Abstract: High Performance Liquid Chromatography (HPLC)
method was developed and validated for simultaneous estimation of
6-Gingerol(6G) and 6-Shogaol(6S) in joint pain relief gel containing
ginger extract. The chromatographic separation was achieved by
using C18 column, 150 x 4.6mm i.d., 5μ Luna, mobile phase
containing acetonitrile and water (gradient elution). The flow rate
was 1.0 ml/min and the absorbance was monitored at 282 nm. The
proposed method was validated in terms of the analytical parameters
such as specificity, accuracy, precision, linearity, range, limit of
detection (LOD), limit of quantification (LOQ), and determined
based on the International Conference on Harmonization (ICH)
guidelines. The linearity ranges of 6G and 6S were obtained over 20-
60 and 6-18 μg/ml respectively. Good linearity was observed over the
above-mentioned range with linear regression equation Y= 11016x-
23778 for 6G and Y = 19276x-19604 for 6S (x is concentration of
analytes in μg/ml and Y is peak area). The value of correlation
coefficient was found to be 0.9994 for both markers. The limit of
detection (LOD) and limit of quantification (LOQ) for 6G were
0.8567 and 2.8555 μg/ml and for 6S were 0.3672 and 1.2238 μg/ml
respectively. The recovery range for 6G and 6S were found to be
91.57 to 102.36 % and 84.73 to 92.85 % for all three spiked levels.
The RSD values from repeated extractions for 6G and 6S were 3.43
and 3.09% respectively. The validation of developed method on
precision, accuracy, specificity, linearity, and range were also
performed with well-accepted results.
Abstract: The paper will focus on the strategic development
deriving from the evolution of the traditional courtyard spatial
organization towards a new, contemporary sustainable way of living.
New sustainable approaches that engulf the social issues, the notion
of place, the understanding of weather architecture blended together
with the bioclimatic behavior will be seen through a series of
experimental case studies in the island of Cyprus, inspired and
originated from its traditional wisdom, ranging from small scale of
living to urban interventions. Weather and nature will be seen as co-architectural authors with
architects. Furthermore, the building will be seen not as an object but
rather as a vessel of human activities. This will further enhance the
notion of merging the material and immaterial, the built and unbuilt,
subject-human, and the object-building. This eventually will enable
to generate the discussion of the understanding of the building in
relation to the place and its inhabitants, where the human topography
is more important than the material topography. The specificities of
the divided island and the dealing with sites that are in vicinity with
the diving Green Line will further trigger explorations dealing with
the regeneration issues and the social sustainability offering
unprecedented opportunities for innovative sustainable ways of
living. Opening up a discourse with premises of weather-nature, materialimmaterial,
human-material topographies in relation to the contested
sites of the borders will lead us to develop innovative strategies for a
profound, both technical and social sustainability, which fruitfully
yields to innovative living built environments, responding to the ever
changing environmental and social needs. As a starting point, a case study in Kaimakli in Nicosia, a
refurbishment with an extension of a traditional house, already
engulfs all the traditional/ vernacular wisdom of the bioclimatic
architecture. The project focusses on the direct and quite obvious
bioclimatic features such as south orientation and cross ventilation.
Furthermore, it tries to reinvent the adaptation of these parameters in
order to turn the whole house to a contemporary living environment.
In order to succeed this, evolutions of traditional architectural
elements and spatial conditions are integrated in a way that does not
only respond to some certain weather conditions, but they integrate
and blend the weather within the built environment. A series of
innovations aiming at maximum flexibility is proposed. The house
can finally be transformed into a winter enclosure, while for the most
part of the year it turns into a ‘camping’ living environment. Parallel to experimental interventions in existing traditional units,
we will proceed examining the implementation of the same
developed methodology in designing living units and complexes.
Malleable courtyard organizations that attempt to blend the
traditional wisdom with the contemporary needs for living, the
weather and nature with the built environment will be seen tested in
both horizontal and vertical developments. Social activities are seen as directly affected and forged by the
weather conditions thus generating a new social identity of people where people are directly involved and interacting with the weather.
