Abstract: Identification of cancer genes that might anticipate
the clinical behaviors from different types of cancer disease is
challenging due to the huge number of genes and small number of
patients samples. The new method is being proposed based on
supervised learning of classification like support vector machines
(SVMs).A new solution is described by the introduction of the
Maximized Margin (MM) in the subset criterion, which permits to
get near the least generalization error rate. In class prediction
problem, gene selection is essential to improve the accuracy and to
identify genes for cancer disease. The performance of the new
method was evaluated with real-world data experiment. It can give
the better accuracy for classification.
Abstract: A new and cost effective RP-HPLC method was
developed and validated for simultaneous analysis of non steroidal
anti inflammatory dugs Diclofenac sodium (DFS), Flurbiprofen
(FLP) and an opioid analgesic Tramadol (TMD) in advanced drug
delivery systems (Liposome and Microcapsules), marketed brands
and human plasma. Isocratic system was employed for the flow of
mobile phase consisting of 10 mM sodium dihydrogen phosphate
buffer and acetonitrile in molar ratio of 67: 33 with adjusted pH of
3.2. The stationary phase was hypersil ODS column (C18, 250×4.6
mm i.d., 5 μm) with controlled temperature of 30 C°. DFS in
liposomes, microcapsules and marketed drug products was
determined in range of 99.76-99.84%. FLP and TMD in
microcapsules and brands formulation were 99.78 - 99.94 % and
99.80 - 99.82 %, respectively. Single step liquid-liquid extraction
procedure using combination of acetonitrile and trichloroacetic acid
(TCA) as protein precipitating agent was employed. The detection
limits (at S/N ratio 3) of quality control solutions and plasma samples
were 10, 20, and 20 ng/ml for DFS, FLP and TMD, respectively.
The Assay was acceptable in linear dynamic range. All other
validation parameters were found in limits of FDA and ICH method
validation guidelines. The proposed method is sensitive, accurate and
precise and could be applicable for routine analysis in
pharmaceutical industry as well as in human plasma samples for
bioequivalence and pharmacokinetics studies.
Abstract: We present a preliminary x-ray study on human-hair
microstructures for a health-state indicator, in particular a cancer
case. As an uncomplicated and low-cost method of x-ray technique,
the human-hair microstructure was analyzed by wide-angle x-ray
diffractions (XRD) and small-angle x-ray scattering (SAXS). The
XRD measurements exhibited the simply reflections at the d-spacing
of 28 Å, 9.4 Å and 4.4 Å representing to the periodic distance of the
protein matrix of the human-hair macrofibrous and the diameter and
the repeated spacing of the polypeptide alpha helixes of the
photofibrils of the human-hair microfibrous, respectively. When
compared to the normal cases, the unhealthy cases including to the
breast- and ovarian-cancer cases obtained higher normalized ratios of
the x-ray diffracting peaks of 9.4 Å and 4.4 Å. This likely resulted
from the varied distributions of microstructures by a molecular
alteration. As an elemental analysis by x-ray fluorescence (XRF), the
normalized quantitative ratios of zinc(Zn)/calcium(Ca) and
iron(Fe)/calcium(Ca) were determined. Analogously, both Zn/Ca and
Fe/Ca ratios of the unhealthy cases were obtained higher than both of
the normal cases were. Combining the structural analysis by XRD
measurements and the elemental analysis by XRF measurements
exhibited that the modified fibrous microstructures of hair samples
were in relation to their altered elemental compositions. Therefore,
these microstructural and elemental analyses of hair samples will be
benefit to associate with a diagnosis of cancer and genetic diseases.
This functional method would lower a risk of such diseases by the
early diagnosis. However, the high-intensity x-ray source, the highresolution
x-ray detector, and more hair samples are necessarily
desired to develop this x-ray technique and the efficiency would be
enhanced by including the skin and fingernail samples with the
human-hair analysis.
Abstract: Objective of this study was to study and compare the effectiveness of inspectors who had different workloads for feed forward and feedback training. The visual search task was simulated to search for specified alphabets called defects. These defects were included of four alphabets in Thai and English such as s ภ, ถ, X, and V with different background. These defects were combined in the specified alphabets and were given the different three backgrounds i.e., Thai, English, and mixed English and Thai alphabets. Sixty students were chosen as a sample in this study and test for final selection subject. Finally, five subjects were taken into testing process. They were asked to search for defects after they were provided basic information. Experiment design was used factorial design and subjects were trained for feed forward and the feedback training. The results show that both trainings were affected on mean search time. It was also found that the feedback training can increase the effectiveness of visual inspectors rather than the feed forward training significantly different at the level of .05
Abstract: Descriptive statistics was performed with the aim to achieve research objective of to investigate lecturers- usage of the mobile technology for teaching. A representative sample of 20 lecturers from the Faculty of Industrial Art & Design Technology of Universiti Industri Selangor (UNISEL), Malaysia was selected as the respondents. The result attested that lecturers fully accept the concept of mobility in learning and game play is appealing concept to support classroom learning. Subsequently, analogous experience on small size of keypad, screen resolution, and navigation could be the major problematic factors to students and affect their mobile learning process. Recommendation for future research is also presented.
