Abstract: This paper deals with a new way for designing
external fixators applied in traumatology and orthopaedics. These
fixators can be applied in the treatment of open and unstable
fractures or for lengthening human or animal bones etc. The new
design is based on the development of Ilizarov and other techniques
(i.e. shape and weight optimalization based on composite materials,
application of smart materials, nanotechnology, low x-ray absorption,
antibacterial protection, patient's comfort, reduction in the duration
of the surgical treatment, and cost).
Abstract: Many well-known interconnection networks, such as kary n-cubes, recursive circulant graphs, generalized recursive circulant graphs, circulant graphs and so on, are shown to belong to the family of cycle composition networks. Recently, various studies about mutually independent hamiltonian cycles, abbreviated as MIHC-s, on interconnection networks are published. In this paper, using an improved construction method, we obtain MIHC-s on cycle composition networks with a much weaker condition than the known result. In fact, we established the existence of MIHC-s in the cycle composition networks and the result is optimal in the sense that the number of MIHC-s we constructed is maximal.
Abstract: Seismic design may require non-conventional
concept, due to the fact that the stiffness and layout of the structure
have a great effect on the overall structural behaviour, on the seismic
load intensity as well as on the internal force distribution. To find an
economical and optimal structural configuration the key issue is the
optimal design of the lateral load resisting system. This paper focuses
on the optimal design of regular, concentric braced frame (CBF)
multi-storey steel building structures. The optimal configurations are
determined by a numerical method using genetic algorithm approach,
developed by the authors. Aim is to find structural configurations
with minimum structural cost. The design constraints of objective
function are assigned in accordance with Eurocode 3 and Eurocode 8
guidelines. In this paper the results are presented for various building
geometries, different seismic intensities, and levels of energy
dissipation.
Abstract: Lipases are enzymes particularly amenable for
immobilization by entrapment methods, as they can work equally
well in aqueous or non-conventional media and long-time stability of
enzyme activity and enantioselectivity is needed to elaborate more
efficient bioprocesses. The improvement of Pseudomonas
fluorescens (Amano AK) lipase characteristics was investigated by
optimizing the immobilization procedure in hybrid organic-inorganic
matrices using ionic liquids as additives. Ionic liquids containing a
more hydrophobic alkyl group in the cationic moiety are beneficial
for the activity of immobilized lipase. Silanes with alkyl- or aryl
nonhydrolizable groups used as precursors in combination with
tetramethoxysilane could generate composites with higher
enantioselectivity compared to the native enzyme in acylation
reactions of secondary alcohols. The optimal effect on both activity
and enantioselectivity was achieved for the composite made from
octyltrimethoxysilane and tetramethoxysilane at 1:1 molar ratio (60%
increase of total activity following immobilization and enantiomeric
ratio of 30). Ionic liquids also demonstrated valuable properties as
reaction media for the studied reactions, comparable with the usual
organic solvent, hexane.
Abstract: In this paper, we consider the effect of the initial
sample size on the performance of a sequential approach that used
in selecting a good enough simulated system, when the number
of alternatives is very large. We implement a sequential approach
on M=M=1 queuing system under some parameter settings, with a
different choice of the initial sample sizes to explore the impacts on
the performance of this approach. The results show that the choice
of the initial sample size does affect the performance of our selection
approach.
Abstract: Bones are dynamic and responsive organs, they
regulate their strength and mass according to the loads which they are subjected. Because, the Wnt/β-catenin pathway has profound
effects on the regulation of bone mass, we hypothesized that mechanical loading of bone cells stimulates Wnt/β-catenin signaling, which results in the generation of new bone mass.
Mechanical loading triggers the secretion of the Wnt molecule, which after binding to transmembrane proteins, causes GSK-3β (Glycogen synthase kinase 3 beta) to cease the phosphorylation of β-catenin. β-catenin accumulation in the cytoplasm, followed by its
transport into the nucleus, binding to transcription factors (TCF/LEF)
that initiate transcription of genes related to bone formation. To test this hypothesis, we used TOPGAL (Tcf Optimal Promoter
β-galactosidase) mice in an experiment in which cyclic loads were
applied to the forearm. TOPGAL mice are reporters for cells effected
by the Wnt/β-catenin signaling pathway. TOPGAL mice are genetically engineered mice in which transcriptional activation of β-
catenin, results in the production of an enzyme, β-galactosidase. The
presence of this enzyme allows us to localize transcriptional
activation of β-catenin to individual cells, thereby, allowing us to quantify the effects that mechanical loading has on the Wnt/β-catenin pathway and new bone formation. The ulnae of loaded TOPGAL
mice were excised and transverse slices along different parts of the
ulnar shaft were assayed for the presence of β-galactosidase.
