Abstract: The liver is the strongest regenerating organ of the
organism, and even with 2/3 surgically removed, it can regenerate
completely. Hence liver cirrhosis may only develop when the
regenerating system is off.
We present the results of a comparative study of structural and
functional characteristics of rat liver tissue under the conditions of
toxic liver cirrhosis development, induced by carbon tetrachloride,
and its prevention/treatment by natural compounds with antioxidant
and immune stimulating action. Studies were made on Wister rats,
weighing 120~140 g. Grape seeds extracts, separately and in
combination with well-known anticirrhotic drug ursodeoxycholic
acid (Urdoxa), have demonstrated effectiveness in prevention of liver
cirrhosis development and its treatment.
Abstract: Due to the large amount of information in the World
Wide Web (WWW, web) and the lengthy and usually linearly
ordered result lists of web search engines that do not indicate
semantic relationships between their entries, the search for topically
similar and related documents can become a tedious task. Especially,
the process of formulating queries with proper terms representing
specific information needs requires much effort from the user. This
problem gets even bigger when the user's knowledge on a subject and
its technical terms is not sufficient enough to do so. This article
presents the new and interactive search application DocAnalyser that
addresses this problem by enabling users to find similar and related
web documents based on automatic query formulation and state-ofthe-
art search word extraction. Additionally, this tool can be used to
track topics across semantically connected web documents.
Abstract: Kigelia africana (Lam.) Benth. (Bignoniaceae) is a
reputed traditional remedy for various human ailments such as skin
diseases, microbial infections, melanoma, stomach troubles,
metabolic disorders, malaria and general pains. In spite of the fruit
being widely used for purposes related to its antibacterial and
antifungal properties, the chemical constituents associated with the
activity have not been fully identified. To elucidate the active
principles, we evaluated the antimicrobial activity of fruit extracts
and purified fractions against Staphylococcus aureus, Enterococcus
faecalis, Moraxella catarrhalis, Escherichia coli, Candida albicans
and Candida tropicalis. Shade-dried fruits were powdered and
extracted with hydroalcoholic (1:1) mixture by soaking at room
temperature for 72 h. The crude extract was further fractionated by
column chromatography, with successive elution using hexane,
dichloromethane, ethyl acetate, acetone and methanol. The
dichloromethane and ethyl acetate fractions were combined and
subjected to column chromatography to furnish a wax and oil from
the eluates of 20% and 40% ethyl acetate in hexane, respectively. The
GC-MS and GC×GC-MS results revealed that linoleic acid, linolenic
acid, palmitic acid, arachidic acid and stearic acid were the major
constituents in both oil and wax. The crude hydroalcoholic extract
exhibited the strongest activity with MICs of 0.125-0.5 mg/mL,
followed by the ethyl acetate (MICs = 0.125-1.0 mg/mL),
dichloromethane (MICs = 0.250-2.0 mg/mL), hexane (MICs = 0.25-
2.0 mg/mL), acetone (MICs = 0.5-2.0 mg/mL) and methanol (MICs =
1.0-2.0 mg/mL), whereas the wax (MICs = 2.0-4.0 mg/mL) and oil
(MICs = 4.0-8.0 mg/mL) showed poor activity. The study concludes
that synergistic interactions of chemical constituents could be
responsible for the antimicrobial activity of K. africana fruits, which
needs a more holistic approach to understand the mechanism of its
antimicrobial activity.
Abstract: Due to the advancement of Internet technology, online
learning is widely used in higher education institutions. Online
learning offers several means of communication, including online
forum. Through online forum, students and instructors are able to
discuss and share their knowledge and expertise without having a
need to attend the face-to-face, ordinary classroom session. The
purposes of this study are to analyze the students’ levels of
participation and critical thinking, types of action and factors
influencing their participation in online forum. A total of 41
postgraduate students undertaking a course in educational technology
from a public university in Malaysia were involved in this study. In
this course, the students participated in a weekly online forum as part
of the course requirement. Based on the log data file extracted from
the online forum, the students’ type of actions (view, add, update,
delete posts) and their levels of participation (passive, moderate or
active) were identified. In addition, the messages posted in the forum
were analyzed to gauge their level of critical thinking. Meanwhile,
the factors that might influence their online forum participation were
measured using a 24-items questionnaire. Based on the log data, a
total of 105 posts were sent by the participants. In addition, the
findings show that (i) majority of the students are moderate
participants, with an average of two to three posts per person, (ii)
viewing posts are the most frequent type of action (85.1%), and
followed by adding post (9.7%). Furthermore, based on the posts
they made, the most frequent type of critical thinking observed was
justification (50 input or 19.0%), followed by linking ideas and
interpretation (47 input or 18%), and novelty (38 input or 14.4%).
