Characterization of Biodegradable Polycaprolactone Containing Titanium Dioxide Micro and Nanoparticles

Composites based on a biodegradable polycaprolactone (PCL) containing 0.5, 1.0 and 2.0 wt % of titanium dioxide (TiO2) micro and nanoparticles were prepared by melt mixing and the effect of filler type and contents on the thermal properties, dynamic-mechanical behaviour and morphology were investigated. Measurements of storage modulus and loss modulus by dynamic mechanical analysis (DMA) showed better results for microfilled PCL/TiO2 composites than nanofilled composites, with the same filler content. DSC analysis showed that the Tg and Tc of micro and nanocomposites were slightly lower than those of neat PCL. The crystallinity of the PCL increased with the addition of TiO2 micro and nanoparticles; however, the cc for the PCL was unchanged with micro TiO2 content. The thermal stability of PCL/TiO2 composites were characterized using thermogravimetric analysis (TGA). The initial weight loss (5 wt %) occurs at slightly higher temperature with micro and nano TiO2 addition and with increasing TiO2 content.

Enhanced Differentiation of Stromal Cells and Embryonic Stem Cells with Vitamin D3

In-vitro mouse co-culture of E14 embryonic stem cells (ESCs) and OP9 stromal cells can recapitulate the earliest stages of haematopoietic development, not accessible in human embryos, supporting both haemogenic precursors and their primitive haematopoietic progeny. 1α, 25-Dihydroxy-vitamin D3 (VD3) has been demonstrated to be a powerful differentiation inducer for a wide variety of neoplastic cells, and could enhance early differentiation of ESCs into blood cells in E14/OP9 co-culture. This study aims to ascertain whether VD3 is key in promoting differentiation and suppressing proliferation, by separately investigating the effects of VD3 on the proliferation phase of the E14 cell line and on stromal OP9 cells.The results showed that VD3 inhibited the proliferation of the cells in a dose-dependent manner, quantitatively by decreased cell number, and qualitatively by alkaline-phosphatase staining that revealed significant differences between VD3-treated and untreated cells, characterised by decreased enzyme expression (colourless cells). Propidium-iodide cell-cycle analyses showed no significant percentage change in VD3-treated E14 and OP9 cells within their G and S-phases, compared to the untreated controls, despite the increased percentage of G-phase compared to the S-phase in a dosedependent manner. These results with E14 and OP9 cells indicate that adequate VD3 concentration enhances cellular differentiation and inhibits proliferation. The results also suggest that if E14 and OP9 cells were co-cultured andVD3-treated, there would be furtherenhanced differentiation of ESCs into blood cells.

Micro-Penetrator for Canadian Planetary Exploration

Space exploration is a highly visible endeavour of humankind to seek profound answers to questions about the origins of our solar system, whether life exists beyond Earth, and how we could live on other worlds. Different platforms have been utilized in planetary exploration missions, such as orbiters, landers, rovers, and penetrators. Having low mass, good mechanical contact with the surface, ability to acquire high quality scientific subsurface data, and ability to be deployed in areas that may not be conducive to landers or rovers, Penetrators provide an alternative and complimentary solution that makes possible scientific exploration of hardly accessible sites (icy areas, gully sites, highlands etc.). The Canadian Space Agency (CSA) has put space exploration as one of the pillars of its space program, and established ExCo program to prepare Canada for future international planetary exploration. ExCo sets surface mobility as its focus and priority, and invests mainly in the development of rovers because of Canada's niche space robotics technology. Meanwhile, CSA is also investigating how micro-penetrators can help Canada to fulfill its scientific objectives for planetary exploration. This paper presents a review of the micro-penetrator technologies, past missions, and lessons learned. It gives a detailed analysis of the technical challenges of micro-penetrators, such as high impact survivability, high precision guidance navigation and control, thermal protection, communications, and etc. Then, a Canadian perspective of a possible micro-penetrator mission is given, including Canadian scientific objectives and priorities, potential instruments, and flight opportunities.

Statistical Models of Network Traffic

Model-based approaches have been applied successfully to a wide range of tasks such as specification, simulation, testing, and diagnosis. But one bottleneck often prevents the introduction of these ideas: Manual modeling is a non-trivial, time-consuming task. Automatically deriving models by observing and analyzing running systems is one possible way to amend this bottleneck. To derive a model automatically, some a-priori knowledge about the model structure–i.e. about the system–must exist. Such a model formalism would be used as follows: (i) By observing the network traffic, a model of the long-term system behavior could be generated automatically, (ii) Test vectors can be generated from the model, (iii) While the system is running, the model could be used to diagnose non-normal system behavior. The main contribution of this paper is the introduction of a model formalism called 'probabilistic regression automaton' suitable for the tasks mentioned above.