The human actions and interaction with the built, material
environment in order to respond to weather will be seen as the result
of balancing the social with the technological sustainability, the
immaterial, and the material aspects of the living environment.
Abstract: Electrical Muscle Stimulation (EMS) has been
introduced and globally gained increasing attention on its usefulness.
Continuous application of EMS may lead to the increment of muscle
mass and indirectly will increase the strength. This study can be used
as an alternative to help people especially those living a sedentary
lifestyle to improve their muscle activity without having to go
through a heavy workout session. Therefore, this study intended to
investigate the effectiveness of EMS training program in 5 weeks
interventions towards male body composition. It was a quasiexperimental
design, held at the Impulse Studio Bangsar, which
examined the effects of EMS training towards skeletal muscle mass
among the subjects. Fifteen subjects (n = 15) were selected to assist
in this study. The demographic data showed that, the average age of
the subjects was 43.07 years old ± 9.90, height (173.4 cm ± 9.09) and
weight was (85.79 kg ± 18.07). Results showed that there was a
significant difference on the skeletal muscle mass (p = 0.01 < 0.05),
upper body (p = 0.01 < 0.05) and lower body (p = 0.00 < 0.05).
Therefore, the null hypothesis has been rejected in this study. As a
conclusion, the application of EMS towards body composition can
increase the muscle size and strength. This method has been proven
to be able to improve athlete strength and thus, may be implemented
in the sports science area of knowledge.
Abstract: This paper presents a case study of using STATCOM to enhance the performance of Al-Qatraneh 33-kV transmission line. The location of the STATCOM was identified by maintaining minimum voltage drops at the 110 load nodes. The transmission line and the 110 load nodes have been modeled by MATLAB/Simulink. The suggested STATCOM and its location will increase the transmission capability of this transmission line and overcome the overload expected in the year 2020. The annual percentage loading rise has been considered as 14.35%. A graphical representation of the line-to-line voltages and the voltage drops at different load nodes is illustrated.
Abstract: The education sector is constantly faced with rapid
changes in technologies in terms of ensuring that the curriculum is up
to date and in terms of making sure that students are aware of these
technological changes. This challenge can be seen as the motivation
for this study, which is to examine the factors affecting computing
students’ awareness of the latest Information Technologies (ICTs).
The aim of this study is divided into two sub-objectives which are:
the selection of relevant theories and the design of a conceptual
model to support it as well as the empirical testing of the designed
model. The first objective is achieved by a review of existing
literature on technology adoption theories and models. The second
objective is achieved using a survey of computing students in the four
universities of the KwaZulu-Natal province of South Africa. Data
collected from this survey is analyzed using Statistical package for
the Social Science (SPSS) using descriptive statistics, ANOVA and
Pearson correlations. The main hypothesis of this study is that there is
a relationship between the demographics and the prior conditions of
the computing students and their awareness of general ICT trends and
of Digital Switch Over (DSO) a new technology which involves the
change from analog to digital television broadcasting in order to
achieve improved spectrum efficiency. The prior conditions of the
computing students that were considered in this study are students’
perceived exposure to career guidance and students’ perceived
curriculum currency. The results of this study confirm that gender,
ethnicity, and high school computing course affect students’
perceived curriculum currency while high school location affects
students’ awareness of DSO. The results of this study also confirm
that there is a relationship between students prior conditions and their
awareness of general ICT trends and DSO in particular.
Abstract: A retrospective study conducted at Christian Medical
College (CMC) Teaching Hospital, Vellore, India on 14th August
2014 to assess the accuracy of clinically estimated foetal weight upon
labour admission. Estimating foetal weight is a crucial factor in
assessing maternal and foetal complications during and after labour.
Medical notes of ninety-eight postnatal women who fulfilled the
inclusion criteria were studied to evaluate the correlation between
their recorded Estimated Foetal Weight (EFW) on admission and
actual birth weight (ABW) of the newborn after delivery. Data
concerning maternal and foetal demographics was also noted.
