Abstract: MATCH project [1] entitle the development of an
automatic diagnosis system that aims to support treatment of colon
cancer diseases by discovering mutations that occurs to tumour
suppressor genes (TSGs) and contributes to the development of
cancerous tumours. The constitution of the system is based on a)
colon cancer clinical data and b) biological information that will be
derived by data mining techniques from genomic and proteomic
sources The core mining module will consist of the popular, well
tested hybrid feature extraction methods, and new combined
algorithms, designed especially for the project. Elements of rough
sets, evolutionary computing, cluster analysis, self-organization maps
and association rules will be used to discover the annotations
between genes, and their influence on tumours [2]-[11].
The methods used to process the data have to address their high
complexity, potential inconsistency and problems of dealing with the
missing values. They must integrate all the useful information
necessary to solve the expert's question. For this purpose, the system
has to learn from data, or be able to interactively specify by a domain
specialist, the part of the knowledge structure it needs to answer a
given query. The program should also take into account the
importance/rank of the particular parts of data it analyses, and adjusts
the used algorithms accordingly.
Abstract: This paper deals with the problem of constructing
constraints in non safe Petri Nets and then reducing the number of the
constructed constraints. In a system, assigning some linear constraints
to forbidden states is possible. Enforcing these constraints on the
system prevents it from entering these states. But there is no a
systematic method for assigning constraints to forbidden states in non
safe Petri Nets. In this paper a useful method is proposed for
constructing constraints in non safe Petri Nets. But when the number of these constraints is large enforcing them on the system may complicate the Petri Net model. So, another method is proposed for reducing the number of constructed constraints.
Abstract: Bonding has become a routine procedure in several
dental specialties – from prosthodontics to conservative dentistry and
even orthodontics. In many of these fields it is important to be able to
investigate the bonded interfaces to assess their quality. All currently
employed investigative methods are invasive, meaning that samples
are destroyed in the testing procedure and cannot be used again. We
have investigated the interface between human enamel and bonded
ceramic brackets non-invasively, introducing a combination of new
investigative methods – optical coherence tomography (OCT),
fluorescence OCT and confocal microscopy (CM). Brackets were
conventionally bonded on conditioned buccal surfaces of teeth. The
bonding was assessed using these methods. Three dimensional
reconstructions of the detected material defects were developed using
manual and semi-automatic segmentation. The results clearly prove
that OCT, fluorescence OCT and CM are useful in orthodontic
bonding investigations.
Abstract: Data mining uses a variety of techniques each of which is useful for some particular task. It is important to have a deep understanding of each technique and be able to perform sophisticated analysis. In this article we describe a tool built to simulate a variation of the Kohonen network to perform unsupervised clustering and support the entire data mining process up to results visualization. A graphical representation helps the user to find out a strategy to optmize classification by adding, moving or delete a neuron in order to change the number of classes. The tool is also able to automatically suggest a strategy for number of classes optimization.The tool is used to classify macroeconomic data that report the most developed countries? import and export. It is possible to classify the countries based on their economic behaviour and use an ad hoc tool to characterize the commercial behaviour of a country in a selected class from the analysis of positive and negative features that contribute to classes formation.
Abstract: A Comparison and evaluation of the different
condition monitoring (CM) techniques was applied experimentally
on RC e.g. Dynamic cylinder pressure and crankshaft Instantaneous
Angular Speed (IAS), for the detection and diagnosis of valve faults
in a two - stage reciprocating compressor for a programme of
condition monitoring which can successfully detect and diagnose a
fault in machine. Leakage in the valve plate was introduced
experimentally into a two-stage reciprocating compressor. The effect
of the faults on compressor performance was monitored and the
differences with the normal, healthy performance noted as a fault
signature been used for the detection and diagnosis of faults.
The paper concludes with what is considered to be a unique
approach to condition monitoring. First, each of the two most useful
techniques is used to produce a Truth Table which details the
circumstances in which each method can be used to detect and
diagnose a fault. The two Truth Tables are then combined into a
single Decision Table to provide a unique and reliable method of
detection and diagnosis of each of the individual faults introduced
into the compressor. This gives accurate diagnosis of compressor
faults.