The Numerical Study of Low Level Jets Formation in South Eastern of Iran

The presence of cold air with the convergent topography of the Lut valley over the valley-s sloping terrain can generate Low Level Jets (LLJ). Moreover, the valley-parallel pressure gradients and northerly LLJ are produced as a result of the large-scale processes. In the numerical study the regional MM5 model was run leading to achieve an appropriate dynamical analysis of flows in the region for summer and winter. The results of this study show the presence of summer synoptical systems cause the formation of north-south pressure gradients in the valley which could be led to the blowing of winds with the velocity more than 14 ms-1 and vulnerable dust and wind storms lasting more than 120 days. Whereas the presence of cold air masses in the region in winter, cause the average speed of LLJs decrease. In this time downslope flows are noticeable in creating the night LLJs.

Sorting Primitives and Genome Rearrangementin Bioinformatics: A Unified Perspective

Bioinformatics and computational biology involve the use of techniques including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems usually on the molecular level. Research in computational biology often overlaps with systems biology. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and proteinprotein interactions, and the modeling of evolution. Various global rearrangements of permutations, such as reversals and transpositions,have recently become of interest because of their applications in computational molecular biology. A reversal is an operation that reverses the order of a substring of a permutation. A transposition is an operation that swaps two adjacent substrings of a permutation. The problem of determining the smallest number of reversals required to transform a given permutation into the identity permutation is called sorting by reversals. Similar problems can be defined for transpositions and other global rearrangements. In this work we perform a study about some genome rearrangement primitives. We show how a genome is modelled by a permutation, introduce some of the existing primitives and the lower and upper bounds on them. We then provide a comparison of the introduced primitives.

Knowledge and Attitude among Women and Men in Decision Making on Pap Smear Screening in Kelantan, Malaysia

This paper explores the knowledge and attitude of women and men in decision making on pap smear screening. This qualitative study recruited 52 respondents with 44 women and 8 men, using the purposive sampling with snowballing technique through indepth interviews. This study demonstrates several key findings: Female respondents have better knowledge compared to male. Most of the women perceived that pap smear screening is beneficial and important, but to proceed with the test is still doubtful. Male respondents were supportive in terms of sending their spouses to the health facilities or give more freedom to their wives to choose and making decision on their own health due to prominent reason that women know best on their own health. It is expected that the results from this study will provide useful guideline for healthcare providers to prepare any action/intervention to provide an extensive education to improve people-s knowledge and attitude towards pap smear.

Eclectic Rule-Extraction from Support Vector Machines

Support vector machines (SVMs) have shown superior performance compared to other machine learning techniques, especially in classification problems. Yet one limitation of SVMs is the lack of an explanation capability which is crucial in some applications, e.g. in the medical and security domains. In this paper, a novel approach for eclectic rule-extraction from support vector machines is presented. This approach utilizes the knowledge acquired by the SVM and represented in its support vectors as well as the parameters associated with them. The approach includes three stages; training, propositional rule-extraction and rule quality evaluation. Results from four different experiments have demonstrated the value of the approach for extracting comprehensible rules of high accuracy and fidelity.

Simulation Study of DFIG Wind Turbine under Grid Fault

During recent years wind turbine technology has undergone rapid developments. Growth in size and the optimization of wind turbines has enabled wind energy to become increasingly competitive with conventional energy sources. As a result today-s wind turbines participate actively in the power production of several countries around the world. These developments raise a number of challenges to be dealt with now and in the future. The penetration of wind energy in the grid raises questions about the compatibility of the wind turbine power production with the grid. In particular, the contribution to grid stability, power quality and behavior during fault situations plays therefore as important a role as the reliability. In the present work, we addressed two fault situations that have shown their influence on the generator and the behavior of the wind over the defects which are briefly discussed based on simulation results.

Informal Inferential Reasoning Using a Modelling Approach within a Computer-Based Simulation

The article investigates how 14- to 15- year-olds build informal conceptions of inferential statistics as they engage in a modelling process and build their own computer simulations with dynamic statistical software. This study proposes four primary phases of informal inferential reasoning for the students in the statistical modeling and simulation process. Findings show shifts in the conceptual structures across the four phases and point to the potential of all of these phases for fostering the development of students- robust knowledge of the logic of inference when using computer based simulations to model and investigate statistical questions.