Accuracy was determined by absolute percentage error and
proportion of estimates within 10% of ABW. Actual birth weights
ranged from 950-4080g. A strong positive correlation between EFW
and ABW (r=0.904) was noted. Term deliveries (≥40 weeks) in the
normal weight range (2500-4000g) had a 59.5% estimation accuracy
(n=74) compared to pre-term (4000g) were underestimated by 25% (n=3) and low birthweight
(LBW) babies were overestimated by 12.7% (n=9). Registrars who
estimated foetal weight were accurate in babies within normal weight
ranges. However, there needs to be an improvement in predicting
weight of macrosomic and LBW foetuses. We have suggested the use
of an amended version of the Johnson’s formula for the Indian
population for improvement and a need to re-audit once
implemented.
Abstract: Polycyclic Aromatic Hydrocarbons (PAHs) are
formed mainly because of incomplete combustion of organic
materials during industrial, domestic activities or natural occurrence.
Their toxicity and contamination of terrestrial and aquatic ecosystem
have been established. However, with limited validity index, previous
research has focused on PAHs isomer pair ratios of variable
physicochemical properties in source identification. The objective of
this investigation was to determine the empirical validity of Pearson
Correlation Coefficient (PCC) and Cluster Analysis (CA) in PAHs
source identification along soil samples of different land uses.
Therefore, 16 PAHs grouped, as Endocrine Disruption Substances
(EDSs) were determined in 10 sample stations in top and sub soils
seasonally. PAHs was determined the use of Varian 300 gas
chromatograph interfaced with flame ionization detector. Instruments
and reagents used are of standard and chromatographic grades
respectively. PCC and CA results showed that the classification of
PAHs along pyrolitic and petrogenic organics used in source
signature is about the predominance PAHs in environmental matrix.
Therefore, the distribution of PAHs in the studied stations revealed
the presence of trace quantities of the vast majority of the sixteen
PAHs, which may ultimately inhabit the actual source signature
authentication. Therefore, factors to be considered when evaluating
possible sources of PAHs could be; type and extent of bacterial
metabolism, transformation products/substrates, and environmental
factors such as salinity, pH, oxygen concentration, nutrients, light
intensity, temperature, co-substrates, and environmental medium are
hereby recommended as factors to be considered when evaluating
possible sources of PAHs.
Abstract: Non-linear dynamic time history analysis is
considered as the most advanced and comprehensive analytical
method for evaluating the seismic response and performance of
multi-degree-of-freedom building structures under the influence of
earthquake ground motions. However, effective and accurate
application of the method requires the implementation of advanced
hysteretic constitutive models of the various structural components
including masonry infill panels. Sophisticated computational research
tools that incorporate realistic hysteresis models for non-linear
dynamic time-history analysis are not popular among the professional
engineers as they are not only difficult to access but also complex and
time-consuming to use. In addition, commercial computer programs
for structural analysis and design that are acceptable to practicing
engineers do not generally integrate advanced hysteretic models
which can accurately simulate the hysteresis behavior of structural
elements with a realistic representation of strength degradation,
stiffness deterioration, energy dissipation and ‘pinching’ under cyclic
load reversals in the inelastic range of behavior. In this scenario,
push-over or non-linear static analysis methods have gained
significant popularity, as they can be employed to assess the seismic
performance of building structures while avoiding the complexities
and difficulties associated with non-linear dynamic time-history
analysis. “Push-over” or non-linear static analysis offers a practical
and efficient alternative to non-linear dynamic time-history analysis
for rationally evaluating the seismic demands. The present paper is
based on the analytical investigation of the effect of distribution of
masonry infill panels over the elevation of planar masonry infilled
reinforced concrete [R/C] frames on the seismic demands using the
capacity spectrum procedures implementing nonlinear static analysis
[pushover analysis] in conjunction with the response spectrum
concept. An important objective of the present study is to numerically
evaluate the adequacy of the capacity spectrum method using
pushover analysis for performance based design of masonry infilled
R/C frames for near-field earthquake ground motions.
