Abstract: The mechanisms underlying the association between
obesity and asthma may be related to a decreased immunological
tolerance induced by a defective function of regulatory T cells
(Tregs). The aim of this study is to establish the potential link
between these diseases and CD4+, CD25+ FoxP3+ Tregs as well as T
helper cells (Ths) in children. This is a prospective case control
study. Obese (n:40), asthmatic (n:40), asthmatic obese (n:40) and
healthy children (n:40), who don't have any acute or chronic diseases,
were included in this study. Obese children were evaluated according
to WHO criteria. Asthmatic patients were chosen based on GINA
criteria. Parents were asked to fill up the questionnaire. Informed
consent forms were taken. Blood samples were marked with CD4+,
CD25+ and FoxP3+ in order to determine Tregs and Ths by flow
cytometric method. Statistical analyses were performed. p≤0.05 was
chosen as meaningful threshold. Tregs exhibiting anti-inflammatory
nature were significantly lower in obese (0,16%; p≤0,001), asthmatic
(0,25%; p≤0,01) and asthmatic obese (0,29%; p≤0,05) groups than
the control group (0,38%). Ths were counted higher in asthma group
than the control (p≤0,01) and obese (p≤0,001) groups. T cell
immunity plays important roles in obesity and asthma pathogeneses.
Decreased numbers of Tregs found in obese, asthmatic and asthmatic
obese children may help to elucidate some questions in
pathophysiology of these diseases. For HOMA-IR levels, any
significant difference was not noted between control and obese
groups, but statistically higher values were found for obese
asthmatics. The values obtained in all groups were found to be below
the critical cut off points. This finding has made the statistically
significant difference observed between Tregs of obese, asthmatic,
obese asthmatic and control groups much more valuable. These
findings will be useful in diagnosis and treatment of these disorders
and future studies are needed. The production and propagation of
Tregs may be promising in alternative asthma and obesity treatments.
Abstract: Employer branding is considered as a useful tool for
addressing the global-local problem facing complex organisations
that have operations scattered across the globe and face challenges of
dealing with the local environment alongside. Despite being an
established field of study within the Western developed world, there
is little empirical evidence concerning the relevance of employer
branding to global companies that operate in the under-developed
economies. This paper fills this gap by gaining rich insight into the
implementation of employer branding programs in a foreign
multinational operating in Pakistan dealing with the global-local
problem. The study is qualitative in nature and employs semistructured
and focus group interviews with senior/middle managers
and local frontline employees to deeply examine the phenomenon in
case organisation. Findings suggest that authenticity is required in
employer brands to enable them to respond to the local needs thereby
leading to the resolution of the global-local problem. However, the
role of signaling theory is key to the development of authentic
employer brands as it stresses on the need to establish an efficient and
effective signaling environment where in signals travel in both
directions (from signal designers to receivers and backwards) and
facilitate firms with the global-local problem. The paper also
identifies future avenues of research for the employer branding field.
Abstract: Predicting the collapse potential of a structure during
earthquakes is an important issue in earthquake engineering. Many
researchers proposed different methods to assess the collapse
potential of structures under the effect of strong ground motions.
However most of them did not consider degradation and softening
effect in hysteretic behavior. In this study, collapse potential of
SDOF systems caused by dynamic instability with stiffness and
strength degradation has been investigated. An equation was
proposed for the estimation of collapse period of SDOF system which
is a limit value of period for dynamic instability. If period of the
considered SDOF system is shorter than the collapse period then the
relevant system exhibits dynamic instability and collapse occurs.