Optimal Criteria for Non-Minimal Phase Plants

The paper describes the evaluation of quality of control for cases of controlled non-minimal phase plants. Control circuits containing non-minimal phase plants have different properties, they manifest reversed reaction at the beginning of unit step response. For these types of plants are developed special criterion of quality of control, which considers the difference and can be helpful for synthesis of optimal controller tuning. All results are clearly presented using Matlab/Simulink models.

Investigating Cultural, Artistic and Architectural Consequences of Mongolian Invasion of Iran and Establishment of Ilkhanate Dynasty

Social, culture and artistic status of a society in various historical eras is affected by numerous, and sometimes imposed, factors that better understanding requires analysis of such conditions. Throughout history Iran has been involved with determining and significant events that examining each of these events can improve the understanding of social conditions of this country in the intended time. Mongolian conquest of Iran is one of most significant events in the history of Iran with consequences that never left Iranian societies. During this tragic invasion and subsequent devastating wars, which led to establishment of Ilkhanate dynasty, numerous cultural and artistic changes occurred both in Mongolian conquerors and Iranian society. This study examines these changes with a glimpse towards art and architecture as important part of cultural aspects and social communication.

Project Base Learning for IT Personnel Resources Development using TVML

Using the animations video of teaching materials is an effective learning method. However, we thought that more effective learning method is to produce the teaching video by learners themselves. The learners who act as the producer must learn and understand well to produce and present video of teaching materials to others. The purpose of this study is to propose the project based learning (PBL) technique by co-producing video of IT (information technology) teaching materials. We used the T2V player to produce the video based on TVML a TV program description language. By proposed method, we have assigned the learners to produce the animations video for “National Examination for Information Processing Technicians (IPA examination)" in Japan, in order to get them learns various knowledge and skill on IT field. Experimental result showed that learning effect has occurred at the video production process that useful for IT personnel resources development.

Computational Investigation of Air-Gas Venturi Mixer for Powered Bi-Fuel Diesel Engine

In a bi-fuel diesel engine, the carburetor plays a vital role in switching from fuel gas to petrol mode operation and viceversa. The carburetor is the most important part of the fuel system of a diesel engine. All diesel engines carry variable venturi mixer carburetors. The basic operation of the carburetor mainly depends on the restriction barrel called the venturi. When air flows through the venturi, its speed increases and its pressure decreases. The main challenge focuses on designing a mixing device which mixes the supplied gas is the incoming air at an optimum ratio. In order to surmount the identified problems, the way fuel gas and air flow in the mixer have to be analyzed. In this case, the Computational Fluid Dynamics or CFD approach is applied in design of the prototype mixer. The present work is aimed at further understanding of the air and fuel flow structure by performing CFD studies using a software code. In this study for mixing air and gas in the condition that has been mentioned in continuance, some mixers have been designed. Then using of computational fluid dynamics, the optimum mixer has been selected. The results indicated that mixer with 12 holes can produce a homogenous mixture than those of 8-holes and 6-holes mixer. Also the result showed that if inlet convergency was smoother than outlet divergency, the mixture get more homogenous, the reason of that is in increasing turbulence in outlet divergency.

Asynchronous Microcontroller Simulation Model in VHDL

This article describes design of the 8-bit asynchronous microcontroller simulation model in VHDL. The model is created in ISE Foundation design tool and simulated in Modelsim tool. This model is a simple application example of asynchronous systems designed in synchronous design tools. The design process of creating asynchronous system with 4-phase bundled-data protocol and with matching delays is described in the article. The model is described in gate-level abstraction. The simulation waveform of the functional construction is the result of this article. Described construction covers only the simulation model. The next step would be creating synthesizable model to FPGA.

The Experimental Measurement of the LiBr Concentration of a Solar Absorption Machine

The excessive consumption of fossil energies (electrical energy) during summer caused by the technological development involves more and more climate warming. In order to reduce the worst impact of gas emissions produced from classical air conditioning, heat driven solar absorption chiller is pretty promising; it consists on using solar as motive energy which is clean and environmentally friendly to provide cold. Solar absorption machine is composed by four components using Lithium Bromide /water as a refrigerating couple. LiBr- water is the most promising in chiller applications due to high safety, high volatility ratio, high affinity, high stability and its high latent heat. The lithium bromide solution is constitute by the salt lithium bromide which absorbs water under certain conditions of pressure and temperature however if the concentration of the solution is high in the absorption chillers; which exceed 70%, the solution will crystallize. The main aim of this article is to study the phenomena of the crystallization and to evaluate how the dependence between the electric conductivity and the concentration which should be controlled.

