Abstract: Radiolabeled cyclic RGD peptides targeting integrin αvβ3 are reported as promising agents for the early diagnosis of metastatic tumors. With an aim to improve tumor uptake and retention of the peptide, cyclic RGD peptide dimer E[c (RGDfK)] 2 (E = Glutamic acid, f = phenyl alanine, K = lysine) coupled to the bifunctional chelator DOTA was custom synthesized and radiolabelled with 68Ga. Radiolabelling of cyclic RGD peptide dimer with 68Ga was carried out using HEPES buffer and biological evaluation of the complex was done in nude mice bearing HT29 tumors.
Abstract: In this paper, a framework is presented trying to make
the most secure web system out of the available generic and web
security technology which can be used as a guideline for
organizations building their web sites. The framework is designed to
provide necessary security services, to address the known security
threats, and to provide some cover to other security problems
especially unknown threats. The requirements for the design are
discussed which guided us to the design of secure web system. The
designed security framework is then simulated and various quality of
service (QoS) metrics are calculated to measure the performance of
this system.
Abstract: In this paper, a novel method for a biometric system based on the ECG signal is proposed, using spectral coefficients computed through linear predictive coding (LPC). ECG biometric systems have traditionally incorporated characteristics of fiducial points of the ECG signal as the feature set. These systems have been shown to contain loopholes and thus a non-fiducial system allows for tighter security. In the proposed system, incorporating non-fiducial features from the LPC spectrum produced a segment and subject recognition rate of 99.52% and 100% respectively. The recognition rates outperformed the biometric system that is based on the wavelet packet decomposition (WPD) algorithm in terms of recognition rates and computation time. This allows for LPC to be used in a practical ECG biometric system that requires fast, stringent and accurate recognition.
Abstract: Turbulent heat transfer to fluid flow through channel with triangular ribs of different angles are presented in this paper. Ansys 14 ICEM and Ansys 14 Fluent are used for meshing process and solving Navier stokes equations respectively. In this investigation three angles of triangular ribs with the range of Reynolds number varied from 20000 to 60000 at constant surface temperature are considered. The results show that the Nusselt number increases with the increase of Reynolds number for all cases at constant surface temperature. According to the profile of local Nusselt number on ribs walled of channel, the peak is at the midpoint between the two ribs. The maximum value of average Nusselt number is obtained for triangular ribs of angel 60°and at Reynolds number of 60000 compared to the Nusselt number for the ribs of angel 90° and 45° and at same Reynolds number. The recirculation regions generated by the ribs corresponding to the velocity streamline show the largest recirculation region at triangular ribs of angle 60° which also provides the highest enhancement of heat transfer.
Abstract: Seasonal variability of nutrients concentration in the Baltic Sea using the 3D ecosystem numerical model 3D-CEMBS has been investigated. Additionally this study shows horizontal and vertical distribution of nutrients in the Baltic Sea. Model domain is an extended Baltic Sea area divided into 600x640 horizontal grid cells. Aside from standard hydrodynamic parameters 3D-CEMBS produces modeled ecological variables such as: three types of phytoplankton, two detrital classes, dissolved oxygen and the nutrients (nitrate, ammonium, phosphate and silicate). The presented model allows prediction of parameters that describe distribution of nutrients concentration and phytoplankton biomass. 3D-CEMBS can be used to study the effect of different hydrodynamic and biogeochemical processes on distributions of these variables in a larger scale.
Abstract: In this paper, a two-dimensional mathematical model is developed for estimating the extent of inland inundation due to Indonesian tsunami of 2004 along the coastal belts of Peninsular Malaysia and Thailand. The model consists of the shallow water equations together with open and coastal boundary conditions. In order to route the water wave towards the land, the coastal boundary is treated as a time dependent moving boundary. For computation of tsunami inundation, the initial tsunami wave is generated in the deep ocean with the strength of the Indonesian tsunami of 2004. Several numerical experiments are carried out by changing the slope of the beach to examine the extent of inundation with slope. The simulated inundation is found to decrease with the increase of the slope of the orography. Correlation between inundation / recession and run-up are found to be directly proportional to each other.
