Abstract: Mammalian genomes contain large number of
retroelements (SINEs, LINEs and LTRs) which could affect
expression of protein coding genes through associated transcription
factor binding sites (TFBS). Activity of the retroelement-associated
TFBS in many genes is confirmed experimentally but their global
functional impact remains unclear. Human SINEs (Alu repeats) and
mouse SINEs (B1 and B2 repeats) are known to be clustered in GCrich
gene rich genome segments consistent with the view that they
can contribute to regulation of gene expression. We have shown
earlier that Alu are involved in formation of cis-regulatory modules
(clusters of TFBS) in human promoters, and other authors reported
that Alu located near promoter CpG islands have an increased
frequency of CpG dinucleotides suggesting that these Alu are
undermethylated. Human Alu and mouse B1/B2 elements have an
internal bipartite promoter for RNA polymerase III containing
conserved sequence motif called B-box which can bind basal
transcription complex TFIIIC. It has been recently shown that TFIIIC
binding to B-box leads to formation of a boundary which limits
spread of repressive chromatin modifications in S. pombe. SINEassociated
B-boxes may have similar function but conservation of
TFIIIC binding sites in SINEs located near mammalian promoters
has not been studied earlier. Here we analysed abundance and
distribution of retroelements (SINEs, LINEs and LTRs) in annotated
sequences of the Database of mammalian transcription start sites
(DBTSS). Fractions of SINEs in human and mouse promoters are
slightly lower than in all genome but >40% of human and mouse
promoters contain Alu or B1/B2 elements within -1000 to +200 bp
interval relative to transcription start site (TSS). Most of these SINEs
is associated with distal segments of promoters (-1000 to -200 bp
relative to TSS) indicating that their insertion at distances >200 bp
upstream of TSS is tolerated during evolution. Distribution of SINEs
in promoters correlates negatively with the distribution of CpG
sequences. Using analysis of abundance of 12-mer motifs from the
B1 and Alu consensus sequences in genome and DBTSS it has been
confirmed that some subsegments of Alu and B1 elements are poorly
conserved which depends in part on the presence of CpG
dinucleotides. One of these CpG-containing subsegments in B1
elements overlaps with SINE-associated B-box and it shows better
conservation in DBTSS compared to genomic sequences. It has been
also studied conservation in DBTSS and genome of the B-box
containing segments of old (AluJ, AluS) and young (AluY) Alu
repeats and found that CpG sequence of the B-box of old Alu is
better conserved in DBTSS than in genome. This indicates that Bbox-
associated CpGs in promoters are better protected from
methylation and mutation than B-box-associated CpGs in genomic
SINEs. These results are consistent with the view that potential
TFIIIC binding motifs in SINEs associated with human and mouse
promoters may be functionally important. These motifs may protect
promoters from repressive histone modifications which spread from
adjacent sequences. This can potentially explain well known
clustering of SINEs in GC-rich gene rich genome compartments and
existence of unmethylated CpG islands.
Abstract: The paper presents an on-line recognition machine
(RM) for continuous/isolated, dynamic and static gestures that arise
in Flight Deck Officer (FDO) training. RM is based on generic pattern
recognition framework. Gestures are represented as templates using
summary statistics. The proposed recognition algorithm exploits temporal
and spatial characteristics of gestures via dynamic programming
and Markovian process. The algorithm predicts corresponding index
of incremental input data in the templates in an on-line mode.
Accumulated consistency in the sequence of prediction provides a
similarity measurement (Score) between input data and the templates.
The algorithm provides an intuitive mechanism for automatic detection
of start/end frames of continuous gestures. In the present paper,
we consider isolated gestures. The performance of RM is evaluated
using four datasets - artificial (W TTest), hand motion (Yang) and
FDO (tracker, vision-based ). RM achieves comparable results which
are in agreement with other on-line and off-line algorithms such as
hidden Markov model (HMM) and dynamic time warping (DTW).
The proposed algorithm has the additional advantage of providing
timely feedback for training purposes.
Abstract: In this paper we present a study of the impact of connection schemes on the performance of iterative decoding of Generalized Parallel Concatenated block (GPCB) constructed from one step majority logic decodable (OSMLD) codes and we propose a new connection scheme for decoding them. All iterative decoding connection schemes use a soft-input soft-output threshold decoding algorithm as a component decoder. Numerical result for GPCB codes transmitted over Additive White Gaussian Noise (AWGN) channel are provided. It will show that the proposed scheme is better than Hagenauer-s scheme and Lucas-s scheme [1] and slightly better than the Pyndiah-s scheme.