Abstract: High performance turf reinforcement mat (HPTRM) is
one of the most advanced flexible armoring technologies for severe
erosion challenges. The effect of turbulence on the slope stability of
an earthen levee strengthened by high performance turf reinforcement
mat (HPTRM) is investigated in this study for combined storm surge
and wave overtopping conditions. The results show that turbulence
has strong influence on the slope stability during the combined storm
surge and wave overtopping conditions. Among the surge height,
peak wave force and turbulent force. The turbulent force has the
ability to stabilize the earthen levee at the large wave force the
turbulent force has strongest effect on the FS. The surge storm acts as
an independent force on the slope stability of the earthen levee. It just
adds to the effects of the turbulent force and wave force on the slope
stability of HPTRM strengthened levee.
Abstract: The paper discusses mineral water consumer market
and development policy in Georgia, the tools and measures, which
will contribute to production of mineral waters and increase its
export.
The paper studies and analyses current situation in mineral water
production sector as well as the factors affecting increase and
reduction of its export. It’s noted that in order to gain and maintain
competitive advantage, it’s necessary to provide continuous supply of
high quality goods with modern design, open new distribution
channels to enter new markets, carry out broad promotional activities,
organize e-commerce. Economic policy plays an important role in
protecting markets from counterfeit goods. The state also plays an
important role in attracting foreign direct investments. Stable
business environment and export oriented strategy is the basis for the
country’s economic growth.
Based on the research, the paper suggests the strategy for
improving competitiveness of Georgian mineral waters; relevant
conclusions and recommendations are provided.
Abstract: Fixed-geometry hydrodynamic journal bearings are
one of the best supporting systems for several applications of rotating
machinery. Cylindrical journal bearings present excellent loadcarrying
capacity and low manufacturing costs, but they are subjected
to the oil-film instability at high speeds. An attempt of overcoming
this instability problem has been the development of non-circular
journal bearings. This work deals with an analysis of oil-lubricated
elliptical journal bearings using the finite element method. Steadystate
and dynamic performance characteristics of elliptical bearings
are rendered by zeroth- and first-order lubrication equations obtained
through a linearized perturbation method applied on the classical
Reynolds equation. Four-node isoparametric rectangular finite
elements are employed to model the bearing thin film flow. Curves of
elliptical bearing load capacity and dynamic force coefficients are
rendered at several operating conditions. The results presented in this
work demonstrate the influence of the bearing ellipticity on its
performance at different loading conditions.
Abstract: In this paper, we introduced a gradient-based inverse
solver to obtain the missing boundary conditions based on the
readings of internal thermocouples. The results show that the method
is very sensitive to measurement errors, and becomes unstable when
small time steps are used. The artificial neural networks are shown to
be capable of capturing the whole thermal history on the run-out
table, but are not very effective in restoring the detailed behavior of
the boundary conditions. Also, they behave poorly in nonlinear cases
and where the boundary condition profile is different.
GA and PSO are more effective in finding a detailed
representation of the time-varying boundary conditions, as well as in
nonlinear cases. However, their convergence takes longer. A
variation of the basic PSO, called CRPSO, showed the best
performance among the three versions. Also, PSO proved to be
effective in handling noisy data, especially when its performance
parameters were tuned. An increase in the self-confidence parameter
was also found to be effective, as it increased the global search
capabilities of the algorithm. RPSO was the most effective variation
in dealing with noise, closely followed by CRPSO. The latter
variation is recommended for inverse heat conduction problems, as it
combines the efficiency and effectiveness required by these
problems.
Abstract: Incineration of municipal solid waste (MSW) is one of
the key scopes in the global clean energy strategy. A computational
fluid dynamics (CFD) model was established in order to reveal these
features of the combustion process in a fixed porous bed of MSW.
Transporting equations and process rate equations of the waste bed
were modeled and set up to describe the incineration process,
according to the local thermal conditions and waste property
characters. Gas phase turbulence was modeled using k-ε turbulent
model and the particle phase was modeled using the kinetic theory of
granular flow. The heterogeneous reaction rates were determined
using Arrhenius eddy dissipation and the Arrhenius-diffusion
reaction rates. The effects of primary air flow rate and temperature in
the burning process of simulated MSW are investigated
experimentally and numerically. The simulation results in bed are
accordant with experimental data well. The model provides detailed
information on burning processes in the fixed bed, which is otherwise
very difficult to obtain by conventional experimental techniques.