Abstract: Paleoclimate was reconstructed by the clay mineral
assemblages of shale units of Pabdeh (Paleocene- Oligocene), Gurpi
(Upper Cretaceous), Kazhdumi (Albian-Cenomanian) and Gadvan
(Aptian-Neocomian) formations in the Bangestan anticline. To
compare with clay minerals assemblages in these formations,
selected samples also taken from available formations in drilled wells
in Ahvaz, Marun, Karanj, and Parsi oil fields. Collected samples
prepared using standard clay mineral methodology. They were
treated as normal, glycolated and heated oriented glass slides. Their
identification was made on X-Ray diffractographs. Illite % varies
from 8 to 36. Illite quantity increased from Pabdeh to Gurpi
Formation. This may be due to dominant dry climate. Kaolinite is in
range of 12-49%. Its variation style in different formations could be a
marker of climate changes from wet to dry which is supported by the
lithological changes. Chlorite (4-28%) can also be detected in those
samples without any kaolinite. Mixed layer minerals as the mixture
of illite-chlorite and illite-vermiculite-montmorillonite are varied
from 6 to 36%, decreased during Kazhdumi deposition from the base
to the top. This result may be according to decreasing of illite
leaching process. Vermiculite was also determined in very less
quantity and found in those units without kaolinite. Montmorillonite
varies from 8 to 43%, and its presence is due to terrestrial
depositional condition. Stratigraphical documents is also supported
this idea that clay mineral distribution is a function of the climate
changes. It seems, thus, the present results can be indicated a possible
procedure for ancient climate changes evaluation.
Abstract: Studies were carried out on the comparative study of the production of Avicelase enzyme using sugarcane bagasse-SCB in two different statuses (i.e. treated and untreated SCB) by thermophilic Geobacillus stearothermophilus at 50ºC. Only four thermophilic bacterial isolates were isolated and assayed for Avicelase production using UntSCB and TSCB. Only one isolate selected as most potent and identified as G. stearothermophilus used in this study. A specific endo-β-1,4-D-glucanase (Avicelase EC 3.2.1.91) was partially purified from a thermophilic bacterial strain was isolated from different soil samples when grown on cellulose enrichment SCB substrate as the sole carbon source. Results shown that G. stearothermophilus was the better Avicelase producer strain. Avicelase had an optimum pH and temperature 7.0 and 50ºC for both UntSCB and TSCB and exhibited good pH stability between "5-8" and "4-9", however, good temperature stability between (30-80ºC) for UntSCB and TSCB, respectively. Other factors affecting the production of Avicelase were compared (i.e. SCB concentration, inoculum size and different incubation periods), all results observed and obtained were revealed that the TSCB was exhibited maximal enzyme activity in comparison with the results obtained from UntSCB, so, the TSCB was enhancing the Avicelase production.
Abstract: Current advancements in nanotechnology are dependent
on the capabilities that can enable nano-scientists to extend their eyes
and hands into the nano-world. For this purpose, a haptics (devices
capable of recreating tactile or force sensations) based system for
AFM (Atomic Force Microscope) is proposed. The system enables
the nano-scientists to touch and feel the sample surfaces, viewed
through AFM, in order to provide them with better understanding of
the physical properties of the surface, such as roughness, stiffness and
shape of molecular architecture. At this stage, the proposed work uses
of ine images produced using AFM and perform image analysis to
create virtual surfaces suitable for haptics force analysis. The research
work is in the process of extension from of ine to online process
where interaction will be done directly on the material surface for
realistic analysis.
Abstract: The purpose of this article is to propose a model designed to achieve Total Knowledge Transfer in the public health sector. The Total Knowledge Transfer Model integrated four essential organizational factors which have been under examined in totality in the literature. The research design was inductive in nature and used a case study for accomplishing the research objectives. The researcher investigated the factors that created a base to design a framework for total knowledge transfer in the public health sector. The results of this study are drawn from a fairly large sample in only two hospitals. A further research can be conducted to cover more responses from a wider health sector. The Total Knowledge Transfer Model is essential to improve the transfer and application of total common health knowledge.