Abstract: Polymorphism is one of the main pillars of objectoriented
paradigm. It induces hidden forms of class dependencies
which may impact software quality, resulting in higher cost factor for
comprehending, debugging, testing, and maintaining the software. In
this paper, a new cognitive complexity metric called Cognitive
Weighted Polymorphism Factor (CWPF) is proposed. Apart from the
software structural complexity, it includes the cognitive complexity
on the basis of type. The cognitive weights are calibrated based on 27
empirical studies with 120 persons. A case study and experimentation
of the new software metric shows positive results. Further, a
comparative study is made and the correlation test has proved that
CWPF complexity metric is a better, more comprehensive, and more
realistic indicator of the software complexity than Abreu’s
Polymorphism Factor (PF) complexity metric.
Abstract: Hypertension is a common condition causing cardio
and cerebrovascular complications. Portugal has one of the highest
mortality rates from stroke and a high prevalence of hypertension.
Systolic Blood Pressure (SBP) is an important risk factor for
cardiovascular events (myocardial infarction and stroke) and
premature mortality, particularly in the elderly population. The
present study aims to estimate the prevalence of hypertension in a
Portuguese population living in a coastal city and to identify some of
its determinants (namely gender, age, the body mass index and
physical activity frequency). A total of 91 adults who attended three pharmacies of a coastal
city in the center of Portugal, between May and August of 2013 were
evaluated. Attendants who reported to have diabetes or taking
antihypertensive drugs in the 2 previous weeks were excluded from
the study. Sociodemographic factors, BMI, habits of exercise and BP
were assessed. Hypertension was defined as blood pressure ≥140/90
mmHg. The majority of the studied population was constituted by women
(75.8%), with a mean age of 54.2±1.6 years old, married or living in
civil union and that had completed secondary school or had higher
education (40%). They presented a mean BMI of 26.2±4.76 Kg/m2.,
and were sedentary. The mean BP was 127.0±17.77mmHg- 74.69 ±
9.53. In this population we found 4.3% of people with hypertension
and 16.1% with normal high blood pressure. Men exhibit a tendency to present higher systolic blood pressure
values than women. Of all the factors considered, SBP values also
tended to be higher with age and higher BMI values.
Despite the fact that the mean values of SBP did not present values
higher than 140 mmHg we must be concerned because the studied
population is undiagnosed for hypertension. Although this is a preliminary study, it might be a prelude to the
upcoming research about the underlying factors responsible for the
occurrence of SBP.
Abstract: The steady flow of a second order fluid through
constricted tube with slip velocity at wall is modeled and analyzed
theoretically. The governing equations are simplified by implying no
slip in radial direction. Based on Karman Pohlhausen procedure
polynomial solution for axial velocity profile is presented.
Expressions for pressure gradient, shear stress, separation and
reattachment points, and radial velocity are also calculated. The
effect of slip and no slip velocity on magnitude velocity, shear stress,
and pressure gradient are discussed and depicted graphically. It is
noted that when Reynolds number increases magnitude velocity of
the fluid decreases in both slip and no slip conditions. It is also found
that the wall shear stress, separation, and reattachment points are
strongly affected by Reynolds number.
Abstract: Mixed-use development is one of the most important
trends in new island house transformation along southeast coastal area
in China. Unique island geographical environment and profound
fishing village culture coexist for a long time in this. With artistic
creation for the purpose of the "live-work" houses are in a large
number of emergence, however, still lack of systematic strategy.
Based on space effect from marine resources to regional human
settlements, this article teases out the evolution regularity of island
settlement context and architectural form, then, puts forward the
formation mechanism and construction model of art island houses.
Thereby, to further explore space design method and site creation
strategy of mixed-use development.