Abstract: In this paper, a direct power control (DPC)
strategies have been investigated in order to control a high
power AC/DC converter with time variable load. This converter
is composed of a three level three phase neutral point clamped
(NPC) converter as rectifier and an H-bridge four quadrant
current control converter. In the high power application,
controller not only must adjust the desire outputs but also
decrease the level of distortions which are injected to the network
from the converter. Regarding to this reason and nonlinearity
of the power electronic converter, the conventional controllers
cannot achieve appropriate responses. In this research, the
precise mathematical analysis has been employed to design the
appropriate controller in order to control the time variable
load. A DPC controller has been proposed and simulated using
Matlab/ Simulink. In order to verify the simulation result, a real
time simulator- OPAL-RT- has been employed. In this paper,
the dynamic response and stability of the high power NPC
with variable load has been investigated and compared with
conventional types using a real time simulator. The results proved
that the DPC controller is more stable and has more precise
outputs in comparison with conventional controller.
Abstract: This paper describes an Action Research project
which was undertaken to inform professional practice in order to
develop a newly created Centre for Student Success in the specific
context of transnational medical and nursing education in the Middle
East. The objectives were to enhance the academic performance,
persistence, integration and personal and professional development of
a multinational study body, in particular in relation to pre-clinical
medical students, and to establish a comfortable, friendly and
student-driven environment within an Irish medical university
recently established in Bahrain. The outcomes of the project resulted
in the development of a specific student success ‘signature’ for this
particular transnational higher education context.
Abstract: This study analyzes the innovative orientation of the
Croatian entrepreneurs. Innovative orientation is represented by the
perceived extent to which an entrepreneur’s product or service or
technology is new, and no other businesses offer the same product.
The sample is extracted from the GEM Croatia Adult Population
Survey dataset for the years 2003-2013. We apply descriptive
statistics, t-test, Chi-square test and logistic regression. Findings
indicate that innovative orientations vary with personal, firm, meso
and macro level variables, and between different stages in
entrepreneurship process. Significant predictors are occupation of the
entrepreneurs, size of the firm and export aspiration for both early
stage and established entrepreneurs. In addition, fear of failure,
expecting to start a new business and seeing an entrepreneurial career
as a desirable choice are predictors of innovative orientation among
early stage entrepreneurs.
Abstract: This paper attempts to define the validity domain of
LSDP (Loop Shaping Design Procedure) controller system, by
determining the suitable uncertainty region, so that linear system be
stable. Indeed the LSDP controller cannot provide stability for any
perturbed system. For this, we will use the gap metric tool that is
introduced into the control literature for studying robustness
properties of feedback systems with uncertainty. A 2nd order electric
linear system example is given to define the validity domain of LSDP
controller and effectiveness gap metric.
Abstract: Corrosion of concrete sewer pipes induced by sulfuric
acid is an acknowledged problem and a ticking time-bomb to sewer
operators. Whilst the chemical reaction of the corrosion process is
well-understood, the indirect roles of other parameters in the
corrosion process which are found in sewer environment are not
highly reflected on. This paper reports on a field studies undertaken
in Austria and United Kingdom, where the parameters of
temperature, pH, H2S and CO2 were monitored over a period of time.
The study establishes that (i) effluent temperature and pH have
similar daily pattern and peak times, when examined in minutes
scale; (ii) H2S and CO2 have an identical hourly pattern; (iii) H2S
instant or shifted relation to effluent temperature is governed by the
root mean square value of CO2.
Abstract: In urban context, urban nodes such as amenity or
hazard will certainly affect house price, while classic hedonic analysis
will employ distance variables measured from each urban nodes.