Abstract: Slag sample from copper smelting operation in a
water jacket furnace from DRC plant was used. The study intends to
determine the effect of cooling in the extraction of base metals. The
cooling methods investigated were water quenching, air cooling and
furnace cooling. The latter cooling ways were compared to the
original as received slag. It was observed that, the cooling rate of the
slag affected the leaching of base metals as it changed the phase
distribution in the slag and the base metals distribution within the
phases. It was also found that fast cooling of slag prevented
crystallization and produced an amorphous phase that encloses the
base metals. The amorphous slags from the slag dumps were more
leachable in acidic medium (HNO3) which leached 46%Cu, 95% Co,
85% Zn, 92% Pb and 79% Fe with no selectivity at pH0, than in
basic medium (NH4OH). The leachability was vice versa for the
modified slags by quenching in water which leached 89%Cu with a
high selectivity as metal extractions are less than 1% for Co, Zn, Pb
and Fe at ambient temperature and pH12. For the crystallized slags,
leaching of base metals increased with the increase of temperature
from ambient temperature to 60°C and decreased at the higher
temperature of 80°C due to the evaporation of the ammonia solution
used for basic leaching, the total amounts of base metals that were
leached in slow cooled slags were very low compared to the
quenched slag samples.
Abstract: Job stress is one of the most important concepts for
the today-s corporate as well as institutional world. The current study
is conducted to identify the causes of faculty stress at Higher
Education in Pakistan. For the purpose, Public & Private Business
Schools of Punjab is selected as representative of Pakistan. A sample
of 300 faculty members (214 males, 86 females) responded to the
survey. Regression analysis shows that the Workload, Student
Related issues and Role Conflicts are the major sources contributing
significantly towards producing stress. The study also revealed that
Private sector faculty members experienced more stress as compared
to faculty in Public sector Business Schools. Moreover, females,
younger ages, lower designation & low qualification faculty
members experience more stress as compared to males, older ages,
higher designation and high qualification. The study yield many
significant results for the policy makers of Business Institutions.
Abstract: Heavy metal transfer in soil profiles is a major
environmental concern because even slow transport through the soil
may eventually lead to deterioration of groundwater quality. The use
of sewage sludge and effluents from wastewater treatment plants for
irrigation of agricultural lands is on the rise particularly in peri-urban
area of developing countries. In this study soil samples under sludge
application and wastewater irrigation were studied and soil samples
were collected in the soil profiles from the surface to 100 cm in
depth. For this purpose, three plots were made in a treatment plant in
south of Tehran-Iran. First plot was irrigated just with effluent from
wastewater treatment plant, second plot with simulated heavy metals
concentration equal 50 years irrigation and in third plot sewage
sludge and effluent was used. Trace metals concentration (Cd, Cu)
were determined for soil samples. The results indicate movement of
metals was observed, but the most concentration of metals was found
in topsoil samples. The most of Cadmium concentration was
measured in the topsoil of plot 3, 4.5mg/kg and Maximum cadmium
movement was observed in 0-20 cm. The most concentration of
copper was 27.76mg/kg, and maximum percolation in 0-20 cm.
Metals (Cd, Cu) were measured in leached water. Preferential flow
and metal complexation with soluble organic apparently allow
leaching of heavy metals.
Abstract: Polypropylene blended with natural oil and pigment additives has been studied. Different formulations for each compound were made into polybag used for cultivation of oil palm seedlings for strength and mechanical properties studies. One group of sample was exposed under normal sunlight to initiate degradation and another group of sample was placed under shaded area for five months. All samples were tested for tensile strength to determine the degradation effects. The tensile strength of directly exposed sunlight samples and shaded area showed up to 50% and 25% degradation respectively. However, similar reduction of Young’s modulus for all samples was found for both exposures. Structural investigations were done using FTIR to detect deformation. The natural additives that were used in the studies were all natural and environmental friendly
Abstract: Although the Vietnamese catfish farming has grown
at very high rates in recent years, the industry has also faced many
problems affecting its sustainability. This paper studies the
perceptions of catfish farmers regarding risk and risk management
strategies in their production activities. Specifically, the study aims
to measure the consequences, likelihoods, and levels of risks as well
as the efficacy of risk management in Vietnamese catfish farming.
Data for the study were collected through a sample of 261 catfish
farmers in the Mekong Delta, Vietnam using a questionnaire survey
in 2008. Results show that, in general, price and production risks
were perceived as the most important risks. Farm management and
technical measures were perceived more effective than other kinds of
risk management strategies in risk reduction. Although price risks
were rated as important risks, price risk management strategies were
not perceived as important measures for risk mitigation. The results
of the study are discussed to provide implications for various
industry stakeholders, including policy makers, processors, advisors,
and developers of new risk management strategies.