Abstract: Heat-inducible gene expression vectors are useful for hyperthermia-induced cancer gene therapy, because the combination
of hyperthermia and gene therapy can considerably improve the therapeutic effects. In the present study, we developed an enhanced
heat-inducible transgene expression system in which a heat-shock
protein (HSP) promoter and tetracycline-responsive transactivator
were combined. When the transactivator plasmid containing the
tetracycline-responsive transactivator gene was co-transfected with
the reporter gene expression plasmid, a high level of heat-induced gene expression was observed compared with that using the HSP
promoter without the transactivator. In vitro evaluation of the
therapeutic effect using HeLa cells showed that heat-induced therapeutic gene expression caused cell death in a high percentage of
these cells, indicating that this strategy is promising for cancer gene therapy.
Abstract: This study examines the possibility to apply the theory of multidimensional accounting (momentum accounting) in a Brazilian Navy-s Services Provider Military Organization (Organização Militar Prestadora de Serviços - OMPS). In general, the core of the said theory is the fact that Accounting does not recognize the inertia of transactions occurring in an entity, and that occur repeatedly in some cases, regardless of the implementation of new actions by its managers. The study evaluates the possibility of greater use of information recorded in the financial statements of the unit of analysis, within the strategic decisions of the organization. As a research strategy, we adopted the case study. The results infer that it is possible to use the theory in the context of a multidimensional OMPS, promoting useful information for decision-making and thereby contributing to the strengthening of the necessary alignment of its administration with the current desires of the Brazilian society.
Abstract: Work stress causes the organizational work-life
imbalance of employees. Because of this imbalance, workers perform
with lower effort to finish assignments and thus an organization will
experience reduced productivity. In order to investigate the problem
of an organizational work-life imbalance, this qualitative case study
focuses on an organizational work-life imbalance among Thai
software developers in a German-owned company in Chiang Mai,
Thailand. In terms of knowledge management, fishbone diagram is
useful analysis tool to investigate the root causes of an organizational
work-life imbalance systematically in focus-group discussions.
Furthermore, fishbone diagram shows the relationship between
causes and effects clearly. It was found that an organizational worklife
imbalance among Thai software developers is influenced by
management team, work environment, and information tools used in
the company over time.
Abstract: The contamination of 15 ground water resources
of a selected region earmarked for the emergency supply
of population has been monitored. The resources have been selected
on the basis of previous assessment of natural conditions
and the exploitation of territory in their surroundings and infiltration
area. Two resources out of 15 have been excluded from further
exploitation, because they have not met some of the 72 assessed
hygienic indicators of extended analysis. The remaining 13 resources
have been the subject of health risk analysis in relation
to the contamination by arsenic, lead, cadmium, mercury, nickel and
manganese. The risk analysis proved that all 13 resources meet
health standards with regard to the above mentioned purposefully
selected elements and may thus be included into crisis plans. Water
quality of ground resources may be assessed in the same way
with regard to other contaminants.
Abstract: The photonic component industry is a highly
innovative industry with a large value chain. In order to ensure the
growth of the industry much effort must be devoted to road mapping
activities. In such activities demand and price evolution forecasting
tools can prove quite useful in order to help in the roadmap
refinement and update process. This paper attempts to provide useful
guidelines in roadmapping of optical components and considers two
models based on diffusion theory and the extended learning curve for
demand and price evolution forecasting.
Abstract: Hierarchical high-level PNs (HHPNs) with time
versions are a useful tool to model systems in a variety of application
domains, ranging from logistics to complex workflows. This paper
addresses an application domain which is receiving more and more
attention: procedure that arranges the final inpatient charge in
payment-s office and their management. We shall prove that Petri net
based analysis is able to improve the delays during the procedure, in
order that inpatient charges could be more reliable and on time.