The findings indicate that online forum allows for social interaction
and can be used to measure the students’ critical thinking skills. In
order to achieve this, monitoring students’ activities in the online
forum is recommended.
Abstract: Natural gas, as one of the most important sources of
energy for many of the industrial and domestic users all over the
world, has a complex, huge supply chain which is in need of heavy
investments in all the phases of exploration, extraction, production,
transportation, storage and distribution. The main purpose of supply
chain is to meet customers’ need efficiently and with minimum cost.
In this study, with the aim of minimizing economic costs, different
levels of natural gas supply chain in the form of a multi-echelon,
multi-period fuzzy linear programming have been modeled. In this
model, different constraints including constraints on demand
satisfaction, capacity, input/output balance and presence/absence of a
path have been defined. The obtained results suggest efficiency of the
recommended model in optimal allocation and reduction of supply
chain costs.
Abstract: Online forum is part of a Learning Management
System (LMS) environment in which students share their opinions.
This study attempts to investigate the perceptions of students towards
online forum and their patterns of listening behavior during the forum
interaction. The students’ perceptions were measured using a
questionnaire, in which seven dimensions were used involving online
experience, benefits of forum participation, cost of participation,
perceived ease of use, usefulness, attitude, and intention. Meanwhile,
their patterns of listening behaviors were obtained using the log file
extracted from the LMS. A total of 25 postgraduate students
undertaking a course were involved in this study, and their activities
in the forum session were recorded by the LMS and used as a log file.
The results from the questionnaire analysis indicated that the students
perceived that the forum is easy to use, useful, and bring benefits to
them. Also, they showed positive attitude towards online forum, and
they have the intention to use it in future. Based on the log data, the
participants were also divided into six clusters of listening behavior,
in which they are different in terms of temporality, breadth, depth and
speaking level. The findings were compared to previous clusters
grouping and future recommendations are also discussed.
Abstract: Hot aqueous and methanol extracts of the two selected
herbal medicines such are Vellarugu chooranam (V.C) and
Amukkirai Chooranam (A.C) were examined for total phenolic and
flavonoid contents and in vitro antioxidant activity using four
different methods. The total phenolic and flavonoid contents in
methanol extract of V.C were found to be higher (44.41±1.26mg
GAE/g; 174.44±9.32mg QE/g) than in the methanol extract of A.C
(20.56±0.67mg GAE/g; 7.21±0.85mg QE/g). Hot methanol and
aqueous extracts of both medicines showed low antioxidant activity
in DPPH, ABTS, and FRAP methods and Iron chelating activity not
found at highest possible concentration. V.C contains higher
concentrations of total phenolic and flavonoid contents than A.C and
can also exert greater antioxidant activity than A.C, although the
activities demonstrated were lower than the positive control Trolox.
The in vitro antioxidant activity was not related with the total
phenolic and flavonoid contents of the methanol and aqueous extracts
of both herbal medicines (A.C and V.C).
Abstract: A relationship between face and signature biometrics
is established in this paper. A new approach is developed to predict
faces from signatures by using artificial intelligence. A multilayer
perceptron (MLP) neural network is used to generate face details
from features extracted from signatures, here face is the physical
biometric and signatures is the behavioural biometric. The new
method establishes a relationship between the two biometrics and
regenerates a visible face image from the signature features.
Furthermore, the performance efficiencies of our new technique are
demonstrated in terms of minimum error rates compared to published
work.