Abstract: The present paper is a case study about exploitation of
Kheir Abad river (Khoozestan, Iran) water resources and the
problems caused by river sediments around the pumping stations.
The weak points and strong points of Boneh Basht pumping station
have been studied by experienced experts, work teams, and
consulting engineers and technical and executive solutions have been
suggested. Therefore, the suggestions of this article are based on the
performed studies and are proposed in order to evaluate the logical
solutions.
Rather complicated processes resulting from the interaction of
water flows and sediments observed at Boneh Basht pumping station
occur at other pumping stations in almost the same way. Therefore,
Boneh Basht pumping station can be selected as a sample (pilot) and
up-to-date theories and experiences can be applied to this station and
the results can be offered to other stations.
Abstract: Learning using labeled and unlabelled data has
received considerable amount of attention in the machine learning
community due its potential in reducing the need for expensive
labeled data. In this work we present a new method for combining
labeled and unlabeled data based on classifier ensembles. The model
we propose assumes each classifier in the ensemble observes the
input using different set of features. Classifiers are initially trained
using some labeled samples. The trained classifiers learn further
through labeling the unknown patterns using a teaching signals that is
generated using the decision of the classifier ensemble, i.e. the
classifiers self-supervise each other. Experiments on a set of object
images are presented. Our experiments investigate different classifier
models, different fusing techniques, different training sizes and
different input features. Experimental results reveal that the proposed
self-supervised ensemble learning approach reduces classification
error over the single classifier and the traditional ensemble classifier
approachs.
Abstract: A high-linearity and high-speed current-mode sampleand-
hold circuit is designed and simulated using a 0.25μm CMOS
technology. This circuit design is based on low voltage and it utilizes
a fully differential circuit. Due to the use of only two switches the
switch related noise has been reduced. Signal - dependent -error is
completely eliminated by a new zero voltage switching technique.
The circuit has a linearity error equal to ±0.05μa, i.e. 12-bit
accuracy with a ±160 μa differential output - input signal frequency
of 5MHZ, and sampling frequency of 100 MHZ. Third
harmonic is equal to –78dB.
Abstract: The main objectives of this study were to identify
attributes that influence customer satisfaction and determine their
relationships with customer satisfaction. The variables included in
this research are place/ambience, food quality and service quality as
independent variables and customer satisfaction as the dependent
variable. A survey questionnaire which consisted of three parts to
measure demographic factors, independent variables, and dependent
variables was constructed based on items determined by past
research. 149 respondents from one of the well known hotel in Kuala
Lumpur, MALAYSIA were selected as a sample. Psychometric
testing was conducted to determine the reliability and validity of the
questionnaire. From the findings, there were positive significant
relationship between place/ambience (r=0.563**, p=0.000) and
service quality (r=0.544**, p=0.000) with customer satisfaction.
However, although relationship between food quality and customer
satisfaction was significant, it was in the negative direction (r=-
0.268**, p=0.001). New findings were discovered after conducting
this research and previous research findings were strengthened by the
results of this research. Future researchers could concentrate on
determining attributes that influence customer satisfaction when
cost/price is not a factor and reasons for place/ambience is currently
becoming the leading factor in determining customer satisfaction.
Abstract: ZnO nanostructure were synthesized via microwave
method using zinc acetate as starting material, guanidinium as
structure directing agents, and water as solvent.. This work
investigates the photodegradation of azo dyes using the ZnO Flowerlike
in aqueous solutions. As synthesized ZnO samples were
characterized using X-Ray powder diffraction (XRD), scanning
electron microscopy (SEM), and FTIR spectroscopy.In this work
photodecolorization of congored azo dye under UV irradiation by
nano ZnO was studied.
Abstract: Language Reforms and potential use of ICTs has been a focal area of Higher Education Commission of Pakistan. Efforts are being accelerated to incorporate fast expanding ICTs to bring qualitative improvement in language instruction in higher education. This paper explores how university teachers are benefitting from ICTs to make their English class effective and what type of problems they face in practicing ICTs during their lectures. An in-depth qualitative study was employed to understand why language teachers tend to use ICTs in their instruction and how they are practicing it. A sample of twenty teachers from five universities located in Islamabad, three from public sector and two from private sector, was selected on non-random (Snowball) sampling basis. An interview with 15 semi-structured items was used as research instruments to collect data. The findings reveal that business English teaching is facilitated and improved through the use of ICTs. The language teachers need special training regarding the practices and implementation of ICTs. It is recommended that initiatives might be taken to equip university language teachers with modern methodology incorporating ICTs as focal area and efforts might be made to remove barriers regarding the training of language teachers and proper usage of ICTs.