Abstract: Detecting changes in multiple images of the same
scene has recently seen increased interest due to the many
contemporary applications including smart security systems, smart
homes, remote sensing, surveillance, medical diagnosis, weather
forecasting, speed and distance measurement, post-disaster forensics
and much more. These applications differ in the scale, nature, and
speed of change. This paper presents an application of image
processing techniques to implement a real-time change detection
system. Change is identified by comparing the RGB representation of
two consecutive frames captured in real-time. The detection threshold
can be controlled to account for various luminance levels. The
comparison result is passed through a filter before decision making to
reduce false positives, especially at lower luminance conditions. The
system is implemented with a MATLAB Graphical User interface
with several controls to manage its operation and performance.
Abstract: Cesium molybdates with general formula
CsMIII(MoO4)2, where MIII = Bi, Dy, Pr, Er, exhibit rich
polymorphism, and crystallize in a layered structure. These properties
cause intensive studies on cesium molybdates. CsBi(MoO4)2 was synthesized by microwave method by using
cerium sulphate, bismuth oxide and molybdenum (VI) oxide in an
appropriate molar ratio. Characterizations were done by x-ray
diffraction (XRD), fourier transform infrared (FTIR) spectroscopy,
scanning electron microscopy/energy dispersive analyze (SEM/EDS),
thermo gravimetric/differantial thermal analysis (TG/DTA).
Abstract: Adequate and reliable estimates of aquifer parameters
are of utmost importance for proper management of vital
groundwater resources. At present scenario, the ground water is
polluted because of industrial waste disposed over the land and the
contaminants are transported in the aquifer from one area to another
area, which is depending on the characteristics of the aquifer and
contaminants. To know the contaminant transport, the accurate
estimation of aquifer properties is highly needed. Conventionally,
these properties are estimated through pumping tests carried out on
water wells. The occurrence and movement of ground water in the
aquifer are characteristically defined by the aquifer parameters. The
pumping (aquifer) test is the standard technique for estimating
various hydraulic properties of aquifer systems, viz., transmissivity
(T), hydraulic conductivity (K), storage coefficient (S) etc., for which
the graphical method is widely used. The study area for conducting
pumping test is Pydibheemavaram Industrial area near the coastal
belt of Srikulam, AP, India. The main objective of the present work is
to estimate the aquifer properties for developing contaminant
transport model for the study area.
Abstract: Graphene, a single-atom sheet, has been considered as
the most promising material for making future nanoelectromechanical
systems as well as purely electrical switching with graphene
transistors. Graphene-based devices have advantages in scaled-up
device fabrication due to the recent progress in large area graphene
growth and lithographic patterning of graphene nanostructures. Here
we investigated its mechanical responses of circular graphene
nanoflake under the nanoindentation using classical molecular
dynamics simulations. A correlation between the load and the
indentation depth was constructed. The nanoindented force in this
work was applied to the center point of the circular graphene nanoflake
and then, the resonance frequency could be tuned by a nanoindented
depth. We found the hardening or the softening of the graphene
nanoflake during its nanoindented-deflections, and such properties
were recognized by the shift of the resonance frequency. The
calculated mechanical parameters in the force-vs-deflection plot were
in good agreement with previous experimental and theoretical works.
This proposed schematics can detect the pressure via the deflection
change or/and the resonance frequency shift, and also have great
potential for versatile applications in nanoelectromechanical systems.
Abstract: Background: To compare the thinning patterns of the
ganglion cell-inner plexiform layer (GCIPL) and peripapillary retinal
nerve fiber layer (pRNFL) as measured using Cirrus high-definition
optical coherence tomography (HD-OCT) in patients with visual field
(VF) defects that respect the vertical meridian. Methods: Twenty eyes of eleven patients with VF defects that
respect the vertical meridian were enrolled retrospectively. The
thicknesses of the macular GCIPL and pRNFL were measured using
Cirrus HD-OCT. The 5% and 1% thinning area index (TAI) was
calculated as the proportion of abnormally thin sectors at the 5% and
1% probability level within the area corresponding to the affected VF.