Abstract: In this paper, a new approach for target recognition based on the Empirical mode decomposition (EMD) algorithm of Huang etal. [11] and the energy tracking operator of Teager [13]-[14] is introduced. The conjunction of these two methods is called Teager-Huang analysis. This approach is well suited for nonstationary signals analysis. The impulse response (IR) of target is first band pass filtered into subsignals (components) called Intrinsic mode functions (IMFs) with well defined Instantaneous frequency (IF) and Instantaneous amplitude (IA). Each IMF is a zero-mean AM-FM component. In second step, the energy of each IMF is tracked using the Teager energy operator (TEO). IF and IA, useful to describe the time-varying characteristics of the signal, are estimated using the Energy separation algorithm (ESA) algorithm of Maragos et al .[16]-[17]. In third step, a set of features such as skewness and kurtosis are extracted from the IF, IA and IMF energy functions. The Teager-Huang analysis is tested on set of synthetic IRs of Sonar targets with different physical characteristics (density, velocity, shape,? ). PCA is first applied to features to discriminate between manufactured and natural targets. The manufactured patterns are classified into spheres and cylinders. One hundred percent of correct recognition is achieved with twenty three echoes where sixteen IRs, used for training, are free noise and seven IRs, used for testing phase, are corrupted with white Gaussian noise.
Abstract: The behavior of Radial Basis Function (RBF) Networks greatly depends on how the center points of the basis functions are selected. In this work we investigate the use of instance reduction techniques, originally developed to reduce the storage requirements of instance based learners, for this purpose. Five Instance-Based Reduction Techniques were used to determine the set of center points, and RBF networks were trained using these sets of centers. The performance of the RBF networks is studied in terms of classification accuracy and training time. The results obtained were compared with two Radial Basis Function Networks: RBF networks that use all instances of the training set as center points (RBF-ALL) and Probabilistic Neural Networks (PNN). The former achieves high classification accuracies and the latter requires smaller training time. Results showed that RBF networks trained using sets of centers located by noise-filtering techniques (ALLKNN and ENN) rather than pure reduction techniques produce the best results in terms of classification accuracy. The results show that these networks require smaller training time than that of RBF-ALL and higher classification accuracy than that of PNN. Thus, using ALLKNN and ENN to select center points gives better combination of classification accuracy and training time. Our experiments also show that using the reduced sets to train the networks is beneficial especially in the presence of noise in the original training sets.
Abstract: A phorbol-12-myristate-13-acetate (TPA) is a synthetic analogue of phorbol ester (PE), a natural toxic compound of Euphorbiaceae plant. The oil extracted from plants of this family is useful source for primarily biofuel. However this oil might also be used as a foodstuff due to its significant nutrition content. The limitations for utilizing the oil as a foodstuff are mainly due to a toxicity of PE. Currently, a majority of PE detoxification processes are expensive as include multi steps alcohol extraction sequence.
Ozone is considered as a strong oxidative agent. It reacts with PE by attacking the carbon-carbon double bond of PE. This modification of PE molecular structure yields a non toxic ester with high lipid content.
This report presents data on development of simple and cheap PE detoxification process with water application as a buffer and ozone as reactive component. The core of this new technique is an application for a new microscale plasma unit to ozone production and the technology permits ozone injection to the water-TPA mixture in form of microbubbles.
The efficacy of a heterogeneous process depends on the diffusion coefficient which can be controlled by contact time and interfacial area. The low velocity of rising microbubbles and high surface to volume ratio allow efficient mass transfer to be achieved during the process. Direct injection of ozone is the most efficient way to process with such highly reactive and short lived chemical.
Data on the plasma unit behavior are presented and the influence of gas oscillation technology on the microbubble production mechanism has been discussed. Data on overall process efficacy for TPA degradation is shown.
Abstract: Estimation time and cost of work completion in a
project and follow up them during execution are contributors to
success or fail of a project, and is very important for project
management team. Delivering on time and within budgeted cost
needs to well managing and controlling the projects. To dealing with
complex task of controlling and modifying the baseline project
schedule during execution, earned value management systems have
been set up and widely used to measure and communicate the real
physical progress of a project. But it often fails to predict the total
duration of the project. In this paper data mining techniques is used
predicting the total project duration in term of Time Estimate At
Completion-EAC (t). For this purpose, we have used a project with
90 activities, it has updated day by day. Then, it is used regular
indexes in literature and applied Earned Duration Method to
calculate time estimate at completion and set these as input data for
prediction and specifying the major parameters among them using
Clem software. By using data mining, the effective parameters on
EAC and the relationship between them could be extracted and it is
very useful to manage a project with minimum delay risks. As we
state, this could be a simple, safe and applicable method in prediction
the completion time of a project during execution.