Steel–CFRP Composite (CFRP Laminate Sandwiched between Mild Steel Strips) and It-s Behavior as Stirrup in Beams

In this present study, experimental work was conducted to study the effectiveness of newly innovated steel-CFRP composite (CFRP laminates sandwiched between two steel strips) as stirrups. A total numbers of eight concrete beams were tested under four point loads. Each beam measured 1600 mm long, 160mm width and 240 mm depth. The beams were reinforced with different shear reinforcements; one without stirrups, one with steel stirrups and six with different types and numbers of steel-CRFR stirrups. Test results indicated that the steel-CFRP stirrups had enhanced the shear strength capacity of beams. Moreover, the tests revealed that steel- CFRP stirrups reached to their ultimate tensile strength unlike FRP stirrups which rupture at much lower level than their ultimate strength as werereported in various researches.

Performance Comparison between Sliding Mode Control (SMC) and PD-PID Controllers for a Nonlinear Inverted Pendulum System

The objective of this paper is to compare the time specification performance between conventional controller PID and modern controller SMC for an inverted pendulum system. The goal is to determine which control strategy delivers better performance with respect to pendulum-s angle and cart-s position. The inverted pendulum represents a challenging control problem, which continually moves toward an uncontrolled state. Two controllers are presented such as Sliding Mode Control (SMC) and Proportional- Integral-Derivatives (PID) controllers for controlling the highly nonlinear system of inverted pendulum model. Simulation study has been done in Matlab Mfile and simulink environment shows that both controllers are capable to control multi output inverted pendulum system successfully. The result shows that Sliding Mode Control (SMC) produced better response compared to PID control strategies and the responses are presented in time domain with the details analysis.

Chaotic Oscillations of Diaphragm Supported by Nonlinear Springs with Hysteresis

This paper describes vibration analysis using the finite element method for a small earphone, especially for the diaphragm shape with a low-rigidity. The viscoelastic diaphragm is supported by multiple nonlinear concentrated springs with linear hysteresis damping. The restoring forces of the nonlinear springs have cubic nonlinearity. The finite elements for the nonlinear springs with hysteresis are expressed and are connected to the diaphragm that is modeled by linear solid finite elements in consideration of a complex modulus of elasticity. Further, the discretized equations in physical coordinates are transformed into the nonlinear ordinary coupled equations using normal coordinates corresponding to the linear natural modes. We computed the nonlinear stationary and non-stationary responses due to the internal resonance between modes with large amplitude in the nonlinear springs and elastic modes in the diaphragm. The non-stationary motions are confirmed as the chaos due to the maximum Lyapunov exponents with a positive number. From the time histories of the deformation distribution in the chaotic vibration, we identified nonlinear modal couplings.

Studying the Effect of Climate Change on the Conditions of Isfahan-s Province Tourism

Tourism is a phenomenon respected by the human communities since a long time ago. It has been evoloving continually based on a variety of social and economic needs and with respect to increasingly development of communication and considerable increase of tourist-s number and resulted exchange income has attained much out come such as employment for the communities. or the purpose of tourism development in this zone suitable times and locations need to be specified in the zone for the tourist-s attendance. One of the most important needs of the tourists is the knowledge of climate conditions and suitable times for sightseeing. In this survey, the climate trend condition has been identified for attending the tourists in Isfahan province using the modified tourism climate index (TCI) as well as SPSS, GIS, excel, surfer softwares. This index evoluates systematically the climate conditions for tourism affairs and activities using the monthly maximum mean parameters of daily temperature, daily mean temperature, minimum relative humidity, daily mean relative humidity, precipitation (mm), total sunny hours, wind speed and dust. The results obtaind using kendal-s correlation test show that the months January, February, March, April, May, June, July, August, September, October, November and December are significant and have an increasing trend that indicates the best condition for attending the tourists. S, P, T mean , T max and dust are estimated from 1976-2005 and do kendal-s correlation test again to see which parameter has been effective. Based on the test, we also observed on the effective parameters that the rate of dust in February, March, April, May, June, July, August, October and November is decreasing and precipitation in September and January is increasing and also the radiation rate in May and August is increasing that indicate a better condition of convenience. Maximum temperature in June is also decreasing. Isfahan province has two spring and fall peaks and the best places for tourism are in the north and western areas.