The 5% and 1% TAI were compared between the GCIPL and pRNFL
measurements. Results: The color-coded GCIPL deviation map showed a
characteristic vertical thinning pattern of the GCIPL, which is also
seen in the VF of patients with brain lesions. The 5% and 1% TAI
were significantly higher in the GCIPL measurements than in the
pRNFL measurements (all P < 0.01). Conclusions: Macular GCIPL analysis clearly visualized a
characteristic topographic pattern of retinal ganglion cell (RGC) loss
in patients with VF defects that respect the vertical meridian, unlike
pRNFL measurements. Macular GCIPL measurements provide more
valuable information than pRNFL measurements for detecting the
loss of RGCs in patients with retrograde degeneration of the optic
nerve fibers.
Abstract: The traditional rhythms of the West African country
of Guinea have played a centuries-long role in defining the different
people groups that make up the country. Throughout their history,
before and since colonization by the French, the different ethnicities
have used their traditional music as a distinct part of their historical
identities. That is starting to change. Guinea is an impoverished
nation created in the early twentieth-century with little regard for the
history and cultures of the people who were included. The traditional
rhythms of the different people groups and their heritages have
remained. Fifteen individual traditional Guinean rhythms were
chosen to represent popular rhythms from the four geographical
regions of Guinea. Each rhythm was traced back to its native village
and video recorded on-site by as many different local performing
groups as could be located. The cyclical patterns rhythms were
transcribed via a circular, spatial design and then copied into a box
notation system where sounds happening at the same time could be
studied. These rhythms were analyzed for their consistency-overperformance
in a Fundamental Rhythm Pattern analysis so rhythms
could be compared for how they are changing through different
performances. The analysis showed that the traditional rhythm
performances of the Middle and Forest Guinea regions were the most
cohesive and showed the least evidence of change between
performances. The role of music in each of these regions is both
limited and focused. The Coastal and High Guinea regions have
much in common historically through their ethnic history and
modern-day trade connections, but the rhythm performances seem to
be less consistent and demonstrate more changes in how they are
performed today. In each of these regions the role and usage of music
is much freer and wide-spread. In spite of advances being made as a
country, different ethnic groups still frequently only respond and
participate (dance and sing) to the music of their native ethnicity.
There is some evidence that this self-imposed musical barrier is
beginning to change and evolve, partially through the development of
better roads, more access to electricity and technology, the nationwide
Ebola health crisis, and a growing self-identification as a
unified nation.
Abstract: The growth in the demand of electrical energy is
leading to load on the Power system which increases the occurrence
of frequent oscillations in the system. The reason for the oscillations
is due to the lack of damping torque which is required to dominate
the disturbances of Power system. By using FACT devices, such as
Unified Power Flow Controller (UPFC) can control power flow,
reduce sub-synchronous resonances and increase transient stability.
Hence, UPFC is used to damp the oscillations occurred in Power
system. This research focuses on adapting the neuro fuzzy controller
for the UPFC design by connecting the infinite bus (SMIB - Single
machine Infinite Bus) to a linearized model of synchronous machine
(Heffron-Phillips) in the power system. This model gains the
capability to improve the transient stability and to damp the
oscillations of the system.
Abstract: The last two decades witnessed a movement towards
harmonization of international financial reporting standards (IFRS)
throughout the global economy. This investigation seeks to identify
the factors that could explain the adoption of IFRS by poor
jurisdictions. While there has been a considerable amount of
literature published on the effects and key drivers of IFRS adoption
in both developed and developing countries, little attention has been
paid to jurisdictions with less developed capital markets and low
income levels exclusively. Drawing upon the Institutional Isomorphism theory and analyzing
a sample of 45 poor jurisdictions between 2008 and 2013, the study
empirically shows that poor jurisdictions are driven by legitimacy
concerns rather than by economic reasoning to adopt an international
accounting perspective. This in turn has implications for the IASB, as
it should seek to influence institutional pressures within a particular
jurisdiction in order to promote IFRS adoption.