However, effects from distances to facilities on house prices generally
do not represent the true price of the property. Distance variables
measured on the same surface are suffering a problem called
multicollinearity, which is usually presented as magnitude variance
and mean value in regression, errors caused by instability. In this paper,
we provided a theoretical framework to identify and gather the data
with less bias, and also provided specific sampling method on locating
the sample region to avoid the spatial multicollinerity problem in three
distance variable’s case.
Abstract: The effect of transition metal doping on Pt/Al2O3
catalyst used in propane dehydrogenation reaction at 500°C was
studied. The preparation methods investigated were sequential
impregnation (Pt followed by the 2nd metal or the 2nd metal followed
by Pt) and co-impregnation. The metal contents of these catalysts
were fixed as the weight ratio of Pt per the 2nd metal of around 0.075.
These catalysts were characterized by N2-physisorption, TPR, COchemisorption
and NH3-TPD. It was found that the impregnated 2nd
metal had an effect upon reducibility of Pt due to its interaction with
transition metal-containing structure. This was in agreement with the
CO-chemisorption result that the presence of Pt metal, which is a
result from Pt species reduction, was decreased. The total acidity of
bimetallic catalysts is decreased but the strong acidity is slightly
increased. It was found that the stability of bimetallic catalysts
prepared by co-impregnation and sequential impregnation where the
2nd metal was impregnated before Pt were better than that of
monometallic catalyst (undoped Pt one) due to the forming of Pt sites
located on the transition metal-oxide modified surface. Among all
preparation methods, the sequential impregnation method- having Pt
impregnated before the 2nd metal gave the worst stability because this
catalyst lacked the modified Pt sites and some fraction of Pt sites was
covered by the 2nd metal.
Abstract: The development of active and stable catalysts
without noble metals for low temperature oxidation of exhaust gases
remains a significant challenge. The purpose of this study is to
determine the influence of the preparation method on the catalytic
activity of the supported copper-manganese mixed oxides in terms of
VOCs oxidation. The catalysts were prepared by impregnation of γ-
Al2O3 with copper and manganese nitrates and acetates and the
possibilities for CO, CH3OH and dimethyl ether (DME) oxidation
were evaluated using continuous flow equipment with a four-channel
isothermal stainless steel reactor. Effect of the support, Cu/Mn mole
ratio, heat treatment of the precursor and active component loading
were investigated. Highly active alumina supported Cu-Mn catalysts
for CO and VOCs oxidation were synthesized. The effect of
preparation conditions on the activity behavior of the catalysts was
discussed.
The synergetic interaction between copper and manganese species
increases the activity for complete oxidation over mixed catalysts.
Type of support, calcination temperature and active component
loading along with catalyst composition are important factors,
determining catalytic activity. Cu/Mn molar ratio of 1:5, heat
treatment at 450oC and 20 % active component loading are the best
compromise for production of active catalyst for simultaneous
combustion of CO, CH3OH and DME.
Abstract: Considering palm oil as non-drying oil owing to its
low iodine value, an attempt was taken to increase the unsaturation in
the fatty acid chains of palm oil for the preparation of alkyds. To
increase the unsaturation in the palm oil, sulphuric acid (SA) and
para-toluene sulphonic acid (PTSA) was used prior to alcoholysis for
the dehydration process. The iodine number of the oil samples was
checked for the unsaturation measurement by Wijs method. Alkyd
resin was prepared using the dehydrated palm oil by following
alcoholysis and esterification reaction. To improve the film properties
0.5wt.% multi-wall carbon nano tubes (MWCNTs) were used to
manufacture polymeric film. The properties of the resins were
characterized by various physico-chemical properties such as density,
viscosity, iodine value, saponification value, etc. Structural
elucidation was confirmed by Fourier transform of infrared
spectroscopy and proton nuclear magnetic resonance; surfaces of the
films were examined by field-emission scanning electron microscope.