Abstract: Persea declinata (Bl.) Kosterm is a member of the
Lauraceae family, widely distributed in Southeast Asia. It is from the
same genus with avocado (Persea americana Mill), which is widely
consumed as food and for medicinal purposes. In the present study,
we examined the anticancer properties of Persea declinata (Bl.)
Kosterm bark methanolic crude extract (PDM). PDM exhibited a
potent antiproliferative effect in MCF-7 human breast cancer cells,
with an IC50 value of 16.68 .g/mL after 48h of treatment. We
observed that PDM caused cell cycle arrest and subsequent apoptosis
in MCF-7 cells, as exhibited by increased population at G0/G1 phase,
higher lactate dehydrogenase (LDH) release, and DNA
fragmentation. Mechanistic studies showed that PDM caused
significant elevation in ROS production, leading to perturbation of
mitochondrial membrane potential, cell permeability, and activation
of caspases-3/7. On the other hand, real-time PCR and Western blot
analysis showed that PDM treatment increased the expression of the
proapoptotic molecule, Bax, but decreased the expression of
prosurvival proteins, Bcl-2 and Bcl-xL, in a dose-dependent manner.
These findings imply that PDM could inhibit proliferation in MCF-7
cells via cell cycle arrest and apoptosis induction, indicating its
potential as a therapeutic agent worthy of further development.
Abstract: Ficus deltoidea from the Moraceae family is a popular
medicinal herb in Malaysia. It possesses strong antioxidant and antiinflammatory
properties. In the present study, the anti-inflammatory
effects of F. deltoidea extract on UVB-irradiated HaCaT
Keratinocytes were investigated. HaCaT Keratinocytes were UVBirradiated
(12.5 mJ/cm3) and were treated with 0.05, 0.08 or 0.1% of
F. deltoidea extract. Cell viability following UVB irradiation was
significantly higher in the groups treated with the F. deltoidea extract
at doses of 0.05, 0.08 or 0.1% than in control group with UVB
irradiation only. Tumor necrosis factor-α (TNF-α), interleukin-1α
(IL-1α), interleukin-6 (IL-6) and cyclooxygenase (COX-2) play
primary roles in the inflammation process upon UV irradiation and
are known to be stimulated by UVB irradiation. Treatment with the
F. deltoidea extract dramatically inhibited the UV-induced TNF-α,
IL-1α, IL-6, and COX-2 expression. These results suggest that the F.
deltoidea extract inhibits the production of pro-inflammatory
cytokines and may be an effective protective agent for the treatment
of skin diseases.
Abstract: The aim of the present study is to investigate the
potential use of the selected seed oils. The oil was extracted using
Soxhlet apparatus and the physicochemical characteristics of the oil
determined using standard methods. The following results were
obtained for the physicochemical parameters analysed: for Egusi seed
oil, Oil yield 53.20%, Saponification value 178.03±1.25 mgKOH/g,
Iodine value 49.10±0.32 g I2/100g, Acid value 4.30±0.86 mgKOH/g,
and Peroxide value 5.80±0.27 meq/kg were obtained. For Pawpaw
seed oil, Oil yield 40.10%, Saponification value 24.13±3.93
mgKOH/g, Iodine value 24.87±0.19 g I2/100g, Acid value 9.46±0.40
mgKOH/g, and Peroxide value 3.12±1.22 meq/kg were obtained. For
Sweet orange seed oil, Oil yield 43.10%, Saponification value
106.30±2.37 mgKOH/g, Iodine value 37.08±0.04 g I2/100g, Acid
value 7.59±0.77 mgKOH/g, and Peroxide value 2.21±0.46 meq/kg
were obtained. From the obtained values of the determined
parameters, the oils can be extracted from the three selected seeds in
commercial quantities and that the egusi and sweet orange seed oils
may be utilized in the industrial soap production.