Abstract: The ongoing effort to develop an in-house
compressible solver with multi-disciplinary physics is presented in
this paper. Basic compressible solver combined with IBM technique
provides us an effective numerical tool able to tackle the physics
phenomena and especially physic phenomena involved in Solid
Rocket Motors (SRMs). Main principles are introduced step by step
describing its implementation. This paper sheds light on the whole
potentiality of our proposed numerical model and we strongly believe
a way to introduce multi-physics mechanisms strongly coupled is
opened to ablation in nozzle, fluid/structure interaction and burning
propellant surface with time.
Abstract: This paper proposes the use of metrics in design space exploration that highlight where in the structure of the model and at what point in the behaviour, prevention is needed against transient faults. Previous approaches to tackle transient faults focused on recovery after detection. Almost no research has been directed towards preventive measures. But in real-time systems, hard deadlines are performance requirements that absolutely must be met and a missed deadline constitutes an erroneous action and a possible system failure. This paper proposes the use of metrics to assess the system design to flag where transient faults may have significant impact. These tools then allow the design to be changed to minimize that impact, and they also flag where particular design techniques – such as coding of communications or memories – need to be applied in later stages of design.
Abstract: Unmanned Aerial Vehicles (UAVs) have gained tremendous importance, in both Military and Civil, during first decade of this century. In a UAV, onboard computer (autopilot) autonomously controls the flight and navigation of the aircraft. Based on the aircraft role and flight envelope, basic to complex and sophisticated controllers are used to stabilize the aircraft flight parameters. These controllers constitute the autopilot system for UAVs. The autopilot systems, most commonly, provide lateral and longitudinal control through Proportional-Integral-Derivative (PID) controllers or Phase-lead or Lag Compensators. Various techniques are commonly used to ‘tune’ gains of these controllers. Some techniques used are, in-flight step-by-step tuning, software-in-loop or hardware-in-loop tuning methods. Subsequently, numerous in-flight tests are required to actually ‘fine-tune’ these gains. However, an optimization-based tuning of these PID controllers or compensators, as presented in this paper, can greatly minimize the requirement of in-flight ‘tuning’ and substantially reduce the risks and cost involved in flight-testing.
Abstract: This paper aims to present the design, fabrication and test of a novel piezoelectric actuated, check-valves embedded micropump having the advantages of miniature size, light weight and low power consumption. This device is designed to pump gases and liquids with the capability of performing the self-priming and bubble-tolerant work mode by maximizing the stroke volume of the membrane as well as the compression ratio via minimization of the dead volume of the micropump chamber and channel. By experiment apparatus setup, we can get the real-time values of the flow rate of micropump, the displacement of the piezoelectric actuator and the deformation of the check valve, simultaneously. The micropump with check valve 0.4 mm in thickness obtained higher output performance under the sinusoidal waveform of 120 Vpp. The micropump achieved the maximum pumping rates of 42.2 ml/min and back pressure of 14.0 kPa at the corresponding frequency of 28 and 20 Hz. The presented micropump is able to pump gases with a pumping rate of 196 ml/min at operating frequencies of 280 Hz under the sinusoidal waveform of 120 Vpp.
Abstract: Integrins are a large family of multidomain α/β cell
signaling receptors. Some integrins contain an additional inserted I
domain, whose earliest expression appears to be with the chordates,
since they are observed in the urochordates Ciona intestinalis (vase
tunicate) and Halocynthia roretzi (sea pineapple), but not in integrins
of earlier diverging species. The domain-s presence is viewed as a
hallmark of integrins of higher metazoans, however in vertebrates,
there are clearly three structurally-different classes: integrins without
I domains, and two groups of integrins with I domains but separable
by the presence or absence of an additional αC helix. For example,
the αI domains in collagen-binding integrins from Osteichthyes
(bony fish) and all higher vertebrates contain the specific αC helix,
whereas the αI domains in non-collagen binding integrins from
vertebrates and the αI domains from earlier diverging urochordate
integrins, i.e. tunicates, do not. Unfortunately, within the early
chordates, there is an evolutionary gap due to extinctions between the
tunicates and cartilaginous fish. This, coupled with a knowledge gap
due to the lack of complete genomic data from surviving species,
means that the origin of collagen-binding αC-containing αI domains
remains unknown. Here, we analyzed two available genomes from
Callorhinchus milii (ghost shark/elephant shark; Chondrichthyes –
cartilaginous fish) and Petromyzon marinus (sea lamprey;
Agnathostomata), and several available Expression Sequence Tags
from two Chondrichthyes species: Raja erinacea (little skate) and
Squalus acanthias (dogfish shark); and Eptatretus burgeri (inshore
hagfish; Agnathostomata), which evolutionary reside between the
urochordates and osteichthyes. In P. marinus, we observed several
fragments coding for the αC-containing αI domain, allowing us to
shed more light on the evolution of the collagen-binding integrins.