Our results indicate that loading increases β-catenin transcriptional
activity in regions where this pathway is already primed (i.e. where basal activity is already higher) in a load magnitude dependent
manner. Further experiments are needed to determine the temporal and spatial activation of this signaling in relation to bone formation.
Abstract: EGOTHOR is a search engine that indexes the Web
and allows us to search the Web documents. Its hit list contains URL
and title of the hits, and also some snippet which tries to shortly
show a match. The snippet can be almost always assembled by an
algorithm that has a full knowledge of the original document (mostly
HTML page). It implies that the search engine is required to store
the full text of the documents as a part of the index.
Such a requirement leads us to pick up an appropriate compression
algorithm which would reduce the space demand. One of the solutions
could be to use common compression methods, for instance gzip or
bzip2, but it might be preferable if we develop a new method which
would take advantage of the document structure, or rather, the textual
character of the documents.
There already exist a special compression text algorithms and
methods for a compression of XML documents. The aim of this
paper is an integration of the two approaches to achieve an optimal
level of the compression ratio
Abstract: The aim of this paper is to express the input-output
matrix as a linear ordering problem which is classified as an NP-hard
problem. We then use a Tabu search algorithm to find the best
permutation among sectors in the input-output matrix that will give
an optimal solution. This optimal permutation can be useful in
designing policies and strategies for economists and government in
their goal of maximizing the gross domestic product.
Abstract: Exclusive breastfeeding is the feeding of a baby on no other milk apart from breast milk. Exclusive breastfeeding during the first 6 months of life is of fundamental importance because it supports optimal growth and development during infancy and reduces the risk of obliterating diseases and problems. Moreover, in developed countries, exclusive breastfeeding has decreased the incidence and/or severity of diarrhea, lower respiratory infection and urinary tract infection. In this paper, we study the factors that influence exclusive breastfeeding and use the Generalized Poisson regression model to analyze the practices of exclusive breastfeeding in Mauritius. We develop two sets of quasi-likelihood equations (QLE)to estimate the parameters.
Abstract: Border Gateway Protocol (BGP) is the standard routing protocol between various autonomous systems (AS) in the internet. In the event of failure, a considerable delay in the BGP convergence has been shown by empirical measurements. During the convergence time the BGP will repeatedly advertise new routes to some destination and withdraw old ones until it reach a stable state. It has been found that the KEEPALIVE message timer and the HOLD time are tow parameters affecting the convergence speed. This paper aims to find the optimum value for the KEEPALIVE timer and the HOLD time that maximally reduces the convergence time without increasing the traffic. The KEEPALIVE message timer optimal value founded by this paper is 30 second instead of 60 seconds, and the optimal value for the HOLD time is 90 seconds instead of 180 seconds.
Abstract: There are three approaches to complete Bayesian
Network (BN) model construction: total expert-centred, total datacentred,
and semi data-centred. These three approaches constitute the
basis of the empirical investigation undertaken and reported in this
paper. The objective is to determine, amongst these three
approaches, which is the optimal approach for the construction of a
BN-based model for the performance assessment of students-
laboratory work in a virtual electronic laboratory environment. BN
models were constructed using all three approaches, with respect to
the focus domain, and compared using a set of optimality criteria. In
addition, the impact of the size and source of the training, on the
performance of total data-centred and semi data-centred models was
investigated. The results of the investigation provide additional
insight for BN model constructors and contribute to literature
providing supportive evidence for the conceptual feasibility and
efficiency of structure and parameter learning from data. In addition,
the results highlight other interesting themes.
Abstract: Smart Dust particles, are small smart materials used for generating weather maps. We investigate question of the optimal number of Smart Dust particles necessary for generating precise, computationally feasible and cost effective 3–D weather maps. We also give an optimal matching algorithm for the generalized scenario, when there are N Smart Dust particles and M ground receivers.
Abstract: The Comparison analysis of the Wald-s and Bayestype sequential methods for testing hypotheses is offered. The merits of the new sequential test are: universality which consists in optimality (with given criteria) and uniformity of decision-making regions for any number of hypotheses; simplicity, convenience and uniformity of the algorithms of their realization; reliability of the obtained results and an opportunity of providing the errors probabilities of desirable values. There are given the Computation results of concrete examples which confirm the above-stated characteristics of the new method and characterize the considered methods in regard to each other.