Abstract: This study uses natural water and the surface properties of powdered activated carbon to acclimatize organics, forming biofilms on the surface of powdered activated carbon. To investigate the influence of different hydraulic retention times on the removal efficacy of trace organics in raw water, and to determine the optimal hydraulic retention time of a biological powdered activated carbon system, this study selects ozone-treated water processed by Feng-shan Advanced Water Purification Plant in southern Taiwan for the experiment. The evaluation indicators include assimilable organic carbon, dissolved organic carbon, and total organic carbon. The results of this study can improve the quality of drinking water treated using advanced water purification procedures.
Abstract: A code has been developed in Mathematica using
Direct Simulation Monte Carlo (DSMC) technique. The code was
tested for 2-D air flow around a circular cylinder. Same geometry
and flow properties were used in FLUENT 6.2 for comparison. The
results obtained from Mathematica simulation indicated significant
agreement with FLUENT calculations, hence providing insight into
particle nature of fluid flows.
Abstract: Some theoretical and experimental aspects related to
the conceptual analyses concerning the direct correspondence
identification between the shape, area and orientation of plantar
pressure and obtaining adequate corrective insoles by rapid
prototyping are presented in this paper. In the first part of the paper
there is the theoretical-correlative concept, which is the fundament of
correspondence deduction between plantar surface characteristics and
respectively corrective insoles. In the second part of the paper the
experimental equipment used to analyze and perform the
correspondence stages and then the integral ones between the
analyzed foot shapes and the ones with corrective insoles is
presented. In the final parte the results used to adapt the insoles
obtained by rapid prototyping but also some specific aspects and
conclusions of the conceptual analysis of direct and rapid
correspondence are shown.
Abstract: The main purpose of the research is to address the role of psychological harassment behaviors (mobbing) to which employees are exposed and personality characteristics over work alienation. Research population was composed of the employees of Provincial Special Administration. A survey with four sections was created to measure variables and reach out the basic goals of the research. Correlation and step-wise regression analyses were performed to investigate the separate and overall effects of sub-dimensions of psychological harassment behaviors and personality characteristic on work alienation of employees. Correlation analysis revealed significant but weak relationships between work alienation and psychological harassment and personality characteristics. Step-wise regression analysis revealed also significant relationships between work alienation variable and assault to personality, direct negative behaviors (sub dimensions of mobbing) and openness (sub-dimension of personality characteristics). Each variable was introduced into the model step by step to investigate the effects of significant variables in explaining the variations in work alienation. While the explanation ratio of the first model was 13%, the last model including three variables had an explanation ratio of 24%.
Abstract: Let T and S be a subspace of Cn and Cm, respectively.
Then for A ∈ Cm×n satisfied AT ⊕ S = Cm, the generalized
inverse A(2)
T,S is given by A(2)
T,S = (PS⊥APT )†. In this paper, a
finite formulae is presented to compute generalized inverse A(2)
T,S
under the concept of restricted inner product, which defined as <
A,B >T,S=< PS⊥APT,B > for the A,B ∈ Cm×n. By this
iterative method, when taken the initial matrix X0 = PTA∗PS⊥, the
generalized inverse A(2)
T,S can be obtained within at most mn iteration
steps in absence of roundoff errors. Finally given numerical example
is shown that the iterative formulae is quite efficient.
Abstract: Membrane distillation (MD) is a rising technology for
seawater or brine desalination process. In this work, an air gap
membrane distillation (AGMD) performance was investigated for
aqueous NaCl solution along with natural ground water and seawater.