Abstract: The aim of this work is to present a multi-objective optimization method to find maximum efficiency kinematics for a flapping wing unmanned aerial vehicle. We restrained our study to rectangular wings with the same profile along the span and to harmonic dihedral motion. It is assumed that the birdlike aerial vehicle (whose span and surface area were fixed respectively to 1m and 0.15m2) is in horizontal mechanically balanced motion at fixed speed. We used two flight physics models to describe the vehicle aerodynamic performances, namely DeLaurier-s model, which has been used in many studies dealing with flapping wings, and the model proposed by Dae-Kwan et al. Then, a constrained multi-objective optimization of the propulsive efficiency is performed using a recent evolutionary multi-objective algorithm called є-MOEA. Firstly, we show that feasible solutions (i.e. solutions that fulfil the imposed constraints) can be obtained using Dae-Kwan et al.-s model. Secondly, we highlight that a single objective optimization approach (weighted sum method for example) can also give optimal solutions as good as the multi-objective one which nevertheless offers the advantage of directly generating the set of the best trade-offs. Finally, we show that the DeLaurier-s model does not yield feasible solutions.
Abstract: We present a hardware oriented method for real-time
measurements of object-s position in video. The targeted application
area is light spots used as references for robotic navigation. Different
algorithms for dynamic thresholding are explored in combination
with component labeling and Center Of Gravity (COG) for highest
possible precision versus Signal-to-Noise Ratio (SNR). This method
was developed with a low hardware cost in focus having only one
convolution operation required for preprocessing of data.
Abstract: Microplasma welding is a less expensive alternative to
laser welding in dental technology. The aim of the study was to
highlight discontinuities present in the microplasma welded joints of
dental base metal alloys by visual analysis. Five base metal alloys
designated for fixed prostheses manufacture were selected for the
experiments. Using these plates, preliminary tests were conducted by
microplasma welding in butt joint configuration, without filler
material, bilaterally and with filler material, proper for each base
metal. Macroscopic visual inspection was performed to assess
carefully the irregularities in the welds. Electron microscopy allowed
detection of discontinuities that are not visible to the eye and
revealing details regarding location, trajectory, morphology and size
of discontinuities. Supplementing visual control with microscopic
analysis allows to detect small discontinuities, which escapes the
macroscopic control and to make a detailed study of the weld.
Abstract: Polypropylene blended with natural oil and pigment additives has been studied. Different formulations for each compound were made into polybag used for cultivation of oil palm seedlings for strength and mechanical properties studies. One group of sample was exposed under normal sunlight to initiate degradation and another group of sample was placed under shaded area for five months. All samples were tested for tensile strength to determine the degradation effects. The tensile strength of directly exposed sunlight samples and shaded area showed up to 50% and 25% degradation respectively. However, similar reduction of Young’s modulus for all samples was found for both exposures. Structural investigations were done using FTIR to detect deformation. The natural additives that were used in the studies were all natural and environmental friendly
Abstract: Islamic institutions in Malaysia play a variety of
socioeconomic roles such as poverty alleviation. To perform this role,
these institutions face a major task in identifying the poverty group.
Most of these institutions measure and operationalize poverty from
the monetary perspective using variables such as income, expenditure
or consumption. In practice, most Islamic institutions in Malaysia use
the monetary approach in measuring poverty through the
conventional Poverty Line Income (PLI) method and recently, the
had al kifayah (HAK) method using total necessities of a household
from an Islamic perspective. The objective of this paper is to present
the PLI and also the HAK method. This micro-data study would
highlight the similarities and differences of both the methods.A
survey aided by a structured questionnaire was carried out on 260
selected head of households in the state of Selangor. The paper
highlights several demographic factors that are associated with the
three monetary indicators in the study, namely income, PLI and
HAK. In addition, the study found that these monetary variables are
significantly related with each other.
Abstract: Together with the industrialization, women began to
be included in business life by peeling off of the tasks given them by
society and they have become a factor of production creating value in
economic and social sense. Thus, women have taken place in the
labor market, majority of which has been formed by men. In this
study, the experiences of women entrepreneurs, who succeed in
business activities, will be analyzed. By the study, current state of the
women entrepreneurs in the labor market of Turkey will be put down,
as a result of interferences obtained from the shared experiences of
women entrepreneurs. Findings obtained at the end of the study are
thought to light the way of future studies for increasing women
entrepreneurship.