In addition, pencil hardness and chemical resistivity was also
measured by using standard methods. The effect of enhancement of
the unsaturation in the fatty acid chain found significant and
motivational. The resin prepared with dehydrated palm oil showed
improved properties regarding hardness and chemical resistivity
testing. The incorporation of MWCNTs enhanced the thermal
stability and hardness of the films as well.
Abstract: This paper argues nation-building theories that
prioritize democratic governance best explain the successful postindependence
development of Botswana. Three main competing
schools of thought exist regarding the sequencing of policies that
should occur to re-build weakened or failed states. The first posits
that economic development should receive foremost attention, while
democratization and a binding sense of nationalism can wait. A
second group of experts identified constructing a sense of nationalism
among a populace is necessary first, so that the state receives popular
legitimacy and obedience that are prerequisites for development.
Botswana, though, transitioned into a multi-party democracy and
prosperous open economy due to the utilization of traditional
democratic structures, enlightened and accountable leadership, and an
educated technocratic civil service. With these political foundations
already in place when the discovery of diamonds occurred, the
resulting revenues were spent wisely on projects that grew the
economy, improved basic living standards, and attracted foreign
investment. Thus democratization preceded, and therefore provided
an accountable basis for, economic development that might otherwise
have been squandered by greedy and isolated elites to the detriment
of the greater population. Botswana was one of the poorest nations in
the world at the time of its independence in 1966, with little
infrastructure, a dependence on apartheid South Africa for trade, and
a largely subsistence economy. Over the next thirty years, though, its
economy grew the fastest of any nation in the world. The transparent
and judicious use of diamond returns is only a partial explanation, as
the government also pursued economic diversification, mass
education, and rural development in response to public needs.
As nation-building has become a project undertaken by nations
and multilateral agencies such as the United Nations and the North
Atlantic Treaty Organization, Botswana may provide best practices
that others should follow in attempting to reconstruct economically
and politically unstable states.
Abstract: The objective of countercyclical capital buffer is to
encourage banks to build up buffers in good times that can be drawn
down in bad times. The aim of the report is to assess such decisions
by banks derived from three approaches. The approaches are the
aggregate credit-to-GDP ratio, credit growth as well as banking
sector profits. The approaches are implemented for Estonia, Latvia
and Lithuania for the time period 2000-2012. The report compares
three approaches and analyses their relevance to the Baltic States by
testing the correlation between a growth in studied variables and a
growth of corresponding gaps. Methods used in the empirical part of
the report are econometric analysis as well as economic analysis,
development indicators, relative and absolute indicators and other
methods. The research outcome is a cross-Baltic comparison of two
alternative approaches to establish or release a countercyclical capital
buffer by banks and their implications for each Baltic country.
Abstract: Two finite element (FEM) models are presented in
this paper to address the random nature of the response of glued
timber structures made of wood segments with variable elastic
moduli evaluated from 3600 indentation measurements. This total
database served to create the same number of ensembles as was the
number of segments in the tested beam. Statistics of these ensembles
were then assigned to given segments of beams and the Latin
Hypercube Sampling (LHS) method was called to perform 100
simulations resulting into the ensemble of 100 deflections subjected
to statistical evaluation. Here, a detailed geometrical arrangement of
individual segments in the laminated beam was considered in the
construction of two-dimensional FEM model subjected to in fourpoint
bending to comply with the laboratory tests. Since laboratory
measurements of local elastic moduli may in general suffer from a
significant experimental error, it appears advantageous to exploit the
full scale measurements of timber beams, i.e. deflections, to improve
their prior distributions with the help of the Bayesian statistical
method. This, however, requires an efficient computational model
when simulating the laboratory tests numerically. To this end, a
simplified model based on Mindlin’s beam theory was established.
The improved posterior distributions show that the most significant
change of the Young’s modulus distribution takes place in laminae in
the most strained zones, i.e. in the top and bottom layers within the
beam center region. Posterior distributions of moduli of elasticity
were subsequently utilized in the 2D FEM model and compared with
the original simulations.