In order to enhance the performance of the AGMD process in
desalination, that is, to get more flux, it is necessary to study the
effect of operating parameters on the yield of distillate water. The
influence of operational parameters such as feed flow rate, feed
temperature, feed salt concentration, coolant temperature and air gap
thickness on the membrane distillation (MD) permeation flux have
been investigated for low and high salt solution. the natural
application of ground water and seawater over 90 h continuous
operation, scale deposits observed on the membrane surface and
reduction in flux represents 23% for ground water and 60% for
seawater, in 90 h. This reduction was eliminated (less than 14 %) by
acidification of feed water. Hence, promote the research attention in
apply of AGMD for the ground water as well as seawater
desalination over today-s conventional RO operation.
Abstract: The small interfering RNA (siRNA) alters the
regulatory role of mRNA during gene expression by translational
inhibition. Recent studies show that upregulation of mRNA because
serious diseases like cancer. So designing effective siRNA with good
knockdown effects plays an important role in gene silencing. Various
siRNA design tools had been developed earlier. In this work, we are
trying to analyze the existing good scoring second generation siRNA
predicting tools and to optimize the efficiency of siRNA prediction
by designing a computational model using Artificial Neural Network
and whole stacking energy (%G), which may help in gene silencing
and drug design in cancer therapy. Our model is trained and tested
against a large data set of siRNA sequences. Validation of our results
is done by finding correlation coefficient of experimental versus
observed inhibition efficacy of siRNA. We achieved a correlation
coefficient of 0.727 in our previous computational model and we
could improve the correlation coefficient up to 0.753 when the
threshold of whole tacking energy is greater than or equal to -32.5
kcal/mol.
Abstract: Unsteady natural convection and heat transfer in a square cavity partially filled with porous media using a thermal
non-equilibrium model is studied in this paper. The left vertical wall is
maintained at a constant hot temperature Th and the right vertical wall
is maintained at a constant cold temperature Tc, while the horizontal
walls are adiabatic. The governing equations are obtained by applying
the Darcy model and Boussinesq approximation. COMSOL’s finite
element method is used to solve the non-dimensional governing
equations together with specified boundary conditions. The governing
parameters of this study are the Rayleigh number (Ra = 10^5, and Ra = 10^6 ), Darcy namber (Da = 10^−2, and Da = 10^−3),
the modified thermal conductivity ratio (10^−1 ≤ γ ≤ 10^4), the inter-phase heat transfer coefficien (10^−1 ≤ H ≤ 10^3) and the
time dependent (0.001 ≤ τ ≤ 0.2). The results presented for
values of the governing parameters in terms of streamlines in both
fluid/porous-layer, isotherms of fluid in fluid/porous-layer, isotherms
of solid in porous layer, and average Nusselt number.
Abstract: Environmental investments, including ecological
projects, relating to the protection of atmosphere are today a need.
However, investing in the environment should be based on rational
management rules. This comes across a problem of selecting a
method to assess substances reduced during projects. Therefore, a
method allowing for the assessment of decision rationality has to be
found.
The purpose of this article is to present and systematise pollution
reduction assessment methods and illustrate theoretical analyses with
empirical data.
Empirical results confirm theoretical considerations, which proved
that the only method for judging pollution reduction, free of apparent
disadvantages, is the Eco 99-ratio method. To make decisions on
environmental projects, financing institutions should take into
account a rationality rule. Therefore the Eco 99-ratio method could
be applied to make decisions relating to environmental investments in
the area of air protection.
Abstract: The aim of this research is to develop the
understanding of corporate social responsibility (CSR) from
consumers- perspective toward Thai mobile service providers.
Based on the survey from 400 mobile customers, the result
shows that four dimensions of CSR of Thai mobile service
providers consist of economic, legal, ethical and philanthropic
responsibility. These four CSR factors have positive impacts
on enhancing customer satisfaction except one item of
economic responsibility - profitability to shareholders. Ethical
dimension has the strongest impact on customer satisfaction.
