientific relevances of a laureated novel or a country. This specific case of data mining has been named citation mining, and it is the integration of citation bibliometrics and text mining. In this paper we present an improved WEB implementation of statistical physics algorithms to perform the text mining component of citation mining. In particular we use an entropic like distance between the compression of text as an indicator of the similarity between them. Finally, we have included the recently proposed index h to characterize the scientific production. We have used this web implementation to identify users, applications and impact of the Mexican scientific institutions located in the State of Morelos.
Abstract: The Kumamoto area, Kyushu, Japan has 1,041km2 in
area and about 1milion in population. This area is a greatest area in Japan which depends on groundwater for all of drinking water. Quantity of this local groundwater use is about 200MCM during the
year. It is understood that the main recharging area of groundwater exist in the rice field zone which have high infiltrate height ahead of
100mm/ day of the irrigated water located in the middle area of the Shira-River Basin. However, by decrease of the paddy-rice planting
area by urbanization and an acreage reduction policy, the groundwater income and expenditure turned worse. Then Kumamoto city and four
companies expended financial support to increase recharging water to
underground by ponded water in the field from 2004.
In this paper, the author reported the situation of recovery of groundwater by recharge and estimates the efficiency of recharge by
statistical method.
Abstract: In North America, Most power distribution systems
employ a four-wire multi-grounded neutral (MGN) design. This paper has explained the inherent characteristics of multi-grounded three-phase four-wire distribution systems under unbalanced
situations. As a result, the mechanism of voltage swell and voltage sag in MGN feeders becomes difficult to understand. The simulation
tool that has been used in this paper is MATLAB under Windows software. In this paper the equivalent model of a full-scale multigrounded
distribution system implemented by MATLAB is
introduced. The results are expected to help utility engineers to understand the impact of MGN on distribution system operations.
Abstract: The Spiral development model has been used
successfully in many commercial systems and in a good number of
defense systems. This is due to the fact that cost-effective
incremental commitment of funds, via an analogy of the spiral model
to stud poker and also can be used to develop hardware or integrate
software, hardware, and systems. To support adaptive, semantic
collaboration between domain experts and knowledge engineers, a
new knowledge engineering process, called Spiral_OWL is proposed.
This model is based on the idea of iterative refinement, annotation
and structuring of knowledge base. The Spiral_OWL model is
generated base on spiral model and knowledge engineering
methodology. A central paradigm for Spiral_OWL model is the
concentration on risk-driven determination of knowledge engineering
process. The collaboration aspect comes into play during knowledge
acquisition and knowledge validation phase. Design rationales for the
Spiral_OWL model are to be easy-to-implement, well-organized, and
iterative development cycle as an expanding spiral.
Abstract: In mobile environments, unspecified numbers of transactions
arrive in continuous streams. To prove correctness of their
concurrent execution a method of modelling an infinite number of
transactions is needed. Standard database techniques model fixed
finite schedules of transactions. Lately, techniques based on temporal
logic have been proposed as suitable for modelling infinite schedules.
The drawback of these techniques is that proving the basic
serializability correctness condition is impractical, as encoding (the
absence of) conflict cyclicity within large sets of transactions results
in prohibitively large temporal logic formulae. In this paper, we show
that, under certain common assumptions on the graph structure of
data items accessed by the transactions, conflict cyclicity need only
be checked within all possible pairs of transactions. This results in
formulae of considerably reduced size in any temporal-logic-based
approach to proving serializability, and scales to arbitrary numbers
of transactions.
Abstract: This paper describes an automatic algorithm to restore
the shape of three-dimensional (3D) left ventricle (LV) models created
from magnetic resonance imaging (MRI) data using a geometry-driven
optimization approach. Our basic premise is to restore the LV shape
such that the LV epicardial surface is smooth after the restoration. A
geometrical measure known as the Minimum Principle Curvature (κ2)
is used to assess the smoothness of the LV. This measure is used to
construct the objective function of a two-step optimization process.
The objective of the optimization is to achieve a smooth epicardial
shape by iterative in-plane translation of the MRI slices.
Quantitatively, this yields a minimum sum in terms of the magnitude
of κ
2, when κ2 is negative. A limited memory quasi-Newton algorithm,
L-BFGS-B, is used to solve the optimization problem. We tested our
algorithm on an in vitro theoretical LV model and 10 in vivo
patient-specific models which contain significant motion artifacts. The
results show that our method is able to automatically restore the shape
of LV models back to smoothness without altering the general shape of
the model. The magnitudes of in-plane translations are also consistent
with existing registration techniques and experimental findings.
Abstract: The aim of this research is to design a collaborative
framework that integrates risk analysis activities into the geospatial
database design (GDD) process. Risk analysis is rarely undertaken
iteratively as part of the present GDD methods in conformance to
requirement engineering (RE) guidelines and risk standards.
Accordingly, when risk analysis is performed during the GDD, some
foreseeable risks may be overlooked and not reach the output
specifications especially when user intentions are not systematically
collected. This may lead to ill-defined requirements and ultimately in
higher risks of geospatial data misuse. The adopted approach consists
of 1) reviewing risk analysis process within the scope of RE and
GDD, 2) analyzing the challenges of risk analysis within the context
of GDD, and 3) presenting the components of a risk-based
collaborative framework that improves the collection of the
intended/forbidden usages of the data and helps geo-IT experts to
discover implicit requirements and risks.