Abstract: In this paper, we seek to determine one reasonable
local hub port and optimal routes for a containership fleet,
performing pick-ups and deliveries, between the hub and spoke ports
in a same region. The relationship between a hub port, and traffic in
feeder lines is analyzed. A new network planning method is proposed,
an integrated hub port location and route design, a capacitated vehicle
routing problem with pick-ups, deliveries and time deadlines are
formulated and solved using an improved genetic algorithm for
positioning the hub port and establishing routes for a containership
fleet. Results on the performance of the algorithm and the feasibility
of the approach show that a relatively small fleet of containerships
could provide efficient services within deadlines.
Abstract: Modeling of the dynamic behavior and motion are
renewed interest in the improved tractive performance of an
intelligent air-cushion tracked vehicle (IACTV). This paper presents
a new dynamical model for the forces on the developed small scale
intelligent air-cushion tracked vehicle moving over swamp peat. The
air cushion system partially supports the 25 % of vehicle total weight
in order to make the vehicle ground contact pressure 7 kN/m2. As the
air-cushion support system can adjust automatically on the terrain, so
the vehicle can move over the terrain without any risks. The springdamper
system is used with the vehicle body to control the aircushion
support system on any undulating terrain by making the
system sinusoidal form. Experiments have been carried out to
investigate the relationships among tractive efficiency, slippage,
traction coefficient, load distribution ratio, tractive effort, motion
resistance and power consumption in given terrain conditions.
Experiment and simulation results show that air-cushion system
improves the vehicle performance by keeping traction coefficient of
71% and tractive efficiency of 62% and the developed model can
meet the demand of transport efficiency with the optimal power
consumption.
Abstract: Selection of the best possible set of suppliers has a
significant impact on the overall profitability and success of any
business. For this reason, it is usually necessary to optimize all
business processes and to make use of cost-effective alternatives for
additional savings. This paper proposes a new efficient context-aware
supplier selection model that takes into account possible changes of
the environment while significantly reducing selection costs. The
proposed model is based on data clustering techniques while
inspiring certain principles of online algorithms for an optimally
selection of suppliers. Unlike common selection models which re-run
the selection algorithm from the scratch-line for any decision-making
sub-period on the whole environment, our model considers the
changes only and superimposes it to the previously defined best set
of suppliers to obtain a new best set of suppliers. Therefore, any recomputation
of unchanged elements of the environment is avoided
and selection costs are consequently reduced significantly. A
numerical evaluation confirms applicability of this model and proves
that it is a more optimal solution compared with common static
selection models in this field.
Abstract: An optimal power flow (OPF) based on particle swarm
optimization (PSO) was developed with more realistic generator
security constraint using the capability curve instead of only Pmin/Pmax
and Qmin/Qmax. Neural network (NN) was used in designing digital
capability curve and the security check algorithm. The algorithm is
very simple and flexible especially for representing non linear
generation operation limit near steady state stability limit and under
excitation operation area. In effort to avoid local optimal power flow
solution, the particle swarm optimization was implemented with
enough widespread initial population. The objective function used in
the optimization process is electric production cost which is
dominated by fuel cost. The proposed method was implemented at
Java Bali 500 kV power systems contain of 7 generators and 20
buses. The simulation result shows that the combination of generator
power output resulted from the proposed method was more economic
compared with the result using conventional constraint but operated
at more marginal operating point.
Abstract: The main goal of this paper is to study Statistical Process Control (SPC) with Exponentially Weighted Moving Average (EWMA) control chart when observations are serially-correlated. The characteristic of control chart is Average Run Length (ARL) which is the average number of samples taken before an action signal is given. Ideally, an acceptable ARL of in-control process should be enough large, so-called (ARL0). Otherwise it should be small when the process is out-of-control, so-called Average of Delay Time (ARL1) or a mean of true alarm. We find explicit formulas of ARL for EWMA control chart for Seasonal Autoregressive and Moving Average processes (SARMA) with Exponential white noise. The results of ARL obtained from explicit formula and Integral equation are in good agreement. In particular, this formulas for evaluating (ARL0) and (ARL1) be able to get a set of optimal parameters which depend on smoothing parameter (λ) and width of control limit (H) for designing EWMA chart with minimum of (ARL1).
Abstract: In this research paper we have presented control
architecture for robotic arm movement and trajectory planning using
Fuzzy Logic (FL) and Genetic Algorithms (GAs). This architecture is
used to compensate the uncertainties like; movement, friction and
settling time in robotic arm movement. The genetic algorithms and
fuzzy logic is used to meet the objective of optimal control
movement of robotic arm. This proposed technique represents a
general model for redundant structures and may extend to other
structures. Results show optimal angular movement of joints as result
of evolutionary process. This technique has edge over the other
techniques as minimum mathematics complexity used.