Economic, legal, ethical, philanthropic responsibility and
customer satisfaction have major impact on loyalty, whilst
philanthropic component mostly affects loyalty.
Abstract: The aim of this study was to develop a storm water quality improvement strategy plan (WQISP) which assists managers and decision makers of local city councils in enhancing their activities to improve regional water quality. City of Gosnells in Western Australia has been considered as a case study. The procedure on developing the WQISP consists of reviewing existing water quality data, identifying water quality issues in the study areas and developing a decision making tool for the officers, managers and decision makers. It was found that land use type is the main factor affecting the water quality. Therefore, activities, sources and pollutants related to different land use types including residential, industrial, agricultural and commercial are given high importance during the study. Semi-structured interviews were carried out with coordinators of different management sections of the regional councils in order to understand the associated management framework and issues. The issues identified from these interviews were used in preparing the decision making tool. Variables associated with the defined “value versus threat" decision making tool are obtained from the intensive literature review. The main recommendations provided for improvement of water quality in local city councils, include non-structural, structural and management controls and potential impacts of climate change.
Abstract: Location-aware computing is a type of pervasive
computing that utilizes user-s location as a dominant factor for
providing urban services and application-related usages. One of the
important urban services is navigation instruction for wayfinders in a
city especially when the user is a tourist. The services which are
presented to the tourists should provide adapted location aware
instructions. In order to achieve this goal, the main challenge is to
find spatial relevant objects and location-dependent information. The
aim of this paper is the development of a reusable location-aware
model to handle spatial relevancy parameters in urban location-aware
systems. In this way we utilized ontology as an approach which could
manage spatial relevancy by defining a generic model. Our
contribution is the introduction of an ontological model based on the
directed interval algebra principles. Indeed, it is assumed that the
basic elements of our ontology are the spatial intervals for the user
and his/her related contexts. The relationships between them would
model the spatial relevancy parameters. The implementation language
for the model is OWLs, a web ontology language. The achieved
results show that our proposed location-aware model and the
application adaptation strategies provide appropriate services for the
user.
Abstract: A new and cost effective robotic device was designed
for remote tele surgery using dual tone multi frequency technology
(DTMF). Tele system with Dual Tone Multiple Frequency has a large
capability in sending and receiving of data in hardware and software.
The robot consists of DC motors for arm movements and it is
controlled manually through a mobile phone through DTMF
Technology. The system enables the surgeon from base station to
send commands through mobile phone to the patient’s robotic system
which includes two robotic arms that translate the input into actual
instrument manipulation. A mobile phone attached to the
microcontroller 8051 which can activate robot through relays. The
Remote robot-assisted tele surgery eliminates geographic constraints
for getting surgical expertise where it is needed and allows an expert
surgeon to teach or proctor the performance of surgical technique by
real-time intervention.
Abstract: In order to accelerate the similarity search in highdimensional database, we propose a new hierarchical indexing method. It is composed of offline and online phases. Our contribution concerns both phases. In the offline phase, after gathering the whole of the data in clusters and constructing a hierarchical index, the main originality of our contribution consists to develop a method to construct bounding forms of clusters to avoid overlapping. For the online phase, our idea improves considerably performances of similarity search. However, for this second phase, we have also developed an adapted search algorithm. Our method baptized NOHIS (Non-Overlapping Hierarchical Index Structure) use the Principal Direction Divisive Partitioning (PDDP) as algorithm of clustering. The principle of the PDDP is to divide data recursively into two sub-clusters; division is done by using the hyper-plane orthogonal to the principal direction derived from the covariance matrix and passing through the centroid of the cluster to divide. Data of each two sub-clusters obtained are including by a minimum bounding rectangle (MBR). The two MBRs are directed according to the principal direction. Consequently, the nonoverlapping between the two forms is assured. Experiments use databases containing image descriptors. Results show that the proposed method outperforms sequential scan and SRtree in processing k-nearest neighbors.