Abstract: Earth reinforcing techniques have become useful and economical to solve problems related to difficult grounds and provide satisfactory foundation performance. In this context, this paper uses radial basis function neural network (RBFNN) for predicting the bearing pressure of strip footing on reinforced granular bed overlying weak soil. The inputs for the neural network models included plate width, thickness of granular bed and number of layers of reinforcements, settlement ratio, water content, dry density, cohesion and angle of friction. The results indicated that RBFNN model exhibited more than 84 % prediction accuracy, thereby demonstrating its application in a geotechnical problem.
Abstract: Mobile Ad hoc networks (MANETs) are collections
of wireless mobile nodes dynamically reconfiguring and collectively
forming a temporary network. These types of networks assume
existence of no fixed infrastructure and are often useful in battle-field
tactical operations or emergency search-and-rescue type of
operations where fixed infrastructure is neither feasible nor practical.
They also find use in ad hoc conferences, campus networks and
commercial recreational applications carrying multimedia traffic. All
of the above applications of MANETs require guaranteed levels of
performance as experienced by the end-user. This paper focuses on
key challenges in provisioning predetermined levels of such Quality
of Service (QoS). It also identifies functional areas where QoS
models are currently defined and used. Evolving functional areas
where performance and QoS provisioning may be applied are also
identified and some suggestions are provided for further research in
this area. Although each of the above functional areas have been
discussed separately in recent research studies, since these QoS
functional areas are highly correlated and interdependent, a
comprehensive and comparative analysis of these areas and their
interrelationships is desired. In this paper we have attempted to
provide such an overview.
Abstract: This paper details the application of a genetic
programming framework for induction of useful classification rules
from a database of income statements, balance sheets, and cash flow
statements for North American public companies. Potentially
interesting classification rules are discovered. Anomalies in the
discovery process merit further investigation of the application of
genetic programming to the dataset for the problem domain.
Abstract: The goal of data mining algorithms is to discover
useful information embedded in large databases. One of the most
important data mining problems is discovery of frequently occurring
patterns in sequential data. In a multidimensional sequence each
event depends on more than one dimension. The search space is quite
large and the serial algorithms are not scalable for very large
datasets. To address this, it is necessary to study scalable parallel
implementations of sequence mining algorithms.
In this paper, we present a model for multidimensional sequence
and describe a parallel algorithm based on data parallelism.
Simulation experiments show good load balancing and scalable and
acceptable speedup over different processors and problem sizes and
demonstrate that our approach can works efficiently in a real parallel
computing environment.
Abstract: A research project dealing with the phytoremediation
of a soil polluted by some heavy metals is currently running. The
case study is represented by a mining area in Hamedan province in
the central west part of Iran. The potential of phytoextraction and
phytostabilization of plants was evaluated considering the
concentration of heavy metals in the plant tissues and also the
bioconcentration factor (BCF) and the translocation factor (TF). Also
the several established criteria were applied to define
hyperaccumulator plants in the studied area. Results showed that
none of the collected plant species were suitable for phytoextraction
of Cu, Zn, Fe and Mn, but among the plants, Euphorbia macroclada
was the most efficient in phytostabilization of Cu and Fe, while,
Ziziphora clinopodioides, Cousinia sp. and Chenopodium botrys
were the most suitable for phytostabilization of Zn and Chondrila
juncea and Stipa barbata had the potential for phytostabilization of
Mn. Using the most common criterion, Euphorbia macroclada and
Verbascum speciosum were Fe hyperaccumulator plants. Present
study showed that native plant species growing on contaminated sites
may have the potential for phytoremediation.