Abstract: Increasing user comfort and reducing operation costs
have always been primary objectives of lighting control strategies in a
building. This paper proposes an architecture of the lighting control
system for a daylit office. The system consists of the lighting
controller, A/D & D/A converter, dimmable LED lights, and the
lighting management software. Verification tests are conducted using
the proposed system specialized for the interior lighting of a open-plan
office. The results showed the proposed architecture of the lighting
system would improve the overall system reliability, lower the system
cost, and provide ease of installation and maintenance.
Abstract: The paper explores the development of an optimization of method and apparatus for retrieving extended high dynamic range from digital negative image. Architectural photo imaging can benefit from high dynamic range imaging (HDRI) technique for preserving and presenting sufficient luminance in the shadow and highlight clipping image areas. The HDRI technique that requires multiple exposure images as the source of HDRI rendering may not be effective in terms of time efficiency during the acquisition process and post-processing stage, considering it has numerous potential imaging variables and technical limitations during the multiple exposure process. This paper explores an experimental method and apparatus that aims to expand the dynamic range from digital negative image in HDRI environment. The method and apparatus explored is based on a single source of RAW image acquisition for the use of HDRI post-processing. It will cater the optimization in order to avoid and minimize the conventional HDRI photographic errors caused by different physical conditions during the photographing process and the misalignment of multiple exposed image sequences. The study observes the characteristics and capabilities of RAW image format as digital negative used for the retrieval of extended high dynamic range process in HDRI environment.
Abstract: This paper addresses the fundamental requirements for
starting an online business. It covers the process of ideation,
conceptualization, formulation, and implementation of new venture
ideas on the Web. Using Facebook as an illustrative example, we learn
how to turn an idea into a successful electronic business and to execute
a business plan with IT skills, management expertise, a good
entrepreneurial attitude, and an understanding of Internet culture. The
personality traits and characteristics of a successful e-commerce
entrepreneur are discussed with reference to Facebook-s founder,
Mark Zuckerberg. Facebook is a social and e-commerce success. It
provides a trusted environment of which participants can conduct
business with social experience. People are able to discuss products
before, during the after the sale within the Facebook environment. The
paper also highlights the challenges and opportunities for e-commerce
entrepreneurial startups to go public and of entering the China market.
Abstract: The design of a landing gear is one of the fundamental aspects of aircraft design. The need for a light weight, high strength, and stiffness characteristics coupled with techno economic feasibility are a key to the acceptability of any landing gear construction. In this paper, an approach for analyzing two different designed landing gears for an unmanned aircraft vehicle (UAV) using advanced CAE techniques will be applied. Different landing conditions have been considered for both models. The maximum principle stresses for each model along with the factor of safety are calculated for every loading condition. A conclusion is drawing about better geometry.
Abstract: Solar power plants(SPPs) have shown a lot of good outcomes
in providing a various functions depending on industrial expectations by
deploying ad-hoc networking with helps of light loaded and battery powered
sensor nodes. In particular, it is strongly requested to develop an algorithm to
deriver the sensing data from the end node of solar power plants to the sink node
on time. In this paper, based on the above observation we have proposed an
IEEE802.15.4 based self routing scheme for solar power plants. The proposed
beacon based priority routing Algorithm (BPRA) scheme utilizes beacon
periods in sending message with embedding the high priority data and thus
provides high quality of service(QoS) in the given criteria. The performance
measures are the packet Throughput, delivery, latency, total energy
consumption. Simulation results under TinyOS Simulator(TOSSIM) have
shown the proposed scheme outcome the conventional Ad hoc On-Demand
Distance Vector(AODV) Routing in solar power plants.
Abstract: This paper describes the development of a fully
automated measurement software for antenna radiation pattern
measurements in a Compact Antenna Test Range (CATR). The
CATR has a frequency range from 2-40 GHz and the measurement
hardware includes a Network Analyzer for transmitting and
Receiving the microwave signal and a Positioner controller to control
the motion of the Styrofoam column. The measurement process
includes Calibration of CATR with a Standard Gain Horn (SGH)
antenna followed by Gain versus angle measurement of the Antenna
under test (AUT). The software is designed to control a variety of
microwave transmitter / receiver and two axis Positioner controllers
through the standard General Purpose interface bus (GPIB) interface.
Addition of new Network Analyzers is supported through a slight
modification of hardware control module. Time-domain gating is
implemented to remove the unwanted signals and get the isolated
response of AUT. The gated response of the AUT is compared with
the calibration data in the frequency domain to obtain the desired
results. The data acquisition and processing is implemented in
Agilent VEE and Matlab. A variety of experimental measurements
with SGH antennas were performed to validate the accuracy of
software. A comparison of results with existing commercial
softwares is presented and the measured results are found to be
within .2 dBm.