Abstract: Red River Gum (Eucalyptus camaldulensis) is a tree
of the genus Eucalyptus widely distributed in Algeria and in the
world. The value of its aromatic secondary metabolites offers new
perspectives in the pharmaceutical industry. This strategy can
contribute to the sustainable development of our country. Preliminary
tests performed on the essential oil of Eucalyptus camendulensis
showed that this oil has antibacterial activity vis-à-vis the bacterial
strains (Enterococcus feacalis, Enterobacter cloaceai, Proteus
microsilis, Escherichia coli, Klebsiella pneumonia, and Pseudomonas
aeruginosa) and antifungic (Fusarium sporotrichioide and Fusarium
graminearum). The culture medium used was nutrient broth Muller
Hinton. The interaction between the bacteria and the essential oil is
expressed by a zone of inhibition with diameters of MIC indirectly
expression of. And we used the PDA medium to determine the fungal
activity. The extraction of the aromatic fraction (essentially oilhydrolat)
of the fresh aerian part of the Eucalyptus camendulensis
was performed by hydrodistillation. The average essential oil yield is
0.99%. The antimicrobial and fungal study of the essential oil and
hydrosol showed a high inhibitory effect on the growth of pathogens.
Abstract: Malathion (ML) is a well known pesticide commonly
used in many agricultural and non-agricultural processes. Its toxicity
has been attributed primarily to the accumulation of acetylcholine
(Ach) at nerve junctions, due to the inhibition of acetylcholinesterase
(AChE). The aim of the current research was to study the protective
effect of the melissa plant extract against reproductive impairment
induced by malathion in 32 male albino rats, and the biological
experiment was divided into four groups (8 in each) that given
malathion (27 mg/kg; 1/50 of the LD50 for an oral dose) and/or
Melissa officinalis (MO) extract (200mg/kg/day) by gavages
technique. The sperm counts, sperm motility, sperm morphology,
FSH, LH, and testosterone levels had been determined in testes
homogenate at the end of the experiment. It is worthy to report that,
rats treated with melissa extract did not show a significant difference
when compared with the control group, while rats given malathion
alone had significantly lower sperm count, sperm motility, and
significantly higher abnormal sperm numbers, than the untreated
control rats as well as having significantly lower serum FSH, LH, and
testosterone levels compared with the control group. Administrations
of melissa extract restore all mentioned histological parameters
towards the control group and the melissa extract had a strong
positive protective effect against malathion toxicity. Results the of
biological parameters were confirmed by the histological
examination of rat testes and indicated that, both control and melissa
groups showing normal seminiferous tubules, while malathion group
testicular tissues had necrosis, edema in the seminiferous tubules and
degeneration of spermatogonial cells lining the seminiferous tubules
with incomplete spermatogenesis. The use of melissa against
malathion improved the histological picture and showing normal
seminiferous tubules with complete spermatogenesis and almost there
was no histopathological changes could be noted.
Abstract: The system is designed to show images which are
related to the query image. Extracting color, texture, and shape
features from an image plays a vital role in content-based image
retrieval (CBIR). Initially RGB image is converted into HSV color
space due to its perceptual uniformity. From the HSV image, Color
features are extracted using block color histogram, texture features
using Haar transform and shape feature using Fuzzy C-means
Algorithm. Then, the characteristics of the global and local color
histogram, texture features through co-occurrence matrix and Haar
wavelet transform and shape are compared and analyzed for CBIR.
Finally, the best method of each feature is fused during similarity
measure to improve image retrieval effectiveness and accuracy.
Abstract: This research proposes a novel reconstruction protocol
for restoring missing surfaces and low-quality edges and shapes in
photos of artifacts at historical sites. The protocol starts with the
extraction of a cloud of points. This extraction process is based on
four subordinate algorithms, which differ in the robustness and
amount of resultant. Moreover, they use different -but
complementary- accuracy to some related features and to the way
they build a quality mesh. The performance of our proposed protocol
is compared with other state-of-the-art algorithms and toolkits. The
statistical analysis shows that our algorithm significantly outperforms
its rivals in the resultant quality of its object files used to reconstruct
the desired model.
Abstract: One of the major goals of Spoken Dialog Systems
(SDS) is to understand what the user utters.
In the SDS domain, the Spoken Language Understanding (SLU)
Module classifies user utterances by means of a pre-definite
conceptual knowledge. The SLU module is able to recognize only the
meaning previously included in its knowledge base. Due the vastity
of that knowledge, the information storing is a very expensive
process.
Updating and managing the knowledge base are time-consuming
and error-prone processes because of the rapidly growing number of
entities like proper nouns and domain-specific nouns. This paper
proposes a solution to the problem of Name Entity Recognition
(NER) applied to a SDS domain. The proposed solution attempts to
automatically recognize the meaning associated with an utterance by
using the PANKOW (Pattern based Annotation through Knowledge
On the Web) method at runtime.
The method being proposed extracts information from the Web to
increase the SLU knowledge module and reduces the development
effort. In particular, the Google Search Engine is used to extract
information from the Facebook social network.
Abstract: Web search engines are designed to retrieve and
extract the information in the web databases and to return dynamic
web pages. The Semantic Web is an extension of the current web in
which it includes semantic content in web pages. The main goal of
semantic web is to promote the quality of the current web by
changing its contents into machine understandable form. Therefore,
the milestone of semantic web is to have semantic level information
in the web. Nowadays, people use different keyword- based search
engines to find the relevant information they need from the web.
But many of the words are polysemous. When these words are
used to query a search engine, it displays the Search Result Records
(SRRs) with different meanings. The SRRs with similar meanings are
grouped together based on Word Sense Disambiguation (WSD). In
addition to that semantic annotation is also performed to improve the
efficiency of search result records. Semantic Annotation is the
process of adding the semantic metadata to web resources. Thus the
grouped SRRs are annotated and generate a summary which
describes the information in SRRs. But the automatic semantic
annotation is a significant challenge in the semantic web. Here
ontology and knowledge based representation are used to annotate
the web pages.
Abstract: In this paper the issue of dimensionality reduction is
investigated in finger vein recognition systems using kernel Principal
Component Analysis (KPCA). One aspect of KPCA is to find the
most appropriate kernel function on finger vein recognition as there
are several kernel functions which can be used within PCA-based
algorithms. In this paper, however, another side of PCA-based
algorithms -particularly KPCA- is investigated. The aspect of
dimension of feature vector in PCA-based algorithms is of
importance especially when it comes to the real-world applications
and usage of such algorithms. It means that a fixed dimension of
feature vector has to be set to reduce the dimension of the input and
output data and extract the features from them. Then a classifier is
performed to classify the data and make the final decision. We
analyze KPCA (Polynomial, Gaussian, and Laplacian) in details in
this paper and investigate the optimal feature extraction dimension in
finger vein recognition using KPCA.
Abstract: Azadirachta excelsa or locally known as sentang are
frequently used as a traditional medicine by diabetes patients in
Malaysia. However, less attention has been given to their toxicity
effect. Thus, the study is an attempt to examine the protective effect
of A. excelsa on the pancreas and to determine possible toxicity
mediated by the extract. Diabetes was induced experimentally in rats
by high-fat-diet for 16 weeks followed by intraperitoneal injection of
streptozotocin at dosage of 35 mg/kg of body weight. Declination of
the fasting blood glucose level was observed after continuous
administration of A. excelsa for 14 days twice daily. This is due to the
refining structure of the pancreas. However, surprisingly, the plant
extract reduced the leukocytes, erythrocytes, hemoglobin, MCHC and
lymphocytes. In addition, the rat treated with the plant extract
exhibited increment in AST and eosinocytes level. Overall, the
finding shows that A. excelsa possesses antidiabetic activity by
improving the structure of pancreatic islet of Langerhans but
involved in ameliorating of hematology and biochemical parameters.
Abstract: In remote sensing, shadow causes problems in many
applications such as change detection and classification. It is caused
by objects which are elevated, thus can directly affect the accuracy of
information. For these reasons, it is very important to detect shadows
particularly in urban high spatial resolution imagery which created a
significant problem. This paper focuses on automatic shadow
detection based on a new spectral index for multispectral imagery
known as Shadow Detection Index (SDI). The new spectral index
was tested on different areas of WorldView-2 images and the results
demonstrated that the new spectral index has a massive potential to
extract shadows with accuracy of 94% effectively and automatically.
Furthermore, the new shadow detection index improved road
extraction from 82% to 93%.